Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0001 | 0.0015 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0001 | 0.0015 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.002 | 0.0002 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Entamoeba histolytica | cysteine protease, putative | 0.002 | 0.0002 | 0.0435 |
Echinococcus multilocularis | jun protein | 0.0094 | 0.0158 | 0.2102 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Treponema pallidum | penicillin-binding protein (pbp-1) | 0.0172 | 0.0324 | 1 |
Loa Loa (eye worm) | fibroinase | 0.002 | 0.0002 | 0.0026 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.002 | 0.0002 | 0.0026 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.002 | 0.0002 | 0.0026 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0094 | 0.0158 | 0.2102 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0376 | 0.0753 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.002 | 0.0002 | 0.0026 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.0122 | 0.0255 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0376 | 0.0753 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Mycobacterium ulcerans | class a beta-lactamase, BlaC | 0.475 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0001 | 0.0015 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0376 | 0.0753 | 0.0753 |
Toxoplasma gondii | ABC1 family protein | 0.0376 | 0.0753 | 1 |
Mycobacterium ulcerans | penicillin-binding membrane protein PbpB | 0.0172 | 0.0324 | 0.0324 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0001 | 0.0015 |
Mycobacterium ulcerans | penicillin-binding protein PbpA | 0.0172 | 0.0324 | 0.0324 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0001 | 0.0015 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0002 | 0.0026 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0001 | 0.0015 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0001 | 0.0015 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0001 | 0.0015 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0001 | 0.0015 |
Leishmania major | cathepsin L-like protease | 0.002 | 0.0002 | 0.0026 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0077 | 0.0122 | 0.162 |
Onchocerca volvulus | Cathepsin L homolog | 0.002 | 0.0002 | 0.0026 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.002 | 0.0001 | 0.0015 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Onchocerca volvulus | 0.0376 | 0.0753 | 1 | |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0376 | 0.0753 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0001 | 0.0015 |
Mycobacterium ulcerans | beta-lactamase | 0.0376 | 0.0753 | 0.0753 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0001 | 0.0015 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0001 | 0.0015 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0376 | 0.0753 | 0.0753 |
Loa Loa (eye worm) | cysteine protease | 0.002 | 0.0002 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0376 | 0.0753 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0376 | 0.0753 | 0.1576 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.0122 | 0.0255 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.002 | 0.0002 | 0.0026 |
Mycobacterium ulcerans | penicillin-binding lipoprotein | 0.0172 | 0.0324 | 0.0324 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.0122 | 0.0255 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0001 | 0.0015 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0001 | 0.0015 |
Treponema pallidum | penicillin-binding protein (pbp-2) | 0.0172 | 0.0324 | 1 |
Onchocerca volvulus | 0.0074 | 0.0116 | 0.1534 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0001 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0002 | 0.0026 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0001 | 0.0015 |
Mycobacterium tuberculosis | Probable penicillin-binding protein PbpA | 0.0172 | 0.0324 | 0.0324 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0001 | 0.0015 |
Leishmania major | cathepsin L-like protease | 0.002 | 0.0002 | 0.0026 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0001 | 0.0015 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0376 | 0.0753 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0376 | 0.0753 | 0.0753 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0376 | 0.0753 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.0122 | 0.0255 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.0122 | 0.0255 |
Mycobacterium leprae | Probable lipase LipE | 0.0376 | 0.0753 | 0.1576 |
Brugia malayi | hypothetical protein | 0.004 | 0.0045 | 0.0591 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0001 | 0.0015 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0001 | 0.0015 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0002 | 0.0026 |
Mycobacterium tuberculosis | Possible penicillin-binding lipoprotein | 0.0172 | 0.0324 | 0.0324 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0001 | 0.0015 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0045 | 1 |
Plasmodium vivax | vivapain-2 | 0.002 | 0.0002 | 0.0026 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.002 | 0.0001 | 0.0015 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.002 | 0.0002 | 0.0026 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.004 | 0.0045 | 0.0591 |
Loa Loa (eye worm) | beta-lactamase | 0.0376 | 0.0753 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0001 | 0.0015 |
Brugia malayi | beta-lactamase | 0.0376 | 0.0753 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0001 | 0.0015 |
Onchocerca volvulus | 0.002 | 0.0002 | 0.0026 | |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0001 | 0.0015 |
