Detailed information for compound 2071782

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 331.436 | Formula: C16H21N5OS
  • H donors: 1 H acceptors: 3 LogP: 1.66 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN1CCN(CC1)c1nccc(c1)CNC(=O)c1scnc1C
  • InChi: 1S/C16H21N5OS/c1-12-15(23-11-19-12)16(22)18-10-13-3-4-17-14(9-13)21-7-5-20(2)6-8-21/h3-4,9,11H,5-8,10H2,1-2H3,(H,18,22)
  • InChiKey: GKISNKSPOWHWSE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0015 0.0239 0.0357
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0006 0.0052 0.0053
Schistosoma mansoni regulator of G protein signaling 0.0006 0.0052 0.0053
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0005 0.0022 0.0112
Echinococcus multilocularis regulator of G protein signaling 0.0006 0.0052 0.0053
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0006 0.0052 0.2163
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0015 0.0239 0.928
Schistosoma mansoni regulator of G protein signaling 0.0006 0.0052 0.0053
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0005 0.0032 0.0516
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0026 0.0473 0.2436
Trypanosoma brucei trypanothione reductase 0.0016 0.0256 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0155 0.6498
Giardia lamblia DNA repair protein RAD52 0.0091 0.1883 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0239 1
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0005 0.0032 0.0516
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0006 0.0052 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0239 1
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0005 0.0032 0.0516
Leishmania major phosphatidylinositol 3-kinase, putative 0.0005 0.0022 0.0112
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0089 0.3713
Brugia malayi glutathione reductase 0.0016 0.0256 0.0415
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0005 0.0032 0.016
Schistosoma mansoni vesicular acetylcholine transporter 0.0287 0.616 1
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0036 0.0695 0.8856
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0172 0.7204
Schistosoma mansoni z-protein (S1r protein) 0.0006 0.0052 0.0053
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0005 0.0032 0.0516
Echinococcus multilocularis expressed protein 0.0125 0.2619 0.4233
Echinococcus granulosus geminin 0.0044 0.0873 0.1391
Trichomonas vaginalis glutathione reductase, putative 0.0005 0.0032 0.1316
Schistosoma mansoni calcium-activated potassium channel 0.0068 0.1385 0.2224
Trichomonas vaginalis PIKK family atypical protein kinase 0.0005 0.0022 0.0916
Echinococcus granulosus small conductance calcium activated potassium 0.0086 0.1772 0.2854
Mycobacterium tuberculosis Probable oxidoreductase 0.004 0.0782 1
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0052 0.2163
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0015 0.0239 0.928
Echinococcus granulosus regulator of G protein signaling 3 0.0006 0.0052 0.0053
Loa Loa (eye worm) PXA domain-containing protein 0.0006 0.0052 0.0032
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0107 0.4499
Trypanosoma cruzi trypanothione reductase, putative 0.0005 0.0032 0.0516
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0005 0.0032 0.0516
Trypanosoma cruzi cytochrome P450, putative 0.0005 0.0028 0.0348
Brugia malayi Thioredoxin reductase 0.0016 0.0256 0.0415
Plasmodium vivax thioredoxin reductase, putative 0.0016 0.0256 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0088 0.3702
Echinococcus granulosus intermediate filament protein 0.0007 0.0066 0.0075
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0006 0.0052 0.0032
Echinococcus granulosus vesicular acetylcholine transporter 0.0287 0.616 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0009 0.0102 0.0083
Loa Loa (eye worm) phosphatidylinositol 3 0.0005 0.0022 0.0003
Loa Loa (eye worm) glutathione reductase 0.0016 0.0256 0.0237
Schistosoma mansoni hypothetical protein 0.0044 0.0873 0.1391
Schistosoma mansoni axis inhibition protein axin 0.0006 0.0052 0.0053
Echinococcus granulosus thioredoxin glutathione reductase 0.0016 0.0256 0.0385
Loa Loa (eye worm) hypothetical protein 0.0006 0.0052 0.0032
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0239 0.0387
Echinococcus granulosus axis inhibition protein axin 0.0006 0.0052 0.0053
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0006 0.0052 0.0032
Loa Loa (eye worm) hypothetical protein 0.0006 0.0052 0.0032
