Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0087 | 0.0232 |
Plasmodium falciparum | lysine-specific histone demethylase 1, putative | 0.0041 | 0.0264 | 0.0937 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0017 | 0.0209 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0057 | 0.0399 | 0.1068 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0107 | 0.0797 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0071 | 0.0504 | 0.1349 |
Trypanosoma brucei | ABC transporter, putative | 0.0021 | 0.011 | 0.0411 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0015 | 0.0059 | 0.0218 |
Onchocerca volvulus | 0.0032 | 0.0194 | 0.018 | |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0209 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0071 | 0.0504 | 0.1873 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0032 | 0.0194 | 0.0721 |
Schistosoma mansoni | hypothetical protein | 0.0116 | 0.0863 | 0.2312 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0026 | 0.0147 | 0.0324 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0257 | 0.3219 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0017 | 0.0022 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Mycobacterium ulcerans | hypothetical protein | 0.0009 | 0.0014 | 0.0031 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0017 | 0.0045 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.0087 | 0.012 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0032 | 0.0194 | 0.0267 |
Trypanosoma brucei | prostaglandin f synthase | 0.0032 | 0.0194 | 0.0721 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0017 | 0.0209 |
Echinococcus granulosus | aldo keto reductase | 0.0032 | 0.0194 | 0.0519 |
Toxoplasma gondii | aldose reductase, putative | 0.0032 | 0.0194 | 0.0721 |
Schistosoma mansoni | amine oxidase | 0.0041 | 0.0264 | 0.0708 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0017 | 0.0023 |
Loa Loa (eye worm) | oxidoreductase | 0.0032 | 0.0194 | 0.2431 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0017 | 0.0023 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0009 | 0.0014 | 0.0163 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0017 | 0.0045 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.0721 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0017 | 0.0022 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0017 | 0.0209 |
Brugia malayi | CXXC zinc finger family protein | 0.0033 | 0.0207 | 0.0285 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0107 | 0.0797 | 0.2964 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0009 | 0.0014 | 0.0163 |
Mycobacterium ulcerans | transmembrane ABC transporter ATP-binding protein | 0.0021 | 0.011 | 0.0243 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0107 | 0.0797 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0209 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0007 | 0.0009 |
Toxoplasma gondii | ATP-binding cassette G family transporter ABCG84 | 0.0021 | 0.011 | 0.0411 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0059 | 0.0736 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0017 | 0.0209 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0041 | 0.0264 | 0.0984 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0088 | 0.1101 |
Plasmodium vivax | protoporphyrinogen oxidase, putative | 0.0041 | 0.0264 | 0.0937 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0059 | 0.0736 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Giardia lamblia | Aldose reductase | 0.0032 | 0.0194 | 0.0331 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0032 | 0.0194 | 0.046 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0017 | 0.0022 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0017 | 0.0045 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0107 | 0.0797 | 0.2134 |
Schistosoma mansoni | protein phosphatase 2C | 0.0015 | 0.0059 | 0.0157 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0077 | 0.0553 | 0.148 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0209 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0041 | 0.0264 | 0.0708 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0015 | 0.0059 | 0.0157 |
Loa Loa (eye worm) | oxidoreductase | 0.0032 | 0.0194 | 0.2431 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0063 | 0.0445 | 0.1656 |
Loa Loa (eye worm) | oxidoreductase | 0.0032 | 0.0194 | 0.2431 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Onchocerca volvulus | 0.0041 | 0.0264 | 0.0251 | |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0017 | 0.0023 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0017 | 0.0023 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.0222 | 0.0595 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0576 | 0.4539 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0087 | 0.0232 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0536 | 0.4215 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0017 | 0.0023 |
Mycobacterium ulcerans | oxidoreductase | 0.0032 | 0.0194 | 0.0427 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0264 | 0.3318 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0017 | 0.0023 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0107 | 0.0797 | 0.2964 |
Echinococcus granulosus | phd:f box containing protein | 0.0015 | 0.0059 | 0.0157 |
Plasmodium vivax | hypothetical protein, conserved | 0.0041 | 0.0264 | 0.0937 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0077 | 0.0553 | 0.0741 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0107 | 0.0797 | 0.2964 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0017 | 0.0023 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0107 | 0.0797 | 0.1068 |
