Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0023 | 0.0192 | 0.0913 |
Onchocerca volvulus | 0.0181 | 0.2969 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0015 | 0.0056 | 0.0056 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0023 | 0.0192 | 0.0646 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0023 | 0.0192 | 0.0646 |
Schistosoma mansoni | pcd6 interacting protein-related | 0.0023 | 0.0192 | 0.0913 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type | 0.0023 | 0.0192 | 0.0913 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0026 | 0.024 | 0.0249 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0057 | 0.0789 | 0.2657 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0026 | 0.024 | 0.3123 |
Brugia malayi | Cell death protein 3 precursor | 0.0026 | 0.024 | 0.0809 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Leishmania major | metacaspase, putative | 0.0026 | 0.024 | 0.3123 |
Echinococcus granulosus | caspase 3 apoptosis cysteine peptidase | 0.0026 | 0.024 | 0.024 |
Trypanosoma brucei | low molecular weight protein tyrosine phosphatase, putative | 0.0056 | 0.0769 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0015 | 0.0056 | 0.0724 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0023 | 0.0192 | 0.0192 |
Trypanosoma cruzi | small ubiquitin protein, putative | 0.003 | 0.0311 | 0.4037 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0026 | 0.024 | 0.0249 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0023 | 0.0192 | 0.0646 |
Schistosoma mansoni | protein phosphatase 2C | 0.0015 | 0.0056 | 0.0265 |
Trypanosoma brucei | metacaspase | 0.0026 | 0.024 | 0.3123 |
Trichomonas vaginalis | pten, drome, putative | 0.0023 | 0.0192 | 0.0199 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0057 | 0.0789 | 0.0789 |
Trypanosoma cruzi | small ubiquitin protein, putative | 0.003 | 0.0311 | 0.4037 |
Brugia malayi | protein-tyrosine phosphatase Lar-like precursor, putative | 0.0023 | 0.0192 | 0.0646 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0023 | 0.0192 | 0.0192 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0023 | 0.0192 | 0.0192 |
Brugia malayi | Protein-tyrosine phosphatase 1 | 0.0023 | 0.0192 | 0.0646 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0181 | 0.2969 | 0.3079 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0131 | 0.2101 | 0.2101 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Echinococcus multilocularis | caspase | 0.0026 | 0.024 | 0.1144 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0023 | 0.0192 | 0.0192 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0026 | 0.024 | 0.0249 |
Schistosoma mansoni | eyes absent homolog | 0.0085 | 0.1287 | 0.6126 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0026 | 0.024 | 0.0249 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Echinococcus multilocularis | caspase 8 | 0.0026 | 0.024 | 0.1144 |
Entamoeba histolytica | ubiquitin like protein | 0.003 | 0.0311 | 0.0322 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0023 | 0.0192 | 0.0646 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0023 | 0.0192 | 0.0646 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase F | 0.0023 | 0.0192 | 0.0913 |
Plasmodium falciparum | metacaspase 1 | 0.0026 | 0.024 | 0.7736 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0023 | 0.0192 | 0.0646 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.024 | 0.0249 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0015 | 0.0056 | 0.0724 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0023 | 0.0192 | 0.0192 |
Brugia malayi | Protein-tyrosine phosphatase | 0.0023 | 0.0192 | 0.0646 |
Trypanosoma cruzi | tyrosine specific protein phosphatase, putative | 0.0023 | 0.0192 | 0.2494 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Trypanosoma cruzi | metacaspase, putative | 0.0026 | 0.024 | 0.3123 |
Schistosoma mansoni | protein tyrosine phosphatase | 0.0023 | 0.0192 | 0.0913 |
Echinococcus multilocularis | caspase 2 | 0.0026 | 0.024 | 0.1144 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.024 | 0.0809 |
Echinococcus multilocularis | 0.0023 | 0.0192 | 0.0913 | |
Leishmania major | protein-tyrosine phosphatase 1-like protein | 0.0023 | 0.0192 | 0.2494 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Schistosoma mansoni | protein tyrosine phosphatase n11 (shp2) | 0.0131 | 0.2101 | 1 |
Schistosoma mansoni | rgs-gaip interacting protein gipc | 0.0023 | 0.0192 | 0.0913 |
Brugia malayi | Low molecular weight phosphotyrosine protein phosphatase containing protein | 0.0181 | 0.2969 | 1 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0026 | 0.024 | 0.7736 |
Schistosoma mansoni | protein tyrosine phosphatase | 0.0023 | 0.0192 | 0.0913 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Schistosoma mansoni | jumonji domain containing protein | 0.0015 | 0.0056 | 0.0265 |