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.004 0.0782 1
Leishmania major cytochrome p450-like protein 0.0005 0.0028 0.0348
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0007 0.0067 0.201
Brugia malayi Regulator of G protein signaling domain containing protein 0.0006 0.0052 0.0084
Schistosoma mansoni hypothetical protein 0.0086 0.1772 0.2854
Loa Loa (eye worm) hypothetical protein 0.0086 0.1772 0.1756
Loa Loa (eye worm) thioredoxin reductase 0.0016 0.0256 0.0237
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0088 0.3702
Echinococcus multilocularis axis inhibition protein axin 0.0006 0.0052 0.0053
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0005 0.0032 0.0516
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0005 0.0032 0.0516
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0015 0.0239 0.0357
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0005 0.0032 0.0516
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0005 0.0032 0.0516
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0172 0.7204
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0124 0.5205
Trypanosoma cruzi target of rapamycin kinase 3 0.0012 0.0172 0.6469
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0005 0.0028 0.675
Echinococcus granulosus regulator of G protein signaling 7 0.0006 0.0052 0.0053
Trichomonas vaginalis ap endonuclease, putative 0.0005 0.0019 0.0805
Mycobacterium tuberculosis Probable dehydrogenase 0.0036 0.0695 0.8856
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0005 0.0032 0.0516
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0172 0.7204
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0005 0.0032 0.0051
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0005 0.0032 0.0516
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0005 0.0022 0.0112
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0005 0.0022 0.0004
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0005 0.0032 0.0516
Schistosoma mansoni calcium-activated potassium channel 0.0086 0.1772 0.2854
Trypanosoma brucei cytochrome P450, putative 0.0005 0.0028 0.0348
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0052 0.2163
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0005 0.0032 0.0516
Echinococcus multilocularis lamin 0.0007 0.0066 0.0075
Entamoeba histolytica hypothetical protein 0.0026 0.0473 0.2436
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0239 1
Schistosoma mansoni serine/threonine protein kinase 0.0006 0.0052 0.0053
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0005 0.0022 0.0112
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0006 0.0052 0.0053
Plasmodium vivax glutathione reductase, putative 0.0016 0.0256 1
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0005 0.0022 0.0004
Echinococcus multilocularis regulator of G protein signaling 3 0.0006 0.0052 0.0053
Entamoeba histolytica hypothetical protein 0.0006 0.0052 0.0174
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0036 0.0695 0.8856
Trichomonas vaginalis PIKK family atypical protein kinase 0.001 0.0131 0.5501
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0005 0.0022 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0052 0.2163
Toxoplasma gondii NADPH-glutathione reductase 0.0005 0.0032 0.0516
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0005 0.0032 1
Brugia malayi vesicular acetylcholine transporter unc-17 0.0287 0.616 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.004 0.0782 1
Plasmodium falciparum glutathione reductase 0.0005 0.0032 0.0516
Entamoeba histolytica hypothetical protein 0.0006 0.0052 0.0174
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0155 0.6498
Schistosoma mansoni intermediate filament proteins 0.0007 0.0066 0.0075
Brugia malayi hypothetical protein 0.0006 0.0052 0.0084
Loa Loa (eye worm) hypothetical protein 0.0464 1 1
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0005 0.0022 0.0112
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0005 0.0032 0.0516
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0172 0.7204
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0015 0.0239 0.928
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0088 0.3702
Loa Loa (eye worm) hypothetical protein 0.0032 0.0609 0.0591
Brugia malayi A-kinase anchor protein 10, precursor 0.0006 0.0052 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0105 0.4418
Echinococcus multilocularis thioredoxin glutathione reductase 0.0016 0.0256 0.0385
