Detailed information for compound 217108

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 250.165 | Formula: C11H17Cl2NO
  • H donors: 1 H acceptors: 1 LogP: 3.65 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(CCCc1ccc(c(c1)Cl)O)C.Cl
  • InChi: 1S/C11H16ClNO.ClH/c1-13(2)7-3-4-9-5-6-11(14)10(12)8-9;/h5-6,8,14H,3-4,7H2,1-2H3;1H
  • InChiKey: BZHTUCZRDUWRFI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni multidrug resistance protein 0.0504 1 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0349 0.6643 1
Brugia malayi ABC transporter family protein 0.0177 0.2919 0.2919
Brugia malayi P-glycoprotein-like protein 0.0177 0.2919 0.2919
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0349 0.6643 1
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0504 1 1
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0349 0.6643 0.6609
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0349 0.6643 1
Trichomonas vaginalis ABC transporter, putative 0.0349 0.6643 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0349 0.6643 1
Echinococcus multilocularis multidrug resistance protein 1 0.0349 0.6643 0.6609
Plasmodium vivax ABC transporter B family member 3, putative 0.0177 0.2919 0.4309
Trypanosoma cruzi cytochrome P450, putative 0.0163 0.2612 0.254
Loa Loa (eye worm) CYP4Cod1 0.0163 0.2612 0.254
Entamoeba histolytica ATP-binding cassette protein, putative 0.0504 1 1
Brugia malayi Cytochrome P450 family protein 0.0163 0.2612 0.2612
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0047 0.0099 0.0099
Brugia malayi TAR-binding protein 0.0073 0.0671 0.0671
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0349 0.6643 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0349 0.6643 1
Loa Loa (eye worm) hypothetical protein 0.0116 0.1597 0.1514
Schistosoma mansoni multidrug resistance protein 0.0504 1 1
Entamoeba histolytica ABC transporter, putative 0.0504 1 1
Schistosoma mansoni smdr2 0.0349 0.6643 0.6609
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0047 0.0099 0.0099
Brugia malayi ABC transporter transmembrane region family protein 0.0177 0.2919 0.2919
Leishmania major ATP-binding cassette protein subfamily B, member 3, putative 0.0177 0.2919 0.2849
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0671 0.0579
Entamoeba histolytica multidrug resistance protein, putative 0.0504 1 1
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0349 0.6643 0.6609
Plasmodium falciparum ABC transporter B family member 3, putative 0.0177 0.2919 0.4309
Entamoeba histolytica P-glycoprotein-2, putative 0.0349 0.6643 0.5347
Echinococcus granulosus multidrug resistance associated protein 1 0.0504 1 1
Echinococcus multilocularis ATP binding cassette sub family B 0.0177 0.2919 0.2849
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0349 0.6643 0.6609
Echinococcus granulosus ATP binding cassette sub family B 0.0177 0.2919 0.2849
Echinococcus granulosus multidrug resistance protein 1 0.0349 0.6643 0.6609
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.0047 0.0099 0.0099
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0671 0.0579
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0349 0.6643 1
Brugia malayi ABC transporter family protein 0.0177 0.2919 0.2919
Trichomonas vaginalis abcb9, putative 0.0349 0.6643 1
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0177 0.2919 0.2849
Loa Loa (eye worm) hypothetical protein 0.0171 0.2785 0.2714
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0349 0.6643 1
Echinococcus granulosus multidrug resistance protein 1 0.0178 0.294 0.287
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0073 0.0671 0.0579
Echinococcus multilocularis ATP binding cassette sub family B 0.0343 0.6509 0.6474
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0177 0.2919 0.0347
Trichomonas vaginalis ABC transporter, putative 0.0349 0.6643 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0349 0.6643 1
Brugia malayi multidrug resistance protein 3 0.0349 0.6643 0.6643
Schistosoma mansoni hypothetical protein 0.0196 0.3332 0.3266
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0163 0.2612 0.8914
Schistosoma mansoni multidrug resistance protein 0.0504 1 1
Loa Loa (eye worm) multidrug resistance-associated protein 0.0333 0.6297 0.6261
Brugia malayi ABC transporter family protein 0.0349 0.6643 0.6643
Schistosoma mansoni smdr1 0.0177 0.2919 0.2849
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0177 0.2919 0.2919
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0671 0.0579
