Detailed information for compound 1810803

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 244.284 | Formula: C12H20O5
  • H donors: 3 H acceptors: 4 LogP: 0.6 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC[C@H]1OC(=O)[C@@H](O)CC/C=C/[C@@H]([C@@H]1O)O
  • InChi: 1S/C12H20O5/c1-2-5-10-11(15)8(13)6-3-4-7-9(14)12(16)17-10/h3,6,8-11,13-15H,2,4-5,7H2,1H3/b6-3+/t8-,9-,10+,11-/m0/s1
  • InChiKey: KQJGPGHQDDZVHJ-JMRRKZTASA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum glutamyl-tRNA(Gln) amidotransferase subunit A 0.0026 0.0123 0.0659
Trypanosoma cruzi glycerol uptake protein, putative 0.0049 0.0419 0.2467
Echinococcus multilocularis sterol O acyltransferase 1 0.0049 0.0419 0.0405
Loa Loa (eye worm) MBOAT family protein 0.057 0.7036 1
Echinococcus multilocularis tumor protein p63 0.0356 0.4326 0.4317
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.002 0.0029
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.029 0.1681
Schistosoma mansoni zinc finger protein 0.057 0.7036 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0056 0.0506 0.0719
Mycobacterium tuberculosis Probable amidase AmiD (acylamidase) (acylase) 0.0026 0.0123 0.0659
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.029 0.1681
Brugia malayi Amidase family protein 0.0026 0.0123 0.0175
Brugia malayi amidase 0.0214 0.2511 0.3569
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0049 0.0419 0.0405
Trypanosoma brucei glycerol uptake protein, putative 0.0049 0.0419 0.2467
Echinococcus granulosus GPCR family 2 0.0018 0.002 0.0007
Loa Loa (eye worm) hypothetical protein 0.0049 0.0419 0.0569
Echinococcus granulosus tumor protein p63 0.0356 0.4326 0.614
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.002 0.0007
Brugia malayi T-complex protein 1, beta subunit 0.0027 0.0139 0.0197
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0056 0.0506 0.0693
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0049 0.0419 0.0569
Echinococcus granulosus fatty acid amide hydrolase 1 0.0026 0.0123 0.0154
Plasmodium vivax PST-A protein 0.0146 0.1654 1
Mycobacterium tuberculosis Possible lysophospholipase 0.0146 0.1654 1
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.057 0.7036 1
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0049 0.0419 0.0576
Plasmodium falciparum lysophospholipase, putative 0.0146 0.1654 1
Mycobacterium ulcerans lysophospholipase 0.0146 0.1654 1
Treponema pallidum alginate O-acetylation protein (algI) 0.0049 0.0419 1
Brugia malayi MBOAT family protein 0.057 0.7036 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.002 0.0005
Trichomonas vaginalis valacyclovir hydrolase, putative 0.0146 0.1654 1
Trypanosoma cruzi glycerol uptake protein, putative 0.0049 0.0419 0.2467
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0114 0.1241 0.7483
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0049 0.0419 0.0576
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.029 0.0276
Trypanosoma cruzi monoglyceride lipase, putative 0.0146 0.1654 1
Brugia malayi diacylglycerol acyltransferase 0.0049 0.0419 0.0596
Loa Loa (eye worm) MH2 domain-containing protein 0.0129 0.1432 0.2012
Brugia malayi Thioredoxin reductase 0.005 0.0429 0.061
Echinococcus multilocularis muscleblind protein 0.0148 0.1675 0.1663
Echinococcus granulosus o acyltransferase membrane bound domain 0.0049 0.0419 0.0576
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0049 0.0419 0.0576
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.029 0.1681
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0112 0.0595
Loa Loa (eye worm) hypothetical protein 0.0148 0.1675 0.2359
Mycobacterium tuberculosis Probable amidase AmiB2 (aminohydrolase) 0.0026 0.0123 0.0659
Brugia malayi MBOAT family protein 0.0049 0.0419 0.0596
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0146 0.1654 1
Schistosoma mansoni fatty-acid amide hydrolase 0.0214 0.2511 0.3556
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0112 0.0595
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0049 0.0419 0.0576
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.002 0.0007
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0112 0.0595
Giardia lamblia TCP-1 chaperonin subunit beta 0.0027 0.0139 1
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0027 0.0139 0.0176
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.029 0.1681
Schistosoma mansoni sterol O-acyltransferase 1 0.0049 0.0419 0.0576
