Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | acetylcholinesterase | 0.0087 | 0.0603 | 0.0641 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.0468 | 0.3174 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0186 | 0.1451 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0023 | 0.0061 | 0.0258 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.018 | 0.1396 | 0.7216 |
Schistosoma mansoni | alpha-glucosidase | 0.0155 | 0.1183 | 0.8139 |
Echinococcus multilocularis | dna polymerase eta | 0.0023 | 0.0061 | 0.0054 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.0061 | 0.0421 |
Trypanosoma brucei | protein kinase, putative | 0.0057 | 0.0347 | 0.239 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.0468 | 0.3174 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0064 | 0.0407 | 0.2493 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.004 | 0.0204 | 0.1004 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.0061 | 0.0421 |
Mycobacterium tuberculosis | Conserved protein | 0.0186 | 0.1451 | 0.1398 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0134 | 0.1002 | 0.6885 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.004 | 0.0204 | 0.1029 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.004 | 0.0204 | 0.1029 |
Onchocerca volvulus | 0.0161 | 0.1236 | 0.4116 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.0061 | 0.0421 |
Loa Loa (eye worm) | RNA binding protein | 0.0071 | 0.0468 | 0.2381 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0061 | 0.0258 |
Brugia malayi | hypothetical protein | 0.0056 | 0.034 | 0.1711 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0186 | 0.1451 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0071 | 0.0468 | 0.2381 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0152 | 0.1155 | 0.7947 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0186 | 0.1451 | 0.3288 |
Echinococcus multilocularis | tumor protein p63 | 0.1101 | 0.9237 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0057 | 0.0347 | 0.0363 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.018 | 0.1396 | 0.7216 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0023 | 0.0061 | 0.0421 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.1451 | 0.75 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0186 | 0.1451 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0186 | 0.1451 | 0.2814 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0186 | 0.1451 | 0.1398 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0058 | 0.0356 | 0.212 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0023 | 0.0061 | 0.0344 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0023 | 0.0061 | 0.0054 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.018 | 0.1396 | 0.1501 |
Mycobacterium tuberculosis | Conserved protein | 0.0186 | 0.1451 | 0.1398 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.1451 | 0.75 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.018 | 0.1396 | 0.1501 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0058 | 0.0356 | 0.1793 |
Schistosoma mansoni | DNA polymerase eta | 0.0023 | 0.0061 | 0.0344 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.1451 | 0.75 |
Onchocerca volvulus | 0.0186 | 0.1451 | 0.5935 | |
Trichomonas vaginalis | CMGC family protein kinase | 0.0057 | 0.0347 | 0.2056 |
Brugia malayi | TAR-binding protein | 0.0071 | 0.0468 | 0.2381 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.018 | 0.1396 | 0.1501 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0025 | 0.0078 | 0.0072 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0186 | 0.1451 | 0.75 |
Loa Loa (eye worm) | hypothetical protein | 0.0184 | 0.1432 | 0.7403 |
Mycobacterium ulcerans | lipase LipD | 0.0186 | 0.1451 | 0.3288 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0064 | 0.0407 | 0.2063 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0058 | 0.0356 | 0.212 |
Plasmodium falciparum | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 0.052 | 0.4287 | 1 |
Echinococcus granulosus | dna polymerase eta | 0.0023 | 0.0061 | 0.0054 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0057 | 0.0347 | 0.2056 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0058 | 0.0356 | 0.004 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.034 | 0.1711 |
Echinococcus multilocularis | dna polymerase kappa | 0.0023 | 0.0061 | 0.0054 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.004 | 0.0204 | 0.1029 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0064 | 0.0407 | 0.082 |
Loa Loa (eye worm) | TAR-binding protein | 0.0071 | 0.0468 | 0.2381 |
Brugia malayi | MAP kinase sur-1 | 0.0057 | 0.0347 | 0.1747 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.033 | 0.1659 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.0061 | 0.0421 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0057 | 0.0347 | 0.2056 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0057 | 0.0347 | 0.239 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0023 | 0.0061 | 0.0421 |
Onchocerca volvulus | 0.0186 | 0.1451 | 0.5935 | |
Brugia malayi | beta-lactamase family protein | 0.0186 | 0.1451 | 0.75 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.004 | 0.0204 | 0.0209 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0134 | 0.1002 | 0.2227 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0023 | 0.0061 | 0.0344 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.004 | 0.0204 | 0.1029 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.004 | 0.0204 | 0.4856 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.004 | 0.0204 | 0.1029 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0058 | 0.0356 | 0.004 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0186 | 0.1451 | 0.156 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0023 | 0.0061 | 0.0421 |
