Detailed information for compound 1746989

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 257.116 | Formula: C11H10Cl2N2O
  • H donors: 2 H acceptors: 1 LogP: 1.69 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C1N[C@H]2CNC[C@@H]2c2c1c(Cl)c(cc2)Cl
  • InChi: 1S/C11H10Cl2N2O/c12-7-2-1-5-6-3-14-4-8(6)15-11(16)9(5)10(7)13/h1-2,6,8,14H,3-4H2,(H,15,16)/t6-,8+/m1/s1
  • InChiKey: UFIHFWYXISGIHY-SVRRBLITSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0179 0.0269 0.0963
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0139 0.0192 0.0192
Onchocerca volvulus 0.0626 0.1126 0.4969
Onchocerca volvulus 0.0089 0.0096 0.0422
Brugia malayi Dopamine receptor protein 2 0.0626 0.1126 0.403
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0626 0.1126 0.117
Toxoplasma gondii transporter, cation channel family protein 0.0042 0.0006 0.0016
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0045 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Echinococcus multilocularis transfer RNA-Gly 0.0045 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0069 0.0057 0.0205
Echinococcus granulosus metabotropic glutamate receptor 2 0.0043 0.0007 0.0007
Schistosoma mansoni tyrosine kinase 0.0087 0.0091 0.0095
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0139 0.0192 0.0688
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0184 0.0279 0.029
Loa Loa (eye worm) hypothetical protein 0.0179 0.0269 0.0963
Loa Loa (eye worm) adenylyl cyclase 3 0.1217 0.2261 0.8093
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0139 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0069 0.0057 0.0205
Loa Loa (eye worm) apoptosis regulator protein 0.0802 0.1465 0.5242
Loa Loa (eye worm) hypothetical protein 0.0061 0.0042 0.0152
Onchocerca volvulus 0.0179 0.0269 0.1187
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0626 0.1126 0.117
Schistosoma mansoni hypothetical protein 0.0056 0.0033 0.0034
Brugia malayi Cation transporter family protein 0.0139 0.0192 0.0688
Echinococcus multilocularis adenylate cyclase 9 0.0525 0.0933 0.0933
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.525 1 1
Echinococcus multilocularis neuropeptide Y receptor 0.0626 0.1126 0.1126
Onchocerca volvulus 0.0069 0.0057 0.0252
Echinococcus granulosus g protein coupled receptor 0.0626 0.1126 0.1126
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0045 0.0011 0.004
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0069 0.0057 0.0057
Mycobacterium ulcerans hypothetical protein 0.0184 0.0279 1
Loa Loa (eye worm) hypothetical protein 0.0525 0.0933 0.334
Loa Loa (eye worm) kelch domain-containing protein family protein 0.027 0.0443 0.1585
Brugia malayi hypothetical protein 0.0626 0.1126 0.403
Onchocerca volvulus Putative nachr subunit 0.0139 0.0192 0.0848
Mycobacterium tuberculosis Probable transcriptional regulatory protein (probably LuxR/UhpA-family) 0.0039 0 0.5
Brugia malayi PAN domain containing protein 0.0179 0.0269 0.0963
Echinococcus granulosus potassium voltage gated channel protein 0.0519 0.0922 0.0922
Echinococcus granulosus voltage dependent calcium channel 0.0042 0.0006 0.0006
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0043 0.0008 0.0008
Onchocerca volvulus 0.0626 0.1126 0.4969
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0626 0.1126 0.117
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0139 0.0192 0.0192
Brugia malayi jmjC domain containing protein 0.0101 0.012 0.043
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0126 0.0167 0.0174
Echinococcus multilocularis G protein coupled receptor 139 0.1087 0.2011 0.2011
Echinococcus granulosus rhodopsin orphan GPCR 0.0626 0.1126 0.1126
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0008 0.0008
Echinococcus granulosus biogenic amine 5HT receptor 0.0626 0.1126 0.1126
Leishmania major extracellular receptor, putative 0.0043 0.0007 0.0155
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0139 0.0192 0.0192
Echinococcus granulosus tachykinin peptides receptor 99D 0.0626 0.1126 0.1126
Brugia malayi hypothetical protein 0.0626 0.1126 0.403
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0179 0.0269 0.075
Toxoplasma gondii PAN domain-containing protein 0.1908 0.3587 1
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0139 0.0192 0.0192
Echinococcus granulosus G protein coupled receptor 139 0.0626 0.1126 0.1126
Onchocerca volvulus 0.0626 0.1126 0.4969
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0043 0.0008 0.0008
Loa Loa (eye worm) melatonin receptor type 1A 0.0626 0.1126 0.403
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Echinococcus granulosus neuropeptide receptor 0.1087 0.2011 0.2011
Loa Loa (eye worm) hypothetical protein 0.0179 0.0269 0.0963
Loa Loa (eye worm) hypothetical protein 0.0139 0.0192 0.0688
Loa Loa (eye worm) hypothetical protein 0.007 0.006 0.0216
Loa Loa (eye worm) hypothetical protein 0.0069 0.0057 0.0205
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0043 0.0008 0.0008
Brugia malayi hypothetical protein 0.0069 0.0057 0.0205
Echinococcus multilocularis nAChR subunit 0.0139 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0171 0.0254 0.0908
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0045 0.0011 0.0011
Schistosoma mansoni cercarial elastase (S01 family) 0.0184 0.0279 0.029
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0139 0.0192 0.0688
Schistosoma mansoni hypothetical protein 0.0039 0.0001 0.0001
Schistosoma mansoni tyrosine kinase 0.0079 0.0078 0.0081
Brugia malayi PAN domain containing protein 0.0179 0.0269 0.0963
Brugia malayi PAN domain containing protein 0.0179 0.0269 0.0963
Brugia malayi RE15519p 0.0626 0.1126 0.403
Loa Loa (eye worm) integrin beta-2 0.1495 0.2794 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.0027 0.0098
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Toxoplasma gondii microneme protein MIC17C 0.0179 0.0269 0.075
Echinococcus granulosus glycine receptor subunit beta 0.0139 0.0192 0.0192
Echinococcus granulosus retinal guanylyl cyclase 2 0.0046 0.0014 0.0014
Leishmania major hypothetical protein, conserved 0.0282 0.0466 1
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Schistosoma mansoni amine GPCR 0.0626 0.1126 0.117
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0139 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Brugia malayi Adenylyl cyclase protein 0.0525 0.0933 0.334
Schistosoma mansoni tyrosine kinase 0.0079 0.0078 0.0081
Echinococcus multilocularis nAChR subunit 0.007 0.006 0.006
Toxoplasma gondii PAN domain-containing protein 0.0179 0.0269 0.075
Brugia malayi Trypsin family protein 0.0184 0.0279 0.0998
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Brugia malayi hypothetical protein 0.0069 0.0057 0.0205
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Brugia malayi Kelch motif family protein 0.027 0.0443 0.1585
