TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 327.378 | Formula: C18H21N3O3
H donors: 2 H acceptors: 2 LogP: 2.1 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: CCOc1ncccc1CNC(=O)NC1CCOc2c1cccc2
InChi: 1S/C18H21N3O3/c1-2-23-17-13(6-5-10-19-17)12-20-18(22)21-15-9-11-24-16-8-4-3-7-14(15)16/h3-8,10,15H,2,9,11-12H2,1H3,(H2,20,21,22)
InChiKey: BYSUFEWDBVGEGC-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Plasmodium vivax	thioredoxin reductase, putative	0.003	0.0843	1
Toxoplasma gondii	N-acetylgalactosaminyl transferase	0.0016	0.0302	0.1596
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Echinococcus granulosus	neuropeptide Y receptor	0.0029	0.0802	0.0799
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0029	0.0802	0.0857
Schistosoma mansoni	growth hormone secretagogue receptor	0.0029	0.0802	0.0857
Mycobacterium tuberculosis	Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed))	0.0022	0.0543	0.14
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0029	0.0802	0.0802
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Echinococcus multilocularis	neuropeptides capa receptor	0.0029	0.0802	0.0799
Trypanosoma brucei	unspecified product	0.0015	0.0282	0.2473
Echinococcus granulosus	survival motor neuron protein 1	0.027	1	1
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0029	0.0802	0.0799
Echinococcus granulosus	thioredoxin glutathione reductase	0.003	0.0858	0.0855
Echinococcus multilocularis	neuropeptide s receptor	0.0029	0.0802	0.0799
Echinococcus multilocularis	ETS transcription factor Elf 5	0.0012	0.016	0.0156
Leishmania major	trypanothione reductase	0.003	0.0843	1
Mycobacterium tuberculosis	NAD(P)H quinone reductase LpdA	0.0076	0.2595	0.7854
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0029	0.0802	0.0857
Loa Loa (eye worm)	beta-1,4-galactosyltransferase VII	0.0038	0.1165	0.1162
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0029	0.0802	0.0799
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0008	0.0007	0.0004
Schistosoma mansoni	neuropeptide F-like receptor	0.0029	0.0802	0.0857
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0029	0.0802	0.0799
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0543	0.5972
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Brugia malayi	larval opioid receptor	0.0029	0.0802	0.0802
Echinococcus granulosus	neuropeptides capa receptor	0.0029	0.0802	0.0799
Schistosoma mansoni	elf1	0.0012	0.016	0.0165
Brugia malayi	GnHR receptor homolog	0.0029	0.0802	0.0802
Onchocerca volvulus		0.0024	0.0621	0.0896
Trypanosoma cruzi	PAB1-binding protein , putative	0.002	0.0462	0.4894
Loa Loa (eye worm)	hypothetical protein	0.0008	0.0007	0.0004
Brugia malayi	RE15519p	0.0029	0.0802	0.0802
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Echinococcus granulosus	ETS domain containing protein Elk 1	0.0012	0.016	0.0156
Brugia malayi	Dopamine receptor protein 1	0.0029	0.0802	0.0802
Echinococcus multilocularis	serotonin receptor	0.0029	0.0802	0.0799
Echinococcus granulosus	ewsr:fli fusion protein type	0.0012	0.016	0.0156
Brugia malayi	Ets-domain containing protein	0.0083	0.2856	0.2856
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Echinococcus multilocularis	neuropeptide receptor A26	0.0029	0.0802	0.0799
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0029	0.0802	0.0857
Echinococcus granulosus	rhodopsin orphan GPCR	0.0029	0.0802	0.0799
Loa Loa (eye worm)	hypothetical protein	0.0008	0.0007	0.0004
Trypanosoma brucei	DNA polymerase eta, putative	0.0022	0.0543	0.5972
Brugia malayi	Dopamine receptor protein 2	0.0029	0.0802	0.0802
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0029	0.0802	0.0857
Brugia malayi	hypothetical protein	0.0029	0.0802	0.0802
Brugia malayi	transcription factor E74 isoform	0.0012	0.016	0.016
Echinococcus granulosus	GA binding protein alpha chain	0.0083	0.2856	0.2853
Trypanosoma brucei	DNA polymerase kappa, putative	0.0015	0.0282	0.2473
Echinococcus multilocularis	dihydrolipoamide dehydrogenase	0.001	0.0098	0.0094
Echinococcus granulosus	allatostatin A receptor	0.0029	0.0802	0.0799
Onchocerca volvulus		0.0029	0.0802	0.1159
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0008	0.0007	0.0004
Echinococcus granulosus	7TM GPCR rhodopsin	0.0029	0.0802	0.0799
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0008	0.0007	0.0004
