Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | hypoxanthine-guanine phosphoribosyltransferase, putative | 0.0189 | 0.3924 | 1 |
Onchocerca volvulus | 0.0189 | 0.3924 | 0.3801 | |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0478 | 0.1219 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0074 | 0.1307 | 0.205 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0025 | 0.0199 | 0.0199 |
Onchocerca volvulus | 0.0033 | 0.0385 | 0.0189 | |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0025 | 0.0199 | 0.0199 |
Echinococcus multilocularis | transcription factor btf3 | 0.0036 | 0.0454 | 0.0686 |
Plasmodium vivax | unspecified product | 0.0033 | 0.0385 | 0.0239 |
Mycobacterium tuberculosis | Probable orotate phosphoribosyltransferase PyrE (OPRT) (oprtase) | 0.0044 | 0.064 | 0.1009 |
Schistosoma mansoni | lozenge | 0.0057 | 0.0936 | 0.1979 |
Loa Loa (eye worm) | orotate phosphoribosyltransferase | 0.0044 | 0.064 | 0.064 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0298 | 0.0101 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0036 | 0.0454 | 0.0432 |
Echinococcus granulosus | hypoxanthine guanine phosphoribosyltransferase | 0.0189 | 0.3924 | 1 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0025 | 0.0199 | 0.0507 |
Plasmodium falciparum | orotate phosphoribosyltransferase | 0.0044 | 0.064 | 0.0723 |
Echinococcus granulosus | sex peptide receptor | 0.0025 | 0.0199 | 0.0507 |
Schistosoma mansoni | transcription factor btf3 | 0.0036 | 0.0454 | 0.0686 |
Echinococcus granulosus | serotonin receptor | 0.0025 | 0.0199 | 0.0507 |
Brugia malayi | beta-NAC-like protein | 0.0036 | 0.0454 | 0.0261 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0385 | 0.0498 |
Mycobacterium leprae | POSSIBLE PENICILLIN-BINDING LIPOPROTEIN | 0.0074 | 0.1307 | 0.3637 |
Echinococcus multilocularis | hypoxanthine guanine phosphoribosyltransferase | 0.0189 | 0.3924 | 1 |
Loa Loa (eye worm) | runx1 | 0.0057 | 0.0936 | 0.0936 |
Toxoplasma gondii | NAC domain-containing protein | 0.0036 | 0.0454 | 0.1158 |
Schistosoma mansoni | hypoxanthine-guanine phosphoribosyltransferase | 0.0189 | 0.3924 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0025 | 0.0199 | 0.0507 |
Mycobacterium tuberculosis | Amidophosphoribosyltransferase PurF (glutamine phosphoribosylpyrophosphate amidotransferase) (ATASE) (gpatase) | 0.0044 | 0.064 | 0.1009 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0478 | 0.0749 |
Schistosoma mansoni | uracil phosphoribosyltransferase | 0.0044 | 0.064 | 0.1184 |
Schistosoma mansoni | hypoxanthine-guanine phosphoribosyltransferase | 0.0189 | 0.3924 | 1 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0025 | 0.0199 | 0.0507 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0025 | 0.0199 | 0.0507 |
Brugia malayi | Chain A, Human Glyoxalase Ii With Cacodylate And Acetate Ions Present In The Active Site. | 0.0033 | 0.0385 | 0.0189 |
Echinococcus granulosus | g protein coupled receptor | 0.0025 | 0.0199 | 0.0507 |
Mycobacterium tuberculosis | Probable penicillin-binding protein PbpA | 0.0074 | 0.1307 | 0.3637 |
Leishmania major | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative,OMPDCase-OPRTase, putative | 0.0044 | 0.064 | 0.0723 |
Trypanosoma cruzi | Adenine phosphoribosyltransferase, putative | 0.0044 | 0.064 | 0.0723 |
Schistosoma mansoni | hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) | 0.0033 | 0.0385 | 0.0498 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0025 | 0.0199 | 0.0507 |
Giardia lamblia | Guanine phosphoribosyltransferase | 0.0189 | 0.3924 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0298 | 0.0265 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0077 | 0.1373 | 0.3151 |
Trichomonas vaginalis | set domain proteins, putative | 0.0231 | 0.4884 | 1 |
Onchocerca volvulus | Putative hydrolase PNKD | 0.0033 | 0.0385 | 0.0189 |