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0039 0.0001 0.0001
Brugia malayi Receptor family ligand binding region containing protein 0.0176 0.0263 0.0943
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.007 0.006 0.0216
Loa Loa (eye worm) hypothetical protein 0.0139 0.0192 0.0688
Brugia malayi neuropeptide F receptor 0.0626 0.1126 0.403
Brugia malayi G protein-coupled receptor 0.0626 0.1126 0.403
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0087 0.0091 0.0091
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.058 0.1039 0.1079
Schistosoma mansoni tyrosine kinase 0.0087 0.0091 0.0095
Onchocerca volvulus 0.0626 0.1126 0.4969
Brugia malayi Metabotropic glutamate receptor precursor. 0.0043 0.0007 0.0026
Echinococcus multilocularis fibrillin 1 0.0051 0.0024 0.0024
Schistosoma mansoni voltage-gated cation channel 0.0126 0.0167 0.0174
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0046 0.0014 0.0014
Loa Loa (eye worm) neuropeptide F receptor 0.0626 0.1126 0.403
Loa Loa (eye worm) hypothetical protein 0.0043 0.0007 0.0026
Onchocerca volvulus 0.007 0.006 0.0266
Schistosoma mansoni nAChR subunit 0.0139 0.0192 0.02
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Schistosoma mansoni tyrosine kinase 0.0043 0.0008 0.0008
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0069 0.0057 0.0205
Loa Loa (eye worm) hypothetical protein 0.0179 0.0269 0.0963
Loa Loa (eye worm) hypothetical protein 0.0069 0.0057 0.0205
Loa Loa (eye worm) hypothetical protein 0.0184 0.0279 0.0998
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0626 0.1126 0.4969
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0043 0.0007 0.0007
Schistosoma mansoni metabotropic glutamate receptor 0.0043 0.0007 0.0008
Toxoplasma gondii hypothetical protein 0.0051 0.0024 0.0066
Onchocerca volvulus Neuropeptide F receptor homolog 0.0626 0.1126 0.4969
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0519 0.0922 0.0922
Echinococcus granulosus neuropeptides capa receptor 0.0626 0.1126 0.1126
Echinococcus granulosus biogenic amine 5HT receptor 0.0626 0.1126 0.1126
Echinococcus granulosus rhodopsin orphan GPCR 0.0626 0.1126 0.1126
Echinococcus granulosus tyrosine protein kinase Lyn 0.0043 0.0008 0.0008
Schistosoma mansoni neuropeptide F-like receptor 0.0626 0.1126 0.117
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0626 0.1126 0.1126
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0126 0.0167 0.0167
Loa Loa (eye worm) integrin alpha pat-2 0.0357 0.0611 0.2185
Echinococcus multilocularis adenylate cyclase 9 0.0096 0.0109 0.0109
Echinococcus granulosus 7tm_1 domain containing protein 0.0626 0.1126 0.1126
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0011 0.0012
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0045 0.0011 0.004
Schistosoma mansoni hypothetical protein 0.0802 0.1465 0.1521
Toxoplasma gondii microneme protein MIC4 0.0179 0.0269 0.075
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0184 0.0279 0.029
Toxoplasma gondii subtilisin SUB12 0.0179 0.0269 0.075
Brugia malayi protein-tyrosine kinase 0.0039 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0069 0.0057 0.0205
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0043 0.0007 0.0007
Mycobacterium tuberculosis Probable lignin peroxidase LipJ 0.0039 0 0.5
Schistosoma mansoni cercarial elastase (S01 family) 0.0184 0.0279 0.029
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0626 0.1126 0.117
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.007 0.006 0.0216
Echinococcus granulosus enteropeptidase 0.0184 0.0279 0.0279
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0626 0.1126 0.1126
Mycobacterium tuberculosis Probable conserved transmembrane protein 0.0039 0 0.5
Loa Loa (eye worm) RGC/RGC protein kinase 0.0176 0.0263 0.0943
Schistosoma mansoni nAChR subunit 0.0139 0.0192 0.02
Loa Loa (eye worm) hypothetical protein 0.0139 0.0192 0.0688
Schistosoma mansoni cercarial elastase (S01 family) 0.0184 0.0279 0.029
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0139 0.0192 0.0688
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0184 0.0279 0.029
Loa Loa (eye worm) hypothetical protein 0.0139 0.0192 0.0688
Schistosoma mansoni cercarial elastase (S01 family) 0.0184 0.0279 0.029
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0139 0.0192 0.0192
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0184 0.0279 0.029
Brugia malayi hypothetical protein 0.0626 0.1126 0.403
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0046 0.0014 0.0014
Echinococcus granulosus shaker cognate 0.0045 0.0011 0.0011
Echinococcus granulosus rhodopsin orphan GPCR 0.0626 0.1126 0.1126
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.0031 0.0112
Loa Loa (eye worm) hypothetical protein 0.0069 0.0057 0.0205
Echinococcus multilocularis fmrfamide receptor 0.0626 0.1126 0.1126
Schistosoma mansoni protein kinase 0.0176 0.0263 0.0274
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0069 0.0057 0.0057
Onchocerca volvulus 0.122 0.2266 1
Brugia malayi Muscle positioning protein 4 0.0184 0.0278 0.0995
Giardia lamblia Neurogenic locus Notch protein precursor 0.0051 0.0024 1
Giardia lamblia High cysteine protein 0.0051 0.0024 1
Schistosoma mansoni adenoreceptor 0.0626 0.1126 0.117
Loa Loa (eye worm) acetylcholine receptor protein 0.0069 0.0057 0.0205
Echinococcus multilocularis glutamate receptor 2 0.0043 0.0007 0.0007
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0626 0.1126 0.403
Echinococcus multilocularis sex peptide receptor 0.0626 0.1126 0.1126
Toxoplasma gondii hypothetical protein 0.0179 0.0269 0.075
Echinococcus granulosus glycine receptor subunit alpha 1 0.0139 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0186 0.0282 0.101
Loa Loa (eye worm) hypothetical protein 0.0139 0.0192 0.0688
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0626 0.1126 0.1126
Onchocerca volvulus 0.058 0.1039 0.4582
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0139 0.0192 0.0688
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0139 0.0192 0.0192
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0802 0.1465 0.1465
Echinococcus multilocularis voltage gated potassium channel 0.0045 0.0011 0.0011
Echinococcus granulosus Mastin 0.0184 0.0279 0.0279
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0043 0.0007 0.0007
Echinococcus granulosus adenylate cyclase 9 0.0525 0.0933 0.0933
Onchocerca volvulus 0.0626 0.1126 0.4969
Mycobacterium leprae Probable conserved transmembrane protein 0.0039 0 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.0626 0.1126 0.1126
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0626 0.1126 0.1126
Mycobacterium leprae possible transcriptional regulatory protein 0.0039 0 0.5
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0043 0.0008 0.0008
