Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0047 | 0.0097 | 0.0089 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.0018 | 0.0009 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0013 | 0.0007 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0013 | 0.0004 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0013 | 0.0007 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0158 | 0.0484 | 0.0476 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0013 | 0.0007 |
Schistosoma mansoni | lamin | 0.0169 | 0.0523 | 0.0515 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0055 | 0.0074 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0047 | 0.0097 | 0.0089 |
Schistosoma mansoni | hypothetical protein | 0.1294 | 0.4474 | 0.4469 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0206 | 0.0197 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0097 | 0.0143 |
Echinococcus granulosus | carbonic anhydrase | 0.1294 | 0.4474 | 0.4469 |
Leishmania major | hypothetical protein, conserved | 0.0048 | 0.0098 | 0.0089 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.004 | 0.0031 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0098 | 0.0275 | 0.0266 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0013 | 0.0004 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0048 | 0.0098 | 0.0089 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0013 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0216 | 0.0208 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0029 | 0.0034 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0025 | 0.0018 | 0.0009 |
Onchocerca volvulus | 0.0169 | 0.0523 | 0.6681 | |
Mycobacterium tuberculosis | Beta-carbonic anhydrase CanB | 0.1068 | 0.368 | 0.9297 |
Brugia malayi | MH2 domain containing protein | 0.0363 | 0.1204 | 0.1196 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.1294 | 0.4474 | 0.4469 |
Schistosoma mansoni | lamin | 0.0169 | 0.0523 | 0.0515 |
Entamoeba histolytica | carbonic anhydrase, putative | 0.1707 | 0.5924 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0063 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0013 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.004 | 0.0031 |
Mycobacterium tuberculosis | Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) | 0.0918 | 0.3152 | 0.7959 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0013 | 0.0007 |
Onchocerca volvulus | 0.0169 | 0.0523 | 0.6681 | |
Schistosoma mansoni | intermediate filament proteins | 0.0169 | 0.0523 | 0.0515 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0013 | 0.001 |
Schistosoma mansoni | carbonic anhydrase-related | 0.1294 | 0.4474 | 0.4469 |
Loa Loa (eye worm) | hypothetical protein | 0.1294 | 0.4474 | 0.4469 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase | 0.1147 | 0.3958 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0063 | 0.0088 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.1294 | 0.4474 | 0.4469 |
Brugia malayi | MH1 domain containing protein | 0.0025 | 0.0018 | 0.0009 |
Mycobacterium ulcerans | hypothetical protein | 0.0175 | 0.0547 | 0.0869 |
Echinococcus multilocularis | carbonic anhydrase II | 0.2868 | 1 | 1 |
Plasmodium vivax | sulfate transporter, putative | 0.0038 | 0.0065 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0063 | 0.0088 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0039 | 0.0049 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0041 | 0.0073 | 0.0104 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0047 | 0.0097 | 0.015 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0047 | 0.0097 | 0.0089 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.2868 | 1 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0013 | 0.0007 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0025 | 0.0018 | 0.0009 |
Echinococcus granulosus | lamin dm0 | 0.0169 | 0.0523 | 0.0515 |
Echinococcus granulosus | lamin | 0.0169 | 0.0523 | 0.0515 |
Onchocerca volvulus | Putative sulfate transporter | 0.0241 | 0.0776 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0097 | 0.0143 |
Echinococcus multilocularis | musashi | 0.0169 | 0.0523 | 0.0515 |
Mycobacterium tuberculosis | Probable serine acetyltransferase CysE (sat) | 0.0083 | 0.0222 | 0.054 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0013 | 0.0007 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0021 | 0.0019 |
Echinococcus multilocularis | Smad4 | 0.0025 | 0.0018 | 0.0009 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0055 | 0.0074 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0035 | 0.0055 | 0.0103 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0333 | 0.11 | 0.1092 |
Brugia malayi | Smad1 | 0.0025 | 0.0018 | 0.0009 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0021 | 0.0019 |
Echinococcus granulosus | carbonic anhydrase | 0.1294 | 0.4474 | 0.4469 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0047 | 0.0095 | 0.0087 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.004 | 0.0031 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0047 | 0.0097 | 0.0097 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0013 | 0.0004 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.003 | 0.0035 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0025 | 0.0018 | 0.0009 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.0018 | 0.0009 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0047 | 0.0097 | 0.0089 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0363 | 0.1204 | 0.1196 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0158 | 0.0484 | 0.0484 |
Mycobacterium ulcerans | carbonic anhydrase | 0.1707 | 0.5924 | 0.9552 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0063 | 0.0088 |
Entamoeba histolytica | acetyltransferase, putative | 0.0083 | 0.0222 | 0.036 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0022 | 0.0009 | 0.5 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0032 | 0.0043 | 0.0055 |