Loa Loa (eye worm) ABC transporter 0.0177 0.2919 0.2849
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0177 0.2919 0.2849
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0504 1 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0349 0.6643 0.6609
Brugia malayi ABC transporter family protein 0.0177 0.2919 0.2919
Entamoeba histolytica P-glycoprotein 6, putative 0.0177 0.2919 0.0185
Loa Loa (eye worm) RNA binding protein 0.0073 0.0671 0.0579
Trichomonas vaginalis abcb9, putative 0.0349 0.6643 1
Schistosoma mansoni hypothetical protein 0.0047 0.0099 0.0001
Onchocerca volvulus 0.0349 0.6643 0.5
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0177 0.2919 1
Loa Loa (eye worm) hypothetical protein 0.0504 1 1
Brugia malayi RNA recognition motif domain containing protein 0.0073 0.0671 0.0671
Leishmania major ATP-binding cassette protein subfamily B, member 1, putative 0.0177 0.2919 0.2849
Entamoeba histolytica P-glycoprotein 5, putative 0.0349 0.6643 0.5347
Giardia lamblia ABC transporter, putative 0.0504 1 1
Trypanosoma brucei ABC transporter, mitochondrial, putative 0.0177 0.2919 0.2849
Echinococcus granulosus multidrug resistance protein 1 0.0178 0.294 0.287
Plasmodium falciparum ABC transporter B family member 6, putative 0.0177 0.2919 0.4309
Entamoeba histolytica P-glycoprotein 6, putative 0.0177 0.2919 0.0185
Schistosoma mansoni hypothetical protein 0.0196 0.3332 0.3266
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0349 0.6643 0.6609
Echinococcus multilocularis multidrug resistance protein 1 0.0178 0.294 0.287
Plasmodium vivax ABC transporter B family member 6, putative 0.0177 0.2919 0.4309
Entamoeba histolytica hypothetical protein 0.0504 1 1
Echinococcus granulosus ATP binding cassette sub family B 0.0177 0.2919 0.2849
Brugia malayi cytochrome P450 0.0047 0.0098 0.0098
Entamoeba histolytica P-glycoprotein-2 0.0349 0.6643 0.5347
Loa Loa (eye worm) hypothetical protein 0.0497 0.9866 0.9865
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0349 0.6643 1
Leishmania major cytochrome p450-like protein 0.0163 0.2612 0.254
Loa Loa (eye worm) cytochrome P450 family protein 0.0163 0.2612 0.254
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0349 0.6643 0.6609
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0504 1 1
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0177 0.2919 1
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0349 0.6643 0.6609
Loa Loa (eye worm) ABC transporter 0.0177 0.2919 0.2849
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM10, putative 0.0055 0.0279 0.0276
Echinococcus granulosus expressed protein 0.0055 0.0279 0.0184
Plasmodium vivax ABC transporter B family member 5, putative 0.0177 0.2919 0.4309
Leishmania major ATP-binding cassette protein subfamily C, member 8, putative 0.0177 0.2919 0.2849
Brugia malayi Cytochrome P450 family protein 0.0047 0.0098 0.0098
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0177 0.2919 1
Echinococcus multilocularis multidrug resistance associated protein 7 0.0504 1 1
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0177 0.2919 0.2849
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0177 0.2919 0.2849
Schistosoma mansoni multidrug resistance protein 0.0349 0.6643 0.6609
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0504 1 1
Echinococcus granulosus ATP binding cassette sub family B 0.0171 0.2785 0.2714
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0349 0.6643 0.6609
Giardia lamblia Multidrug resistance-associated protein 1 0.0504 1 1
Toxoplasma gondii TIM10 family protein, putative 0.0055 0.0279 0.0184
Echinococcus multilocularis geminin 0.0196 0.3332 0.3266
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0177 0.2919 0.2849
Loa Loa (eye worm) transport to inner mitochondrial membrane family member 0.0055 0.0279 0.0184
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0349 0.6643 0.6609
Plasmodium vivax multidrug resistance protein 2, putative 0.0177 0.2919 0.4309
Entamoeba histolytica P-glycoprotein-5 0.0349 0.6643 0.5347
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM10, putative 0.0055 0.0279 0.0276
Echinococcus multilocularis multidrug resistance associated protein 4 0.0327 0.6163 0.6126
Echinococcus multilocularis ATP binding cassette sub family B 0.0177 0.2919 0.2849
Echinococcus granulosus tar DNA binding protein 0.0073 0.0671 0.0579
Entamoeba histolytica P-glycoprotein-2 0.0349 0.6643 0.5347
Plasmodium falciparum ABC transporter B family member 5, putative 0.0177 0.2919 0.4309
Trypanosoma brucei p-glycoprotein 0.0504 1 1