Echinococcus granulosus tyrosine protein kinase Src42A 0.0043 0.0008 0.0008
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0626 0.1126 0.117
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0043 0.0008 0.0008
Toxoplasma gondii PAN domain-containing protein 0.1908 0.3587 1
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0126 0.0167 0.0167
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0184 0.0279 0.0998
Echinococcus multilocularis rhodopsin orphan GPCR 0.0626 0.1126 0.1126
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0126 0.0167 0.0599
Brugia malayi putative neuropeptide receptor NPR1 0.0626 0.1126 0.403
Loa Loa (eye worm) PAN domain-containing protein 0.0179 0.0269 0.0963
Echinococcus granulosus voltage gated potassium channel 0.0045 0.0011 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0626 0.1126 0.1126
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0139 0.0192 0.0688
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0139 0.0192 0.0688
Echinococcus multilocularis integrin alpha ps 0.0357 0.0611 0.0611
Echinococcus multilocularis Mastin 0.0184 0.0279 0.0279
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0069 0.0057 0.0205
Echinococcus granulosus rhodopsin orphan GPCR 0.0626 0.1126 0.1126
Loa Loa (eye worm) hypothetical protein 0.0139 0.0192 0.0688
Onchocerca volvulus 0.0626 0.1126 0.4969
Brugia malayi Cation transporter family protein 0.0139 0.0192 0.0688
Echinococcus granulosus insulin receptor 0.0054 0.0029 0.0029
Schistosoma mansoni opsin-like receptor 0.0626 0.1126 0.117
Brugia malayi Tachykinin-like peptides receptor 99D 0.0626 0.1126 0.403
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0626 0.1126 0.117
Brugia malayi hypothetical protein 0.0039 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Schistosoma mansoni tyrosine kinase 0.0054 0.0029 0.003
Schistosoma mansoni integrin alpha-ps 0.0186 0.0282 0.0293
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0184 0.0279 0.0279
Brugia malayi hypothetical protein 0.0043 0.0007 0.0026
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0802 0.1465 0.5242
Schistosoma mansoni hypothetical protein 0.0184 0.0279 0.029
Loa Loa (eye worm) hypothetical protein 0.0043 0.0007 0.0026
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0626 0.1126 0.117
Schistosoma mansoni opsin-like receptor 0.0626 0.1126 0.117
Brugia malayi hypothetical protein 0.0626 0.1126 0.403
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0046 0.0014 0.0049
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0139 0.0192 0.0192
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0139 0.0192 0.0688
Echinococcus granulosus glycine receptor subunit alpha 1 0.0139 0.0192 0.0192
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0802 0.1465 0.1465
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0626 0.1126 0.117
Echinococcus multilocularis rhodopsin orphan GPCR 0.0626 0.1126 0.1126
Brugia malayi hypothetical protein 0.0241 0.0389 0.1391
Echinococcus granulosus tyrosine protein kinase Fyn 0.0043 0.0008 0.0008
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0519 0.0922 0.3299
Onchocerca volvulus 0.0626 0.1126 0.4969
Echinococcus multilocularis dro:myosuppressin receptor 0.0626 0.1126 0.1126
Brugia malayi Trypsin family protein 0.122 0.2266 0.8111
Echinococcus multilocularis insulin receptor 0.0054 0.0029 0.0029
Schistosoma mansoni biogenic amine receptor 0.0626 0.1126 0.117
Schistosoma mansoni hypothetical protein 0.0626 0.1126 0.117
Onchocerca volvulus 0.0179 0.0269 0.1187
Echinococcus granulosus adam 0.0051 0.0024 0.0024
Brugia malayi Serotonin receptor 0.0626 0.1126 0.403
Echinococcus granulosus allatostatin A receptor 0.0626 0.1126 0.1126
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0176 0.0263 0.1162
Loa Loa (eye worm) hypothetical protein 0.1109 0.2054 0.735
Loa Loa (eye worm) hypothetical protein 0.0184 0.0279 0.0998
Loa Loa (eye worm) TYRA-2 protein 0.0626 0.1126 0.403
Echinococcus multilocularis neuropeptides capa receptor 0.0626 0.1126 0.1126
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0043 0.0007 0.0007
Echinococcus granulosus adenylate cyclase type IX 0.0788 0.1437 0.1437
Echinococcus granulosus g-protein coupled receptor 0.0626 0.1126 0.1126
Schistosoma mansoni integrin beta subunit 0.0936 0.1721 0.1788
Schistosoma mansoni nAChR subunit 0.0069 0.0057 0.0059
Echinococcus multilocularis neuropeptide receptor A26 0.0626 0.1126 0.1126
Trichomonas vaginalis teneurin and N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase, putative 0.0051 0.0024 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0626 0.1126 0.1126
Brugia malayi EGF-like domain containing protein 0.0051 0.0024 0.0085
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0626 0.1126 0.1126
Loa Loa (eye worm) hypothetical protein 0.0069 0.0057 0.0205
Loa Loa (eye worm) TK/ROR protein kinase 0.0289 0.048 0.1717
Loa Loa (eye worm) hypothetical protein 0.0139 0.0192 0.0688
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0045 0.0011 0.0011
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0139 0.0192 0.02
Brugia malayi Serotonin receptor 0.1181 0.2192 0.7846
Brugia malayi hypothetical protein 0.0626 0.1126 0.403
Onchocerca volvulus 0.0184 0.0279 0.123
Giardia lamblia Tenascin-X 0.0051 0.0024 1
Loa Loa (eye worm) hypothetical protein 0.007 0.006 0.0216
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Echinococcus multilocularis glycine receptor subunit beta 0.0139 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0179 0.0269 0.0963
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0139 0.0192 0.0192
Onchocerca volvulus 0.0184 0.0278 0.1227
Loa Loa (eye worm) hypothetical protein 0.058 0.1039 0.3717
Brugia malayi putative neuropeptide receptor 0.0626 0.1126 0.403
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0626 0.1126 0.117
Loa Loa (eye worm) hypothetical protein 0.0051 0.0024 0.0085
Brugia malayi G protein-coupled receptor F59B2.13 0.0626 0.1126 0.403
Loa Loa (eye worm) hypothetical protein 0.0282 0.0466 0.1668
Echinococcus multilocularis sodium channel protein 0.0065 0.005 0.005
Schistosoma mansoni hypothetical protein 0.0184 0.0279 0.029
Schistosoma mansoni amine GPCR 0.0626 0.1126 0.117
Schistosoma mansoni nAChR subunit 0.0139 0.0192 0.02
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0626 0.1126 0.117
Echinococcus granulosus sex peptide receptor 0.0626 0.1126 0.1126
Echinococcus multilocularis neuropeptides capa receptor 0.0626 0.1126 0.1126
Echinococcus granulosus epidermal growth factor receptor 0.0087 0.0091 0.0091
Onchocerca volvulus 0.0626 0.1126 0.4969
Brugia malayi Melatonin receptor type 1A 0.0626 0.1126 0.403
Loa Loa (eye worm) TK/EGFR protein kinase 0.0156 0.0224 0.0801
Loa Loa (eye worm) hypothetical protein 0.0043 0.0007 0.0026
Schistosoma mansoni tyrosine kinase 0.0079 0.0078 0.0081
