Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0017 | 0.0045 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0071 | 0.0504 | 0.1349 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.0009 | 0.0014 | 0.0163 |
Mycobacterium ulcerans | protoporphyrinogen oxidase | 0.0041 | 0.0264 | 0.0582 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0044 | 0.0295 | 0.0395 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0017 | 0.0022 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0022 | 0.003 |
Schistosoma mansoni | hypothetical protein | 0.0475 | 0.3733 | 1 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0015 | 0.0059 | 0.0218 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.0194 | 0.0519 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0107 | 0.0797 | 0.2134 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0041 | 0.0264 | 0.0627 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0017 | 0.0045 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0017 | 0.0045 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0026 | 0.0147 | 0.1848 |
Loa Loa (eye worm) | ABC transporter | 0.0018 | 0.0085 | 0.1062 |
Schistosoma mansoni | jumonji domain containing protein | 0.0056 | 0.0384 | 0.1027 |
Plasmodium vivax | lysine-specific histone demethylase 1, putative | 0.0041 | 0.0264 | 0.0937 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0007 | 0.0018 |
Echinococcus granulosus | aldo keto reductase family 1, member B4 | 0.0009 | 0.0014 | 0.0037 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.0504 | 0.1109 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0017 | 0.0023 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0058 | 0.0403 | 0.0555 |
Leishmania major | ATP-binding cassette protein subfamily G, member 4, putative | 0.0021 | 0.011 | 0.0411 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.0087 | 0.012 |
Giardia lamblia | Aldose reductase | 0.0032 | 0.0194 | 0.0331 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0023 | 0.0288 |
Plasmodium vivax | ABC transporter G family member 2, putative | 0.0021 | 0.011 | 0.0361 |
Onchocerca volvulus | 0.0032 | 0.0194 | 0.018 | |
Trypanosoma brucei | RNA helicase, putative | 0.0116 | 0.0863 | 0.3211 |
Echinococcus granulosus | hypothetical protein | 0.0032 | 0.0194 | 0.0519 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0071 | 0.0504 | 0.0675 |
Leishmania major | ATP-binding cassette protein subfamily G, member 6, putative | 0.0021 | 0.011 | 0.0411 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0017 | 0.0045 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0017 | 0.0209 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0209 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Echinococcus multilocularis | ATP binding cassette sub family G | 0.0021 | 0.011 | 0.0148 |
Echinococcus multilocularis | aldo keto reductase | 0.0032 | 0.0194 | 0.026 |
Plasmodium vivax | telomerase reverse transcriptase, putative | 0.0344 | 0.2688 | 1 |
Mycobacterium ulcerans | transmembrane ABC transporter ATP-binding protein | 0.0021 | 0.011 | 0.0243 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Echinococcus granulosus | dnaJ subfamily B | 0.0475 | 0.3733 | 1 |
Toxoplasma gondii | histone lysine-specific demethylase | 0.0041 | 0.0264 | 0.0984 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0017 | 0.0022 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0017 | 0.0023 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0017 | 0.0209 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0015 | 0.0059 | 0.0079 |
Loa Loa (eye worm) | oxidoreductase | 0.0032 | 0.0194 | 0.2431 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.0194 | 0.0519 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0071 | 0.0504 | 0.1195 |
Entamoeba histolytica | aldose reductase, putative | 0.0032 | 0.0194 | 0.3339 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Echinococcus multilocularis | ATP binding cassette sub family G | 0.0021 | 0.011 | 0.0148 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0475 | 0.3733 | 0.5005 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0059 | 0.0081 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0257 | 0.0687 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0017 | 0.0045 |
Schistosoma mansoni | ATP-binding cassette sub-family g2 (white protein) (abcg2) | 0.0021 | 0.011 | 0.0296 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0107 | 0.0797 | 0.2964 |
Brugia malayi | ABC transporter family protein | 0.0018 | 0.0085 | 0.0117 |
Echinococcus granulosus | aldo keto reductase | 0.0032 | 0.0194 | 0.0519 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0403 | 0.5055 |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.0009 | 0.0014 | 0.0019 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0017 | 0.0045 |
Echinococcus granulosus | ATP binding cassette sub family G | 0.0021 | 0.011 | 0.0296 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0071 | 0.0504 | 0.1873 |
Schistosoma mansoni | amine oxidase | 0.0041 | 0.0264 | 0.0708 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0087 | 0.0232 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0077 | 0.0553 | 0.0762 |
Chlamydia trachomatis | protoporphyrinogen oxidase | 0.0041 | 0.0264 | 0.5 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0264 | 0.0365 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0032 | 0.0194 | 0.0267 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0015 | 0.0059 | 0.0736 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0107 | 0.0797 | 1 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0107 | 0.0797 | 0.2668 |