Mycobacterium tuberculosis Probable oxidoreductase 0.0126 0.1403 0.8468
Mycobacterium ulcerans amidase 0.0026 0.0123 0.0659
Toxoplasma gondii t-complex protein beta subunit 0.0027 0.0139 0.2988
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0146 0.1654 1
Loa Loa (eye worm) MBOAT family protein 0.0049 0.0419 0.0569
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.029 0.1681
Trichomonas vaginalis transmembrane protein nessy, putative 0.0049 0.0419 0.2467
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0239 0.0756
Chlamydia trachomatis glutamyl-tRNA(Gln) amidotransferase subunit A 0.0026 0.0123 1
Trypanosoma brucei fatty-acid amide hydrolase, putative 0.0026 0.0123 0.0659
Trichomonas vaginalis chaperonin, putative 0.0027 0.0139 0.0755
Schistosoma mansoni hypothetical protein 0.0018 0.002 0.0007
Trypanosoma cruzi glycerol uptake protein, putative 0.0049 0.0419 0.2467
Schistosoma mansoni hypothetical protein 0.0038 0.0281 0.0379
Brugia malayi Hhat protein 0.0049 0.0419 0.0596
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0049 0.0419 0.9758
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0049 0.0419 0.0576
Echinococcus multilocularis zinc finger protein 0.0521 0.6412 0.6407
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0112 0.0595
Mycobacterium tuberculosis Probable amidase AmiA2 (aminohydrolase) 0.0026 0.0123 0.0659
Loa Loa (eye worm) hypothetical protein 0.0056 0.0506 0.0693
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0056 0.0506 0.0719
Mycobacterium tuberculosis Probable reductase 0.0114 0.1241 0.7483
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0422 0.0408
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0458 0.0632
Loa Loa (eye worm) hypothetical protein 0.0148 0.1675 0.2359
Loa Loa (eye worm) transcription factor SMAD2 0.0129 0.1432 0.2012
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.005 0.0429 0.2528
Echinococcus multilocularis muscleblind protein 1 0.0148 0.1675 0.1663
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0049 0.0419 0.0576
Schistosoma mansoni glutamyl-tRNA(Gln) amidotransferase subunit A 0.0026 0.0123 0.0154
Plasmodium falciparum esterase, putative 0.0146 0.1654 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.029 0.1681
Trypanosoma cruzi amidase, putative 0.0026 0.0123 0.0659
Onchocerca volvulus 0.0052 0.0458 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0458 0.0625
Plasmodium vivax glutamyl-tRNA(Gln) amidotransferase subunit A, putative 0.0026 0.0123 0.0659
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0146 0.1654 1
Brugia malayi Muscleblind-like protein 0.0148 0.1675 0.2381
Trichomonas vaginalis conserved hypothetical protein 0.0146 0.1654 1
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0049 0.0419 0.2467
Echinococcus granulosus muscleblind protein 0.0148 0.1675 0.2365
Loa Loa (eye worm) amidase 0.0026 0.0123 0.0146
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0015 0.0021
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0114 0.1241 0.7483
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.057 0.7036 0.7032
Leishmania major glycerol uptake protein, putative 0.0049 0.0419 0.2467
Mycobacterium ulcerans hypothetical protein 0.0146 0.1654 1
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0049 0.0419 0.0405
Schistosoma mansoni inositol monophosphatase 0.0039 0.029 0.0392
Echinococcus granulosus o acyltransferase membrane bound domain 0.0049 0.0419 0.0576
Wolbachia endosymbiont of Brugia malayi aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0026 0.0123 0.3917
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0419 0.2467
Mycobacterium ulcerans amidase 0.0026 0.0123 0.0659
Echinococcus granulosus sterol O acyltransferase 1 0.0049 0.0419 0.0576
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0027 0.0139 0.0755
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0027 0.0139 0.0124
Trypanosoma brucei trypanothione reductase 0.005 0.0429 0.2528
Trypanosoma brucei monoglyceride lipase, putative 0.0146 0.1654 1
Schistosoma mansoni hypothetical protein 0.0018 0.002 0.0007
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0049 0.0419 0.0576
Mycobacterium ulcerans aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0026 0.0123 0.0659
Leishmania major T-complex protein 1, beta subunit, putative 0.0027 0.0139 0.0755
Leishmania major hypothetical protein, conserved 0.0025 0.0112 0.0595
