Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | cAMP-dependent protein kinase catalytic subunit 1 | 0.0606 | 0.4622 | 1 |
Toxoplasma gondii | AGC kinase | 0.0606 | 0.4622 | 1 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0279 | 0.198 | 0.1973 |
Schistosoma mansoni | protein kinase C mu | 0.0488 | 0.367 | 0.3645 |
Brugia malayi | diacylglycerol kinase | 0.0221 | 0.1509 | 0.1502 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0279 | 0.198 | 0.1973 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.0607 | 0.4627 | 0.4623 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0056 | 0.0173 | 0.0173 |
Echinococcus multilocularis | expressed conserved protein | 0.0055 | 0.0167 | 0.0167 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0607 | 0.4627 | 0.4606 |
Onchocerca volvulus | 0.0429 | 0.319 | 0.762 | |
Onchocerca volvulus | 0.0254 | 0.1778 | 0.0146 | |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0623 | 0.4755 | 0.4755 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0279 | 0.198 | 0.198 |
Loa Loa (eye worm) | RhoGAP domain-containing protein | 0.0225 | 0.1541 | 0.1534 |
Loa Loa (eye worm) | AGC/PKG protein kinase | 0.0055 | 0.0167 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.1751 | 0.1743 |
Entamoeba histolytica | protein kinase, putative | 0.0279 | 0.198 | 0.3197 |
Entamoeba histolytica | diacylglycerol kinase, putative | 0.0221 | 0.1509 | 0.2385 |
Toxoplasma gondii | AGC kinase | 0.0279 | 0.198 | 0.407 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0279 | 0.198 | 0.1973 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0279 | 0.198 | 0.198 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0113 | 0.0635 | 0.0598 |
Entamoeba histolytica | hypothetical protein | 0.0113 | 0.0635 | 0.0878 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0292 | 0.2083 | 0.2076 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0635 | 0.0627 |
Echinococcus multilocularis | raf serine:threonine protein kinase | 0.0222 | 0.1518 | 0.1518 |
Trypanosoma cruzi | cAMP-dependent protein kinase catalytic subunit 3 | 0.0606 | 0.4622 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.1509 | 0.1502 |
Echinococcus granulosus | axis inhibition protein axin | 0.0113 | 0.0635 | 0.0635 |
Echinococcus multilocularis | expressed protein | 0.0113 | 0.0635 | 0.0635 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.0301 | 0.2158 | 0.2158 |
Schistosoma mansoni | unc-13 (munc13) | 0.0254 | 0.1778 | 0.1745 |
Schistosoma mansoni | diacylglycerol kinase theta | 0.0221 | 0.1509 | 0.1476 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.0039 | 0.004 | 0.004 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0035 | 0.0009 | 0.0009 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0039 | 0.004 | 0.004 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0113 | 0.0635 | 0.0635 |
Echinococcus granulosus | cGMP dependent protein kinase | 0.0055 | 0.0167 | 0.0167 |
Echinococcus granulosus | NDR protein kinase | 0.0279 | 0.198 | 0.198 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0279 | 0.198 | 0.1948 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0279 | 0.198 | 0.1973 |
Loa Loa (eye worm) | AGC/PKA protein kinase | 0.0606 | 0.4622 | 0.4618 |
Brugia malayi | protein kinase C3,putative | 0.0323 | 0.2335 | 0.2328 |
Leishmania major | protein kinase A catalytic subunit isoform 1 | 0.0606 | 0.4622 | 1 |
Echinococcus multilocularis | cAMP dependent protein kinase catalytic subunit | 0.0606 | 0.4622 | 0.4622 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0619 | 0.4725 | 0.793 |
Loa Loa (eye worm) | G protein-coupled receptor kinase 1 | 0.0494 | 0.3716 | 0.3711 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0238 | 0.1643 | 0.161 |
Toxoplasma gondii | AGC kinase | 0.0606 | 0.4622 | 1 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0935 | 0.728 | 0.728 |
Toxoplasma gondii | diacylglycerol kinase, putative | 0.0221 | 0.1509 | 0.3013 |