Onchocerca volvulus | 0.002 | 0.0002 | 0.0026 | |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0001 | 0.0015 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.002 | 0.0002 | 0.0026 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0376 | 0.0753 | 1 |
Plasmodium vivax | vivapain-2 | 0.002 | 0.0002 | 0.0026 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0002 | 0.0026 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0376 | 0.0753 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0001 | 0.0015 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.004 | 0.0045 | 0.0591 |
Leishmania major | cysteine peptidase A (CPA) | 0.002 | 0.0002 | 0.0026 |
Leishmania major | hypothetical protein, conserved | 0.0376 | 0.0753 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0001 | 0.0015 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.0122 | 0.0255 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Onchocerca volvulus | 0.002 | 0.0002 | 0.0026 | |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0001 | 0.0015 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.0122 | 0.0255 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Brugia malayi | hypothetical protein | 0.0074 | 0.0116 | 0.1534 |
Onchocerca volvulus | 0.002 | 0.0002 | 0.0026 | |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0001 | 0.0015 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0001 | 0.0015 |
Mycobacterium leprae | PROBABLE BIFUNCTIONAL MEMBRANE-ASSOCIATED PENICILLIN-BINDING PROTEIN 1A/1B PONA2 (MUREIN POLYMERASE) [INCLUDES: PENICILLIN-INSEN | 0.0172 | 0.0324 | 0.0677 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0045 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0001 | 0.0015 |
Echinococcus granulosus | jun protein | 0.0094 | 0.0158 | 0.2102 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0001 | 0.0015 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0002 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0001 | 0.0015 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0045 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0002 | 0.0026 |
Brugia malayi | Papain family cysteine protease containing protein | 0.002 | 0.0002 | 0.0026 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0376 | 0.0753 | 0.0753 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0376 | 0.0753 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0001 | 0.0015 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0001 | 0.0015 |
Leishmania major | cathepsin L-like protease | 0.002 | 0.0002 | 0.0026 |
Mycobacterium ulcerans | bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 | 0.0172 | 0.0324 | 0.0324 |
Mycobacterium leprae | PROBABLE BIFUNCTIONAL PENICILLIN-BINDING PROTEIN 1A/1B PONA1 (MUREIN POLYMERASE) (PBP1): PENICILLIN-INSENSITIVE TRANSGLYCOSYLASE | 0.0172 | 0.0324 | 0.0677 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0376 | 0.0753 | 0.1576 |
Giardia lamblia | Hydroxyacylglutathione hydrolase | 0.0019 | 0 | 0.5 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0061 | 0.0087 | 0.1158 |
Echinococcus granulosus | cathepsin l1 | 0.002 | 0.0002 | 0.0026 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.0122 | 0.0255 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0001 | 0.0015 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0376 | 0.0753 | 0.0753 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0001 | 0.0015 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Wolbachia endosymbiont of Brugia malayi | cell division protein FtsI | 0.0172 | 0.0324 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0376 | 0.0753 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.002 | 0.0002 | 1 |
Echinococcus multilocularis | cysteine protease | 0.002 | 0.0002 | 0.0026 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0376 | 0.0753 | 0.0753 |
Brugia malayi | beta-lactamase family protein | 0.0376 | 0.0753 | 1 |
Mycobacterium leprae | POSSIBLE PENICILLIN-BINDING LIPOPROTEIN | 0.0172 | 0.0324 | 0.0677 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Onchocerca volvulus | 0.002 | 0.0002 | 0.0026 | |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0376 | 0.0753 | 0.0753 |
Loa Loa (eye worm) | hypothetical protein | 0.0376 | 0.0753 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0001 | 0.0015 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0172 | 0.0324 | 0.4297 |
Mycobacterium leprae | Probable penicillin-binding protein PbpA | 0.0172 | 0.0324 | 0.0677 |
Mycobacterium ulcerans | bifunctional penicillin-binding protein 1A/1B PonA1 | 0.0172 | 0.0324 | 0.0324 |
Mycobacterium tuberculosis | Probable bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 (murein polymerase) [includes: penicillin-insen | 0.0172 | 0.0324 | 0.0324 |
Onchocerca volvulus | Cathepsin L homolog | 0.002 | 0.0002 | 0.0026 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0001 | 0.0015 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.002 | 0.0002 | 0.0026 |
Mycobacterium leprae | PROBABLE CONSERVED LIPOPROTEIN LPQF | 0.228 | 0.4779 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.002 | 0.0002 | 0.0435 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0001 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0001 | 0.0015 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0001 | 0.0015 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0001 | 0.0015 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0001 | 0.0015 |
Leishmania major | cathepsin L-like protease | 0.002 | 0.0002 | 0.0026 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0002 | 0.0026 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0001 | 0.0015 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Giardia lamblia | Metallo-beta-lactamase superfamily protein | 0.0019 | 0 | 0.5 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0376 | 0.0753 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0001 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0153 | 0.2029 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0077 | 0.0122 | 0.162 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0001 | 0.0015 |