Schistosoma mansoni | carbonic anhydrase | 0.1707 | 0.5924 | 0.5921 |
Echinococcus granulosus | smad | 0.0025 | 0.0018 | 0.0009 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0047 | 0.0097 | 0.0089 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.1294 | 0.4474 | 0.4469 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.2868 | 1 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0013 | 0.0007 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0021 | 0.002 |
Echinococcus multilocularis | lamin | 0.0169 | 0.0523 | 0.0515 |
Onchocerca volvulus | 0.008 | 0.0211 | 0.2594 | |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0013 | 0.0004 |
Echinococcus multilocularis | carbonic anhydrase | 0.1294 | 0.4474 | 0.4469 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.2868 | 1 | 1 |
Echinococcus granulosus | tumor protein p63 | 0.1026 | 0.3534 | 0.3528 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.009 | 0.0248 | 0.024 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.1294 | 0.4474 | 0.4469 |
Entamoeba histolytica | ankyrin, putative | 0.0083 | 0.0222 | 0.036 |
Plasmodium falciparum | carbonic anhydrase | 0.1294 | 0.4474 | 1 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.2868 | 1 | 1 |
Echinococcus multilocularis | tumor protein p63 | 0.1026 | 0.3534 | 0.3528 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0055 | 0.0074 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0175 | 0.0547 | 0.1363 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0098 | 0.0275 | 0.0266 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.004 | 0.0031 |
Schistosoma mansoni | carbonic anhydrase-related | 0.1294 | 0.4474 | 0.4469 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0025 | 0.0018 | 0.0009 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0038 | 0.0063 | 0.0063 |
Mycobacterium tuberculosis | Possible siderophore-binding protein | 0.0048 | 0.0098 | 0.0226 |
Leishmania major | carbonic anhydrase-like protein | 0.2868 | 1 | 1 |
Echinococcus granulosus | carbonic anhydrase II | 0.2868 | 1 | 1 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.2868 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.004 | 0.0031 |
Echinococcus multilocularis | lamin dm0 | 0.0169 | 0.0523 | 0.0515 |
Loa Loa (eye worm) | Smad1 | 0.0025 | 0.0018 | 0.0009 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0055 | 0.0074 |
Mycobacterium leprae | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) | 0.1707 | 0.5924 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0013 | 0.0007 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0047 | 0.0097 | 0.0097 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0047 | 0.0095 | 0.0095 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.2868 | 1 | 1 |
Mycobacterium leprae | PROBABLE TRANSFERASE | 0.008 | 0.0211 | 0.0335 |
Loa Loa (eye worm) | hypothetical protein | 0.1294 | 0.4474 | 0.4469 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0081 | 0.0216 | 0.0208 |
Mycobacterium ulcerans | carbonic anhydrase | 0.1786 | 0.6202 | 1 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0047 | 0.0097 | 0.0089 |
Mycobacterium ulcerans | transferase | 0.008 | 0.0211 | 0.0326 |
Wolbachia endosymbiont of Brugia malayi | carbonic anhydrase | 0.0048 | 0.0098 | 0.418 |
Schistosoma mansoni | carbonic anhydrase-related | 0.1294 | 0.4474 | 0.4469 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0025 | 0.0018 | 0.0009 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0169 | 0.0523 | 0.0515 |
Onchocerca volvulus | 0.015 | 0.0458 | 0.5834 | |
Brugia malayi | MH2 domain containing protein | 0.0025 | 0.0018 | 0.0009 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.004 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.2689 | 0.937 | 0.937 |
Wolbachia endosymbiont of Brugia malayi | 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase | 0.0083 | 0.0222 | 1 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.009 | 0.0248 | 0.024 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.004 | 0.0031 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0022 | 0.001 | 0.001 |
Toxoplasma gondii | inorganic anion transporter, sulfate permease (SulP) family protein | 0.0038 | 0.0065 | 0.0127 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0048 | 0.0098 | 0.0089 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0021 | 0.002 |
Schistosoma mansoni | Smad4 | 0.0025 | 0.0018 | 0.0009 |
Mycobacterium ulcerans | integral membrane transporter | 0.0038 | 0.0065 | 0.0092 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.004 | 0.0031 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0029 | 0.0034 |
Echinococcus granulosus | Smad4 | 0.0025 | 0.0018 | 0.0009 |
Onchocerca volvulus | 0.0241 | 0.0776 | 1 | |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0169 | 0.0523 | 0.0515 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0067 | 0.0166 | 0.0157 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.2868 | 1 | 1 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0047 | 0.0097 | 0.0089 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0063 | 0.0088 |
Giardia lamblia | GTOR | 0.0047 | 0.0097 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0048 | 0.0098 | 0.0144 |
Brugia malayi | MH1 domain containing protein | 0.0025 | 0.0018 | 0.0009 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.003 | 0.0035 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0333 | 0.11 | 0.1092 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0098 | 0.0275 | 0.0266 |
Echinococcus multilocularis | smad | 0.0025 | 0.0018 | 0.0009 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0158 | 0.0484 | 0.0476 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.1294 | 0.4474 | 0.4469 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0038 | 0.0063 | 0.0055 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0055 | 0.0074 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0038 | 0.0063 | 0.0055 |