Schistosoma mansoni | phd/f-box containing protein | 0.0015 | 0.0059 | 0.0157 |
Toxoplasma gondii | RNA-directed DNA polymerase | 0.0344 | 0.2688 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0009 | 0.0014 | 0.0033 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0058 | 0.0403 | 0.5055 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Trypanosoma brucei | telomerase reverse transcriptase | 0.0344 | 0.2688 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.0194 | 0.0519 |
Brugia malayi | Cytochrome P450 family protein | 0.0026 | 0.0147 | 0.0203 |
Brugia malayi | SWIRM domain containing protein | 0.0041 | 0.0264 | 0.0365 |
Echinococcus multilocularis | aldo keto reductase | 0.0032 | 0.0194 | 0.026 |
Mycobacterium tuberculosis | Probable conserved transmembrane ATP-binding protein ABC transporter | 0.0018 | 0.0083 | 0.0196 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0015 | 0.0059 | 0.0218 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0059 | 0.0081 |
Onchocerca volvulus | 0.0032 | 0.0194 | 0.018 | |
Mycobacterium ulcerans | dehydrogenase | 0.0041 | 0.0264 | 0.0582 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0009 | 0.0014 | 0.0163 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0026 | 0.0147 | 0.1848 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0056 | 0.0384 | 0.0514 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0059 | 0.0081 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0017 | 0.0023 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Echinococcus multilocularis | 0.0041 | 0.0264 | 0.0354 | |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0023 | 0.0061 |
Trypanosoma brucei | aldo/keto reductase, putative | 0.0009 | 0.0014 | 0.0052 |
Plasmodium falciparum | ABC transporter G family member 2 | 0.0021 | 0.011 | 0.0361 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0057 | 0.0399 | 0.1068 |
Echinococcus granulosus | ATP binding cassette sub family G | 0.0021 | 0.011 | 0.0296 |
Entamoeba histolytica | ABC transporter, putative | 0.0021 | 0.011 | 0.1792 |
Onchocerca volvulus | 0.001 | 0.0017 | 0.0003 | |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0041 | 0.0264 | 0.0708 |
Leishmania major | telomerase reverse transcriptase, putative | 0.0344 | 0.2688 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0015 | 0.0059 | 0.0157 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0107 | 0.0797 | 0.2964 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0264 | 0.3318 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0026 | 0.0147 | 0.0548 |
Echinococcus granulosus | GPCR family 2 | 0.0018 | 0.0087 | 0.0232 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0077 | 0.0553 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0107 | 0.0797 | 0.2964 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0017 | 0.0022 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0017 | 0.0045 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0032 | 0.0194 | 0.7328 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.0504 | 0.1109 |
Mycobacterium leprae | PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) | 0.0041 | 0.0264 | 1 |
Echinococcus multilocularis | aldehyde reductase | 0.0023 | 0.012 | 0.0161 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0009 | 0.0014 | 0.0163 |
Trypanosoma cruzi | aldo-keto reductase | 0.0032 | 0.0194 | 0.0721 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.0194 | 0.0519 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0107 | 0.0797 | 0.2964 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0033 | 0.0207 | 0.2596 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0015 | 0.0059 | 0.0079 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0007 | 0.0018 |
Echinococcus granulosus | aldo keto reductase | 0.0032 | 0.0194 | 0.0519 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.0009 | 0.0014 | 0.0174 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0032 | 0.0194 | 0.2423 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Echinococcus multilocularis | GPCR, family 2 | 0.0018 | 0.0087 | 0.0116 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0015 | 0.0059 | 0.0079 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0017 | 0.0045 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0087 | 0.0232 |
Entamoeba histolytica | aldose reductase, putative | 0.0032 | 0.0194 | 0.3339 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0942 | 0.746 | 1 |
Leishmania major | UDP-galactopyranose mutase | 0.0041 | 0.0264 | 0.0984 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0044 | 0.0295 | 0.079 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0023 | 0.012 | 0.4554 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0017 | 0.0045 |
Brugia malayi | Telomerase reverse transcriptase | 0.0916 | 0.7252 | 1 |
Schistosoma mansoni | potassium channel beta | 0.0009 | 0.0014 | 0.0037 |
Echinococcus multilocularis | phd:f box containing protein | 0.0015 | 0.0059 | 0.0079 |
Trypanosoma brucei | ATP-binding cassette protein, putative | 0.0021 | 0.011 | 0.0411 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0032 | 0.0194 | 0.2423 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Brugia malayi | amine oxidase, flavin-containing family protein | 0.0041 | 0.0264 | 0.0365 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0017 | 0.0023 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0077 | 0.0553 | 0.2056 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0017 | 0.0074 | 0.0099 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0032 | 0.0194 | 0.0721 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0007 | 0.0009 |