Loa Loa (eye worm) | hydroxyacylglutathione hydrolase cytoplasmic | 0.0033 | 0.0385 | 0.0385 |
Wolbachia endosymbiont of Brugia malayi | cell division protein FtsI | 0.0074 | 0.1307 | 1 |
Trypanosoma cruzi | Adenine phosphoribosyltransferase, putative | 0.0044 | 0.064 | 0.0723 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0273 | 0.0697 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Mycobacterium ulcerans | bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 | 0.0074 | 0.1307 | 0.2605 |
Trypanosoma brucei | Voltage-dependent calcium channel subunit, putative | 0.0047 | 0.0693 | 0.0871 |
Schistosoma mansoni | voltage-gated cation channel | 0.0077 | 0.1373 | 0.3151 |
Trypanosoma cruzi | hypoxanthine-guanine phosphoribosyltransferase, putative | 0.0189 | 0.3924 | 1 |
Mycobacterium ulcerans | bifunctional penicillin-binding protein 1A/1B PonA1 | 0.0074 | 0.1307 | 0.2605 |
Echinococcus multilocularis | metallo beta lactamase domain containing protein | 0.0033 | 0.0385 | 0.0498 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0029 | 0.0298 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Mycobacterium ulcerans | bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase | 0.0044 | 0.064 | 0.0723 |
Echinococcus multilocularis | adenine phosphoribosyltransferase | 0.0044 | 0.064 | 0.1184 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0025 | 0.0199 | 0.0507 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0025 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0457 | 1 | 1 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0025 | 0.0199 | 0.0507 |
Echinococcus granulosus | orexin receptor type 2 | 0.0025 | 0.0199 | 0.0507 |
Treponema pallidum | adenine phosphoribosyltransferase | 0.0044 | 0.064 | 0.2774 |
Trypanosoma cruzi | hypoxanthine-guanine phosphoribosyltransferase, putative | 0.0189 | 0.3924 | 1 |
Plasmodium falciparum | hypoxanthine-guanine phosphoribosyltransferase | 0.0189 | 0.3924 | 1 |
Echinococcus granulosus | fmrfamide receptor | 0.0025 | 0.0199 | 0.0507 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0025 | 0.0199 | 0.0507 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0025 | 0.0199 | 0.0507 |
Trypanosoma cruzi | hypoxanthine-guanine phosphoribosyltransferase, putative | 0.0189 | 0.3924 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0025 | 0.0199 | 0.0507 |
Echinococcus granulosus | hydroxyacylglutathione hydrolase | 0.0033 | 0.0385 | 0.098 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0025 | 0.0199 | 0.0507 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0454 | 0.7467 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0478 | 0.0749 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0025 | 0.0199 | 0.0507 |
Echinococcus granulosus | adenine phosphoribosyltransferase | 0.0044 | 0.064 | 0.1632 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Brugia malayi | metallo-beta-lactamase superfamily protein | 0.0033 | 0.0385 | 0.0189 |
Mycobacterium ulcerans | adenine phosphoribosyltransferase | 0.0044 | 0.064 | 0.0723 |
Mycobacterium tuberculosis | Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase) (hypoxanthine phosphoribosyltransferase) (imp pyrophosphor | 0.0145 | 0.292 | 1 |
Treponema pallidum | penicillin-binding protein (pbp-3) | 0.0074 | 0.1307 | 1 |
Echinococcus multilocularis | Protein lozenge | 0.0057 | 0.0936 | 0.1979 |
Treponema pallidum | penicillin-binding protein (pbp-2) | 0.0074 | 0.1307 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.0298 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0385 | 0.0385 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0025 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Trypanosoma brucei | Adenine phosphoribosyltransferase, putative | 0.0044 | 0.064 | 0.0723 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0025 | 0.0199 | 0.0199 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0025 | 0.0199 | 0.0507 |