Echinococcus granulosus multidrug resistance associated protein 4 0.0327 0.6163 0.6126
Brugia malayi multidrug resistance related protein 1 0.0504 1 1
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0349 0.6643 1
Brugia malayi ABC transporter transmembrane region family protein 0.0171 0.2785 0.2785
Loa Loa (eye worm) hypothetical protein 0.0349 0.6643 0.6609
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0349 0.6643 0.6609
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0671 0.0579
Leishmania major pentamidine resistance protein 1 0.0504 1 1
Trichomonas vaginalis taga, putative 0.0349 0.6643 1
Trypanosoma brucei cytochrome P450, putative 0.0163 0.2612 0.254
Brugia malayi Mitochondrial import inner membrane translocase subunit TIM10 0.0055 0.0279 0.0279
Brugia malayi ABC transporter 0.0171 0.2785 0.2785
Wolbachia endosymbiont of Brugia malayi ABC-type protease secretion system, ATPase and permease component, AprD 0.0177 0.2919 0.5
Trichomonas vaginalis ABC transporter, putative 0.0349 0.6643 1
Echinococcus multilocularis 0.0177 0.2919 0.2849
Plasmodium falciparum multidrug resistance protein 1 0.0349 0.6643 1
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0171 0.2785 0.2714
Entamoeba histolytica P-glycoprotein-1 0.0349 0.6643 0.5347
Trypanosoma cruzi hypothetical protein 0.0327 0.6163 0.6126
Loa Loa (eye worm) multidrug resistance protein 3 0.0349 0.6643 0.6609
Loa Loa (eye worm) hypothetical protein 0.0349 0.6643 0.6609
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0504 1 1
Leishmania major ABC-thiol transporter 0.0504 1 1
Mycobacterium tuberculosis Probable drugs-transport transmembrane ATP-binding protein ABC transporter 0.0177 0.2919 0.431
Trichomonas vaginalis abcb9, putative 0.0349 0.6643 1
Brugia malayi Cytochrome P450 family protein 0.0163 0.2612 0.2612
Echinococcus granulosus multidrug resistance protein 1 0.0349 0.6643 0.6609
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0177 0.2919 0.2849
Entamoeba histolytica ATP-binding cassette protein, putative 0.0504 1 1
Brugia malayi Cytochrome P450 family protein 0.0047 0.0098 0.0098
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0349 0.6643 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0163 0.2612 0.254
Plasmodium vivax multidrug resistance-associated protein 2, putative 0.0177 0.2919 0.4309
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.0047 0.0099 0.0001
Mycobacterium ulcerans drugs-transport transmembrane ATP-binding protein ABC transporter 0.0177 0.2919 1
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0671 0.0579
Entamoeba histolytica ATP-binding cassette protein, putative 0.0504 1 1
Echinococcus multilocularis multidrug resistance associated protein 1 0.0504 1 1
Echinococcus multilocularis ATP binding cassette sub family B 0.0177 0.2919 0.2849
Echinococcus granulosus geminin 0.0196 0.3332 0.3266
Loa Loa (eye worm) hypothetical protein 0.0177 0.2919 0.2849
Toxoplasma gondii mitochondrial import inner membrane translocase subunit TIM10, putative 0.0055 0.0279 0.0184
Toxoplasma gondii ATP-binding cassette sub-family B member 5 0.0177 0.2919 0.2849
Leishmania major p-glycoprotein 0.0349 0.6643 0.6609
Echinococcus granulosus multidrug resistance associated protein 7 0.0504 1 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0349 0.6643 1
Plasmodium falciparum multidrug resistance protein 2 0.0177 0.2919 0.4309
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0178 0.294 0.0401
Loa Loa (eye worm) ABC transporter 0.0177 0.2919 0.2849
Schistosoma mansoni multidrug resistance protein 0.0349 0.6643 0.6609
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0349 0.6643 0.6609
Toxoplasma gondii ABC transporter family protein 0.0177 0.2919 0.2849
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0504 1 1
Loa Loa (eye worm) hypothetical protein 0.0343 0.6509 0.6474
Mycobacterium ulcerans component linked with the assembly of cytochrome transport transmembrane ATP-binding protein ABC transporter CydD 0.0177 0.2919 1
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0349 0.6643 1
Plasmodium vivax ABC transporter B family member 7, putative 0.0177 0.2919 0.4309
Echinococcus multilocularis tar DNA binding protein 0.0073 0.0671 0.0579
Loa Loa (eye worm) hypothetical protein 0.0047 0.0099 0.0001
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0504 1 1
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0504 1 1
Schistosoma mansoni multidrug resistance protein 0.0171 0.2785 0.2714
Schistosoma mansoni multidrug resistance protein 0.0349 0.6643 0.6609