Echinococcus multilocularis	allatostatin A receptor	0.0029	0.0802	0.0799
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0008	0.0007	0.0007
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Schistosoma mansoni	beta-14-galactosyltransferase	0.0038	0.1165	0.1249
Plasmodium falciparum	glutathione reductase	0.003	0.0843	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0543	0.5972
Schistosoma mansoni	beta-14-galactosyltransferase	0.0038	0.1165	0.1249
Schistosoma mansoni	amine GPCR	0.0029	0.0802	0.0857
Loa Loa (eye worm)	galactosyltransferase	0.0038	0.1165	0.1162
Schistosoma mansoni	beta-14-galactosyltransferase	0.0023	0.0565	0.0602
Brugia malayi	Ets-domain containing protein	0.0083	0.2856	0.2856
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0024	0.0621	0.0663
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0029	0.0802	0.0799
Leishmania major	hypothetical protein, conserved	0.002	0.0462	0.4894
Echinococcus multilocularis	G protein coupled receptor 139	0.0029	0.0802	0.0799
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Mycobacterium tuberculosis	Putative ferredoxin reductase	0.0068	0.2304	0.6941
Trypanosoma brucei	trypanothione reductase	0.003	0.0843	1
Onchocerca volvulus		0.0023	0.0568	0.0819
Echinococcus multilocularis	fmrfamide receptor	0.0029	0.0802	0.0799
Echinococcus multilocularis	fmrfamide receptor	0.0029	0.0802	0.0799
Onchocerca volvulus		0.0029	0.0802	0.1159
Schistosoma mansoni	cpg binding protein	0.0023	0.0568	0.0605
Echinococcus multilocularis	g protein coupled receptor	0.0029	0.0802	0.0799
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0029	0.0802	0.0857
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Echinococcus granulosus	rhodopsin orphan GPCR	0.0029	0.0802	0.0799
Brugia malayi	follicle stimulating hormone receptor	0.0029	0.0802	0.0802
Schistosoma mansoni	ets-related	0.0251	0.9277	1
Echinococcus multilocularis	somatostatin receptor	0.0029	0.0802	0.0799
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0543	0.5972
Schistosoma mansoni	neuropeptide receptor	0.0029	0.0802	0.0857
Echinococcus granulosus	Metazoa galactosyltransferase	0.0146	0.527	0.5268
Echinococcus granulosus	FTZ F1 alpha	0.0008	0.0007	0.0004
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0008	0.0007	0.0004
Echinococcus granulosus	tm gpcr rhodopsin	0.0029	0.0802	0.0799
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0024	0.0621	0.0618
Echinococcus granulosus	rhodopsin orphan GPCR	0.0029	0.0802	0.0799
Schistosoma mansoni	rab geranylgeranyl transferase alpha subunit	0.0022	0.0543	0.0578
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0022	0.0543	0.5972
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Echinococcus granulosus	sex peptide receptor	0.0029	0.0802	0.0799
Onchocerca volvulus		0.0029	0.0802	0.1159
Echinococcus multilocularis	neuropeptides capa receptor	0.0029	0.0802	0.0799
Echinococcus granulosus	dro:myosuppressin receptor	0.0029	0.0802	0.0799
Echinococcus granulosus	g protein coupled receptor	0.0029	0.0802	0.0799
Plasmodium vivax	ataxin-2 like protein, putative	0.002	0.0462	0.4894
Echinococcus granulosus	fmrfamide receptor	0.0029	0.0802	0.0799
Echinococcus granulosus	ETS transcription factor Elf 2	0.0012	0.016	0.0156
Echinococcus granulosus	hypothetical protein	0.0029	0.0802	0.0799
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0008	0.0007	0.0004
Echinococcus granulosus	neuropeptide receptor A26	0.0029	0.0802	0.0799
Entamoeba histolytica	deoxycytidyl transferase, putative	0.0022	0.0543	0.5
Onchocerca volvulus		0.0029	0.0802	0.1159
Onchocerca volvulus		0.0029	0.0802	0.1159
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0029	0.0802	0.0857
Loa Loa (eye worm)	G-protein coupled receptor	0.0029	0.0802	0.0799
Leishmania major	DNA polymerase kappa, putative,DNA polymerase IV, putative	0.0022	0.0543	0.5972
Trypanosoma cruzi	DNA polymerase eta, putative	0.0022	0.0543	0.5972
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Brugia malayi	hypothetical protein	0.0029	0.0802	0.0802
Trypanosoma brucei	DNA polymerase IV, putative	0.0022	0.0543	0.5972
Brugia malayi	Pre-SET motif family protein	0.0024	0.0621	0.0621
Trypanosoma brucei	DNA polymerase IV, putative	0.0022	0.0543	0.5972
Echinococcus multilocularis	ETS transcription factor Elf 1	0.0012	0.016	0.0156