Leishmania major | tyrosine specific protein phosphatase, putative | 0.0023 | 0.0192 | 0.2494 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0181 | 0.2969 | 0.3079 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0015 | 0.0056 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.024 | 0.0809 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0181 | 0.2969 | 0.3079 |
Schistosoma mansoni | receptor protein tyrosine phosphatase | 0.0023 | 0.0192 | 0.0913 |
Entamoeba histolytica | dual specificity protein phosphatase, putative | 0.056 | 0.9645 | 1 |
Plasmodium falciparum | small ubiquitin-related modifier | 0.003 | 0.0311 | 1 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0181 | 0.2969 | 0.3079 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.1287 | 0.4335 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0057 | 0.0789 | 0.3755 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0057 | 0.0789 | 0.3755 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase zeta | 0.0023 | 0.0192 | 0.0913 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0023 | 0.0192 | 0.0192 |
Trypanosoma cruzi | metacaspase, putative | 0.0026 | 0.024 | 0.3123 |
Brugia malayi | jmjC domain containing protein | 0.0057 | 0.0789 | 0.2657 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0181 | 0.2969 | 0.3079 |
Schistosoma mansoni | ubiquitin-like protein sumo/smt3-related | 0.003 | 0.0311 | 0.1478 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0023 | 0.0192 | 0.0192 |
Brugia malayi | jmjC domain containing protein | 0.0057 | 0.0789 | 0.2657 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0015 | 0.0056 | 0.0724 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0026 | 0.024 | 0.0249 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0056 | 0.0188 |
Trypanosoma cruzi | metacaspase, putative | 0.0026 | 0.024 | 0.3123 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0023 | 0.0192 | 0.0646 |
Loa Loa (eye worm) | protein-tyrosine-phosphatase | 0.0023 | 0.0192 | 0.0646 |
Echinococcus granulosus | phd:f box containing protein | 0.0015 | 0.0056 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0056 | 0.0188 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0015 | 0.0056 | 0.0724 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0015 | 0.0056 | 0.0265 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Schistosoma mansoni | protein-tyrosine phosphatase n9 | 0.0023 | 0.0192 | 0.0913 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0023 | 0.0192 | 0.0192 |
Schistosoma mansoni | receptor protein tyrosine phosphatase r (pcptp1) | 0.0023 | 0.0192 | 0.0913 |
Echinococcus granulosus | Small ubiquitin modifier 2 | 0.003 | 0.0311 | 0.0311 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0026 | 0.024 | 0.1144 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0026 | 0.024 | 0.0249 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0023 | 0.0192 | 0.0913 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0023 | 0.0192 | 0.0646 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase zeta | 0.0023 | 0.0192 | 0.0192 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0023 | 0.0192 | 0.0199 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0181 | 0.2969 | 0.3079 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0056 | 0.0188 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0056 | 0.0769 | 0.0798 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0131 | 0.2101 | 0.7076 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0023 | 0.0192 | 0.0646 |
Trichomonas vaginalis | low molecular weight protein tyrosine phosphatase, putative | 0.0056 | 0.0769 | 0.0798 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.024 | 0.0249 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0015 | 0.0056 | 0.0188 |
Leishmania major | small ubiquitin protein, putative | 0.003 | 0.0311 | 0.4037 |
Echinococcus multilocularis | hypothetical protein | 0.0023 | 0.0192 | 0.0913 |
Trichomonas vaginalis | conserved hypothetical protein | 0.003 | 0.0311 | 0.0322 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0015 | 0.0056 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0131 | 0.2101 | 1 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Plasmodium vivax | hypothetical protein, conserved | 0.0026 | 0.024 | 0.7736 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Brugia malayi | mucosa associated lymphoid tissue lymphoma translocation protein 1 | 0.0026 | 0.024 | 0.0809 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0057 | 0.0789 | 0.3755 |
Loa Loa (eye worm) | protein tyrosine phosphatase | 0.0023 | 0.0192 | 0.0646 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0023 | 0.0192 | 0.0192 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0015 | 0.0056 | 0.0265 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0057 | 0.0789 | 0.3755 |
Echinococcus multilocularis | phd:f box containing protein | 0.0015 | 0.0056 | 0.0265 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0026 | 0.024 | 0.7736 |