Loa Loa (eye worm) | oxidoreductase | 0.0032 | 0.0194 | 0.2431 |
Onchocerca volvulus | 0.0033 | 0.0207 | 0.0193 | |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0015 | 0.0059 | 0.0218 |
Onchocerca volvulus | 0.0032 | 0.0194 | 0.018 | |
Brugia malayi | Cytochrome P450 family protein | 0.0026 | 0.0147 | 0.0203 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0344 | 0.2688 | 1 |
Trypanosoma brucei | protein kinase, putative | 0.0107 | 0.0797 | 0.2964 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.0504 | 0.1109 |
Echinococcus multilocularis | protoporphyrinogen oxidase | 0.0041 | 0.0264 | 0.0354 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0057 | 0.0399 | 0.1068 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0017 | 0.0023 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0017 | 0.0045 |
Schistosoma mansoni | Lysine-specific histone demethylase 1 | 0.0041 | 0.0264 | 0.0708 |
Mycobacterium ulcerans | transmembrane ABC transporter ATP-binding protein | 0.0021 | 0.011 | 0.0243 |
Echinococcus granulosus | aldehyde reductase | 0.0023 | 0.012 | 0.0322 |
Plasmodium vivax | JmjC domain containing protein | 0.0015 | 0.0059 | 0.0167 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0087 | 0.0232 |
Leishmania major | aldo-keto reductase-like protein | 0.0032 | 0.0194 | 0.0721 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0107 | 0.0797 | 0.2134 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0071 | 0.0504 | 0.1349 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0077 | 0.0553 | 0.2056 |
Schistosoma mansoni | aldo-keto reductase | 0.0032 | 0.0194 | 0.0519 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0041 | 0.0264 | 0.0627 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0264 | 0.3318 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0056 | 0.0384 | 0.1027 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0032 | 0.0194 | 0.0267 |
Schistosoma mansoni | jumonji domain containing protein | 0.0015 | 0.0059 | 0.0157 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0058 | 0.0403 | 0.0555 |
Schistosoma mansoni | Protoporphyrinogen oxidase chloroplast/mitochondrial precursor | 0.0041 | 0.0264 | 0.0708 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0056 | 0.0384 | 0.0514 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0077 | 0.0553 | 0.6936 |
Echinococcus multilocularis | ATP binding cassette sub family G | 0.0021 | 0.011 | 0.0148 |
Toxoplasma gondii | histone lysine-specific demethylase LSD1/BHC110/KDMA1A | 0.0043 | 0.0281 | 0.1044 |
Echinococcus granulosus | ATP binding cassette sub family G | 0.0021 | 0.011 | 0.0296 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0209 |
Plasmodium vivax | hypothetical protein, conserved | 0.0041 | 0.0264 | 0.0937 |
Trypanosoma brucei | cytochrome P450, putative | 0.0026 | 0.0147 | 0.0548 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0017 | 0.0023 |
Echinococcus granulosus | cpg binding protein | 0.0035 | 0.0222 | 0.0595 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0007 | 0.0018 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.0222 | 0.0595 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0015 | 0.0059 | 0.0218 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0194 | 0.2431 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0107 | 0.0797 | 0.2964 |
Leishmania major | hypothetical protein, conserved | 0.0015 | 0.0059 | 0.0218 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.0017 | 0.0003 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0015 | 0.0059 | 0.0157 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0017 | 0.0023 |
Leishmania major | cytochrome p450-like protein | 0.0026 | 0.0147 | 0.0548 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0017 | 0.0023 |
Schistosoma mansoni | ABC transporter | 0.0018 | 0.0085 | 0.0227 |
Brugia malayi | jmjC domain containing protein | 0.0057 | 0.0399 | 0.055 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0017 | 0.0209 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.0194 | 0.0519 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0087 | 0.1089 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0017 | 0.0209 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0032 | 0.0194 | 0.0721 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0087 | 0.0116 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0023 | 0.0031 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0015 | 0.0059 | 0.0157 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0015 | 0.0059 | 0.0736 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0017 | 0.0023 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0077 | 0.0553 | 0.2056 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0015 | 0.0059 | 0.0167 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.0087 | 0.1089 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.0194 | 0.0519 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0059 | 0.0736 |
Brugia malayi | NADH-dependent xylose reductase | 0.0009 | 0.0014 | 0.0019 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.0017 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0264 | 0.3318 |
Brugia malayi | jmjC domain containing protein | 0.0056 | 0.0384 | 0.0529 |
Mycobacterium ulcerans | monoamine oxidase | 0.0041 | 0.0264 | 0.0582 |
Leishmania major | prostaglandin f synthase, putative | 0.0032 | 0.0194 | 0.0721 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0077 | 0.0553 | 0.2056 |