Loa Loa (eye worm)	DNA-binding protein D-ETS-3	0.0012	0.016	0.0156
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Schistosoma mansoni	histamine h1 receptor	0.0029	0.0802	0.0857
Schistosoma mansoni	beta-14-galactosyltransferase	0.0146	0.527	0.5677
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0543	0.5972
Loa Loa (eye worm)	fli-1 protein	0.0251	0.9277	0.9276
Echinococcus multilocularis	survival motor neuron protein 1	0.027	1	1
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0029	0.0802	0.0799
Schistosoma mansoni	beta-14-galactosyltransferase	0.0038	0.1165	0.1249
Loa Loa (eye worm)	neuropeptide F receptor	0.0029	0.0802	0.0799
Echinococcus granulosus	g protein coupled receptor	0.0029	0.0802	0.0799
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0029	0.0802	0.0799
Schistosoma mansoni	hypothetical protein	0.0012	0.016	0.0165
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0029	0.0802	0.0799
Echinococcus multilocularis	g-protein coupled receptor	0.0029	0.0802	0.0799
Trichomonas vaginalis	DNA polymerase eta, putative	0.0022	0.0543	0.0658
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0543	0.054
Brugia malayi	CXXC zinc finger family protein	0.0023	0.0568	0.0568
Loa Loa (eye worm)	ImpB/MucB/SamB family protein	0.0022	0.0543	0.054
Brugia malayi	Thioredoxin reductase	0.003	0.0843	0.0843
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0008	0.0007	0.0007
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Schistosoma mansoni	hypothetical protein	0.0055	0.1803	0.1937
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0029	0.0802	0.0802
Echinococcus granulosus	orexin receptor type 2	0.0029	0.0802	0.0799
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0029	0.0802	0.0799
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0055	0.1803	0.1803
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0029	0.0802	0.0857
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0029	0.0802	0.0799
Schistosoma mansoni	hypothetical protein	0.0029	0.0802	0.0857
Schistosoma mansoni	hypothetical protein	0.0009	0.0043	0.0039
Schistosoma mansoni	neuropeptide receptor	0.0029	0.0802	0.0857
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0008	0.0007	0.0004
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0029	0.0802	0.0799
Loa Loa (eye worm)	hypothetical protein	0.0012	0.016	0.0156
Echinococcus granulosus	neuropeptide receptor	0.0029	0.0802	0.0799
Brugia malayi	hypothetical protein	0.0029	0.0802	0.0802
Echinococcus granulosus	polypeptide N acetylgalactosaminyltransferase	0.0016	0.0302	0.0298
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0022	0.0543	0.5972
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0029	0.0802	0.0799
Echinococcus multilocularis	g protein coupled receptor	0.0029	0.0802	0.0799
Echinococcus granulosus	neuropeptide FF receptor 2	0.0029	0.0802	0.0799
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0029	0.0802	0.0799
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0029	0.0802	0.0799
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0008	0.0007	0.0007
Onchocerca volvulus		0.0029	0.0802	0.1159
Onchocerca volvulus		0.0172	0.6283	0.9152
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0029	0.0802	0.0857
Brugia malayi	DNA-binding protein D-ETS-3	0.0012	0.016	0.016
Brugia malayi	Dopamine receptor	0.0029	0.0802	0.0802
Trichomonas vaginalis	DNA polymerase IV / kappa, putative	0.0022	0.0543	0.0658
Schistosoma mansoni	polyomavirus enhancer activator 3 pea3	0.0012	0.016	0.0165
Loa Loa (eye worm)	thioredoxin reductase	0.003	0.0843	0.084
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0022	0.0543	0.14
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0029	0.0802	0.0799
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0029	0.0802	0.0799
Brugia malayi	hypothetical protein	0.0029	0.0802	0.0802
Toxoplasma gondii	thioredoxin reductase	0.003	0.0843	0.583
Schistosoma mansoni	amine GPCR	0.0029	0.0802	0.0857
Mycobacterium tuberculosis	Probable dehydrogenase	0.0068	0.2304	0.6941
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0029	0.0802	0.0799
Echinococcus granulosus	protein C ets 2	0.0012	0.016	0.0156
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0543	0.5972
Loa Loa (eye worm)	glycosyl transferase	0.0016	0.0302	0.0298
