Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | amine transporter, putative | 0.0121 | 0.1393 | 0.5 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0121 | 0.1393 | 0.1393 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0121 | 0.1393 | 0.1393 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0198 | 0.2501 | 0.2501 |
Echinococcus granulosus | fibroblast growth factor receptor 4 | 0.0121 | 0.1391 | 0.1391 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0053 | 0.0053 |
Schistosoma mansoni | nephrin | 0.0032 | 0.0094 | 0.0094 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0121 | 0.1393 | 0.1393 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0121 | 0.1393 | 0.1393 |
Echinococcus granulosus | basic fibroblast growth factor receptor 1 A | 0.0121 | 0.1391 | 0.1391 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.0175 | 0.2175 | 0.0908 |
Schistosoma mansoni | tyrosine kinase | 0.0121 | 0.1391 | 0.1391 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.0121 | 0.1393 | 0.1393 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.0121 | 0.1393 | 0.1393 |
Toxoplasma gondii | hypothetical protein | 0.0121 | 0.1393 | 0.5 |
Loa Loa (eye worm) | serotonin transporter b | 0.0716 | 1 | 1 |
Onchocerca volvulus | 0.0716 | 1 | 1 | |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0198 | 0.2501 | 0.2501 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0716 | 1 | 1 |
Schistosoma mansoni | cell adhesion molecule | 0.0029 | 0.0053 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0716 | 1 | 1 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0121 | 0.1393 | 0.1393 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0121 | 0.1393 | 0.1393 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0121 | 0.1393 | 0.1393 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0716 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.1393 | 0.1393 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0121 | 0.1393 | 0.1393 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.0121 | 0.1393 | 0.1393 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0716 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.1393 | 0.1393 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.1393 | 0.1393 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0121 | 0.1393 | 0.1393 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0128 | 0.1485 | 0.1485 |
Echinococcus granulosus | serotonin transporter | 0.0716 | 1 | 1 |
Echinococcus granulosus | neuroglian | 0.0032 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.1393 | 0.1393 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0121 | 0.1393 | 0.1393 |
Plasmodium vivax | hypothetical protein, conserved | 0.0121 | 0.1393 | 0.5 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0121 | 0.1393 | 0.1393 |
Echinococcus multilocularis | roundabout 2 | 0.0035 | 0.0147 | 0.0147 |
Echinococcus multilocularis | zinc finger transcription factor gli2 | 0.0375 | 0.5065 | 0.5065 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.0121 | 0.1393 | 0.1393 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0121 | 0.1393 | 0.1393 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0121 | 0.1393 | 0.5 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0121 | 0.1393 | 0.1393 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0147 | 0.0147 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0121 | 0.1393 | 0.1393 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0121 | 0.1393 | 0.1393 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.1393 | 0.1393 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.1393 | 0.1393 |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.0121 | 0.1393 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0147 | 0.0147 |
Echinococcus granulosus | twitchin | 0.0032 | 0.0094 | 0.0094 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0121 | 0.1393 | 0.1393 |
Brugia malayi | Zinc finger, C2H2 type family protein | 0.0375 | 0.5065 | 0.5065 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0121 | 0.1393 | 0.1393 |
Loa Loa (eye worm) | hypothetical protein | 0.0716 | 1 | 1 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0029 | 0.0053 | 0.0053 |
Loa Loa (eye worm) | zinc finger protein | 0.0375 | 0.5065 | 0.5065 |
Loa Loa (eye worm) | TK protein kinase | 0.0128 | 0.1485 | 0.1485 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0121 | 0.1393 | 0.1393 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0121 | 0.1393 | 0.1393 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0121 | 0.1393 | 0.1393 |
Echinococcus multilocularis | neuroglian | 0.0032 | 0.0094 | 0.0094 |
Onchocerca volvulus | 0.0167 | 0.2048 | 0.076 | |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0121 | 0.1393 | 0.1393 |
Loa Loa (eye worm) | hypothetical protein | 0.0716 | 1 | 1 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0121 | 0.1393 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.1393 | 0.1393 |
Echinococcus multilocularis | serotonin transporter | 0.0716 | 1 | 1 |
Plasmodium falciparum | amino acid transporter, putative | 0.0121 | 0.1393 | 0.5 |
Echinococcus granulosus | roundabout 2 | 0.0035 | 0.0147 | 0.0147 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0716 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0121 | 0.1393 | 0.1393 |
Echinococcus multilocularis | fibroblast growth factor receptor 4 | 0.0121 | 0.1391 | 0.1391 |
Echinococcus multilocularis | basic fibroblast growth factor receptor 1 A | 0.0121 | 0.1391 | 0.1391 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0716 | 1 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0121 | 0.1393 | 0.5 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0121 | 0.1393 | 0.1393 |
Echinococcus granulosus | zinc finger transcription factor gli2 | 0.0375 | 0.5065 | 0.5065 |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.0121 | 0.1393 | 0.1393 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0121 | 0.1393 | 0.5 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0121 | 0.1393 | 0.1393 |
Plasmodium falciparum | transporter, putative | 0.0121 | 0.1393 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.