Entamoeba histolytica | aldose reductase, putative | 0.0032 | 0.0194 | 0.3339 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0017 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0209 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0041 | 0.0264 | 0.0937 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0017 | 0.0045 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0017 | 0.0023 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0576 | 0.4539 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0017 | 0.0045 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0017 | 0.0045 |
Mycobacterium leprae | Possible oxidoreductase | 0.0009 | 0.0014 | 0.0525 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0017 | 0.0022 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0107 | 0.0797 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0087 | 0.0116 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0017 | 0.0023 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0017 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0264 | 0.3318 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0017 | 0.0023 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0057 | 0.0399 | 0.5004 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0032 | 0.0194 | 0.0267 |
Toxoplasma gondii | aldo-keto reductase | 0.0009 | 0.0014 | 0.0052 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.0194 | 0.0519 |
Echinococcus granulosus | voltage gated potassium channel subunit | 0.0009 | 0.0014 | 0.0037 |
Echinococcus multilocularis | voltage gated potassium channel subunit | 0.0009 | 0.0014 | 0.0019 |
Echinococcus multilocularis | aldo keto reductase | 0.0032 | 0.0194 | 0.026 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.0017 | 0.0003 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0009 | 0.0014 | 0.0052 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0017 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0209 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0107 | 0.0797 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0017 | 0.0045 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0026 | 0.0147 | 0.1848 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.0194 | 0.0519 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0083 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0209 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0087 | 0.0232 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0107 | 0.0797 | 0.1068 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0207 | 0.0554 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0059 | 0.0081 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0344 | 0.2688 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0017 | 0.0045 |
Plasmodium falciparum | protoporphyrinogen oxidase | 0.0041 | 0.0264 | 0.0937 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0071 | 0.0505 | 0.1354 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0264 | 0.3318 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0077 | 0.0553 | 0.148 |
Plasmodium falciparum | telomerase reverse transcriptase | 0.0344 | 0.2688 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0017 | 0.0045 |
Onchocerca volvulus | 0.0032 | 0.0194 | 0.018 | |
Echinococcus multilocularis | aldo keto reductase | 0.0032 | 0.0194 | 0.026 |
Trypanosoma cruzi | ATP-binding cassette protein, putative | 0.0021 | 0.011 | 0.0411 |
Echinococcus multilocularis | lysine specific histone demethylase 1A | 0.0041 | 0.0264 | 0.0354 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0041 | 0.0264 | 0.0984 |
Toxoplasma gondii | aldo/keto reductase family oxidoreductase | 0.0009 | 0.0014 | 0.0052 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0017 | 0.0022 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Toxoplasma gondii | oxidoreductase, aldo/keto reductase family protein | 0.0009 | 0.0014 | 0.0052 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Schistosoma mansoni | aldo-keto reductase | 0.0032 | 0.0194 | 0.0519 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0017 | 0.0074 | 0.0198 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0017 | 0.0022 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0015 | 0.0059 | 0.0157 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0032 | 0.0194 | 0.2423 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.004 | 0.0257 | 0.0354 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Giardia lamblia | Aldose reductase | 0.0032 | 0.0194 | 0.0331 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0017 | 0.0022 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0032 | 0.0194 | 0.046 |
Schistosoma mansoni | protein phosphatase 2C | 0.0015 | 0.0059 | 0.0157 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0017 | 0.0045 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0107 | 0.0797 | 0.2134 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0041 | 0.0264 | 0.0984 |
Plasmodium vivax | protoporphyrinogen oxidase, putative | 0.0041 | 0.0264 | 0.0937 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0088 | 0.1101 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0059 | 0.0736 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Onchocerca volvulus | 0.0041 | 0.0264 | 0.0251 | |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0017 | 0.0023 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.0222 | 0.0595 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0017 | 0.0023 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0077 | 0.0553 | 0.148 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0015 | 0.0059 | 0.0157 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0041 | 0.0264 | 0.0708 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0209 |