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0008	0.0007	0.0007
Loa Loa (eye worm)	hypothetical protein	0.0008	0.0007	0.0004
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0049	0.1572	0.1689
Toxoplasma gondii	LsmAD domain-containing protein	0.002	0.0462	0.2853
Brugia malayi	putative neuropeptide receptor NPR1	0.0029	0.0802	0.0802
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Plasmodium falciparum	ataxin-2 like protein, putative	0.002	0.0462	0.4894
Echinococcus multilocularis	beta 1,4 galactosyltransferase 7	0.0038	0.1165	0.1162
Brugia malayi	Galactosyltransferase family protein	0.0146	0.527	0.527
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0008	0.0007	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0302	0.0298
Echinococcus multilocularis	neuropeptide Y receptor	0.0029	0.0802	0.0799
Schistosoma mansoni	phenylalanine decarboxylase	0.0038	0.1165	0.1249
Echinococcus multilocularis	ETS transcription factor Elf 2	0.0012	0.016	0.0156
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Brugia malayi	G-protein coupled receptor	0.0029	0.0802	0.0802
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0029	0.0802	0.0857
Echinococcus granulosus	tm gpcr rhodopsin	0.0029	0.0802	0.0799
Echinococcus multilocularis	sex peptide receptor	0.0029	0.0802	0.0799
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0008	0.0007	0.0004
Schistosoma mansoni	hypothetical protein	0.0029	0.0802	0.0857
Onchocerca volvulus		0.0055	0.1803	0.2619
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0029	0.0802	0.0857
Echinococcus granulosus	ETS transcription factor Elf 2	0.0012	0.016	0.0156
Schistosoma mansoni	adenoreceptor	0.0029	0.0802	0.0857
Schistosoma mansoni	amine GPCR	0.0029	0.0802	0.0857
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Echinococcus granulosus	neuropeptides capa receptor	0.0029	0.0802	0.0799
Trypanosoma cruzi	PAB1-binding protein , putative	0.002	0.0462	0.4894
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0008	0.0007	0.0007
Brugia malayi	Serotonin receptor	0.0029	0.0802	0.0802
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0029	0.0802	0.0802
Brugia malayi	hypothetical protein	0.0029	0.0802	0.0802
Brugia malayi	Melatonin receptor type 1A	0.0029	0.0802	0.0802
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0029	0.0802	0.0857
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0029	0.0802	0.0799
Giardia lamblia	DINP protein human, muc B family	0.0022	0.0543	1
Brugia malayi	dihydrolipoyl dehydrogenase, mitochondrial precursor, putative	0.001	0.0098	0.0098
Echinococcus granulosus	rhodopsin orphan GPCR	0.0029	0.0802	0.0799
Loa Loa (eye worm)	D-ets-2 protein	0.0012	0.016	0.0156
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Leishmania major	DNA polymerase kappa, putative	0.0022	0.0543	0.5972
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0029	0.0802	0.0799
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Onchocerca volvulus		0.0029	0.0802	0.1159
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0029	0.0802	0.0799
Echinococcus multilocularis	neuropeptide receptor	0.0029	0.0802	0.0799
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0008	0.0007	0.0004
Schistosoma mansoni	beta-14-galactosyltransferase 34-related	0.0016	0.0302	0.0318
Schistosoma mansoni	biogenic amine receptor	0.0029	0.0802	0.0857
Schistosoma mansoni	neuropeptide receptor	0.0029	0.0802	0.0857
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0008	0.0007	0.0007
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0008	0.0007	0.0004
Schistosoma mansoni	opsin-like receptor	0.0029	0.0802	0.0857
Onchocerca volvulus		0.0188	0.6864	1
Echinococcus multilocularis	Ataxin 2, N terminal,domain containing protein	0.0009	0.0043	0.004
Loa Loa (eye worm)	ets-domain-containing protein	0.0012	0.016	0.0156
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0029	0.0802	0.0802
Mycobacterium ulcerans	DNA polymerase IV	0.0022	0.0543	1
Echinococcus granulosus	biogenic amine 5HT receptor	0.0029	0.0802	0.0799
Loa Loa (eye worm)	hypothetical protein	0.0012	0.016	0.0156
Brugia malayi	hypothetical protein	0.0029	0.0802	0.0802
Brugia malayi	steroid hormone receptor	0.0008	0.0007	0.0007
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0029	0.0802	0.1159
