Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0076 | 0.0614 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0051 | 0.0294 | 0.4795 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0023 | 0.0085 |
Onchocerca volvulus | Putative nachr subunit | 0.0057 | 0.0368 | 0.1091 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0057 | 0.0368 | 0.0345 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0057 | 0.0368 | 0.1338 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0368 | 0.1338 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0057 | 0.0368 | 0.1338 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0057 | 0.0368 | 0.1338 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0034 | 0.007 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0023 | 0.0085 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.1868 | 0.6789 |
Plasmodium vivax | SET domain protein, putative | 0.0034 | 0.007 | 0.4302 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0368 | 0.1338 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0368 | 0.1338 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0023 | 0.0085 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0239 | 0.2751 | 1 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0041 | 0.0162 | 0.0139 |
Loa Loa (eye worm) | ACC-1 protein | 0.0057 | 0.0368 | 0.1338 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0051 | 0.0294 | 0.107 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0057 | 0.0368 | 0.0345 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0057 | 0.0368 | 0.0345 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0368 | 0.1338 |
Leishmania major | hypothetical protein, conserved | 0.0041 | 0.0162 | 0.2646 |
Leishmania major | DNA polymerase eta, putative | 0.0051 | 0.0294 | 0.4795 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0057 | 0.0368 | 0.0345 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0034 | 0.007 | 0.0047 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.007 | 0.0534 | 1 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0057 | 0.0368 | 0.0345 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0368 | 0.1338 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0057 | 0.0368 | 0.0345 |
Schistosoma mansoni | nAChR subunit | 0.0057 | 0.0368 | 0.0345 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0 | 0.5 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0057 | 0.0368 | 0.0345 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0057 | 0.0368 | 0.0345 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0036 | 0.0094 | 0.1762 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0057 | 0.0368 | 0.1338 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0368 | 0.1338 |
Toxoplasma gondii | ABC1 family protein | 0.0041 | 0.0162 | 0.304 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0041 | 0.0162 | 0.059 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.007 | 0.0534 | 1 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0057 | 0.0368 | 0.1338 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0057 | 0.0368 | 0.1338 |
Echinococcus granulosus | muscleblind protein | 0.0172 | 0.1868 | 0.1849 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0057 | 0.0368 | 0.0345 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.007 | 0.0047 |
Schistosoma mansoni | nAChR subunit | 0.0057 | 0.0368 | 0.0345 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0076 | 0.0614 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0162 | 0.059 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0023 | 0.0085 |
Schistosoma mansoni | DNA polymerase eta | 0.0051 | 0.0294 | 0.0272 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0368 | 0.1338 |
Brugia malayi | beta-lactamase family protein | 0.0041 | 0.0162 | 0.059 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0057 | 0.0368 | 0.0345 |
Plasmodium vivax | hypothetical protein, conserved | 0.0041 | 0.0162 | 1 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0057 | 0.0368 | 0.0345 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0064 | 0.0231 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0057 | 0.0368 | 0.0345 |
Echinococcus multilocularis | muscleblind protein | 0.0172 | 0.1868 | 0.1849 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0057 | 0.0368 | 0.1338 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0057 | 0.0368 | 0.0345 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0057 | 0.0368 | 0.1338 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0076 | 0.0614 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0031 | 0.0023 | 0.0085 |
Brugia malayi | Muscleblind-like protein | 0.0172 | 0.1868 | 0.6789 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0057 | 0.0368 | 0.1338 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0076 | 0.0614 | 0.0592 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0368 | 0.1338 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0057 | 0.0368 | 0.1338 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0057 | 0.0368 | 0.0345 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0041 | 0.0162 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0162 | 0.059 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0023 | 0.0085 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0051 | 0.0294 | 0.4795 |
Echinococcus granulosus | nAChR subunit | 0.0057 | 0.0368 | 0.0345 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0057 | 0.0368 | 0.0345 |