Schistosoma mansoni nAChR subunit 0.0139 0.0192 0.02
Brugia malayi PAN domain containing protein 0.0179 0.0269 0.0963
Loa Loa (eye worm) TK/INSR protein kinase 0.0054 0.0029 0.0104
Toxoplasma gondii kringle domain-containing protein 0.0282 0.0466 0.1299
Loa Loa (eye worm) hypothetical protein 0.0184 0.0279 0.0998
Brugia malayi adenylate cyclase, type IX 0.0096 0.0109 0.0389
Echinococcus granulosus tm gpcr rhodopsin 0.0626 0.1126 0.1126
Loa Loa (eye worm) hypothetical protein 0.122 0.2266 0.8111
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Echinococcus granulosus neuropeptides capa receptor 0.0626 0.1126 0.1126
Brugia malayi Furin-like cysteine rich region family protein 0.0156 0.0224 0.0801
Echinococcus granulosus potassium voltage gated channel protein 0.0045 0.0011 0.0011
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0069 0.0057 0.0205
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Giardia lamblia hypothetical protein 0.0051 0.0024 1
Toxoplasma gondii PAN domain-containing protein 0.0179 0.0269 0.075
Brugia malayi Receptor family ligand binding region containing protein 0.0043 0.0007 0.0026
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0626 0.1126 0.403
Echinococcus granulosus neuropeptide s receptor 0.0626 0.1126 0.1126
Loa Loa (eye worm) hypothetical protein 0.0179 0.0269 0.0963
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0139 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0241 0.0389 0.1391
Schistosoma mansoni cercarial elastase (S01 family) 0.0184 0.0279 0.029
Loa Loa (eye worm) hypothetical protein 0.0171 0.0254 0.0908
Brugia malayi Integrin beta pat-3 precursor 0.1495 0.2794 1
Loa Loa (eye worm) SRC-1 0.0043 0.0008 0.0028
Brugia malayi Dopamine receptor 0.0626 0.1126 0.403
Echinococcus granulosus neuropeptide Y receptor 0.0626 0.1126 0.1126
Brugia malayi hypothetical protein 0.0069 0.0057 0.0205
Loa Loa (eye worm) RGC/RGC protein kinase 0.0046 0.0014 0.0049
Onchocerca volvulus 0.018 0.027 0.1191
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0139 0.0192 0.0688
Echinococcus multilocularis potassium voltage gated channel protein 0.0519 0.0922 0.0922
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0011 0.0012
Loa Loa (eye worm) voltage-gated potassium channel 0.0045 0.0011 0.004
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0046 0.0014 0.0049
Brugia malayi PAN domain containing protein 0.0179 0.0269 0.0963
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0139 0.0192 0.0688
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0626 0.1126 0.117
Brugia malayi Protein kinase domain containing protein 0.0289 0.048 0.1717
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0139 0.0192 0.0688
Loa Loa (eye worm) GABA receptor subunit 0.007 0.006 0.0216
Brugia malayi SRC-1 0.0043 0.0008 0.0028
Loa Loa (eye worm) hypothetical protein 0.007 0.006 0.0216
Brugia malayi hypothetical protein 0.0626 0.1126 0.403
Echinococcus multilocularis serotonin receptor 0.0626 0.1126 0.1126
Brugia malayi hypothetical protein 0.0184 0.0279 0.0998
Schistosoma mansoni neurotransmitter gated ion channel 0.007 0.006 0.0063
Brugia malayi SEA domain containing protein 0.018 0.027 0.0966
Onchocerca volvulus 0.058 0.1039 0.4582
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0126 0.0167 0.0167
Onchocerca volvulus 0.0626 0.1126 0.4969
Brugia malayi sulfakinin receptor protein 0.0626 0.1126 0.403
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0626 0.1126 0.1126
Brugia malayi Protein kinase domain containing protein 0.0054 0.0029 0.0104
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0069 0.0057 0.0057
Schistosoma mansoni nAChR subunit 0.0139 0.0192 0.02
Onchocerca volvulus 0.0179 0.0269 0.1187
Echinococcus multilocularis conserved hypothetical protein 0.0833 0.1525 0.1525
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0069 0.0057 0.0205
Echinococcus granulosus integrin alpha ps 0.0171 0.0254 0.0254
Echinococcus multilocularis glutamate receptor 2 0.0043 0.0007 0.0007
Mycobacterium tuberculosis Possible adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase) 0.0039 0 0.5
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0139 0.0192 0.02
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.122 0.2266 0.2354
Schistosoma mansoni myosin xvIII 0.0626 0.1126 0.117
Loa Loa (eye worm) RGC/RGC protein kinase 0.0176 0.0263 0.0943
Echinococcus multilocularis receptor type guanylyl cyclase 0.0176 0.0263 0.0263
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0497 0.0879 0.0879
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0139 0.0192 0.0688
Echinococcus granulosus receptor type guanylyl cyclase 0.0176 0.0263 0.0263
Schistosoma mansoni cercarial elastase (S01 family) 0.0184 0.0279 0.029
Brugia malayi Trypsin family protein 0.0184 0.0279 0.0998
Onchocerca volvulus 0.0626 0.1126 0.4969
Loa Loa (eye worm) trypsin family protein 0.0184 0.0279 0.0998
Echinococcus multilocularis potassium voltage gated channel protein 0.0045 0.0011 0.0011
Giardia lamblia Tenascin-37 0.0051 0.0024 1
Loa Loa (eye worm) DOMON domain-containing protein 0.018 0.027 0.0966
Onchocerca volvulus 0.0139 0.0192 0.0848
Schistosoma mansoni integrin alpha-ps 0.0357 0.0611 0.0634
Schistosoma mansoni growth hormone secretagogue receptor 0.0626 0.1126 0.117
Entamoeba histolytica hypothetical protein 0.0043 0.0007 0.1047
Onchocerca volvulus 0.0043 0.0007 0.0032
Onchocerca volvulus 0.0184 0.0279 0.123
Echinococcus multilocularis rhodopsin orphan GPCR 0.0626 0.1126 0.1126
Onchocerca volvulus 0.0139 0.0192 0.0848
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.007 0.006 0.0216
Echinococcus multilocularis neuropeptide FF receptor 2 0.0626 0.1126 0.1126
Echinococcus granulosus epidermal growth factor receptor 0.0156 0.0224 0.0224
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0043 0.0007 0.0026
Echinococcus multilocularis integrin alpha ps 0.0171 0.0254 0.0254
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0054 0.0029 0.0029
Echinococcus granulosus 7TM GPCR rhodopsin 0.0626 0.1126 0.1126
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0626 0.1126 0.1126
Brugia malayi EGF-like domain containing protein 0.0051 0.0024 0.0085
Echinococcus granulosus nmda type glutamate receptor 0.0043 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0043 0.0007 0.0026
Brugia malayi Kringle domain containing protein 0.0282 0.0466 0.1668
Echinococcus granulosus atrial natriuretic peptide receptor 0.013 0.0175 0.0175
Loa Loa (eye worm) hypothetical protein 0.0061 0.0042 0.0152
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0139 0.0192 0.0192
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0802 0.1465 0.1465
Echinococcus granulosus peptide allatostatin:somatostatin 0.0626 0.1126 0.1126
Loa Loa (eye worm) hypothetical protein 0.007 0.006 0.0216