Schistosoma mansoni	beta-14-galactosyltransferase	0.0146	0.527	0.5677
Trypanosoma brucei	PAB1-binding protein , putative	0.002	0.0462	0.4894
Echinococcus granulosus	G protein coupled receptor 139	0.0029	0.0802	0.0799
Echinococcus granulosus	rhodopsin orphan GPCR	0.0029	0.0802	0.0799
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0029	0.0802	0.0799
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0008	0.0007	0.0004
Schistosoma mansoni	hypothetical protein	0.0029	0.0802	0.0857
Brugia malayi	neuropeptide F receptor	0.0029	0.0802	0.0802
Echinococcus multilocularis	neuropeptide Y receptor	0.0029	0.0802	0.0799
Schistosoma mansoni	cpg binding protein	0.0024	0.0618	0.0659
Schistosoma mansoni	DNA polymerase eta	0.0022	0.0543	0.0578
Echinococcus granulosus	histone lysine methyltransferase setb	0.0024	0.0621	0.0618
Plasmodium vivax	glutathione reductase, putative	0.003	0.0843	1
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0008	0.0007	0.0004
Echinococcus granulosus	serotonin receptor	0.0029	0.0802	0.0799
Brugia malayi	Pre-SET motif family protein	0.0165	0.5997	0.5997
Echinococcus multilocularis	Ribosomal protein L34a	0.0108	0.3808	0.3805
Brugia malayi	G-protein coupled receptor	0.0029	0.0802	0.0802
Echinococcus granulosus	dihydrolipoamide dehydrogenase	0.001	0.0098	0.0094
Brugia malayi	Fli-1 protein	0.0251	0.9277	0.9277
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0024	0.0621	0.0663
Mycobacterium tuberculosis	Probable oxidoreductase	0.0076	0.2595	0.7854
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0029	0.0802	0.0799
Echinococcus multilocularis	FTZ F1 alpha	0.0008	0.0007	0.0004
Brugia malayi	photoreceptor-specific nuclear receptor	0.0008	0.0007	0.0007
Brugia malayi	neuropeptide F receptor	0.0029	0.0802	0.0802
Mycobacterium tuberculosis	Probable membrane NADH dehydrogenase NdhA	0.0068	0.2304	0.6941
Echinococcus multilocularis	ETS transcription factor Elf 2	0.0012	0.016	0.0156
Wolbachia endosymbiont of Brugia malayi	dihydrolipoamide dehydrogenase E3 component	0.001	0.0098	0.5
Wolbachia endosymbiont of Brugia malayi	dihydrolipoamide dehydrogenase E3 component	0.001	0.0098	0.5
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0024	0.0621	0.0663
Schistosoma mansoni	hypothetical protein	0.0029	0.0802	0.0857
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0008	0.0007	0.0004
Echinococcus multilocularis	Metazoa galactosyltransferase	0.0123	0.4407	0.4405
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0022	0.0543	0.5972
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0008	0.0007	0.0007
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Onchocerca volvulus		0.0029	0.0802	0.1159
Loa Loa (eye worm)	hypothetical protein	0.0172	0.6283	0.6281
Brugia malayi	nuclear hormone receptor	0.0008	0.0007	0.0007
Loa Loa (eye worm)	hypothetical protein	0.0008	0.0007	0.0004
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0029	0.0802	0.0799
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Loa Loa (eye worm)	D-ets-4 DNA binding domain-containing protein	0.0083	0.2856	0.2853
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0029	0.0802	0.0857
Loa Loa (eye worm)	hypothetical protein	0.0008	0.0007	0.0004
Brugia malayi	beta-1,4-galactosyltransferase VII	0.0038	0.1165	0.1165
Plasmodium vivax	SET domain protein, putative	0.0024	0.0621	0.7027
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0008	0.0007	0.0004
Echinococcus multilocularis	beta 1,4 N acetylgalactosaminyltransferase	0.0038	0.1165	0.1162
Schistosoma mansoni	cpg binding protein	0.0024	0.0618	0.0659
Mycobacterium ulcerans	DNA polymerase IV	0.0022	0.0543	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0008	0.0007	0.0004
Brugia malayi	ecdysteroid receptor	0.0008	0.0007	0.0007
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.0024	0.0621	0.0663
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0044	0.1376	1
Mycobacterium leprae	DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE	0.0076	0.2595	1
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Loa Loa (eye worm)	hypothetical protein	0.0008	0.0007	0.0004
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0543	0.5972
Brugia malayi	ImpB/MucB/SamB family protein	0.0022	0.0543	0.0543
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0029	0.0802	0.0857