Echinococcus granulosus | dna polymerase eta | 0.0051 | 0.0294 | 0.0272 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0064 | 0.0231 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0031 | 0.0023 | 0.0085 |
Loa Loa (eye worm) | beta-lactamase | 0.0041 | 0.0162 | 0.059 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0268 | 0.0976 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0057 | 0.0368 | 0.1338 |
Echinococcus multilocularis | dna polymerase eta | 0.0051 | 0.0294 | 0.0272 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0057 | 0.0368 | 0.1338 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.007 | 0.0534 | 0.8703 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0368 | 0.1338 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0023 | 0.0085 |
Onchocerca volvulus | 0.0057 | 0.0368 | 0.1091 | |
Echinococcus multilocularis | nAChR subunit | 0.0057 | 0.0368 | 0.0345 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0294 | 0.107 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0076 | 0.0614 | 0.2231 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0162 | 0.2646 |
Schistosoma mansoni | nAChR subunit | 0.0057 | 0.0368 | 0.0345 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0036 | 0.0094 | 0.1533 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0034 | 0.007 | 0.0047 |
Brugia malayi | hypothetical protein | 0.0174 | 0.1894 | 0.6883 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0057 | 0.0368 | 0.0345 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0057 | 0.0368 | 0.1338 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0057 | 0.0368 | 0.1338 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0268 | 0.0976 |
Onchocerca volvulus | 0.0034 | 0.007 | 0.0147 | |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.1868 | 0.6789 |
Schistosoma mansoni | nAChR subunit | 0.0057 | 0.0368 | 0.0345 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0041 | 0.0162 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0162 | 0.059 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0368 | 0.1338 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.007 | 0.0534 | 0.0512 |
Brugia malayi | Cation transporter family protein | 0.0057 | 0.0368 | 0.1338 |
Onchocerca volvulus | 0.0057 | 0.0368 | 0.1091 | |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0023 | 0.0085 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0064 | 0.004 |
Mycobacterium leprae | conserved hypothetical protein | 0.0041 | 0.0162 | 0.5 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0057 | 0.0368 | 0.1338 |
Brugia malayi | Cation transporter family protein | 0.0057 | 0.0368 | 0.1338 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0162 | 0.059 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0 | 0.5 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0057 | 0.0368 | 0.0345 |
Loa Loa (eye worm) | GABA receptor subunit | 0.0031 | 0.0023 | 0.0085 |
Onchocerca volvulus | 0.0041 | 0.0162 | 0.044 | |
Brugia malayi | beta-lactamase | 0.0041 | 0.0162 | 0.059 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0034 | 0.007 | 0.1308 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1192 | 0.4333 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0368 | 0.1338 |
Brugia malayi | Pre-SET motif family protein | 0.0034 | 0.007 | 0.0254 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.007 | 0.0254 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0057 | 0.0368 | 0.1338 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0033 | 0.0053 | 0.003 |
Onchocerca volvulus | 0.0174 | 0.1894 | 0.5918 | |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0076 | 0.0614 | 0.0592 |
Brugia malayi | Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein | 0.012 | 0.1192 | 0.4333 |
Onchocerca volvulus | 0.0041 | 0.0162 | 0.044 | |
Trypanosoma brucei | hypothetical protein, conserved | 0.0041 | 0.0162 | 0.2646 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0368 | 0.1338 |
Echinococcus granulosus | peptidyl glycine alpha amidating monooxygenase | 0.012 | 0.1192 | 0.1171 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0368 | 0.1338 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0057 | 0.0368 | 0.0345 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0057 | 0.0368 | 0.0345 |
Brugia malayi | beta-lactamase family protein | 0.0041 | 0.0162 | 0.059 |
Loa Loa (eye worm) | LGC-31 protein | 0.0057 | 0.0368 | 0.1338 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0076 | 0.0614 | 0.2231 |
Mycobacterium leprae | Probable lipase LipE | 0.0041 | 0.0162 | 0.5 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0057 | 0.0368 | 0.0345 |
Onchocerca volvulus | 0.0272 | 0.3184 | 1 | |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0076 | 0.0614 | 1 |
Schistosoma mansoni | peptidylglycine monooxygenase | 0.012 | 0.1192 | 0.1171 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0368 | 0.1338 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.007 | 0.0534 | 0.0512 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0264 | 0.3081 | 1 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.007 | 0.0534 | 1 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.007 | 0.0534 | 0.1274 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0057 | 0.0368 | 0.0345 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.007 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0368 | 0.1338 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0057 | 0.0368 | 0.0345 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0057 | 0.0368 | 0.1338 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0057 | 0.0368 | 0.0345 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.1894 | 0.6883 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0057 | 0.0368 | 0.0345 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0162 | 0.2646 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0172 | 0.1868 | 0.1849 |