Mycobacterium ulcerans | oxidoreductase | 0.0041 | 0.0264 | 0.0582 |
Leishmania major | aldo/keto reductase, putative,aldo/keto reductase family-like protein | 0.0009 | 0.0014 | 0.0052 |
Giardia lamblia | Telomerase catalytic subunit | 0.0344 | 0.2688 | 1 |
Echinococcus multilocularis | cpg binding protein | 0.0035 | 0.0222 | 0.0298 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0026 | 0.0147 | 0.0548 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0017 | 0.0023 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0015 | 0.0059 | 0.0736 |
Schistosoma mansoni | pol-related | 0.0032 | 0.0194 | 0.0519 |
Onchocerca volvulus | 0.0032 | 0.0194 | 0.018 | |
Trypanosoma cruzi | ABC transporter, putative | 0.0021 | 0.011 | 0.0411 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.0194 | 0.0519 |
Brugia malayi | MAP kinase sur-1 | 0.0107 | 0.0797 | 0.1099 |
Toxoplasma gondii | aldo-keto reductase | 0.0009 | 0.0014 | 0.0052 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.0194 | 0.0519 |
Echinococcus granulosus | voltage gated potassium channel subunit | 0.0009 | 0.0014 | 0.0037 |
Echinococcus multilocularis | aldo keto reductase | 0.0032 | 0.0194 | 0.026 |
Echinococcus multilocularis | voltage gated potassium channel subunit | 0.0009 | 0.0014 | 0.0019 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0017 | 0.0045 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0017 | 0.0023 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0017 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0264 | 0.3318 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0032 | 0.0194 | 0.0267 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0057 | 0.0399 | 0.5004 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0059 | 0.0081 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0207 | 0.0554 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0087 | 0.0232 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0107 | 0.0797 | 0.1068 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0017 | 0.0045 |
Plasmodium falciparum | protoporphyrinogen oxidase | 0.0041 | 0.0264 | 0.0937 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0344 | 0.2688 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0071 | 0.0505 | 0.1354 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0264 | 0.3318 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0077 | 0.0553 | 0.148 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0009 | 0.0014 | 0.0052 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.0017 | 0.0003 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0017 | 0.0045 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0107 | 0.0797 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0209 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0017 | 0.0045 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0026 | 0.0147 | 0.1848 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0209 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0083 | 0.0221 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.0194 | 0.0519 |
Toxoplasma gondii | aldo/keto reductase family oxidoreductase | 0.0009 | 0.0014 | 0.0052 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0017 | 0.0022 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0017 | 0.0045 |
Plasmodium falciparum | telomerase reverse transcriptase | 0.0344 | 0.2688 | 1 |
Onchocerca volvulus | 0.0032 | 0.0194 | 0.018 | |
Trypanosoma cruzi | ATP-binding cassette protein, putative | 0.0021 | 0.011 | 0.0411 |
Echinococcus multilocularis | aldo keto reductase | 0.0032 | 0.0194 | 0.026 |
Echinococcus multilocularis | lysine specific histone demethylase 1A | 0.0041 | 0.0264 | 0.0354 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0041 | 0.0264 | 0.0984 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0017 | 0.0022 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0015 | 0.0059 | 0.0157 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.004 | 0.0257 | 0.0354 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0032 | 0.0194 | 0.2423 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Toxoplasma gondii | oxidoreductase, aldo/keto reductase family protein | 0.0009 | 0.0014 | 0.0052 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0017 | 0.0074 | 0.0198 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Schistosoma mansoni | aldo-keto reductase | 0.0032 | 0.0194 | 0.0519 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0032 | 0.0194 | 0.0721 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0087 | 0.0116 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0023 | 0.0031 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0015 | 0.0059 | 0.0157 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.0194 | 0.0519 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0087 | 0.1089 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0017 | 0.0209 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0264 | 0.3318 |
Brugia malayi | NADH-dependent xylose reductase | 0.0009 | 0.0014 | 0.0019 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.0017 | 0.0003 |
Leishmania major | prostaglandin f synthase, putative | 0.0032 | 0.0194 | 0.0721 |
Brugia malayi | jmjC domain containing protein | 0.0056 | 0.0384 | 0.0529 |
Mycobacterium ulcerans | monoamine oxidase | 0.0041 | 0.0264 | 0.0582 |