Trichomonas vaginalis	set domain proteins, putative	0.0188	0.6864	1
Brugia malayi	Ets-domain containing protein	0.0012	0.016	0.016
Schistosoma mansoni	biogenic amine receptor	0.0029	0.0802	0.0857
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0029	0.0802	0.0799
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Echinococcus multilocularis	serotonin receptor	0.0029	0.0802	0.0799
Loa Loa (eye worm)	hypothetical protein	0.0008	0.0007	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0029	0.0802	0.0799
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0029	0.0802	0.0802
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0029	0.0802	0.0799
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0029	0.0802	0.0857
Brugia malayi	Nuclear hormone receptor-like 1	0.0008	0.0007	0.0007
Schistosoma mansoni	opsin-like receptor	0.0029	0.0802	0.0857
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0543	0.5972
Echinococcus granulosus	beta 14 N acetylgalactosaminyltransferase	0.0038	0.1165	0.1162
Onchocerca volvulus		0.0029	0.0802	0.1159
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0029	0.0802	0.0857
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0029	0.0802	0.0799
Chlamydia trachomatis	dihydrolipoyl dehydrogenase	0.001	0.0098	0.5
Brugia malayi	hypothetical protein	0.0029	0.0802	0.0802
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0008	0.0007	0.0004
Brugia malayi	hypothetical protein	0.0172	0.6283	0.6283
Brugia malayi	glutathione reductase	0.003	0.0843	0.0843
Toxoplasma gondii	hypothetical protein	0.0038	0.1165	0.8345
Echinococcus granulosus	rhodopsin orphan GPCR	0.0029	0.0802	0.0799
Onchocerca volvulus		0.0029	0.0802	0.1159
Brugia malayi	ORL1-like opioid receptor	0.0029	0.0802	0.0802
Echinococcus granulosus	Ribosomal protein L34a	0.0108	0.3808	0.3805
Mycobacterium tuberculosis	NADPH-dependent mycothiol reductase Mtr	0.003	0.0843	0.2345
Mycobacterium tuberculosis	Probable NADH dehydrogenase Ndh	0.0068	0.2304	0.6941
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0543	0.5972
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0023	0.0569	0.0566
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0029	0.0802	0.0857
Trypanosoma brucei	DNA polymerase kappa, putative	0.0015	0.0282	0.2473
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0008	0.0007	0.0007
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Brugia malayi	AKH receptor	0.0029	0.0802	0.0802
Echinococcus granulosus	Ataxin 2 N terminaldomain containing protein	0.0009	0.0043	0.004
Echinococcus granulosus	rhodopsin orphan GPCR	0.0029	0.0802	0.0799
Echinococcus multilocularis	ets variant gene 4	0.0012	0.016	0.0156
Echinococcus granulosus	7tm_1 domain containing protein	0.0029	0.0802	0.0799
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Loa Loa (eye worm)	TYRA-2 protein	0.0029	0.0802	0.0799
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0165	0.5997	0.5996
Trypanosoma cruzi	DNA polymerase kappa, putative	0.0022	0.0543	0.5972
Echinococcus multilocularis	dna polymerase kappa	0.0022	0.0543	0.054
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Schistosoma mansoni	opsin-like receptor	0.0029	0.0802	0.0857
Schistosoma mansoni	gabp alpha	0.0083	0.2856	0.3073
Brugia malayi	hypothetical protein	0.0029	0.0802	0.0802
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0094	0.3277	1
Trypanosoma cruzi	trypanothione reductase, putative	0.003	0.0843	1
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0008	0.0007	0.0007
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0008	0.0007	0.0007
Treponema pallidum	NADH oxidase	0.001	0.0098	0.5
Loa Loa (eye worm)	neuropeptide F receptor	0.0029	0.0802	0.0799
Trypanosoma brucei	unspecified product	0.0015	0.0282	0.2473
Loa Loa (eye worm)	galactosyltransferase	0.0146	0.527	0.5268
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0008	0.0007	0.0004
Echinococcus granulosus	beta 14 galactosyltransferase 7	0.0038	0.1165	0.1162
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0029	0.0802	0.0857
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0029	0.0802	0.0799
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0029	0.0802	0.0857
Brugia malayi	sulfakinin receptor protein	0.0029	0.0802	0.0802
Echinococcus granulosus	cpg binding protein	0.0024	0.0618	0.0615
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0029	0.0802	0.0802