Echinococcus granulosus | g protein coupled receptor | 0.0025 | 0.0199 | 0.0507 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0385 | 0.0385 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Onchocerca volvulus | 0.0033 | 0.0385 | 0.0189 | |
Schistosoma mansoni | hypoxanthine-guanine phosphoribosyltransferase | 0.0044 | 0.064 | 0.1184 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0025 | 0.0199 | 0.0507 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1373 | 0.1373 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0454 | 0.0156 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0385 | 0.0385 |
Mycobacterium ulcerans | hypothetical protein | 0.0044 | 0.064 | 0.0723 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0077 | 0.1373 | 0.3151 |
Mycobacterium leprae | PROBABLE BIFUNCTIONAL MEMBRANE-ASSOCIATED PENICILLIN-BINDING PROTEIN 1A/1B PONA2 (MUREIN POLYMERASE) [INCLUDES: PENICILLIN-INSEN | 0.0074 | 0.1307 | 0.3637 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0454 | 0.0156 |
Mycobacterium tuberculosis | Adenine phosphoribosyltransferase Apt (APRT) (AMP diphosphorylase) (AMP pyrophosphorylase) (transphosphoribosidase) | 0.0044 | 0.064 | 0.1009 |
Brugia malayi | Phosphoribosyl transferase domain containing protein | 0.0189 | 0.3924 | 0.3801 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Onchocerca volvulus | 0.0029 | 0.0298 | 0.0101 | |
Mycobacterium leprae | PROBABLE OROTATE PHOSPHORIBOSYLTRANSFERASE PYRE (OPRT) (OPRTASE) | 0.0044 | 0.064 | 0.1009 |
Echinococcus granulosus | g protein coupled receptor | 0.0025 | 0.0199 | 0.0507 |
Echinococcus granulosus | voltage gated sodium channel Nav1 alpha subunit | 0.0032 | 0.0373 | 0.0951 |
Trypanosoma brucei | hypoxanthine-guanine phosphoribosyltransferase | 0.0189 | 0.3924 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0025 | 0.0199 | 0.0507 |
Schistosoma mansoni | Adenine phosphoribosyltransferase | 0.0044 | 0.064 | 0.1184 |
Trypanosoma cruzi | hypoxanthine-guanine phosphoribosyltransferase, putative | 0.0189 | 0.3924 | 1 |
Echinococcus multilocularis | ETHE1 protein | 0.0033 | 0.0385 | 0.0498 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0036 | 0.0454 | 0.7467 |
Echinococcus granulosus | metallo beta lactamase domain containing protein | 0.0033 | 0.0385 | 0.098 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0025 | 0.0199 | 0.0507 |
Loa Loa (eye worm) | calcium channel | 0.0077 | 0.1373 | 0.1373 |
Brugia malayi | ethe1-prov protein | 0.0033 | 0.0385 | 0.0189 |
Schistosoma mansoni | zinc phosphodiesterase | 0.0033 | 0.0385 | 0.0498 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0036 | 0.0454 | 0.0198 |
Trichomonas vaginalis | ribose-phosphate pyrophosphokinase, putative | 0.0044 | 0.064 | 0.0569 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Mycobacterium leprae | PROBABLE BIFUNCTIONAL PENICILLIN-BINDING PROTEIN 1A/1B PONA1 (MUREIN POLYMERASE) (PBP1): PENICILLIN-INSENSITIVE TRANSGLYCOSYLASE | 0.0074 | 0.1307 | 0.3637 |
Trypanosoma cruzi | Adenine phosphoribosyltransferase, putative | 0.0044 | 0.064 | 0.0723 |
Trypanosoma cruzi | Voltage-dependent calcium channel subunit, putative | 0.0047 | 0.0693 | 0.0871 |
Echinococcus granulosus | allatostatin A receptor | 0.0025 | 0.0199 | 0.0507 |
Mycobacterium leprae | Probable penicillin-binding protein PbpA | 0.0074 | 0.1307 | 0.3637 |
Echinococcus granulosus | transcription factor btf3 | 0.0036 | 0.0454 | 0.1158 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0025 | 0.0199 | 0.0199 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0025 | 0.0199 | 0.0507 |
Trypanosoma brucei | hypoxanthine-guanine phosphoribosyltransferase | 0.0189 | 0.3924 | 1 |
Giardia lamblia | Adenine phosphoribosyltransferase | 0.0044 | 0.064 | 0.0723 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Schistosoma mansoni | orotidine 5'-phosphate decarboxylase | 0.0044 | 0.064 | 0.1184 |