Schistosoma mansoni lamin 0.0007 0.0066 0.0075
Loa Loa (eye worm) hypothetical protein 0.0006 0.0052 0.0032
Brugia malayi exodeoxyribonuclease III family protein 0.0005 0.0019 0.0031
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0012 0.0172 0.6469
Brugia malayi Cytochrome P450 family protein 0.0005 0.0028 0.0045
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0007 0.0066 0.0046
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0005 0.0032 0.0516
Brugia malayi regulator of G-protein signaling egl-10 0.0006 0.0052 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0155 0.6498
Toxoplasma gondii target of rapamycin (TOR), putative 0.0011 0.0155 0.5746
Schistosoma mansoni regulator of G protein signaling 0.0006 0.0052 0.0053
Echinococcus granulosus lamin 0.0007 0.0066 0.0075
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0005 0.0032 1
Mycobacterium tuberculosis Probable reductase 0.0036 0.0695 0.8856
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0239 0.022
Toxoplasma gondii thioredoxin reductase 0.0016 0.0256 1
Schistosoma mansoni regulator of G protein signaling 0.0006 0.0052 0.0053
Schistosoma mansoni regulator of G protein signaling 0.0006 0.0052 0.0053
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0005 0.0032 0.0516
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0036 0.0695 0.8856
Brugia malayi Cytochrome P450 family protein 0.0009 0.0102 0.0166
Loa Loa (eye worm) hypothetical protein 0.0106 0.2213 0.2198
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0006 0.0052 0.0053
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0006 0.0048 0.1216
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0015 0.0239 0.1176
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0005 0.0032 0.0516
Schistosoma mansoni serine/threonine protein kinase 0.0006 0.0052 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0052 0.2163
Entamoeba histolytica hypothetical protein 0.0006 0.0052 0.0174
Echinococcus multilocularis regulator of G protein signaling 7 0.0006 0.0052 0.0053
Loa Loa (eye worm) hypothetical protein 0.0007 0.0066 0.0046
Treponema pallidum NADH oxidase 0.0005 0.0032 1
Echinococcus granulosus regulator of G protein signaling 3 0.0006 0.0052 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0105 0.4418
Echinococcus granulosus beta-adrenergic receptor kinase 0.0006 0.0052 0.0053
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0256 1
Brugia malayi Intermediate filament tail domain containing protein 0.0007 0.0066 0.0106
Echinococcus multilocularis musashi 0.0007 0.0066 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0089 0.3713
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0015 0.0239 0.928
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0005 0.0022 0.0036
Loa Loa (eye worm) hypothetical protein 0.0006 0.0052 0.0032
Echinococcus multilocularis axis inhibition protein axin 0.0006 0.0052 0.0053
Loa Loa (eye worm) intermediate filament protein 0.0007 0.0066 0.0046
Loa Loa (eye worm) hypothetical protein 0.0014 0.0224 0.0205
Brugia malayi PXA domain containing protein 0.0006 0.0052 0.0084
Loa Loa (eye worm) cytochrome P450 family protein 0.0005 0.0028 0.0008
Brugia malayi hypothetical protein 0.0006 0.0052 0.0084
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0172 0.7204
Trichomonas vaginalis PIKK family atypical protein kinase 0.0005 0.0022 0.0916
Trypanosoma cruzi cytochrome P450, putative 0.0005 0.0028 0.0348
Schistosoma mansoni lamin 0.0007 0.0066 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0052 0.2163
Echinococcus multilocularis geminin 0.0044 0.0873 0.1391
Echinococcus multilocularis Regulator of G protein signaling 20 0.0006 0.0052 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0107 0.4499
Giardia lamblia GTOR 0.0015 0.0239 0.1176
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0005 0.0032 0.0516
Echinococcus multilocularis lamin dm0 0.0007 0.0066 0.0075
Brugia malayi regulator of G-protein signaling rgs-7 0.0006 0.0052 0.0084
Loa Loa (eye worm) hypothetical protein 0.0006 0.0052 0.0032
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0015 0.0239 0.0357
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0006 0.0052 0.0084
Plasmodium falciparum thioredoxin reductase 0.0016 0.0256 1
Brugia malayi hypothetical protein 0.0041 0.0795 0.1291
Loa Loa (eye worm) hypothetical protein 0.0036 0.0689 0.0671
Giardia lamblia NADH oxidase lateral transfer candidate 0.0005 0.0032 0.0065