Toxoplasma gondii | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative | 0.052 | 0.4287 | 1 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0057 | 0.0347 | 0.0363 |
Loa Loa (eye worm) | beta-lactamase | 0.0186 | 0.1451 | 0.75 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.1451 | 0.75 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0057 | 0.0347 | 0.2056 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0134 | 0.1002 | 0.2227 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0064 | 0.0407 | 0.0429 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0152 | 0.1155 | 0.5961 |
Mycobacterium tuberculosis | Conserved protein | 0.0186 | 0.1451 | 0.1398 |
Leishmania major | hypothetical protein, conserved | 0.0186 | 0.1451 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0057 | 0.0347 | 0.2056 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0152 | 0.1155 | 0.7947 |
Brugia malayi | beta-lactamase family protein | 0.0186 | 0.1451 | 0.75 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0057 | 0.0347 | 0.9697 |
Brugia malayi | beta-lactamase | 0.0186 | 0.1451 | 0.75 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0134 | 0.1002 | 0.1074 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0186 | 0.1451 | 1 |
Mycobacterium ulcerans | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 0.052 | 0.4287 | 1 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0186 | 0.1451 | 0.1398 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0186 | 0.1451 | 1 |
Chlamydia trachomatis | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 0.052 | 0.4287 | 0.5 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0186 | 0.1451 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0152 | 0.1155 | 0.5961 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0.0204 | 0.1029 |
Brugia malayi | N-terminal motif family protein | 0.0184 | 0.1432 | 0.7403 |
Echinococcus multilocularis | acetylcholinesterase | 0.0087 | 0.0603 | 0.0641 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0023 | 0.0061 | 0.0054 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.0468 | 0.3174 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.006 | 0.0371 | 0.1873 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0087 | 0.0603 | 0.0641 |
Plasmodium vivax | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative | 0.052 | 0.4287 | 1 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0057 | 0.0347 | 0.0349 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.1451 | 0.75 |
Echinococcus granulosus | dna polymerase kappa | 0.0023 | 0.0061 | 0.0054 |
Echinococcus granulosus | tumor protein p63 | 0.1101 | 0.9237 | 1 |
Mycobacterium leprae | PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS | 0.052 | 0.4287 | 1 |
Wolbachia endosymbiont of Brugia malayi | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 0.052 | 0.4287 | 1 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0184 | 0.1432 | 0.5778 |
Schistosoma mansoni | hypothetical protein | 0.0025 | 0.0078 | 0.0459 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0057 | 0.0347 | 0.2056 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0183 | 0.0891 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0057 | 0.0347 | 0.2056 |
Echinococcus multilocularis | tar DNA binding protein | 0.0071 | 0.0468 | 0.0495 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0152 | 0.1155 | 0.124 |
Schistosoma mansoni | alpha glucosidase | 0.004 | 0.0204 | 0.1338 |
Leishmania major | hypothetical protein, conserved | 0.0056 | 0.034 | 0.2006 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0134 | 0.1002 | 0.1074 |
Loa Loa (eye worm) | hypothetical protein | 0.0243 | 0.193 | 1 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0134 | 0.1002 | 0.6885 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0186 | 0.1451 | 0.3288 |
Brugia malayi | Carboxylesterase family protein | 0.0087 | 0.0603 | 0.3083 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0186 | 0.1451 | 1 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0171 | 0.0833 |
Toxoplasma gondii | ABC1 family protein | 0.0186 | 0.1451 | 0.3053 |
Onchocerca volvulus | Huntingtin homolog | 0.0243 | 0.193 | 1 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0134 | 0.1002 | 0.0947 |
Mycobacterium tuberculosis | Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras | 0.0125 | 0.0928 | 0.0872 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0064 | 0.0407 | 0.0429 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0161 | 0.1236 | 0.8508 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0058 | 0.0356 | 1 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0056 | 0.034 | 0.2343 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.004 | 0.0204 | 0.1029 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.033 | 0.1659 |
Mycobacterium ulcerans | hypothetical protein | 0.0186 | 0.1451 | 0.3288 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0058 | 0.0356 | 0.2452 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0087 | 0.0603 | 0.3083 |
Trypanosoma brucei | glucosidase, putative | 0.004 | 0.0204 | 0.1407 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0183 | 0.1188 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.033 | 0.1659 |
Trypanosoma brucei | unspecified product | 0.0023 | 0.0061 | 0.0421 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0058 | 0.0356 | 0.0373 |
Trichomonas vaginalis | esterase, putative | 0.0186 | 0.1451 | 1 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0058 | 0.0356 | 0.0296 |
Brugia malayi | Carboxylesterase family protein | 0.0087 | 0.0603 | 0.3083 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.0468 | 0.3174 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0186 | 0.1451 | 0.1398 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0152 | 0.1155 | 0.7947 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.0061 | 0.0421 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0186 | 0.1451 | 0.75 |