Loa Loa (eye worm) | oxidoreductase | 0.0032 | 0.0194 | 0.2431 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0063 | 0.0445 | 0.1656 |
Loa Loa (eye worm) | oxidoreductase | 0.0032 | 0.0194 | 0.2431 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0017 | 0.0023 |
Mycobacterium ulcerans | oxidoreductase | 0.0032 | 0.0194 | 0.0427 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0264 | 0.3318 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0107 | 0.0797 | 0.2964 |
Echinococcus granulosus | phd:f box containing protein | 0.0015 | 0.0059 | 0.0157 |
Plasmodium vivax | hypothetical protein, conserved | 0.0041 | 0.0264 | 0.0937 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0107 | 0.0797 | 0.2964 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0077 | 0.0553 | 0.0741 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0017 | 0.0023 |
Leishmania major | aldo/keto reductase, putative,aldo/keto reductase family-like protein | 0.0009 | 0.0014 | 0.0052 |
Mycobacterium ulcerans | oxidoreductase | 0.0041 | 0.0264 | 0.0582 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0107 | 0.0797 | 0.1068 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0087 | 0.0232 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0576 | 0.4539 | 1 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0536 | 0.4215 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0017 | 0.0023 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0015 | 0.0059 | 0.0736 |
Schistosoma mansoni | pol-related | 0.0032 | 0.0194 | 0.0519 |
Onchocerca volvulus | 0.0032 | 0.0194 | 0.018 | |
Trypanosoma cruzi | ABC transporter, putative | 0.0021 | 0.011 | 0.0411 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.0194 | 0.0519 |
Brugia malayi | MAP kinase sur-1 | 0.0107 | 0.0797 | 0.1099 |
Giardia lamblia | Telomerase catalytic subunit | 0.0344 | 0.2688 | 1 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0017 | 0.0023 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0026 | 0.0147 | 0.0548 |
Echinococcus multilocularis | cpg binding protein | 0.0035 | 0.0222 | 0.0298 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0071 | 0.0504 | 0.1349 |
Onchocerca volvulus | 0.0032 | 0.0194 | 0.018 | |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0015 | 0.0059 | 0.0218 |
Trypanosoma brucei | ABC transporter, putative | 0.0021 | 0.011 | 0.0411 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0209 |
Plasmodium falciparum | lysine-specific histone demethylase 1, putative | 0.0041 | 0.0264 | 0.0937 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0087 | 0.0232 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0017 | 0.0209 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0057 | 0.0399 | 0.1068 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0107 | 0.0797 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.0087 | 0.012 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0017 | 0.0045 |
Mycobacterium ulcerans | hypothetical protein | 0.0009 | 0.0014 | 0.0031 |
Trypanosoma brucei | prostaglandin f synthase | 0.0032 | 0.0194 | 0.0721 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0032 | 0.0194 | 0.0267 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0017 | 0.0209 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0032 | 0.0194 | 0.0721 |
Schistosoma mansoni | hypothetical protein | 0.0116 | 0.0863 | 0.2312 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0071 | 0.0504 | 0.1873 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0257 | 0.3219 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0017 | 0.0022 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0026 | 0.0147 | 0.0324 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0017 | 0.0023 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0017 | 0.0045 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0009 | 0.0014 | 0.0163 |
Echinococcus granulosus | aldo keto reductase | 0.0032 | 0.0194 | 0.0519 |
Toxoplasma gondii | aldose reductase, putative | 0.0032 | 0.0194 | 0.0721 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0017 | 0.0023 |
Schistosoma mansoni | amine oxidase | 0.0041 | 0.0264 | 0.0708 |
Loa Loa (eye worm) | oxidoreductase | 0.0032 | 0.0194 | 0.2431 |
Mycobacterium ulcerans | transmembrane ABC transporter ATP-binding protein | 0.0021 | 0.011 | 0.0243 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0009 | 0.0014 | 0.0163 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0209 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0107 | 0.0797 | 1 |
Toxoplasma gondii | ATP-binding cassette G family transporter ABCG84 | 0.0021 | 0.011 | 0.0411 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0007 | 0.0009 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0017 | 0.0209 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0059 | 0.0736 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0017 | 0.0209 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.0721 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0017 | 0.0022 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0107 | 0.0797 | 0.2964 |
Brugia malayi | CXXC zinc finger family protein | 0.0033 | 0.0207 | 0.0285 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | Reactivation of VX-inhibited Electrophorus electricus (electric eel) acetylcholinesterase using acetylthiocholine iodide as substrate at 1 mM incubated at 15 min post VX-inhibition measured after 40 min by Ellman method | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.