Echinococcus granulosus orexin receptor type 2 0.0626 0.1126 0.1126
Loa Loa (eye worm) LGC-31 protein 0.0139 0.0192 0.0688
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0626 0.1126 0.1126
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Echinococcus granulosus retinal guanylyl cyclase 2 0.0046 0.0014 0.0014
Schistosoma mansoni nAChR subunit 0.0139 0.0192 0.02
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0626 0.1126 0.1126
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0126 0.0167 0.0167
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0139 0.0192 0.0688
Loa Loa (eye worm) calcium channel 0.0126 0.0167 0.0599
Schistosoma mansoni neuropeptide receptor 0.1087 0.2011 0.2089
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0069 0.0057 0.0057
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0043 0.0008 0.0008
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0626 0.1126 0.403
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.007 0.006 0.0216
Toxoplasma gondii PAN/Apple domain-containing protein 0.0179 0.0269 0.075
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.0031 0.0112
Onchocerca volvulus 0.018 0.027 0.1191
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0139 0.0192 0.0688
Brugia malayi Trypsin-like protease protein 5 0.0184 0.0279 0.0998
Loa Loa (eye worm) hypothetical protein 0.0096 0.0109 0.0389
Echinococcus multilocularis g protein coupled receptor 0.0626 0.1126 0.1126
Brugia malayi follicle stimulating hormone receptor 0.0626 0.1126 0.403
Loa Loa (eye worm) PAN domain-containing protein 0.0179 0.0269 0.0963
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0046 0.0014 0.0014
Echinococcus multilocularis adam 0.0051 0.0024 0.0024
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0043 0.0008 0.0008
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0184 0.0279 0.029
Brugia malayi hypothetical protein 0.0069 0.0057 0.0205
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.1148 0.2128 0.9391
Loa Loa (eye worm) hypothetical protein 0.0139 0.0192 0.0688
Loa Loa (eye worm) G-protein coupled receptor 0.0626 0.1126 0.403
Onchocerca volvulus 0.0626 0.1126 0.4969
Loa Loa (eye worm) ACC-1 protein 0.0139 0.0192 0.0688
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0626 0.1126 0.403
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Brugia malayi hypothetical protein 0.0626 0.1126 0.403
Schistosoma mansoni tyrosine kinase 0.0054 0.0029 0.003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0626 0.1126 0.117
Echinococcus multilocularis allatostatin A receptor 0.0626 0.1126 0.1126
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0139 0.0192 0.0688
Loa Loa (eye worm) hypothetical protein 0.0055 0.0031 0.0112
Echinococcus multilocularis neuropeptide receptor 0.0626 0.1126 0.1126
Schistosoma mansoni biogenic amine (5HT) receptor 0.0626 0.1126 0.117
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0626 0.1126 0.1126
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0626 0.1126 0.403
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0626 0.1126 0.117
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0045 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Schistosoma mansoni cercarial elastase (S01 family) 0.0184 0.0279 0.029
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Loa Loa (eye worm) G-protein coupled receptor 0.0626 0.1126 0.403
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Loa Loa (eye worm) hypothetical protein 0.0045 0.0011 0.004
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0139 0.0192 0.0688
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0626 0.1126 0.117
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0626 0.1126 0.403
Loa Loa (eye worm) hypothetical protein 0.0069 0.0057 0.0205
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0043 0.0008 0.0008
Echinococcus granulosus tm gpcr rhodopsin 0.0626 0.1126 0.1126
Brugia malayi Dopamine receptor protein 1 0.0626 0.1126 0.403
Onchocerca volvulus 0.0179 0.0269 0.1187
Schistosoma mansoni jumonji domain containing protein 0.0081 0.008 0.0083
Loa Loa (eye worm) PAN domain-containing protein 0.0179 0.0269 0.0963
Loa Loa (eye worm) hypothetical protein 0.0184 0.0278 0.0995
Loa Loa (eye worm) hypothetical protein 0.0043 0.0007 0.0026
Schistosoma mansoni serine-type protease inhibitor 0.5056 0.9627 1
Echinococcus granulosus tyrosine protein kinase Src64B 0.0043 0.0008 0.0008
Onchocerca volvulus 0.0184 0.0279 0.123
Schistosoma mansoni protein tyrosine kinase 0.0046 0.0014 0.0014
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0045 0.0011 0.0011
Brugia malayi Guanylyl cyclase protein 23 0.0089 0.0096 0.0342
Brugia malayi larval opioid receptor 0.0626 0.1126 0.403
Schistosoma mansoni glutamate receptor NMDA 0.0043 0.0007 0.0008
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0101 0.012 0.012
Echinococcus multilocularis shaker cognate 0.0045 0.0011 0.0011
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0139 0.0192 0.0688
Schistosoma mansoni neurotransmitter gated ion channel 0.0069 0.0057 0.0059
Echinococcus granulosus rhodopsin orphan GPCR 0.0626 0.1126 0.1126
Brugia malayi G-protein coupled receptor 0.0626 0.1126 0.403
Echinococcus granulosus fmrfamide receptor 0.0626 0.1126 0.1126
Brugia malayi excitatory GABA receptor EXP-1A 0.0139 0.0192 0.0688
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0626 0.1126 0.117
Echinococcus multilocularis rhodopsin orphan GPCR 0.0626 0.1126 0.1126
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0802 0.1465 0.1465
Loa Loa (eye worm) voltage-dependent calcium channel 0.0042 0.0006 0.002
Loa Loa (eye worm) ACC-1 protein 0.0139 0.0192 0.0688
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0045 0.0011 0.0011
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0043 0.0008 0.0008
Echinococcus multilocularis epidermal growth factor receptor 0.0156 0.0224 0.0224
Echinococcus granulosus glycine receptor subunit beta 0.0139 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0139 0.0192 0.0688
Onchocerca volvulus 0.0179 0.0269 0.1187
Schistosoma mansoni nAChR subunit 0.0139 0.0192 0.02
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0069 0.0057 0.0205
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Schistosoma mansoni tyrosine kinase 0.005 0.0021 0.0022
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0139 0.0192 0.0192
Brugia malayi EGF-like domain containing protein 0.0051 0.0024 0.0085
Schistosoma mansoni hypothetical protein 0.0626 0.1126 0.117
Schistosoma mansoni acetylcholine receptor-related 0.0069 0.0057 0.0059
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0126 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.007 0.006 0.0216
Loa Loa (eye worm) hypothetical protein 0.0519 0.0922 0.3299
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0139 0.0192 0.0688