Entamoeba histolytica | aldose reductase, putative | 0.0032 | 0.0194 | 0.3339 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0077 | 0.0553 | 0.2056 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0017 | 0.0045 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0015 | 0.0059 | 0.0167 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0015 | 0.0059 | 0.0736 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0017 | 0.0023 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0077 | 0.0553 | 0.2056 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.0087 | 0.1089 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.0194 | 0.0519 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0059 | 0.0736 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0017 | 0.0023 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0576 | 0.4539 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0017 | 0.0045 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0017 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0209 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0041 | 0.0264 | 0.0937 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0017 | 0.0045 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0017 | 0.0022 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0107 | 0.0797 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0087 | 0.0116 |
Mycobacterium leprae | Possible oxidoreductase | 0.0009 | 0.0014 | 0.0525 |
Trypanosoma brucei | protein kinase, putative | 0.0107 | 0.0797 | 0.2964 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0344 | 0.2688 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.0504 | 0.1109 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0057 | 0.0399 | 0.1068 |
Echinococcus multilocularis | protoporphyrinogen oxidase | 0.0041 | 0.0264 | 0.0354 |
Brugia malayi | amine oxidase, flavin-containing family protein | 0.0041 | 0.0264 | 0.0365 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0077 | 0.0553 | 0.2056 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0017 | 0.0023 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0007 | 0.0009 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0017 | 0.0074 | 0.0099 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0032 | 0.0194 | 0.0721 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0015 | 0.0059 | 0.0218 |
Loa Loa (eye worm) | oxidoreductase | 0.0032 | 0.0194 | 0.2431 |
Onchocerca volvulus | 0.0033 | 0.0207 | 0.0193 | |
Onchocerca volvulus | 0.0032 | 0.0194 | 0.018 | |
Brugia malayi | Cytochrome P450 family protein | 0.0026 | 0.0147 | 0.0203 |
Echinococcus granulosus | aldehyde reductase | 0.0023 | 0.012 | 0.0322 |
Mycobacterium ulcerans | transmembrane ABC transporter ATP-binding protein | 0.0021 | 0.011 | 0.0243 |
Plasmodium vivax | JmjC domain containing protein | 0.0015 | 0.0059 | 0.0167 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0017 | 0.0023 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Schistosoma mansoni | Lysine-specific histone demethylase 1 | 0.0041 | 0.0264 | 0.0708 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0017 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0264 | 0.3318 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0056 | 0.0384 | 0.1027 |
Schistosoma mansoni | jumonji domain containing protein | 0.0015 | 0.0059 | 0.0157 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0058 | 0.0403 | 0.0555 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0032 | 0.0194 | 0.0267 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0077 | 0.0553 | 0.6936 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0056 | 0.0384 | 0.0514 |
Schistosoma mansoni | Protoporphyrinogen oxidase chloroplast/mitochondrial precursor | 0.0041 | 0.0264 | 0.0708 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0071 | 0.0504 | 0.1349 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0087 | 0.0232 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0107 | 0.0797 | 0.2134 |
Leishmania major | aldo-keto reductase-like protein | 0.0032 | 0.0194 | 0.0721 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0077 | 0.0553 | 0.2056 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0041 | 0.0264 | 0.0627 |
Schistosoma mansoni | aldo-keto reductase | 0.0032 | 0.0194 | 0.0519 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.0017 | 0.0003 |
Leishmania major | hypothetical protein, conserved | 0.0015 | 0.0059 | 0.0218 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0107 | 0.0797 | 0.2964 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0194 | 0.2431 |
Leishmania major | cytochrome p450-like protein | 0.0026 | 0.0147 | 0.0548 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0015 | 0.0059 | 0.0157 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0017 | 0.0023 |
Schistosoma mansoni | ABC transporter | 0.0018 | 0.0085 | 0.0227 |
Brugia malayi | jmjC domain containing protein | 0.0057 | 0.0399 | 0.055 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0017 | 0.0023 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0017 | 0.0209 |
Echinococcus multilocularis | ATP binding cassette sub family G | 0.0021 | 0.011 | 0.0148 |
Toxoplasma gondii | histone lysine-specific demethylase LSD1/BHC110/KDMA1A | 0.0043 | 0.0281 | 0.1044 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0209 |
Plasmodium vivax | hypothetical protein, conserved | 0.0041 | 0.0264 | 0.0937 |
Echinococcus granulosus | ATP binding cassette sub family G | 0.0021 | 0.011 | 0.0296 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0017 | 0.0023 |
Trypanosoma brucei | cytochrome P450, putative | 0.0026 | 0.0147 | 0.0548 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0007 | 0.0018 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0015 | 0.0059 | 0.0218 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.0222 | 0.0595 |