Plasmodium vivax | hypothetical protein, conserved | 0.0376 | 0.0753 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0376 | 0.0753 | 1 |
Mycobacterium ulcerans | lipoprotein LpqF | 0.228 | 0.4779 | 0.4779 |
Mycobacterium tuberculosis | Conserved protein | 0.0376 | 0.0753 | 0.0753 |
Loa Loa (eye worm) | ctsf protein | 0.002 | 0.0002 | 0.0026 |
Mycobacterium tuberculosis | Conserved protein | 0.0376 | 0.0753 | 0.0753 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0376 | 0.0753 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0376 | 0.0753 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein LpqF | 0.228 | 0.4779 | 0.4779 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.0122 | 0.0255 |
Onchocerca volvulus | 0.002 | 0.0001 | 0.0015 | |
Loa Loa (eye worm) | hypothetical protein | 0.0376 | 0.0753 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.002 | 0.0001 | 0.0015 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0001 | 0.0015 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.007 | 0.0108 | 0.1433 |
Mycobacterium ulcerans | lipase LipD | 0.0376 | 0.0753 | 0.0753 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0001 | 0.0015 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0001 | 0.0015 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.24 | 0.5032 | 0.5032 |
Onchocerca volvulus | 0.0376 | 0.0753 | 1 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.002 | 0.0002 | 0.0435 |
Chlamydia trachomatis | transglycolase/transpeptidase | 0.0172 | 0.0324 | 1 |
Trypanosoma brucei | beta lactamase | 0.228 | 0.4779 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0077 | 0.0121 | 0.1607 |
Leishmania major | cathepsin L-like protease | 0.0077 | 0.0122 | 0.162 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.002 | 0.0002 | 0.0026 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.0122 | 0.0255 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0001 | 0.0015 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0001 | 0.0015 |
Echinococcus multilocularis | cysteine protease | 0.002 | 0.0002 | 0.0026 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0094 | 0.0158 | 0.2102 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0001 | 0.0015 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0001 | 0.0015 |
Giardia lamblia | Hydroxyacylglutathione hydrolase | 0.0019 | 0 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.0001 | 0.0015 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0001 | 0.0015 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0376 | 0.0753 | 0.0753 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0077 | 0.0122 | 0.162 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0001 | 0.0015 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0376 | 0.0753 | 1 |
Brugia malayi | bZIP transcription factor family protein | 0.0094 | 0.0158 | 0.2102 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.002 | 0.0002 | 0.0026 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0001 | 0.0015 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.0045 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Leishmania major | cathepsin L-like protease | 0.002 | 0.0002 | 0.0026 |
Leishmania major | cathepsin L-like protease | 0.0077 | 0.0122 | 0.162 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Leishmania major | cathepsin L-like protease | 0.0077 | 0.0122 | 0.162 |
Treponema pallidum | penicillin-binding protein (pbp-3) | 0.0172 | 0.0324 | 1 |
Trichomonas vaginalis | esterase, putative | 0.0376 | 0.0753 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0001 | 0.0015 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0001 | 0.0015 |
Loa Loa (eye worm) | hypothetical protein | 0.0376 | 0.0753 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.004 | 0.0045 | 0.0591 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0001 | 0.0015 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0376 | 0.0753 | 0.0753 |
Toxoplasma gondii | cathepsin CPL | 0.002 | 0.0002 | 0.0026 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.002 | 0.0002 | 1 |
Onchocerca volvulus | 0.0376 | 0.0753 | 1 | |
Brugia malayi | beta-lactamase family protein | 0.0376 | 0.0753 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0001 | 0.0015 |
Schistosoma mansoni | jun-related protein | 0.0077 | 0.0121 | 0.1607 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0045 | 0.0591 |
Onchocerca volvulus | 0.002 | 0.0002 | 0.0026 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0077 | 0.0122 | 0.162 |
Mycobacterium tuberculosis | Conserved protein | 0.0376 | 0.0753 | 0.0753 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0001 | 0.0015 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0001 | 0.0015 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.002 | 0.0002 | 0.0026 |
Chlamydia trachomatis | transglycolase/transpeptidase | 0.0172 | 0.0324 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0001 | 0.0015 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0376 | 0.0753 | 0.0753 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0077 | 0.0122 | 0.0255 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0001 | 0.0015 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0376 | 0.0753 | 1 |
Onchocerca volvulus | 0.002 | 0.0002 | 0.0026 | |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0001 | 0.0015 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.