Echinococcus granulosus tyrosine protein kinase Fyn 0.0043 0.0008 0.0008
Echinococcus granulosus tyrosine kinase 0.0039 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.018 0.027 0.0966
Onchocerca volvulus 0.0184 0.0279 0.123
Echinococcus multilocularis orexin receptor type 2 0.0626 0.1126 0.1126
Echinococcus multilocularis epidermal growth factor receptor 0.0087 0.0091 0.0091
Onchocerca volvulus 0.0282 0.0466 0.2056
Loa Loa (eye worm) hypothetical protein 0.0096 0.0109 0.0389
Schistosoma mansoni cercarial elastase (S01 family) 0.0184 0.0279 0.029
Echinococcus granulosus fibrillin 1 0.0051 0.0024 0.0024
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0626 0.1126 0.1126
Toxoplasma gondii PAN domain-containing protein 0.0179 0.0269 0.075
Schistosoma mansoni adenylate cyclase 0.0096 0.0109 0.0113
Brugia malayi CUB domain containing protein 0.0061 0.0042 0.0152
Echinococcus multilocularis neuropeptide s receptor 0.0626 0.1126 0.1126
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0043 0.0007 0.0026
Echinococcus multilocularis neuropeptide receptor 0.1087 0.2011 0.2011
Echinococcus granulosus retinal guanylyl cyclase 2 0.0046 0.0014 0.0014
Onchocerca volvulus 0.0179 0.0269 0.1187
Schistosoma mansoni voltage-gated potassium channel 0.0519 0.0922 0.0958
Echinococcus granulosus g protein coupled receptor 0.0626 0.1126 0.1126
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0139 0.0192 0.02
Echinococcus multilocularis integrin alpha ps 0.0357 0.0611 0.0611
Echinococcus granulosus tyrosine protein kinase Fyn 0.0043 0.0008 0.0008
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0069 0.0057 0.0205
Echinococcus multilocularis tissue type plasminogen activator 0.0282 0.0466 0.0466
Loa Loa (eye worm) hypothetical protein 0.0186 0.0282 0.101
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Schistosoma mansoni tyrosine kinase 0.005 0.0021 0.0022
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0626 0.1126 0.117
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Brugia malayi hypothetical protein 0.0626 0.1126 0.403
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Echinococcus granulosus adenylate cyclase 9 0.0096 0.0109 0.0109
Brugia malayi ORL1-like opioid receptor 0.0626 0.1126 0.403
Schistosoma mansoni hypothetical protein 0.0626 0.1126 0.117
Schistosoma mansoni hypothetical protein 0.0802 0.1465 0.1521
Schistosoma mansoni hypothetical protein 0.0802 0.1465 0.1521
Echinococcus multilocularis g protein coupled receptor 0.0626 0.1126 0.1126
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0626 0.1126 0.117
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0043 0.0007 0.0007
Echinococcus multilocularis tyrosine protein kinase Srms 0.0039 0.0001 0.0001
Brugia malayi PAN domain containing protein 0.0179 0.0269 0.0963
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.1281 0.2383 0.2476
Echinococcus granulosus tyrosine kinase 0.005 0.0021 0.0021
Brugia malayi PAN domain containing protein 0.0179 0.0269 0.0963
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0126 0.0167 0.0167
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0069 0.0057 0.0205
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0626 0.1126 0.117
Loa Loa (eye worm) hypothetical protein 0.0139 0.0192 0.0688
Loa Loa (eye worm) hypothetical protein 0.0051 0.0024 0.0085
Echinococcus granulosus somatostatin receptor 0.0626 0.1126 0.1126
Schistosoma mansoni amine GPCR 0.0626 0.1126 0.117
Echinococcus granulosus serotonin receptor 0.0626 0.1126 0.1126
Brugia malayi neuropeptide F receptor 0.0626 0.1126 0.403
Loa Loa (eye worm) hypothetical protein 0.0511 0.0907 0.3245
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0043 0.0007 0.0007
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0043 0.0007 0.0026
Echinococcus granulosus nAChR subunit 0.0139 0.0192 0.0192
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0139 0.0192 0.0688
Schistosoma mansoni biogenic amine receptor 0.0626 0.1126 0.117
Echinococcus multilocularis adenylate cyclase 9 0.0096 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0139 0.0192 0.0688
Schistosoma mansoni metabotropic glutamate receptor 0.0043 0.0007 0.0008
Echinococcus multilocularis g-protein coupled receptor 0.0626 0.1126 0.1126
Schistosoma mansoni vesicular amine transporter 0.0045 0.0011 0.0012
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.0031 0.0112
Echinococcus multilocularis protein jagged 2 0.0051 0.0024 0.0024
Schistosoma mansoni cercarial elastase (S01 family) 0.0184 0.0279 0.029
Onchocerca volvulus 0.018 0.027 0.1191
Echinococcus granulosus metabotropic glutamate receptor 5 0.0043 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0051 0.0024 0.0085
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0626 0.1126 0.117
Echinococcus multilocularis somatostatin receptor 0.0626 0.1126 0.1126
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0001 0.0001
Echinococcus granulosus integrin alpha ps 0.0357 0.0611 0.0611
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0626 0.1126 0.1126
Loa Loa (eye worm) hypothetical protein 0.0139 0.0192 0.0688
Onchocerca volvulus 0.0626 0.1126 0.4969
Schistosoma mansoni amine GPCR 0.0626 0.1126 0.117
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0084 0.0087 1
Echinococcus granulosus integrin alpha 3 0.0171 0.0254 0.0254
Onchocerca volvulus 0.1036 0.1913 0.844
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Loa Loa (eye worm) hypothetical protein 0.0139 0.0192 0.0688
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0139 0.0192 0.0192
Brugia malayi Trypsin family protein 0.0184 0.0279 0.0998
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0626 0.1126 0.1126
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0139 0.0192 0.0688
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0046 0.0014 0.0014
Schistosoma mansoni apoptosis regulator bax 0.0802 0.1465 0.1521
Brugia malayi hypothetical protein 0.0626 0.1126 0.403
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0626 0.1126 0.1126
Echinococcus multilocularis tyrosine kinase 0.005 0.0021 0.0021
Loa Loa (eye worm) hypothetical protein 0.0069 0.0057 0.0205
Schistosoma mansoni tyrosine kinase 0.0043 0.0008 0.0008
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0626 0.1126 0.117
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0184 0.0279 0.0279
Loa Loa (eye worm) hypothetical protein 0.0069 0.0057 0.0205
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0048 0.0172
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0139 0.0192 0.0192
Echinococcus granulosus tyrosine protein kinase Blk 0.0039 0.0001 0.0001
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0139 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0069 0.0057 0.0205
Echinococcus granulosus neuropeptide receptor 0.0626 0.1126 0.1126