Schistosoma mansoni | protein-tyrosine phosphatase non-receptor type nt5 | 0.0023 | 0.0192 | 0.0913 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0023 | 0.0192 | 0.0192 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0057 | 0.0789 | 0.0789 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0023 | 0.0192 | 0.0646 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Trypanosoma brucei | metacaspase MCA3 | 0.0026 | 0.024 | 0.3123 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Echinococcus multilocularis | Small ubiquitin modifier 2 | 0.003 | 0.0311 | 0.1478 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0026 | 0.024 | 0.0249 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.0023 | 0.0192 | 0.0913 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0023 | 0.0192 | 0.0646 |
Brugia malayi | Ubiquitin-like protein SMT3 | 0.003 | 0.0311 | 0.1046 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0026 | 0.024 | 0.0249 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0023 | 0.0192 | 0.0913 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0026 | 0.024 | 0.7736 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0023 | 0.0192 | 0.0646 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0023 | 0.0192 | 0.0913 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0056 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0026 | 0.024 | 0.0249 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0023 | 0.0192 | 0.0913 |
Trypanosoma cruzi | tyrosine specific protein phosphatase, putative | 0.0023 | 0.0192 | 0.2494 |
Plasmodium vivax | small ubiquitin-related modifier, putative | 0.003 | 0.0311 | 1 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.024 | 0.0249 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Brugia malayi | Dual specificity protein phosphatase CDC14B | 0.0023 | 0.0192 | 0.0646 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Trypanosoma brucei | metacaspase 5, putative | 0.0026 | 0.024 | 0.3123 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0015 | 0.0056 | 0.0265 |
Trypanosoma brucei | Metacaspase-4 | 0.0026 | 0.024 | 0.3123 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0023 | 0.0192 | 0.0192 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0056 | 0.0769 | 1 |
Loa Loa (eye worm) | protein-tyrosine phosphatase 1 | 0.0023 | 0.0192 | 0.0646 |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0023 | 0.0192 | 0.0913 |
Mycobacterium ulcerans | phosphotyrosine protein phosphatase PtpA | 0.0181 | 0.2969 | 0.5 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase zeta | 0.0023 | 0.0192 | 0.0913 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0015 | 0.0056 | 0.0056 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0023 | 0.0192 | 0.0646 |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0023 | 0.0192 | 0.0913 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0023 | 0.0192 | 0.0913 |
Leishmania major | hypothetical protein, conserved | 0.0056 | 0.0769 | 1 |
Trypanosoma brucei | metacaspase MCA2 | 0.0026 | 0.024 | 0.3123 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Loa Loa (eye worm) | fibronectin type III domain-containing protein | 0.0023 | 0.0192 | 0.0646 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0023 | 0.0192 | 0.0913 |
Giardia lamblia | Low molecular weight protein-tyrosine-phosphatase | 0.0181 | 0.2969 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0015 | 0.0056 | 0.0188 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0023 | 0.0192 | 0.0913 |
Giardia lamblia | Sentrin | 0.003 | 0.0311 | 0.1046 |
Schistosoma mansoni | receptor protein tyrosine phosphatase n (ia2) | 0.0023 | 0.0192 | 0.0913 |
Trypanosoma cruzi | tyrosine specific protein phosphatase, putative | 0.0023 | 0.0192 | 0.2494 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Schistosoma mansoni | receptor protein tyrosine phosphatase n (ia2) | 0.0023 | 0.0192 | 0.0913 |
Brugia malayi | Protein-tyrosine phosphatase | 0.0023 | 0.0192 | 0.0646 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type | 0.0023 | 0.0192 | 0.0913 |
Brugia malayi | jmjC domain containing protein | 0.0015 | 0.0056 | 0.0188 |
Schistosoma mansoni | caspase-3 (C14 family) | 0.0026 | 0.024 | 0.1144 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0181 | 0.2969 | 0.3079 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Schistosoma mansoni | protein tyrosine phosphatase | 0.0023 | 0.0192 | 0.0913 |
Plasmodium falciparum | metacaspase-like protein | 0.0026 | 0.024 | 0.7736 |
Echinococcus multilocularis | caspase 3, apoptosis cysteine peptidase | 0.0026 | 0.024 | 0.1144 |
Trichomonas vaginalis | low molecular weight protein-tyrosine-phosphatase, putative | 0.0181 | 0.2969 | 0.3079 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.1287 | 0.4335 |
Schistosoma mansoni | jumonji domain containing protein | 0.0057 | 0.0789 | 0.3755 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0023 | 0.0192 | 0.0913 |