Plasmodium falciparum glutathione reductase 0.0016 0.0256 1
Echinococcus granulosus regulator of G protein signaling 7 0.0006 0.0052 0.0053
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.004 0.0782 1
Brugia malayi PXA domain containing protein 0.0006 0.0052 0.0084
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0015 0.0239 0.928
Echinococcus granulosus lamin dm0 0.0007 0.0066 0.0075
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0155 0.6498
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0015 0.0239 0.928
Echinococcus multilocularis vesicular acetylcholine transporter 0.0287 0.616 1
Loa Loa (eye worm) vesicular acetylcholine transporter unc-17 0.0287 0.616 0.6153
Plasmodium falciparum thioredoxin reductase 0.0005 0.0032 0.0516
Loa Loa (eye worm) CYP4Cod1 0.0005 0.0028 0.0008
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0005 0.0032 0.0516
Echinococcus granulosus Regulator of G protein signaling 20 0.0006 0.0052 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0005 0.0022 0.0916
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0005 0.0032 1
Echinococcus multilocularis beta adrenergic receptor kinase 0.0006 0.0052 0.0053
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0091 0.1883 1
Brugia malayi Regulator of G protein signaling domain containing protein 0.0006 0.0052 0.0084
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0005 0.0022 0.0112
Trichomonas vaginalis mercuric reductase, putative 0.0005 0.0032 0.1316
Loa Loa (eye worm) hypothetical protein 0.0007 0.0063 0.0044
Leishmania major trypanothione reductase 0.0016 0.0256 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0016 0.0256 0.3097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0191 0.8002
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0006 0.0052 0.0053
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0005 0.0032 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0005 0.0028 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0005 0.0022 0.0916
Loa Loa (eye worm) hypothetical protein 0.0006 0.0052 0.0032
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0005 0.0032 1
Onchocerca volvulus Vesicular acetylcholine transporter homolog 0.0287 0.616 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0089 0.3713
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0005 0.0032 0.0516
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0005 0.0032 0.002
Echinococcus granulosus axis inhibition protein axin 0.0006 0.0052 0.0053
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0015 0.0239 0.1176
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0155 0.6498
Echinococcus multilocularis small conductance calcium activated potassium 0.0086 0.1772 0.2854
Trichomonas vaginalis ap endonuclease, putative 0.0005 0.0019 0.0805
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0005 0.0032 0.0516
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0052 0.2163
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0006 0.0052 0.0032
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0005 0.0032 0.5
Echinococcus granulosus expressed protein 0.0125 0.2619 0.4233
Echinococcus multilocularis regulator of G protein signaling 3 0.0006 0.0052 0.0053
Brugia malayi Cytochrome P450 family protein 0.0005 0.0028 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0009 0.0107 0.4499
Trichomonas vaginalis PIKK family atypical protein kinase 0.0005 0.0022 0.0916
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0005 0.0032 0.002
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0012 0.0172 0.6469
Loa Loa (eye worm) RGS-3 protein 0.0006 0.0052 0.0032
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0036 0.0695 0.8856
Brugia malayi intermediate filament protein 0.0007 0.0066 0.0106
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0005 0.0032 0.002
Echinococcus multilocularis regulator of G protein signaling 7 0.0006 0.0052 0.0053
Schistosoma mansoni hypothetical protein 0.0044 0.0873 0.1391
Trichomonas vaginalis PIKK family atypical protein kinase 0.0008 0.0089 0.3713
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0155 0.6498
Schistosoma mansoni axis inhibition protein axin 0.0006 0.0052 0.0053
Schistosoma mansoni serine/threonine protein kinase 0.0006 0.0052 0.0053
Trichomonas vaginalis PIKK family atypical protein kinase 0.0011 0.0155 0.6498

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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