Trypanosoma brucei | Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative | 0.0038 | 0.0065 | 0.0065 |
Toxoplasma gondii | hypothetical protein | 0.0054 | 0.0119 | 0.0248 |
Toxoplasma gondii | hypothetical protein | 0.1294 | 0.4474 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0097 | 0.0143 |
Entamoeba histolytica | bacterial transferase hexapeptide family protein | 0.0048 | 0.0098 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0275 | 0.0266 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.004 | 0.0031 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0081 | 0.0216 | 0.0208 |
Echinococcus multilocularis | carbonic anhydrase | 0.1294 | 0.4474 | 0.4469 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0013 | 0.0007 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0021 | 0.002 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.004 | 0.0031 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1786 | 0.6202 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0047 | 0.0095 | 0.0087 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0013 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0013 | 0.0004 |
Plasmodium falciparum | inorganic anion exchanger, inorganic anion antiporter | 0.0038 | 0.0065 | 0.0127 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.004 | 0.0031 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0333 | 0.11 | 0.1092 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.0013 | 0.0007 |
Trichomonas vaginalis | maltose O-acetyltransferase, putative | 0.008 | 0.0211 | 0.0326 |
Brugia malayi | MH2 domain containing protein | 0.0025 | 0.0018 | 0.0009 |
Leishmania major | carbonic anhydrase family protein, putative | 0.1707 | 0.5924 | 0.5921 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.2868 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.008 | 0.0211 | 0.0326 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0025 | 0.0018 | 0.0009 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0363 | 0.1204 | 0.1196 |
Schistosoma mansoni | smad1 5 8 and | 0.0025 | 0.0018 | 0.0009 |
Mycobacterium leprae | Probable transmembrane transport protein | 0.0278 | 0.0907 | 0.1513 |
Brugia malayi | intermediate filament protein | 0.0169 | 0.0523 | 0.0515 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.0009 | 0.0009 |
Schistosoma mansoni | smad | 0.0025 | 0.0018 | 0.0009 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.015 | 0.0458 | 0.045 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0013 | 0.001 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0013 | 0.0007 |
Schistosoma mansoni | carbonic anhydrase | 0.1294 | 0.4474 | 0.4469 |
Mycobacterium ulcerans | transmembrane carbonic anhydrase, SulP | 0.0038 | 0.0065 | 0.0092 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0166 | 0.0157 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0047 | 0.0097 | 0.0089 |
Chlamydia trachomatis | sulfate transporter | 0.0038 | 0.0065 | 0.5 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0021 | 0.002 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.0523 | 0.0515 |
Echinococcus multilocularis | carbonic anhydrase | 0.1294 | 0.4474 | 0.4469 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0206 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.0458 | 0.045 |
Mycobacterium ulcerans | transmembrane carbonic anhydrase, SulP | 0.0038 | 0.0065 | 0.0092 |
Wolbachia endosymbiont of Brugia malayi | N-acetylglucosamine-1-phosphate uridyltransferase | 0.0083 | 0.0222 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0055 | 0.0074 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0055 | 0.0074 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.004 | 0.0031 |
Echinococcus granulosus | carbonic anhydrase | 0.1294 | 0.4474 | 0.4469 |
Echinococcus granulosus | dynactin 5 p25 | 0.0083 | 0.0222 | 0.0213 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0013 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0166 | 0.0157 |
Trypanosoma cruzi | Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative | 0.0038 | 0.0065 | 0.0057 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.003 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.0512 | 0.0504 |
Echinococcus granulosus | intermediate filament protein | 0.0169 | 0.0523 | 0.0515 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0047 | 0.0097 | 0.0089 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0047 | 0.0095 | 0.0087 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.004 | 0.0031 |
Loa Loa (eye worm) | intermediate filament protein | 0.0169 | 0.0523 | 0.0515 |
Trypanosoma cruzi | Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative | 0.0038 | 0.0065 | 0.0057 |
Mycobacterium tuberculosis | Probable conserved transmembrane protein | 0.0278 | 0.0907 | 0.2276 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0057 | 0.0131 | 0.0123 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0021 | 0.0019 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.004 | 0.0031 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.1294 | 0.4474 | 0.4469 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0025 | 0.0018 | 0.0009 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1786 | 0.6202 | 1 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0047 | 0.0097 | 0.015 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0333 | 0.11 | 0.11 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0048 | 0.0098 | 0.0098 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
LD50 (functional) | = 4525 mg kg-1 | LD50 following oral dosing. | ChEMBL. | 15239660 |
Survival (functional) | = 50 % | Percent survival against percutaneously administered sulfur mustard in mice (38.7 mg/kg) after 14 days. | ChEMBL. | 15239660 |
Survival (functional) | = 100 % | Percent survival against percutaneously administered sulfur mustard in mice (38.7 mg/kg) after 7 days. | ChEMBL. | 15239660 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.