Echinococcus multilocularis | serine:threonine protein kinase MRCK beta | 0.0238 | 0.1643 | 0.1643 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0279 | 0.198 | 0.198 |
Echinococcus granulosus | G protein coupled receptor kinase 1 | 0.0189 | 0.1247 | 0.1247 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.0494 | 0.3716 | 0.3711 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.0039 | 0.004 | 0.004 |
Echinococcus granulosus | guanine nucleotide exchange factor VAV2 | 0.0225 | 0.1541 | 0.1541 |
Trypanosoma brucei | protein kinase A catalytic subunit, putative | 0.0606 | 0.4622 | 1 |
Echinococcus granulosus | Rac GTPase activating protein 1 | 0.0221 | 0.1509 | 0.1509 |
Brugia malayi | PXA domain containing protein | 0.0113 | 0.0635 | 0.0627 |
Brugia malayi | Pleckstrin Homology Domain | 0.0234 | 0.1612 | 0.1605 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.1509 | 0.1502 |
Onchocerca volvulus | 0.0485 | 0.3639 | 1 | |
Echinococcus multilocularis | N chimaerin | 0.0225 | 0.1541 | 0.1541 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1272 | 1 | 1 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0279 | 0.198 | 0.1973 |
Trypanosoma cruzi | cAMP-dependent protein kinase catalytic subunit 3 | 0.0606 | 0.4622 | 1 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0623 | 0.4755 | 0.4755 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.0039 | 0.004 | 0.004 |
Echinococcus multilocularis | Diacylglycerol kinase theta | 0.0221 | 0.1509 | 0.1509 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.1272 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0292 | 0.2083 | 0.3374 |
Trichomonas vaginalis | AGC family protein kinase | 0.0279 | 0.198 | 0.3374 |
Trichomonas vaginalis | AGC family protein kinase | 0.0292 | 0.2083 | 0.3632 |
Echinococcus granulosus | unc 13 munc13 | 0.0254 | 0.1778 | 0.1778 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0113 | 0.0635 | 0.0635 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0113 | 0.0635 | 0.0635 |
Brugia malayi | regulator of G-protein signaling rgs-7 | 0.0113 | 0.0635 | 0.0627 |
Echinococcus granulosus | C2 calcium dependent membrane targeting | 0.0254 | 0.1778 | 0.1778 |
Entamoeba histolytica | hypothetical protein | 0.0113 | 0.0635 | 0.0878 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0635 | 0.0627 |
Echinococcus multilocularis | A kinase anchor protein 10, mitochondrial | 0.0113 | 0.0635 | 0.0635 |
Brugia malayi | Protein kinase domain containing protein | 0.0238 | 0.1643 | 0.1636 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.0607 | 0.4627 | 0.4623 |
Schistosoma mansoni | regulator of G protein signaling | 0.0113 | 0.0635 | 0.0598 |
Brugia malayi | Protein kinase c protein 2 | 0.0894 | 0.6942 | 0.694 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0279 | 0.198 | 0.1948 |
Echinococcus granulosus | protein kinase c iota type | 0.0586 | 0.4457 | 0.4457 |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.0301 | 0.2158 | 0.2158 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.1018 | 0.7946 | 0.7946 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0755 | 0.5823 | 0.5823 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.005 | 0.0127 | 0.0118 |
Brugia malayi | Hr1 repeat family protein | 0.0279 | 0.198 | 0.1973 |
Brugia malayi | cAMP-dependent protein kinase catalytic subunit, putative | 0.0606 | 0.4622 | 0.4618 |
Echinococcus multilocularis | protein kinase c eta type | 0.0221 | 0.1509 | 0.1509 |
Trichomonas vaginalis | AGC family protein kinase | 0.0292 | 0.2083 | 0.3632 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0279 | 0.198 | 0.198 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.1272 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0292 | 0.2083 | 0.3632 |
Echinococcus multilocularis | G protein coupled receptor kinase 1 | 0.0189 | 0.1247 | 0.1247 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0279 | 0.198 | 0.198 |
Echinococcus multilocularis | regulator of G protein signaling | 0.0113 | 0.0635 | 0.0635 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.0039 | 0.004 | 0.004 |