Leishmania major | hypoxanthine-guanine phosphoribosyltransferase | 0.0189 | 0.3924 | 1 |
Echinococcus multilocularis | zinc phosphodiesterase | 0.0033 | 0.0385 | 0.0498 |
Echinococcus multilocularis | metallo beta lactamase domain containing protein | 0.0033 | 0.0385 | 0.0498 |
Echinococcus multilocularis | hydroxyacylglutathione hydrolase | 0.0033 | 0.0385 | 0.0498 |
Echinococcus multilocularis | hypoxanthine guanine phosphoribosyltransferase | 0.0189 | 0.3924 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Wolbachia endosymbiont of Brugia malayi | amidophosphoribosyltransferase | 0.0044 | 0.064 | 0.2774 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0385 | 0.0189 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Onchocerca volvulus | 0.0231 | 0.4884 | 0.478 | |
Onchocerca volvulus | Adenine phosphoribosyltransferase homolog | 0.0044 | 0.064 | 0.045 |
Schistosoma mansoni | Adenine phosphoribosyltransferase | 0.0044 | 0.064 | 0.1184 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0025 | 0.0199 | 0.0507 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | ICD-1 protein | 0.0036 | 0.0454 | 0.0454 |
Wolbachia endosymbiont of Brugia malayi | orotate phosphoribosyltransferase | 0.0044 | 0.064 | 0.2774 |
Mycobacterium ulcerans | penicillin-binding lipoprotein | 0.0074 | 0.1307 | 0.2605 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0385 | 0.0498 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0077 | 0.1373 | 0.3151 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0385 | 0.0498 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Echinococcus granulosus | neuropeptide s receptor | 0.0025 | 0.0199 | 0.0507 |
Treponema pallidum | hypothetical protein | 0.0044 | 0.064 | 0.2774 |
Brugia malayi | Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog | 0.0077 | 0.1373 | 0.1198 |
Echinococcus granulosus | uridine 5' monophosphate synthase | 0.0044 | 0.064 | 0.1632 |
Mycobacterium tuberculosis | Conserved protein | 0.0044 | 0.064 | 0.1009 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0036 | 0.0454 | 0.0198 |
Echinococcus multilocularis | uridine 5' monophosphate synthase | 0.0044 | 0.064 | 0.1184 |
Trichomonas vaginalis | Ribose-phosphate pyrophosphokinase, putative | 0.0044 | 0.064 | 0.0569 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0478 | 0.0285 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0298 | 0.0265 |
Chlamydia trachomatis | transglycolase/transpeptidase | 0.0074 | 0.1307 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Toxoplasma gondii | orotate phosphoribosyltransferase | 0.0044 | 0.064 | 0.1632 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0478 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0025 | 0.0199 | 0.0199 |
Brugia malayi | orotate phosphoribosyltransferase family protein | 0.0044 | 0.064 | 0.045 |
Loa Loa (eye worm) | metallo-beta-lactamase superfamily protein | 0.0033 | 0.0385 | 0.0385 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 | 0.0077 | 0.1373 | 0.3498 |
Mycobacterium ulcerans | hypoxanthine-guanine phosphoribosyltransferase Hpt | 0.0189 | 0.3924 | 1 |
Mycobacterium leprae | AMIDOPHOSPHORIBOSYLTRANSFERASE PURF (GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE) (ATASE) (GPATASE) | 0.0044 | 0.064 | 0.1009 |
Echinococcus granulosus | ETHE1 protein | 0.0033 | 0.0385 | 0.098 |
Trypanosoma cruzi | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0044 | 0.064 | 0.0723 |
Onchocerca volvulus | 0.0457 | 1 | 1 | |
Leishmania major | basic transcription factor 3a, putative | 0.0036 | 0.0454 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0298 | 0.0759 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0044 | 0.064 | 0.1009 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0025 | 0.0199 | 0.0507 |
Trypanosoma brucei | Adenine phosphoribosyltransferase, putative | 0.0044 | 0.064 | 0.0723 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0298 | 0.0298 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0025 | 0.0199 | 0.0199 |