Echinococcus multilocularis	ETS domain containing protein Elk 1	0.0012	0.016	0.0156
Echinococcus granulosus	dna polymerase eta	0.0022	0.0543	0.054
Trypanosoma brucei	DNA polymerase IV, putative	0.0022	0.0543	0.5972
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0008	0.0007	0.0004
Echinococcus multilocularis	thioredoxin glutathione reductase	0.003	0.0858	0.0855
Toxoplasma gondii	glycosyl transferase	0.0016	0.0302	0.1596
Loa Loa (eye worm)	D-ets-4 DNA binding domain-containing protein	0.0012	0.016	0.0156
Echinococcus granulosus	neuropeptide s receptor	0.0029	0.0802	0.0799
Echinococcus multilocularis	orexin receptor type 2	0.0029	0.0802	0.0799
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Echinococcus granulosus	ecdysone induced protein 78C	0.0008	0.0007	0.0004
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0029	0.0802	0.1159
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Echinococcus multilocularis	g protein coupled receptor	0.0029	0.0802	0.0799
Onchocerca volvulus		0.0029	0.0802	0.1159
Mycobacterium tuberculosis	Probable reductase	0.0068	0.2304	0.6941
Schistosoma mansoni	ets-related	0.0012	0.016	0.0165
Onchocerca volvulus		0.0029	0.0802	0.1159
Echinococcus granulosus	ETS transcription factor Elf 1	0.0012	0.016	0.0156
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Brugia malayi	Steroid receptor seven-up type 2	0.0008	0.0007	0.0007
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0023	0.0568	0.0565
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0029	0.0802	0.0857
Echinococcus multilocularis	ewsr:fli fusion protein type	0.0012	0.016	0.0156
Echinococcus multilocularis	ecdysone induced protein 78C	0.0008	0.0007	0.0004
Brugia malayi	nuclear receptor NHR-88	0.0008	0.0007	0.0007
Mycobacterium tuberculosis	Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB	0.0068	0.2304	0.6941
Loa Loa (eye worm)	hypothetical protein	0.0024	0.0621	0.0618
Echinococcus multilocularis	dro:myosuppressin receptor	0.0029	0.0802	0.0799
Echinococcus granulosus	g-protein coupled receptor	0.0029	0.0802	0.0799
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0029	0.0802	0.0857
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0008	0.0007	0.0007
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0008	0.0007	0.0004
Brugia malayi	G protein-coupled receptor	0.0029	0.0802	0.0802
Echinococcus multilocularis	cpg binding protein	0.0024	0.0618	0.0615
Loa Loa (eye worm)	hypothetical protein	0.0008	0.0007	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Echinococcus granulosus	neuropeptide Y receptor	0.0029	0.0802	0.0799
Schistosoma mansoni	neuropeptide F-like receptor	0.0029	0.0802	0.0857
Plasmodium falciparum	ataxin-2 like protein, putative	0.002	0.0462	0.4894
Echinococcus granulosus	ETS transcription factor Elf 5	0.0012	0.016	0.0156
Brugia malayi	putative neuropeptide receptor	0.0029	0.0802	0.0802
Brugia malayi	hypothetical protein	0.002	0.0462	0.0462
Schistosoma mansoni	beta-14-galactosyltransferase	0.0038	0.1165	0.1249
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0029	0.0802	0.0799
Schistosoma mansoni	amine GPCR	0.0029	0.0802	0.0857
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0029	0.0802	0.0799
Schistosoma mansoni	amine GPCR	0.0029	0.0802	0.0857
Schistosoma mansoni	biogenic amine receptor	0.0029	0.0802	0.0857
Loa Loa (eye worm)	hypothetical protein	0.002	0.0462	0.0459
Schistosoma mansoni	dihydrolipoamide dehydrogenase	0.001	0.0098	0.0098
Loa Loa (eye worm)	hypothetical protein	0.027	1	1
Trypanosoma brucei	DNA polymerase kappa, putative	0.0015	0.0282	0.2473
Schistosoma mansoni	ets	0.0012	0.016	0.0165
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0029	0.0802	0.0799
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0543	0.5972
Echinococcus granulosus	tm gpcr rhodopsin	0.0029	0.0802	0.0799
Echinococcus granulosus	g protein coupled receptor	0.0029	0.0802	0.0799
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0029	0.0802	0.0799
Onchocerca volvulus		0.0029	0.0802	0.1159
Trypanosoma brucei	unspecified product	0.0022	0.0543	0.5972
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0024	0.0621	0.0618
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0008	0.0007	0.0007
Schistosoma mansoni	myosin xvIII	0.0029	0.0802	0.0857