Echinococcus granulosus | cpg binding protein | 0.0035 | 0.0222 | 0.0595 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.0504 | 0.1109 |
Mycobacterium leprae | PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) | 0.0041 | 0.0264 | 1 |
Echinococcus multilocularis | aldehyde reductase | 0.0023 | 0.012 | 0.0161 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0009 | 0.0014 | 0.0163 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0107 | 0.0797 | 0.2964 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0017 | 0.0022 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0017 | 0.0045 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0032 | 0.0194 | 0.7328 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0033 | 0.0207 | 0.2596 |
Trypanosoma cruzi | aldo-keto reductase | 0.0032 | 0.0194 | 0.0721 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.0194 | 0.0519 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0107 | 0.0797 | 0.2964 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0017 | 0.0045 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0018 | 0.0087 | 0.0232 |
Entamoeba histolytica | aldose reductase, putative | 0.0032 | 0.0194 | 0.3339 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0015 | 0.0059 | 0.0079 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0007 | 0.0018 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Echinococcus granulosus | aldo keto reductase | 0.0032 | 0.0194 | 0.0519 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0032 | 0.0194 | 0.2423 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.0009 | 0.0014 | 0.0174 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0015 | 0.0059 | 0.0079 |
Echinococcus multilocularis | GPCR, family 2 | 0.0018 | 0.0087 | 0.0116 |
Trypanosoma brucei | ATP-binding cassette protein, putative | 0.0021 | 0.011 | 0.0411 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0032 | 0.0194 | 0.2423 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0044 | 0.0295 | 0.079 |
Leishmania major | UDP-galactopyranose mutase | 0.0041 | 0.0264 | 0.0984 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0942 | 0.746 | 1 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0023 | 0.012 | 0.4554 |
Echinococcus multilocularis | phd:f box containing protein | 0.0015 | 0.0059 | 0.0079 |
Brugia malayi | Telomerase reverse transcriptase | 0.0916 | 0.7252 | 1 |
Schistosoma mansoni | potassium channel beta | 0.0009 | 0.0014 | 0.0037 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0017 | 0.0045 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0107 | 0.0797 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0015 | 0.0059 | 0.0736 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0107 | 0.0797 | 0.2668 |
Schistosoma mansoni | phd/f-box containing protein | 0.0015 | 0.0059 | 0.0157 |
Toxoplasma gondii | RNA-directed DNA polymerase | 0.0344 | 0.2688 | 1 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0077 | 0.0553 | 0.0762 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0071 | 0.0504 | 0.1873 |
Echinococcus granulosus | ATP binding cassette sub family G | 0.0021 | 0.011 | 0.0296 |
Schistosoma mansoni | amine oxidase | 0.0041 | 0.0264 | 0.0708 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0018 | 0.0087 | 0.0232 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0017 | 0.0045 |
Chlamydia trachomatis | protoporphyrinogen oxidase | 0.0041 | 0.0264 | 0.5 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0264 | 0.0365 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0032 | 0.0194 | 0.0267 |
Brugia malayi | SWIRM domain containing protein | 0.0041 | 0.0264 | 0.0365 |
Mycobacterium tuberculosis | Probable conserved transmembrane ATP-binding protein ABC transporter | 0.0018 | 0.0083 | 0.0196 |
Echinococcus multilocularis | aldo keto reductase | 0.0032 | 0.0194 | 0.026 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0015 | 0.0059 | 0.0218 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0058 | 0.0403 | 0.5055 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Mycobacterium tuberculosis | Conserved protein | 0.0009 | 0.0014 | 0.0033 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.0194 | 0.0519 |
Trypanosoma brucei | telomerase reverse transcriptase | 0.0344 | 0.2688 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0026 | 0.0147 | 0.0203 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0023 | 0.0061 |
Trypanosoma brucei | aldo/keto reductase, putative | 0.0009 | 0.0014 | 0.0052 |
Echinococcus multilocularis | 0.0041 | 0.0264 | 0.0354 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Echinococcus granulosus | ATP binding cassette sub family G | 0.0021 | 0.011 | 0.0296 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0057 | 0.0399 | 0.1068 |
Plasmodium falciparum | ABC transporter G family member 2 | 0.0021 | 0.011 | 0.0361 |
Entamoeba histolytica | ABC transporter, putative | 0.0021 | 0.011 | 0.1792 |
Onchocerca volvulus | 0.001 | 0.0017 | 0.0003 | |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0059 | 0.0081 |
Onchocerca volvulus | 0.0032 | 0.0194 | 0.018 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0009 | 0.0014 | 0.0163 |
Mycobacterium ulcerans | dehydrogenase | 0.0041 | 0.0264 | 0.0582 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0059 | 0.0081 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0056 | 0.0384 | 0.0514 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0026 | 0.0147 | 0.1848 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0017 | 0.0023 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0077 | 0.0553 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0018 | 0.0087 | 0.0232 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0041 | 0.0264 | 0.0708 |