Treponema pallidum aspartyl/glutamyl-tRNA amidotransferase subunit A 0.0026 0.0123 0.267
Loa Loa (eye worm) thioredoxin reductase 0.005 0.0429 0.0583
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0112 0.0595
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.0429 0.0415
Brugia malayi MBOAT family protein 0.0049 0.0419 0.0596
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0049 0.0419 0.0405
Plasmodium falciparum lysophospholipase, putative 0.0146 0.1654 1
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0419 0.2467
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0049 0.0419 0.0405
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.029 0.1001
Schistosoma mansoni hypothetical protein 0.0018 0.002 0.0007
Toxoplasma gondii thioredoxin reductase 0.005 0.0429 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0422 0.058
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0114 0.1241 0.7306
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.0422 0.0573
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.0139 0.0176
Mycobacterium ulcerans amidase 0.0026 0.0123 0.0659
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.029 0.1681
Trichomonas vaginalis conserved hypothetical protein 0.0146 0.1654 1
Leishmania major glycerol uptake protein, putative 0.0049 0.0419 0.2467
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0214 0.2511 0.25
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0126 0.1403 0.836
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0422 0.0408
Schistosoma mansoni inositol monophosphatase 0.0039 0.029 0.0392
Trypanosoma cruzi GUP1, putative 0.0049 0.0419 0.2467
Plasmodium falciparum lysophospholipase, putative 0.0146 0.1654 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0422 0.058
Brugia malayi putative amidase 0.0026 0.0123 0.0175
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.002 0.0005
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.0139 0.0176
Loa Loa (eye worm) hypothetical protein 0.0049 0.0419 0.0569
Brugia malayi MBOAT family protein 0.0049 0.0419 0.0596
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.0429 0.059
Brugia malayi Latrophilin receptor protein 2 0.0018 0.002 0.0029
Leishmania major trypanothione reductase 0.005 0.0429 0.2528
Brugia malayi MBOAT family protein 0.0049 0.0419 0.0596
Leishmania major glycerol uptake protein, putative 0.0049 0.0419 0.2467
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.0422 0.06
Plasmodium falciparum T-complex protein 1 subunit beta 0.0027 0.0139 0.0755
Plasmodium vivax glutathione reductase, putative 0.005 0.0429 0.2528
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0146 0.1654 1
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0429 0.2528
Trypanosoma brucei glycerol uptake protein, putative 0.0049 0.0419 0.2467
Schistosoma mansoni hypothetical protein 0.0049 0.0419 0.0576
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0049 0.0419 0.0576
Loa Loa (eye worm) inositol-1 0.0039 0.029 0.0385
Echinococcus granulosus glutamyl tRNAGln amidotransferase subunit A 0.0026 0.0123 0.0154
Brugia malayi Amidase family protein 0.0026 0.0123 0.0175
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0049 0.0419 0.2467
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0281 0.04
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0126 0.1403 0.8468
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0049 0.0419 0.1851
Mycobacterium ulcerans peptide amidase, GatA 0.0026 0.0123 0.0659
Loa Loa (eye worm) amidase 0.0026 0.0123 0.0146
Echinococcus granulosus fatty acid amide hydrolase 1 0.0214 0.2511 0.3556
Echinococcus granulosus zinc finger protein 0.0521 0.6412 0.9111
Mycobacterium tuberculosis Possible amidase (aminohydrolase) 0.0026 0.0123 0.0659
Entamoeba histolytica hypothetical protein, conserved 0.0049 0.0419 0.1851
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0027 0.0139 0.0755
Brugia malayi MH2 domain containing protein 0.0129 0.1432 0.2035
Plasmodium falciparum glutathione reductase 0.005 0.0429 0.2528
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0114 0.1241 0.7483
Brugia malayi hypothetical protein 0.0025 0.0112 0.016
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0026 0.0123 0.0108
Brugia malayi glutathione reductase 0.005 0.0429 0.061
Mycobacterium ulcerans amidase 0.0026 0.0123 0.0659
Schistosoma mansoni fatty-acid amide hydrolase 0.0026 0.0123 0.0154