Toxoplasma gondii | hypoxanthine-xanthine-guanine phosphoribosyl transferase HXGPRT | 0.0189 | 0.3924 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0025 | 0.0199 | 0.0199 |
Trypanosoma brucei | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0044 | 0.064 | 0.0723 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0025 | 0.0199 | 0.0199 |
Echinococcus granulosus | hypothetical protein | 0.0025 | 0.0199 | 0.0507 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0385 | 0.0385 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu | 0.0077 | 0.1373 | 0.3498 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0036 | 0.0454 | 0.0198 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Echinococcus granulosus | g-protein coupled receptor | 0.0025 | 0.0199 | 0.0507 |
Onchocerca volvulus | Hydroxyacylglutathione hydrolase, mitochondrial homolog | 0.0033 | 0.0385 | 0.0189 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Echinococcus granulosus | hypoxanthine guanine phosphoribosyltransferase | 0.0189 | 0.3924 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Trichomonas vaginalis | hypoxanthine-guanine phosphoribosyltransferase, putative | 0.0189 | 0.3924 | 0.7868 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0025 | 0.0199 | 0.0507 |
Brugia malayi | Pre-SET motif family protein | 0.0203 | 0.4247 | 0.413 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0036 | 0.0454 | 0.0198 |
Mycobacterium ulcerans | orotate phosphoribosyltransferase | 0.0044 | 0.064 | 0.0723 |
Treponema pallidum | penicillin-binding protein (pbp-1) | 0.0074 | 0.1307 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Brugia malayi | metallo-beta-lactamase superfamily protein | 0.0033 | 0.0385 | 0.0189 |
Plasmodium vivax | hydroxyacyl glutathione hydrolase, putative | 0.0033 | 0.0385 | 0.0239 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0025 | 0.0199 | 0.0507 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0025 | 0.0199 | 0.0507 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0298 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0203 | 0.4247 | 0.4247 |
Mycobacterium ulcerans | penicillin-binding membrane protein PbpB | 0.0074 | 0.1307 | 0.2605 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0478 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0478 | 1 |
Loa Loa (eye worm) | adenine phosphoribosyltransferase | 0.0044 | 0.064 | 0.064 |
Echinococcus granulosus | neuropeptide receptor | 0.0025 | 0.0199 | 0.0507 |
Echinococcus granulosus | somatostatin receptor | 0.0025 | 0.0199 | 0.0507 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0025 | 0.0199 | 0.0507 |
Mycobacterium ulcerans | amidophosphoribosyltransferase | 0.0044 | 0.064 | 0.0723 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Mycobacterium ulcerans | penicillin-binding protein PbpA | 0.0074 | 0.1307 | 0.2605 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0025 | 0.0199 | 0.0507 |
Schistosoma mansoni | zinc phosphodiesterase | 0.0033 | 0.0385 | 0.0498 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0025 | 0.0199 | 0.0507 |
Chlamydia trachomatis | transglycolase/transpeptidase | 0.0074 | 0.1307 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0044 | 0.064 | 0.1009 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0025 | 0.0199 | 0.0507 |
Mycobacterium leprae | Probable hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase) (hypoxanthine phosphoribosyltransferase) (IMP pho | 0.0145 | 0.292 | 1 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0025 | 0.0199 | 0.0507 |
Schistosoma mansoni | hypoxanthine-guanine phosphoribosyltransferase | 0.0044 | 0.064 | 0.1184 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Toxoplasma gondii | hydroxyacylglutathione hydrolase | 0.0033 | 0.0385 | 0.098 |