Loa Loa (eye worm) | raf kinase | 0.0221 | 0.1509 | 0.1502 |
Echinococcus multilocularis | myotubularin protein 13 | 0.0234 | 0.1612 | 0.1612 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0113 | 0.0635 | 0.0635 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0113 | 0.0635 | 0.0598 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0035 | 0.0009 | 0.0009 |
Brugia malayi | Variant SH3 domain containing protein | 0.0225 | 0.1541 | 0.1534 |
Trichomonas vaginalis | AGC family protein kinase | 0.0292 | 0.2083 | 0.3632 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0606 | 0.4622 | 0.4601 |
Brugia malayi | hypothetical protein | 0.0113 | 0.0635 | 0.0627 |
Brugia malayi | Protein kinase domain containing protein | 0.0279 | 0.198 | 0.1973 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.1509 | 0.1502 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.1156 | 0.9065 | 0.9065 |
Echinococcus multilocularis | Rac GTPase activating protein 1 | 0.0221 | 0.1509 | 0.1509 |
Brugia malayi | SRC-1 | 0.0039 | 0.004 | 0.0031 |
Leishmania major | protein kinase A catalytic subunit | 0.0606 | 0.4622 | 1 |
Schistosoma mansoni | regulator of G protein signaling | 0.0113 | 0.0635 | 0.0598 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.0301 | 0.2158 | 0.2151 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0113 | 0.0635 | 0.0627 |
Entamoeba histolytica | hypothetical protein | 0.0221 | 0.1509 | 0.2385 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0279 | 0.198 | 0.1973 |
Echinococcus granulosus | N chimaerin | 0.0225 | 0.1541 | 0.1541 |
Schistosoma mansoni | serine/threonine kinase | 0.0279 | 0.198 | 0.1948 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0673 | 0.5157 | 0.5152 |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.0488 | 0.367 | 0.3664 |
Schistosoma mansoni | hypothetical protein | 0.0221 | 0.1509 | 0.1476 |
Brugia malayi | A-kinase anchor protein 10, precursor | 0.0113 | 0.0635 | 0.0627 |
Echinococcus multilocularis | cGMP dependent protein kinase 1 | 0.0055 | 0.0167 | 0.0167 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0113 | 0.0635 | 0.0627 |
Schistosoma mansoni | regulator of G protein signaling | 0.0113 | 0.0635 | 0.0598 |
Echinococcus granulosus | protein kinase C gamma type | 0.0935 | 0.728 | 0.728 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0635 | 0.0627 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0039 | 0.004 | 0.004 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0238 | 0.1643 | 0.161 |
Schistosoma mansoni | atypical protein kinase C | 0.0592 | 0.4508 | 0.4486 |
Schistosoma mansoni | chimerin-related rho-gtpase-activating protein | 0.0225 | 0.1541 | 0.1507 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0279 | 0.198 | 0.198 |
Trichomonas vaginalis | AGC family protein kinase | 0.0279 | 0.198 | 0.3374 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0113 | 0.0635 | 0.0635 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1156 | 0.9065 | 0.9062 |
Entamoeba histolytica | protein kinase, putative | 0.0292 | 0.2083 | 0.3374 |
Brugia malayi | PXA domain containing protein | 0.0113 | 0.0635 | 0.0627 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0606 | 0.4622 | 0.4601 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.0494 | 0.3716 | 0.3711 |
Brugia malayi | Protein kinase domain containing protein | 0.0279 | 0.198 | 0.1973 |
Plasmodium falciparum | cAMP-dependent protein kinase catalytic subunit | 0.0606 | 0.4622 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0039 | 0.004 | 0.004 |
Brugia malayi | RhoGAP domain containing protein | 0.0221 | 0.1509 | 0.1502 |
Schistosoma mansoni | regulator of G protein signaling | 0.0113 | 0.0635 | 0.0598 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.0039 | 0.004 | 0.004 |
Loa Loa (eye worm) | AGC/PKC/IOTA protein kinase | 0.0329 | 0.2385 | 0.2379 |