Plasmodium falciparum cysteine repeat modular protein 1 0.0282 0.0466 1
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0101 0.012 0.012
Giardia lamblia High cysteine protein 0.0051 0.0024 1
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0139 0.0192 0.0688
Onchocerca volvulus 0.0626 0.1126 0.4969
Loa Loa (eye worm) hypothetical protein 0.0069 0.0057 0.0205
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0043 0.0007 0.0007
Onchocerca volvulus 0.0626 0.1126 0.4969
Echinococcus multilocularis neuropeptide Y receptor 0.0626 0.1126 0.1126
Giardia lamblia Neurogenic locus notch-like protein 0.0051 0.0024 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.0626 0.1126 0.1126
Echinococcus multilocularis voltage dependent calcium channel 0.0126 0.0167 0.0167
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0011 0.0012
Schistosoma mansoni biogenic amine receptor 0.0626 0.1126 0.117
Echinococcus multilocularis transmembrane protease serine 3 0.0184 0.0279 0.0279
Loa Loa (eye worm) hypothetical protein 0.007 0.006 0.0216
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0043 0.0007 0.0026
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0043 0.0007 0.0007
Echinococcus granulosus voltage dependent calcium channel 0.0126 0.0167 0.0167
Onchocerca volvulus 0.058 0.1039 0.4582
Loa Loa (eye worm) hypothetical protein 0.0069 0.0057 0.0205
Echinococcus multilocularis potassium voltage gated channel protein 0.0045 0.0011 0.0011
Schistosoma mansoni biogenic amine (5HT) receptor 0.0626 0.1126 0.117
Schistosoma mansoni opsin-like receptor 0.0626 0.1126 0.117
Mycobacterium tuberculosis Possible adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase) 0.0039 0 0.5
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0626 0.1126 0.403
Trichomonas vaginalis hypothetical protein 0.0051 0.0024 1
Echinococcus multilocularis glycoprotein Antigen 5 0.0184 0.0279 0.0279
Echinococcus granulosus dro:myosuppressin receptor 0.0626 0.1126 0.1126
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0626 0.1126 0.1126
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0626 0.1126 0.1126
Echinococcus multilocularis tyrosine protein kinase Blk 0.0039 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0139 0.0192 0.0688
Loa Loa (eye worm) hypothetical protein 0.0802 0.1465 0.5242
Loa Loa (eye worm) glutamate receptor 0.0043 0.0007 0.0026
Echinococcus multilocularis adenylate cyclase type IX 0.0788 0.1437 0.1437
Giardia lamblia Tenascin precursor 0.0051 0.0024 1
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Schistosoma mansoni amine GPCR 0.0626 0.1126 0.117
Onchocerca volvulus 0.0626 0.1126 0.4969
Toxoplasma gondii microneme protein MIC17A 0.0179 0.0269 0.075
Brugia malayi G-protein coupled receptor 0.0626 0.1126 0.403
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Loa Loa (eye worm) hypothetical protein 0.0139 0.0192 0.0688
Schistosoma mansoni acetylcholine receptor subunit beta 0.0069 0.0057 0.0059
Echinococcus granulosus transmembrane protease serine 3 0.0184 0.0279 0.0279
Schistosoma mansoni neuropeptide receptor 0.0626 0.1126 0.117
Loa Loa (eye worm) hypothetical protein 0.0069 0.0057 0.0205
Onchocerca volvulus 0.0139 0.0192 0.0848
Loa Loa (eye worm) hypothetical protein 0.0184 0.0279 0.0998
Loa Loa (eye worm) hypothetical protein 0.0051 0.0024 0.0085
Onchocerca volvulus 0.007 0.006 0.0266
Onchocerca volvulus 0.0179 0.0269 0.1187
Treponema pallidum adenylate cyclase 0.0039 0 0.5
Onchocerca volvulus 0.0069 0.0057 0.0252
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0043 0.0008 0.0008
Schistosoma mansoni serine/threonine RGC 0.0046 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.007 0.006 0.0216
Onchocerca volvulus 0.0179 0.0269 0.1187
Schistosoma mansoni voltage-gated potassium channel 0.0519 0.0922 0.0958
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0011 0.0012
Loa Loa (eye worm) PAN domain-containing protein 0.0179 0.0269 0.0963
Echinococcus granulosus fibrillin 2 0.0051 0.0024 0.0024
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0139 0.0192 0.0192
Onchocerca volvulus 0.0179 0.0269 0.1187
Loa Loa (eye worm) hypothetical protein 0.0069 0.0057 0.0205
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0069 0.0057 0.0205
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0626 0.1126 0.1126
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0046 0.0014 0.0014
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0626 0.1126 0.403
Schistosoma mansoni nAChR subunit 0.0069 0.0057 0.0059
Schistosoma mansoni integrin alpha-4 0.1527 0.2856 0.2966
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0626 0.1126 0.1126
Echinococcus multilocularis fmrfamide receptor 0.0626 0.1126 0.1126
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.018 0.027 0.028
Echinococcus multilocularis 0.0046 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0043 0.0007 0.0026
Schistosoma mansoni cercarial elastase (S01 family) 0.0184 0.0279 0.029
Brugia malayi PAN domain containing protein 0.0179 0.0269 0.0963
Entamoeba histolytica hypothetical protein 0.007 0.006 1
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Toxoplasma gondii PAN domain-containing protein 0.0179 0.0269 0.075
Echinococcus granulosus glutamate receptor 2 0.0043 0.0007 0.0007
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0139 0.0192 0.02
Loa Loa (eye worm) PAN domain-containing protein 0.0179 0.0269 0.0963
Brugia malayi hypothetical protein 0.0069 0.0057 0.0205
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Loa Loa (eye worm) hypothetical protein 0.058 0.1039 0.3717
Loa Loa (eye worm) hypothetical protein 0.007 0.006 0.0216
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0626 0.1126 0.117
Echinococcus multilocularis nmda type glutamate receptor 0.0043 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0043 0.0007 0.0026
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0282 0.0466 1
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0001 0.0001
Schistosoma mansoni neuropeptide receptor 0.0626 0.1126 0.117
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.058 0.1039 0.1079
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0184 0.0279 0.0279
Echinococcus granulosus glycine receptor subunit alpha 1 0.0139 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0126 0.0167 0.0599
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0802 0.1465 0.1521
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0069 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0179 0.0269 0.0963
Onchocerca volvulus 0.0626 0.1126 0.4969
Echinococcus granulosus neuropeptide receptor A26 0.0626 0.1126 0.1126
Trypanosoma cruzi hypothetical protein, conserved 0.0282 0.0466 1
Toxoplasma gondii microneme protein MIC17B 0.0179 0.0269 0.075
Onchocerca volvulus 0.0525 0.0933 0.4118
Trypanosoma cruzi extracellular receptor, putative 0.0043 0.0007 0.0155