Echinococcus multilocularis	GA binding protein alpha chain	0.0083	0.2856	0.2853
Schistosoma mansoni	hypothetical protein	0.0023	0.0565	0.0602
Echinococcus multilocularis	dna polymerase eta	0.0022	0.0543	0.054
Echinococcus granulosus	neuropeptide receptor	0.0029	0.0802	0.0799
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0029	0.0802	0.0799
Echinococcus granulosus	biogenic amine 5HT receptor	0.0029	0.0802	0.0799
Schistosoma mansoni	beta-14-galactosyltransferase	0.0038	0.1165	0.1249
Echinococcus granulosus	dna polymerase kappa	0.0022	0.0543	0.054
Echinococcus multilocularis	terminal deoxycytidyl transferase rev1	0.0022	0.0543	0.054
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0029	0.0802	0.0799
Leishmania major	DNA polymerase eta, putative	0.0022	0.0543	0.5972
Brugia malayi	G protein-coupled receptor F59B2.13	0.0029	0.0802	0.0802
Trypanosoma brucei	DNA polymerase kappa, putative	0.0022	0.0543	0.5972
Echinococcus multilocularis	neuropeptide receptor	0.0029	0.0802	0.0799
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0029	0.0802	0.0799
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0008	0.0007	0.0004
Onchocerca volvulus		0.0029	0.0802	0.1159
Echinococcus granulosus	terminal deoxycytidyl transferase rev1	0.0022	0.0543	0.054
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0029	0.0802	0.0857
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0029	0.0802	0.0799
Schistosoma mansoni	terminal deoxycytidyl transferase	0.0022	0.0543	0.0578
Onchocerca volvulus		0.0029	0.0802	0.1159
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0029	0.0802	0.0857
Onchocerca volvulus		0.0029	0.0802	0.1159
Plasmodium falciparum	thioredoxin reductase	0.003	0.0843	1
Mycobacterium tuberculosis	Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras	0.0076	0.2595	0.7854
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0008	0.0007	0.0007
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0029	0.0802	0.0799
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0029	0.0802	0.0799
Schistosoma mansoni	beta-14-galactosyltransferase	0.0038	0.1165	0.1249
Loa Loa (eye worm)	G-protein coupled receptor	0.0029	0.0802	0.0799
Echinococcus multilocularis	protein C ets 2	0.0012	0.016	0.0156
Onchocerca volvulus		0.0029	0.0802	0.1159
Echinococcus granulosus	somatostatin receptor	0.0029	0.0802	0.0799
Loa Loa (eye worm)	UDP-Galactose:b-N-acetylglucosamine b1,4-galactosyltransferase 4	0.0038	0.1165	0.1162
Schistosoma mansoni	hypothetical protein	0.0012	0.016	0.0165
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0029	0.0802	0.0857
Schistosoma mansoni	n-acetylgalactosaminyltransferase	0.0016	0.0302	0.0318
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0802	0.0799
Schistosoma mansoni	neuropeptide receptor	0.0029	0.0802	0.0857
Brugia malayi	hypothetical protein	0.0013	0.0193	0.0193
Brugia malayi	Serotonin receptor	0.0029	0.0802	0.0802
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0029	0.0802	0.0799
Loa Loa (eye worm)	glutathione reductase	0.003	0.0843	0.084
Schistosoma mansoni	survival motor neuron protein	0.0055	0.1803	0.1937
Schistosoma mansoni	neuropeptide f receptor 76f	0.0029	0.0802	0.0857
Echinococcus multilocularis	Metazoa galactosyltransferase	0.0146	0.527	0.5268
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0029	0.0802	0.0857
Loa Loa (eye worm)	hypothetical protein	0.0071	0.2399	0.2396
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0029	0.0802	0.0857
Loa Loa (eye worm)	melatonin receptor type 1A	0.0029	0.0802	0.0799
Loa Loa (eye worm)	steroid hormone receptor	0.0008	0.0007	0.0004
Brugia malayi	hypothetical protein	0.0029	0.0802	0.0802
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0008	0.0007	0.0004
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.0024	0.0621	0.4097
Brugia malayi	hypothetical protein	0.0029	0.0802	0.0802
Schistosoma mansoni	beta-14-galactosyltransferase 34-related	0.0038	0.1165	0.1249
Brugia malayi	Galactosyltransferase family protein	0.0038	0.1165	0.1165
Brugia malayi	ImpB/MucB/SamB family protein	0.0022	0.0543	0.0543

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL3489092

Bibliographic References

No literature references available for this target.

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Detailed information for compound 2069422