Brugia malayi | Ras association domain family 1 isoform A | 0.0221 | 0.1509 | 0.1502 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0635 | 0.0627 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0606 | 0.4622 | 0.4601 |
Loa Loa (eye worm) | hypothetical protein | 0.0708 | 0.5446 | 0.5442 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0035 | 0.0009 | 0.0009 |
Trypanosoma cruzi | cAMP-dependent protein kinase catalytic subunit 2 | 0.0606 | 0.4622 | 1 |
Echinococcus multilocularis | C2 calcium dependent membrane targeting | 0.0254 | 0.1778 | 0.1778 |
Trichomonas vaginalis | AGC family protein kinase | 0.0292 | 0.2083 | 0.3632 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0113 | 0.0635 | 0.0635 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0279 | 0.198 | 0.1973 |
Echinococcus granulosus | cAMP dependent protein kinase catalytic subunit | 0.0606 | 0.4622 | 0.4622 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0113 | 0.0635 | 0.0635 |
Schistosoma mansoni | protein kinase C | 0.0254 | 0.1778 | 0.1745 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0055 | 0.0167 | 0.0128 |
Brugia malayi | Egg laying defective protein 4 | 0.0055 | 0.0167 | 0.0158 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.1156 | 0.9065 | 0.9065 |
Schistosoma mansoni | chimerin-related rho-gtpase-activating protein | 0.0225 | 0.1541 | 0.1507 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0113 | 0.0635 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0635 | 0.0627 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0035 | 0.0009 | 0.0009 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.0039 | 0.004 | 0.004 |
Schistosoma mansoni | regulator of G protein signaling 3 rgs3 | 0.0113 | 0.0635 | 0.0598 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0039 | 0.004 | 0.004 |
Echinococcus granulosus | Serine/threonine-protein kinase Genghis Khan | 0.0238 | 0.1643 | 0.1643 |
Echinococcus granulosus | cGMP dependent protein kinase 1 | 0.0055 | 0.0167 | 0.0167 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0279 | 0.198 | 0.1948 |
Echinococcus multilocularis | cAMP dependent protein kinase catalytic subunit | 0.0606 | 0.4622 | 0.4622 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0768 | 0.5925 | 1 |
Echinococcus granulosus | cAMP dependent protein kinase catalytic subunit | 0.0606 | 0.4622 | 0.4622 |
Entamoeba histolytica | hypothetical protein | 0.0392 | 0.2894 | 0.4773 |
Brugia malayi | Variant SH3 domain containing protein | 0.005 | 0.0127 | 0.0118 |
Echinococcus granulosus | [G-protein-coupledreceptor] kinase | 0.0494 | 0.3716 | 0.3716 |
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.1612 | 0.1605 |
Brugia malayi | Protein kinase domain containing protein | 0.0292 | 0.2083 | 0.2076 |
Echinococcus multilocularis | intersectin 2 | 0.0037 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.0267 | 0.1884 | 0.1877 |
Brugia malayi | hypothetical protein | 0.0113 | 0.0635 | 0.0627 |
Echinococcus multilocularis | protein kinase c iota type | 0.0586 | 0.4457 | 0.4457 |
Loa Loa (eye worm) | RasGEF domain-containing protein | 0.0221 | 0.1509 | 0.1502 |
Trichomonas vaginalis | AGC family protein kinase | 0.0292 | 0.2083 | 0.3632 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.1509 | 0.1502 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.0039 | 0.004 | 0.004 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0055 | 0.0167 | 0.0128 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0292 | 0.2083 | 0.4466 |
Echinococcus multilocularis | cAMP dependent protein kinase catalytic subunit | 0.0606 | 0.4622 | 0.4622 |
Loa Loa (eye worm) | RGS-3 protein | 0.0113 | 0.0635 | 0.0627 |
Mycobacterium ulcerans | hypothetical protein | 0.0038 | 0.0034 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0292 | 0.2083 | 0.3632 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0222 | 0.1518 | 0.1485 |
Loa Loa (eye worm) | SRC-1 | 0.0039 | 0.004 | 0.0031 |
Trypanosoma cruzi | cAMP-dependent protein kinase catalytic subunit 1 | 0.0606 | 0.4622 | 1 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0113 | 0.0635 | 0.0635 |