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0525 0.0933 0.4118
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0171 0.0254 0.0908
Schistosoma mansoni neuropeptide F-like receptor 0.0626 0.1126 0.117
Brugia malayi Cation transporter family protein 0.058 0.1039 0.3717
Brugia malayi PAN domain containing protein 0.0179 0.0269 0.0963
Schistosoma mansoni hypothetical protein 0.0282 0.0466 0.0484
Brugia malayi EGF-like domain containing protein 0.0051 0.0024 0.0085
Schistosoma mansoni serine-type protease inhibitor 0.5056 0.9627 1
Brugia malayi hypothetical protein 0.0626 0.1126 0.403
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Schistosoma mansoni neuropeptide f receptor 76f 0.0626 0.1126 0.117
Echinococcus granulosus nAChR subunit 0.007 0.006 0.006
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0126 0.0167 0.0167
Echinococcus granulosus glycoprotein Antigen 5 0.0184 0.0279 0.0279
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0043 0.0008 0.0008
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0139 0.0192 0.0192
Echinococcus multilocularis serotonin receptor 0.0626 0.1126 0.1126
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.007 0.006 0.0063
Echinococcus granulosus alpha 1A adrenergic receptor 0.0626 0.1126 0.1126
Echinococcus multilocularis rhodopsin orphan GPCR 0.0626 0.1126 0.1126
Brugia malayi GnHR receptor homolog 0.0626 0.1126 0.403
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0011 0.0012
Loa Loa (eye worm) TK protein kinase 0.0039 0.0001 0.0004
Mycobacterium ulcerans adenylylate/guanylate cyclase 0.0126 0.0168 0.6017
Loa Loa (eye worm) hypothetical protein 0.005 0.0021 0.0075
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Schistosoma mansoni neuropeptide receptor 0.0626 0.1126 0.117
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Schistosoma mansoni adenylate cyclase 0.0096 0.0109 0.0113
Echinococcus granulosus neuropeptide FF receptor 2 0.0626 0.1126 0.1126
Echinococcus granulosus g protein coupled receptor 0.0626 0.1126 0.1126
Toxoplasma gondii microneme protein, putative 0.0179 0.0269 0.075
Echinococcus granulosus tissue type plasminogen activator 0.0282 0.0466 0.0466
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0084 0.0087 0.1872
Loa Loa (eye worm) hypothetical protein 0.0042 0.0006 0.002
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0139 0.0192 0.0688
Schistosoma mansoni alpha-1 adrenergic receptor 0.0626 0.1126 0.117
Schistosoma mansoni neurotransmitter gated ion channel 0.0069 0.0057 0.0059
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Schistosoma mansoni hypothetical protein 0.0171 0.0254 0.0264
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0039 0.0001 0.0001
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0054 0.0029 0.0029
Toxoplasma gondii hypothetical protein 0.0179 0.0269 0.075
Mycobacterium leprae conserved hypothetical protein 0.0039 0 0.5
Schistosoma mansoni histamine h1 receptor 0.0626 0.1126 0.117
Echinococcus multilocularis integrin alpha 3 0.0171 0.0254 0.0254
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0626 0.1126 0.403
Schistosoma mansoni voltage-gated potassium channel 0.0045 0.0011 0.0012
Echinococcus granulosus glutamate receptor 2 0.0043 0.0007 0.0007
Onchocerca volvulus 0.0184 0.0279 0.123
Loa Loa (eye worm) hypothetical protein 0.0043 0.0007 0.0026
Onchocerca volvulus 0.0179 0.0269 0.1187
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0043 0.0007 0.0007
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0212 0.0333 0.0346
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0126 0.0167 0.0174
Schistosoma mansoni hypothetical protein 0.0626 0.1126 0.117
Brugia malayi PAN domain containing protein 0.0179 0.0269 0.0963
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0626 0.1126 0.403
Echinococcus multilocularis integrin beta 2 0.1177 0.2184 0.2184
Onchocerca volvulus 0.0069 0.0057 0.0252
Echinococcus granulosus rhodopsin orphan GPCR 0.0626 0.1126 0.1126
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0184 0.0279 0.0279
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0045 0.0011 0.0011
Onchocerca volvulus 0.018 0.027 0.1191
Onchocerca volvulus 0.0626 0.1126 0.4969
Mycobacterium tuberculosis Possible transcriptional regulatory protein 0.0039 0 0.5
Echinococcus multilocularis g protein coupled receptor 0.0626 0.1126 0.1126
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Giardia lamblia Tenascin-like 0.0051 0.0024 1
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Loa Loa (eye worm) neuropeptide F receptor 0.0626 0.1126 0.403
Schistosoma mansoni cercarial elastase (S01 family) 0.0184 0.0279 0.029
Echinococcus multilocularis glycine receptor subunit beta 0.0139 0.0192 0.0192
Brugia malayi metabotropic glutamate receptor type 2 0.0043 0.0007 0.0026
Echinococcus multilocularis fibrillin 2 0.0051 0.0024 0.0024
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.007 0.006 0.0063
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0043 0.0007 0.0007
Echinococcus granulosus hypothetical protein 0.1459 0.2725 0.2725
Brugia malayi Integrin alpha pat-2 precursor 0.0357 0.0611 0.2185
Echinococcus multilocularis voltage dependent calcium channel 0.0126 0.0167 0.0167
Echinococcus granulosus integrin beta 2 0.1177 0.2184 0.2184
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0139 0.0192 0.0688
Loa Loa (eye worm) RGC/RGC protein kinase 0.0089 0.0096 0.0342
Mycobacterium tuberculosis Possible adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase) 0.0039 0 0.5
Brugia malayi AKH receptor 0.0626 0.1126 0.403
Onchocerca volvulus 0.0179 0.0269 0.1187
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0065 0.005 0.005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0626 0.1126 0.1126
Schistosoma mansoni tyrosine kinase 0.0156 0.0224 0.0233
Loa Loa (eye worm) hypothetical protein 0.0184 0.0279 0.0998
Echinococcus multilocularis rhodopsin orphan GPCR 0.0626 0.1126 0.1126
Loa Loa (eye worm) hypothetical protein 0.122 0.2266 0.8111
Loa Loa (eye worm) hypothetical protein 0.0139 0.0192 0.0688
Echinococcus granulosus neuropeptide Y receptor 0.0626 0.1126 0.1126
Onchocerca volvulus 0.0486 0.0859 0.3788
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0626 0.1126 0.117
Echinococcus multilocularis atrial natriuretic peptide receptor 0.013 0.0175 0.0175
Onchocerca volvulus 0.0051 0.0024 0.0104
Schistosoma mansoni integrin alpha 0.0357 0.0611 0.0634
Loa Loa (eye worm) hypothetical protein 0.0139 0.0192 0.0688
Echinococcus granulosus potassium voltage gated channel protein 0.0045 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0626 0.1126 0.403
Echinococcus multilocularis enteropeptidase 0.0184 0.0279 0.0279

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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