Plasmodium vivax | JmjC domain containing protein | 0.0015 | 0.0056 | 0.1793 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0015 | 0.0056 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Echinococcus multilocularis | Receptor type tyrosine protein phosphatase O | 0.0023 | 0.0192 | 0.0913 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Trypanosoma brucei | protein tyrosine phosphatase 1 | 0.0023 | 0.0192 | 0.2494 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0015 | 0.0056 | 0.0265 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0026 | 0.024 | 0.3123 |
Loa Loa (eye worm) | dual specificity protein phosphatase CDC14B | 0.0023 | 0.0192 | 0.0646 |
Trypanosoma cruzi | metacaspase, putative | 0.0026 | 0.024 | 0.3123 |
Schistosoma mansoni | subfamily C14A unassigned peptidase (C14 family) | 0.0026 | 0.024 | 0.1144 |
Onchocerca volvulus | Cell death protein 3 homolog | 0.0026 | 0.024 | 0.0174 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0026 | 0.024 | 0.1144 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0131 | 0.2101 | 1 |
Loa Loa (eye worm) | phosphotyrosine protein phosphatase | 0.0181 | 0.2969 | 1 |
Entamoeba histolytica | Pten 3-phosphoinositide phosphatase, putative | 0.0023 | 0.0192 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Toxoplasma gondii | small ubiquitin family modifier, putative | 0.003 | 0.0311 | 1 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0023 | 0.0192 | 0.0913 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0015 | 0.0056 | 0.1793 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0131 | 0.2101 | 0.7076 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Echinococcus granulosus | caspase | 0.0026 | 0.024 | 0.024 |
Schistosoma mansoni | phd/f-box containing protein | 0.0015 | 0.0056 | 0.0265 |
Brugia malayi | hypothetical protein | 0.0085 | 0.1287 | 0.4335 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0023 | 0.0192 | 0.0913 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Trypanosoma brucei | small ubiquitin-related modifier | 0.003 | 0.0311 | 0.4037 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0023 | 0.0192 | 0.0913 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Plasmodium vivax | metacaspase 1, putative | 0.0026 | 0.024 | 0.7736 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0023 | 0.0192 | 0.0646 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0015 | 0.0056 | 0.1793 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0015 | 0.0056 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0023 | 0.0192 | 0.0913 |
Schistosoma mansoni | non-receptor protein-tyrosine phosphatase | 0.0023 | 0.0192 | 0.0913 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0131 | 0.2101 | 0.2101 |
Giardia lamblia | Protein tyrosine phosphatase | 0.0023 | 0.0192 | 0.0646 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0015 | 0.0056 | 0.0056 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Trichomonas vaginalis | pps1 dual specificty phosphatase, putative | 0.056 | 0.9645 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0056 | 0.0188 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.024 | 0.0249 |
Loa Loa (eye worm) | SMO-1 protein | 0.003 | 0.0311 | 0.1046 |
Mycobacterium tuberculosis | Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) | 0.0125 | 0.1989 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0056 | 0.0188 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase zeta | 0.0023 | 0.0192 | 0.0192 |
Echinococcus granulosus | caspase 8 | 0.0026 | 0.024 | 0.024 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0023 | 0.0192 | 0.0913 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0056 | 0.0769 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.024 | 0.0249 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Echinococcus granulosus | protein tyrosine phosphatase n9 | 0.0023 | 0.0192 | 0.0192 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Echinococcus multilocularis | protein tyrosine phosphatase n9 | 0.0023 | 0.0192 | 0.0913 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0015 | 0.0056 | 0.1793 |
Brugia malayi | hypothetical protein | 0.0023 | 0.0192 | 0.0646 |
Echinococcus granulosus | Receptor type tyrosine protein phosphatase O | 0.0023 | 0.0192 | 0.0192 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0023 | 0.0192 | 0.0646 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0023 | 0.0192 | 0.0913 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase H | 0.0023 | 0.0192 | 0.0913 |
Echinococcus granulosus | caspase 2 | 0.0026 | 0.024 | 0.024 |
Entamoeba histolytica | protein tyrosine phosphatase, putative | 0.0023 | 0.0192 | 0.0199 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0026 | 0.024 | 0.0249 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0023 | 0.0192 | 0.0192 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 35.5 % | Antitumor activity against mouse L1210 cells allografted in BDF1 mouse assessed as increase of host life span at 25 mg/kg, ip qd for 5 days | ChEMBL. | 458820 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.