Echinococcus granulosus | myotubularin protein 13 | 0.0234 | 0.1612 | 0.1612 |
Echinococcus granulosus | Diacylglycerol kinase theta | 0.0221 | 0.1509 | 0.1509 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1156 | 0.9065 | 0.9062 |
Onchocerca volvulus | 0.0472 | 0.3536 | 0.9456 | |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0619 | 0.4725 | 0.793 |
Loa Loa (eye worm) | hypothetical protein | 0.0485 | 0.3639 | 0.3633 |
Giardia lamblia | Kinase, AGC PKA | 0.0606 | 0.4622 | 0.5 |
Brugia malayi | RhoGEF domain containing protein | 0.0221 | 0.1509 | 0.1502 |
Brugia malayi | C1-like domain containing protein | 0.0488 | 0.367 | 0.3664 |
Entamoeba histolytica | diacylglycerol kinase, putative | 0.0221 | 0.1509 | 0.2385 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.1751 | 0.1743 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0301 | 0.2158 | 0.2126 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.0039 | 0.004 | 0.004 |
Echinococcus multilocularis | enhancer of mRNA decapping protein 4 | 0.059 | 0.4489 | 0.4489 |
Schistosoma mansoni | rac gtpase activating protein | 0.0221 | 0.1509 | 0.1476 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0113 | 0.0635 | 0.0598 |
Loa Loa (eye worm) | Ras association domain family 1 isoform A | 0.0221 | 0.1509 | 0.1502 |
Echinococcus multilocularis | guanine nucleotide exchange factor VAV2 | 0.0225 | 0.1541 | 0.1541 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0635 | 0.0627 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0623 | 0.4755 | 0.4755 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0279 | 0.198 | 0.198 |
Echinococcus multilocularis | Regulator of G protein signaling 20 | 0.0113 | 0.0635 | 0.0635 |
Loa Loa (eye worm) | AGC/PKA protein kinase | 0.0606 | 0.4622 | 0.4618 |
Entamoeba histolytica | hypothetical protein | 0.0113 | 0.0635 | 0.0878 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0221 | 0.1509 | 0.1502 |
Trichomonas vaginalis | AGC family protein kinase | 0.0606 | 0.4622 | 1 |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0035 | 0.0009 | 0.0009 |
Echinococcus multilocularis | cAMP dependent protein kinase catalytic subunit | 0.0606 | 0.4622 | 0.4622 |
Schistosoma mansoni | vav2 | 0.0238 | 0.1644 | 0.1611 |
Brugia malayi | diacylglycerol kinase | 0.0221 | 0.1509 | 0.1502 |
Schistosoma mansoni | regulator of G protein signaling | 0.0113 | 0.0635 | 0.0598 |
Trichomonas vaginalis | AGC family protein kinase | 0.0279 | 0.198 | 0.3374 |
Schistosoma mansoni | protein kinase C mu | 0.0221 | 0.1509 | 0.1476 |
Echinococcus granulosus | expressed protein | 0.0113 | 0.0635 | 0.0635 |
Brugia malayi | RhoGAP domain containing protein | 0.0225 | 0.1541 | 0.1534 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0301 | 0.2158 | 0.2126 |
Echinococcus granulosus | cAMP dependent protein kinase catalytic subunit | 0.0606 | 0.4622 | 0.4622 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0039 | 0.004 | 0.004 |
Echinococcus granulosus | intersectin 2 | 0.0037 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | hypothetical protein | 0.0623 | 0.4755 | 0.475 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0279 | 0.198 | 0.198 |
Echinococcus granulosus | protein kinase c eta type | 0.0221 | 0.1509 | 0.1509 |
Echinococcus granulosus | axis inhibition protein axin | 0.0113 | 0.0635 | 0.0635 |
Schistosoma mansoni | unc-13 (munc13) | 0.0254 | 0.1778 | 0.1745 |
Schistosoma mansoni | axis inhibition protein axin | 0.0113 | 0.0635 | 0.0598 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.0039 | 0.004 | 0.004 |
Echinococcus granulosus | protein kinase c epsilon type | 0.1272 | 1 | 1 |
Echinococcus granulosus | cGMP dependent protein kinase 1 | 0.0055 | 0.0167 | 0.0167 |
Entamoeba histolytica | protein kinase, putative | 0.0279 | 0.198 | 0.3197 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0113 | 0.0635 | 0.0627 |
Loa Loa (eye worm) | hypothetical protein | 0.0606 | 0.4622 | 0.4618 |