Schistosoma mansoni | dopamine-beta-monooxygenase | 0.0227 | 0.2596 | 0.2578 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0793 | 1 | 1 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0041 | 0.0162 | 0.059 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0057 | 0.0368 | 0.0345 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0023 | 0.0085 |
Trichomonas vaginalis | set domain proteins, putative | 0.0272 | 0.3184 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0031 | 0.0023 | 0.0085 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0268 | 0.0976 |
Schistosoma mansoni | nAChR subunit | 0.0057 | 0.0368 | 0.0345 |
Onchocerca volvulus | 0.0057 | 0.0368 | 0.1091 | |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0057 | 0.0368 | 0.1338 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0076 | 0.0614 | 1 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0057 | 0.0368 | 0.0345 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0368 | 0.1338 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0057 | 0.0368 | 0.1338 |
Onchocerca volvulus | 0.0041 | 0.0162 | 0.044 | |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0034 | 0.007 | 0.0047 |
Schistosoma mansoni | nAChR subunit | 0.0057 | 0.0368 | 0.0345 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.007 | 0.0534 | 0.0512 |
Onchocerca volvulus | 0.0057 | 0.0368 | 0.1091 | |
Onchocerca volvulus | 0.0057 | 0.0368 | 0.1091 | |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.007 | 0.0047 |
Leishmania major | DNA polymerase eta, putative | 0.0036 | 0.0094 | 0.1533 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0057 | 0.0368 | 0.1338 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0076 | 0.0614 | 0.0592 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0057 | 0.0368 | 0.1338 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0041 | 0.0162 | 0.0139 |
Onchocerca volvulus | 0.0057 | 0.0368 | 0.1091 | |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0368 | 0.1338 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0044 | 0.0196 | 0.0173 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0793 | 1 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.007 | 0.0534 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0057 | 0.0368 | 0.0345 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0057 | 0.0368 | 0.0345 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.007 | 0.0534 | 0.0512 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0023 | 0.0085 |
Brugia malayi | Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein | 0.012 | 0.1192 | 0.4333 |
Echinococcus multilocularis | peptidyl glycine alpha amidating monooxygenase | 0.012 | 0.1192 | 0.1171 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0368 | 0.1338 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0057 | 0.0368 | 0.1338 |
Schistosoma mansoni | peptidyl-glycine monooxygenase | 0.012 | 0.1192 | 0.1171 |
Brugia malayi | Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein | 0.0059 | 0.0395 | 0.1435 |
Brugia malayi | Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein | 0.0061 | 0.0418 | 0.152 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0162 | 0.059 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0268 | 0.0976 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1192 | 0.4333 |
Brugia malayi | Cation transporter family protein | 0.0057 | 0.0368 | 0.1338 |
Loa Loa (eye worm) | ACC-1 protein | 0.0057 | 0.0368 | 0.1338 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0368 | 0.1338 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0057 | 0.0368 | 0.0345 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0031 | 0.0023 | 0.0085 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0057 | 0.0368 | 0.0345 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0057 | 0.0368 | 0.1338 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0057 | 0.0368 | 0.0345 |
Brugia malayi | Pre-SET motif family protein | 0.0239 | 0.2751 | 1 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0044 | 0.0196 | 0.0173 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0162 | 0.059 |
Schistosoma mansoni | nAChR subunit | 0.0057 | 0.0368 | 0.0345 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Behavior (functional) | 0 | General behavior in mice after oral administratin of the compound (500 mg/kg) using acute toxicity assay; Convulsions | ChEMBL. | 8386248 |
ED50 (functional) | = 10.6 mg kg-1 | Analgesic activity in mice using p-phenylquinone test. | ChEMBL. | 8386248 |
ED50 (functional) | = 10.6 mg kg-1 | Analgesic activity in mice using p-phenylquinone test. | ChEMBL. | 8386248 |
Inhibition (functional) | = 23 % | Anti-inflammatory effect expressed as % inhibition at 50 mg/kg in acute carrageenan paw edema test in rats | ChEMBL. | 8386248 |
Mortality (ADMET) | = 90 % | Percent mortality in mice after oral administratin of the compound (500 mg/kg) using acute toxicity assay | ChEMBL. | 8386248 |
Mortality (ADMET) | = 90 % | Percent mortality in mice after oral administratin of the compound (500 mg/kg) using acute toxicity assay | ChEMBL. | 8386248 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.