Mycobacterium leprae POSSIBLE LYSOPHOSPHOLIPASE 0.0146 0.1654 1
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0049 0.0419 0.0576
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0112 0.2353
Loa Loa (eye worm) hhat protein 0.0049 0.0419 0.0569
Entamoeba histolytica hypothetical protein 0.0049 0.0419 0.1851
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0049 0.0419 0.0405
Entamoeba histolytica vacuolar protein sorting 26 0.0049 0.0419 0.1851
Brugia malayi Inositol-1 0.0039 0.029 0.0413
Trypanosoma brucei monoglyceride lipase, putative 0.0146 0.1654 1
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0049 0.0419 0.0405
Trypanosoma cruzi amidase, putative 0.0026 0.0123 0.0659
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0027 0.0139 0.0176
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.029 0.6651
Leishmania major glycerol uptake protein, putative 0.0049 0.0419 0.2467
Echinococcus multilocularis fatty acid amide hydrolase 1 0.0214 0.2511 0.25
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0049 0.0419 0.0569
Echinococcus granulosus fatty acid amide hydrolase 1 0.0214 0.2511 0.3556
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0422 0.058
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0049 0.0419 0.0405
Leishmania major glycerol uptake protein, putative 0.0049 0.0419 0.2467
Loa Loa (eye worm) hypothetical protein 0.0025 0.0112 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0419 0.2467
Brugia malayi T-complex protein 1, beta subunit 0.0027 0.0139 0.0197
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0027 0.0139 0.0755
Echinococcus multilocularis glutamyl tRNA(Gln) amidotransferase subunit A 0.0026 0.0123 0.0108
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0126 0.1403 0.8468
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0049 0.0419 0.1851
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.029 1
Leishmania major monoglyceride lipase, putative 0.0146 0.1654 1
Leishmania major hypothetical protein, conserved 0.0049 0.0419 0.2467
Plasmodium falciparum thioredoxin reductase 0.005 0.0429 0.2528
Trypanosoma cruzi GUP1, putative 0.0049 0.0419 0.2467
Toxoplasma gondii hypothetical protein 0.0049 0.0419 0.9758
Loa Loa (eye worm) MBOAT family protein 0.0049 0.0419 0.0569
Entamoeba histolytica hydrolase, alpha/beta fold family domain containing protein 0.0146 0.1654 1
Trichomonas vaginalis porcupine, putative 0.0049 0.0419 0.2467
Loa Loa (eye worm) hypothetical protein 0.0038 0.0281 0.0372
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0112 0.0595
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0049 0.0419 0.9758
Loa Loa (eye worm) hypothetical protein 0.0049 0.0419 0.0569
Leishmania major hypothetical protein, conserved 0.0026 0.0123 0.0659
Loa Loa (eye worm) T-complex protein 1 0.0027 0.0139 0.0169
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0422 0.058
Mycobacterium ulcerans amidase 0.0026 0.0123 0.0659
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.029 0.1681
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0239 0.1364
Mycobacterium tuberculosis Probable dehydrogenase 0.0114 0.1241 0.7483
Echinococcus multilocularis GPCR, family 2 0.0018 0.002 0.0005
Plasmodium vivax thioredoxin reductase, putative 0.005 0.0429 0.2528
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0146 0.1654 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0422 0.058
Loa Loa (eye worm) hypothetical protein 0.0214 0.2511 0.3551
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0049 0.0419 0.0576
Echinococcus granulosus o acyltransferase membrane bound domain 0.0049 0.0419 0.0576
Loa Loa (eye worm) hypothetical protein 0.0049 0.0419 0.0569
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0146 0.1654 1
Mycobacterium tuberculosis Probable amidase AmiC (aminohydrolase) 0.0026 0.0123 0.0659
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0114 0.1241 0.7483
Loa Loa (eye worm) glutathione reductase 0.005 0.0429 0.0583
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0027 0.0139 0.0755
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.029 0.0392
Schistosoma mansoni amidase 0.0214 0.2511 0.3556
Loa Loa (eye worm) hhat protein 0.0049 0.0419 0.0569
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0049 0.0419 0.1851
Schistosoma mansoni hypothetical protein 0.0018 0.002 0.0007

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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