Echinococcus granulosus | A kinase anchor protein 10 mitochondrial | 0.0113 | 0.0635 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.1778 | 0.1771 |
Echinococcus multilocularis | unc 13 (munc13) | 0.0254 | 0.1778 | 0.1778 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.319 | 0.3184 |
Echinococcus granulosus | raf serine:threonine protein kinase | 0.0222 | 0.1518 | 0.1518 |
Plasmodium vivax | cAMP-dependent protein kinase catalytic subunit, putative | 0.0606 | 0.4622 | 0.5 |
Echinococcus granulosus | enhancer of mRNA decapping protein 4 | 0.059 | 0.4489 | 0.4489 |
Loa Loa (eye worm) | PXA domain-containing protein | 0.0113 | 0.0635 | 0.0627 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.1509 | 0.1502 |
Echinococcus multilocularis | cGMP dependent protein kinase 1 | 0.0055 | 0.0167 | 0.0167 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0113 | 0.0635 | 0.0627 |
Echinococcus granulosus | Regulator of G protein signaling 20 | 0.0113 | 0.0635 | 0.0635 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0113 | 0.0635 | 0.0635 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0279 | 0.198 | 0.1948 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0279 | 0.198 | 0.198 |
Loa Loa (eye worm) | hypothetical protein | 0.0844 | 0.654 | 0.6537 |
Trypanosoma brucei | cAMP-dependent protein kinase catalytic subunit 2 | 0.0606 | 0.4622 | 1 |
Echinococcus multilocularis | G protein coupled receptor kinase 6 | 0.0494 | 0.3716 | 0.3716 |
Leishmania major | protein kinase A catalytic subunit isoform 2 | 0.0606 | 0.4622 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0292 | 0.2083 | 0.3632 |
Brugia malayi | Phorbol esters/diacylglycerol binding domain | 0.0488 | 0.367 | 0.3664 |
Toxoplasma gondii | protein kinase, cAMP-dependent, catalytic chain | 0.0606 | 0.4622 | 1 |
Schistosoma mansoni | axis inhibition protein axin | 0.0113 | 0.0635 | 0.0598 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.0039 | 0.004 | 0.004 |
Schistosoma mansoni | diacylglycerol kinase theta | 0.0221 | 0.1509 | 0.1476 |
Echinococcus granulosus | tyrosine kinase | 0.0035 | 0.0009 | 0.0009 |
Trichomonas vaginalis | serine/threonine-protein kinase sgk, putative | 0.0263 | 0.1847 | 0.3039 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.3536 | 0.3531 |
Loa Loa (eye worm) | hypothetical protein | 0.065 | 0.4975 | 0.4971 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.1509 | 0.1502 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.319 | 0.3184 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.0039 | 0.004 | 0.004 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.319 | 0.3184 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -4.774 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.746 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.636 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.561 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
IC50 (functional) | > 50 uM | Tested for cytotoxic activity against B16 mouse melanoma cells in MTT assay | ChEMBL. | No reference |
IC50 (functional) | > 50 uM | Tested for cytotoxic activity against DA-3 mouse mammary adenocarcinoma cells in MTT assay | ChEMBL. | No reference |
IC50 (functional) | > 50 uM | Tested for cytotoxic activity against HT-29 human colon adenocarcinoma cells in MTT assay | ChEMBL. | No reference |
IC50 (functional) | > 50 uM | Tested for cytotoxic activity against MCF7-WT human breast adenocarcinoma cells in MTT assay | ChEMBL. | No reference |
IC50 (functional) | > 50 uM | Tested for cytotoxic activity against B16 mouse melanoma cells in MTT assay | ChEMBL. | No reference |
IC50 (functional) | > 50 uM | Tested for cytotoxic activity against HT-29 human colon adenocarcinoma cells in MTT assay | ChEMBL. | No reference |
IC50 (functional) | > 50 uM | Tested for cytotoxic activity against MCF7-WT human breast adenocarcinoma cells in MTT assay | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.