Giardia lamblia Multidrug resistance-associated protein 1 0.0504 1 1
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0349 0.6643 0.6609
Loa Loa (eye worm) TAR-binding protein 0.0073 0.0671 0.0579
Schistosoma mansoni multidrug resistance protein 0.0177 0.2919 0.2849
Entamoeba histolytica ATP-binding cassette protein, putative 0.0504 1 1
Plasmodium falciparum multidrug resistance-associated protein 2 0.0177 0.2919 0.4309
Echinococcus multilocularis ATP binding cassette sub family B 0.0177 0.2919 0.2849
Trypanosoma cruzi cytochrome P450, putative 0.0163 0.2612 0.254
Trypanosoma brucei multidrug resistance protein E 0.0504 1 1
Entamoeba histolytica P-glyco protein 6, putative 0.0349 0.6643 0.5347
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0349 0.6643 1
Giardia lamblia Multidrug resistance-associated protein 1 0.0497 0.9866 0.9815
Loa Loa (eye worm) hypothetical protein 0.0504 1 1
Mycobacterium tuberculosis Iron-regulated transporter IrtA 0.0177 0.2919 0.431
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.0047 0.0099 0.0001
Leishmania major p-glycoprotein e 0.0504 1 1
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0504 1 1
Plasmodium vivax multidrug resistance protein 1, putative 0.0349 0.6643 1
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0177 0.2919 1
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0504 1 1
Trichomonas vaginalis ABC transporter, putative 0.0349 0.6643 1
Schistosoma mansoni mitochondrial import inner membrane translocase subunit tim10 0.0055 0.0279 0.0184
Echinococcus granulosus multidrug resistance protein 1 0.0349 0.6643 0.6609
Brugia malayi ABC transporter 0.0177 0.2919 0.2919
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0349 0.6643 1
Plasmodium falciparum ABC transporter B family member 7, putative 0.0177 0.2919 0.4309
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0349 0.6643 1
Giardia lamblia MRP-like ABC transporter 0.0504 1 1
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0177 0.2919 0.2849
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0177 0.2919 0.2849
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0343 0.6509 0.6474
Trypanosoma brucei ABC transporter of the mitochondrion, putative 0.0177 0.2919 0.2849
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0349 0.6643 1
Echinococcus multilocularis expressed protein 0.0055 0.0279 0.0184
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0177 0.2919 1
Plasmodium falciparum multidrug resistance-associated protein 1 0.0177 0.2919 0.4309
Brugia malayi hypothetical protein 0.0177 0.2919 0.2919
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0349 0.6643 1
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.0177 0.2919 0.4309
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0349 0.6643 1
Plasmodium falciparum ABC transporter B family member 4, putative 0.0177 0.2919 0.4309
Toxoplasma gondii ABC transporter, putative 0.0177 0.2919 0.2849
Brugia malayi RNA binding protein 0.0073 0.0671 0.0671
Echinococcus multilocularis multidrug resistance protein 1 0.0349 0.6643 0.6609
Trypanosoma cruzi multidrug resistance protein E, putative 0.0504 1 1
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0349 0.6643 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0349 0.6643 0.6609
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0349 0.6643 0.5
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0349 0.6643 1
Schistosoma mansoni multidrug resistance protein 0.0504 1 1
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0349 0.6643 1
Wolbachia endosymbiont of Brugia malayi ABC-type multidrug transport system, ATPase and permease component 0.0177 0.2919 0.5
Plasmodium vivax ABC transporter B family member 4, putative 0.0177 0.2919 0.4309

Activities

Activity type Activity value Assay description Source Reference
Log AC50 (functional) = 3.82 uM Elevation of the threshold alternating current to induce arrhythmia in isolated guinea pig heart. ChEMBL. 10508436
Log IC50 (functional) 0 uM Concentration at which Ca+ binding to phosphatidylserine monolayers is reduced to 50% of control; X = Not measured ChEMBL. 10508436
logP (ADMET) = 0.97 Partition coefficient (logP) (HPLC) ChEMBL. 10508436
pKa (ADMET) 0 Partion coefficient of the compound measured by aqueous titration of hydrochlorides; X = Not measured ChEMBL. 10508436
Tt (functional) = 294 k Drug induced phase transition temperature with DPPA liposome. ChEMBL. 10508436

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.