Echinococcus granulosus | metallo beta lactamase domain containing protein | 0.0033 | 0.0385 | 0.098 |
Trypanosoma cruzi | orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | 0.0044 | 0.064 | 0.0723 |
Loa Loa (eye worm) | hypothetical protein | 0.0457 | 1 | 1 |
Plasmodium vivax | hypoxanthine-guanine phosphoribosyltransferase, putative | 0.0189 | 0.3924 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0298 | 0.0265 |
Schistosoma mansoni | high voltage-activated calcium channel Cav2A | 0.0077 | 0.1373 | 0.3151 |
Leishmania major | adenine phosphoribosyltransferase | 0.0044 | 0.064 | 0.0723 |
Mycobacterium tuberculosis | Probable bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 (murein polymerase) [includes: penicillin-insen | 0.0074 | 0.1307 | 0.3637 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0025 | 0.0199 | 0.0507 |
Toxoplasma gondii | metallo-beta-lactamase domain-containing protein | 0.0033 | 0.0385 | 0.098 |
Echinococcus multilocularis | sodium channel protein | 0.0032 | 0.0373 | 0.0467 |
Trypanosoma cruzi | Adenine phosphoribosyltransferase, putative | 0.0044 | 0.064 | 0.0723 |
Echinococcus granulosus | neuropeptide receptor | 0.0025 | 0.0199 | 0.0507 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0077 | 0.1373 | 0.3151 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0025 | 0.0199 | 0.0507 |
Leishmania major | xanthine phosphoribosyltransferase | 0.0189 | 0.3924 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0298 | 0.0759 |
Treponema pallidum | phosphoribosylpyrophosphate synthetase | 0.0044 | 0.064 | 0.2774 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0077 | 0.1373 | 0.3151 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0025 | 0.0199 | 0.0199 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0077 | 0.1373 | 0.3498 |
Mycobacterium tuberculosis | Probable pyrimidine operon regulatory protein PyrR | 0.0044 | 0.064 | 0.1009 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0025 | 0.0199 | 0.0507 |
Echinococcus granulosus | zinc phosphodiesterase | 0.0033 | 0.0385 | 0.098 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0025 | 0.0199 | 0.0507 |
Mycobacterium tuberculosis | Possible penicillin-binding lipoprotein | 0.0074 | 0.1307 | 0.3637 |
Echinococcus granulosus | voltage dependent L type calcium channel subunit|voltage dependent calcium channel | 0.0077 | 0.1373 | 0.3498 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0478 | 1 |
Brugia malayi | Adenine phosphoribosyltransferase | 0.0044 | 0.064 | 0.045 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0077 | 0.1373 | 0.3151 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0454 | 0.0156 |
Plasmodium vivax | orotate phosphoribosyltransferase, putative | 0.0044 | 0.064 | 0.0945 |
Schistosoma mansoni | high voltage-activated calcium channel Cav1 | 0.0077 | 0.1373 | 0.3151 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0199 | 0.0199 |
Loa Loa (eye worm) | hydroxyacylglutathione hydrolase | 0.0033 | 0.0385 | 0.0385 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0478 | 0.0749 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Relative activity (functional) | = 2.4 | In Vitro relative activity against Plasmodium falciparum W-2 clone (chloroquine-resistant and mefloquine-sensitive). | ChEMBL. | 11063619 |
Relative activity (functional) | = 2.5 | In Vitro relative activity against Plasmodium falciparum D-6 clone (chloroquine-sensitive and mefloquine -resistant). | ChEMBL. | 11063619 |
Relative activity (functional) | = 3.1 | In Vitro relative activity against Plasmodium falciparum W-2 clone (chloroquine-resistant and mefloquine-sensitive). | ChEMBL. | 11063619 |
Relative activity (functional) | = 3.1 | In Vitro relative activity against Plasmodium falciparum D-6 clone (chloroquine-sensitive and mefloquine -resistant). | ChEMBL. | 11063619 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.