Leishmania major | telomerase reverse transcriptase, putative | 0.0344 | 0.2688 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0015 | 0.0059 | 0.0157 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0264 | 0.3318 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0026 | 0.0147 | 0.0548 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0107 | 0.0797 | 0.2964 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0107 | 0.0797 | 0.2134 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.0194 | 0.0519 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0017 | 0.0045 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0017 | 0.0045 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0041 | 0.0264 | 0.0627 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0026 | 0.0147 | 0.1848 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0071 | 0.0504 | 0.1349 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0017 | 0.0045 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0017 | 0.0022 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0044 | 0.0295 | 0.0395 |
Mycobacterium ulcerans | protoporphyrinogen oxidase | 0.0041 | 0.0264 | 0.0582 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.0009 | 0.0014 | 0.0163 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0022 | 0.003 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0015 | 0.0059 | 0.0218 |
Schistosoma mansoni | hypothetical protein | 0.0475 | 0.3733 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0058 | 0.0403 | 0.0555 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0017 | 0.0023 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.0087 | 0.012 |
Giardia lamblia | Aldose reductase | 0.0032 | 0.0194 | 0.0331 |
Leishmania major | ATP-binding cassette protein subfamily G, member 4, putative | 0.0021 | 0.011 | 0.0411 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0023 | 0.0288 |
Onchocerca volvulus | 0.0032 | 0.0194 | 0.018 | |
Plasmodium vivax | ABC transporter G family member 2, putative | 0.0021 | 0.011 | 0.0361 |
Echinococcus granulosus | hypothetical protein | 0.0032 | 0.0194 | 0.0519 |
Trypanosoma brucei | RNA helicase, putative | 0.0116 | 0.0863 | 0.3211 |
Schistosoma mansoni | jumonji domain containing protein | 0.0056 | 0.0384 | 0.1027 |
Loa Loa (eye worm) | ABC transporter | 0.0018 | 0.0085 | 0.1062 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0007 | 0.0018 |
Plasmodium vivax | lysine-specific histone demethylase 1, putative | 0.0041 | 0.0264 | 0.0937 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0071 | 0.0504 | 0.1109 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Echinococcus granulosus | aldo keto reductase family 1, member B4 | 0.0009 | 0.0014 | 0.0037 |
Toxoplasma gondii | histone lysine-specific demethylase | 0.0041 | 0.0264 | 0.0984 |
Echinococcus granulosus | dnaJ subfamily B | 0.0475 | 0.3733 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0032 | 0.0194 | 0.026 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0017 | 0.0022 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0017 | 0.0209 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0017 | 0.0023 |
Loa Loa (eye worm) | oxidoreductase | 0.0032 | 0.0194 | 0.2431 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0015 | 0.0059 | 0.0079 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0071 | 0.0504 | 0.0675 |
Leishmania major | ATP-binding cassette protein subfamily G, member 6, putative | 0.0021 | 0.011 | 0.0411 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0017 | 0.0045 |
Echinococcus multilocularis | ATP binding cassette sub family G | 0.0021 | 0.011 | 0.0148 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0017 | 0.0209 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0017 | 0.0209 |
Mycobacterium ulcerans | transmembrane ABC transporter ATP-binding protein | 0.0021 | 0.011 | 0.0243 |
Plasmodium vivax | telomerase reverse transcriptase, putative | 0.0344 | 0.2688 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0032 | 0.0194 | 0.026 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0017 | 0.0045 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0257 | 0.0687 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0059 | 0.0081 |
Schistosoma mansoni | ATP-binding cassette sub-family g2 (white protein) (abcg2) | 0.0021 | 0.011 | 0.0296 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0107 | 0.0797 | 0.2964 |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.0009 | 0.0014 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0403 | 0.5055 |
Echinococcus granulosus | aldo keto reductase | 0.0032 | 0.0194 | 0.0519 |
Brugia malayi | ABC transporter family protein | 0.0018 | 0.0085 | 0.0117 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0032 | 0.0194 | 0.0519 |
Entamoeba histolytica | aldose reductase, putative | 0.0032 | 0.0194 | 0.3339 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0071 | 0.0504 | 0.1195 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0032 | 0.0194 | 0.2423 |
Echinococcus multilocularis | ATP binding cassette sub family G | 0.0021 | 0.011 | 0.0148 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0475 | 0.3733 | 0.5005 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | Reactivation of VX-inhibited Electrophorus electricus (electric eel) acetylcholinesterase using acetylthiocholine iodide as substrate at 1 mM incubated at 15 min post VX-inhibition measured after 40 min by Ellman method | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.