Toxoplasma gondii | exonuclease III APE | 0.0058 | 0.0356 | 0.0371 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0057 | 0.0347 | 0.2056 |
Schistosoma mansoni | alpha-glucosidase | 0.0155 | 0.1183 | 0.8139 |
Brugia malayi | RNA binding protein | 0.0071 | 0.0468 | 0.2381 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.004 | 0.0204 | 0.1029 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.033 | 0.1659 |
Echinococcus granulosus | carboxylesterase 5A | 0.0087 | 0.0603 | 0.0641 |
Loa Loa (eye worm) | hypothetical protein | 0.0243 | 0.193 | 1 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0064 | 0.0407 | 0.2751 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0057 | 0.0347 | 0.1747 |
Schistosoma mansoni | tar DNA-binding protein | 0.0071 | 0.0468 | 0.3174 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.0061 | 0.0421 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.004 | 0.0204 | 0.4856 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0056 | 0.034 | 0.0333 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0064 | 0.0407 | 0.082 |
Brugia malayi | hypothetical protein | 0.0243 | 0.193 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0057 | 0.0347 | 0.2056 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0186 | 0.1451 | 0.1398 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0134 | 0.1002 | 0.6774 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0071 | 0.0468 | 0.2381 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0152 | 0.1155 | 0.124 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.0061 | 0.0421 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0152 | 0.1155 | 0.124 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.0061 | 0.0421 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0186 | 0.1451 | 1 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0058 | 0.0356 | 0.0697 |
Loa Loa (eye worm) | carboxylesterase | 0.0087 | 0.0603 | 0.3083 |
Schistosoma mansoni | ap endonuclease | 0.0058 | 0.0356 | 0.2391 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.004 | 0.0204 | 0.1029 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0186 | 0.1451 | 0.1398 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 0.1325 | 0.9124 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0186 | 0.1451 | 0.156 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.0183 | 0.0891 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.0061 | 0.0421 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0603 | 0.3083 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.004 | 0.0204 | 0.1004 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0023 | 0.0061 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0186 | 0.1451 | 0.75 |
Treponema pallidum | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 0.052 | 0.4287 | 1 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0025 | 0.0078 | 0.0072 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0603 | 0.3083 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0023 | 0.0061 | 0.0421 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0058 | 0.0356 | 0.0373 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0023 | 0.0061 | 0.0258 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0056 | 0.034 | 0.2006 |
Onchocerca volvulus | 0.0186 | 0.1451 | 0.5935 | |
Echinococcus granulosus | acetylcholinesterase | 0.0087 | 0.0603 | 0.0641 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0152 | 0.1155 | 0.124 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0058 | 0.0356 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0057 | 0.0347 | 0.0363 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0134 | 0.1002 | 0.2227 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.004 | 0.0204 | 0.0209 |
Echinococcus granulosus | geminin | 0.0172 | 0.1325 | 0.1423 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0186 | 0.1451 | 0.1398 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0058 | 0.0356 | 0.212 |
Schistosoma mansoni | hypothetical protein | 0.0172 | 0.1325 | 0.9124 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0064 | 0.0407 | 0.0348 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0058 | 0.0356 | 0.212 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0023 | 0.0061 | 0.0421 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0058 | 0.0356 | 0.1793 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0087 | 0.0603 | 0.411 |
Leishmania major | alpha glucosidase II subunit, putative | 0.004 | 0.0204 | 0.1029 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.1236 | 0.6381 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0134 | 0.1002 | 0.1955 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0056 | 0.034 | 0.2006 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0057 | 0.0347 | 0.2056 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0186 | 0.1451 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0058 | 0.0356 | 0.212 |
Onchocerca volvulus | Huntingtin homolog | 0.0243 | 0.193 | 1 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0186 | 0.1451 | 0.1398 |
Echinococcus granulosus | tar DNA binding protein | 0.0071 | 0.0468 | 0.0495 |
Echinococcus granulosus | acetylcholinesterase | 0.0087 | 0.0603 | 0.0641 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.004 | 0.0204 | 0.1029 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.004 | 0.0204 | 0.1029 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0186 | 0.1451 | 1 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0057 | 0.0347 | 0.0363 |
Schistosoma mansoni | ap endonuclease | 0.0058 | 0.0356 | 0.2391 |
Mycobacterium ulcerans | beta-lactamase | 0.0186 | 0.1451 | 0.3288 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0057 | 0.0347 | 0.2329 |
Echinococcus multilocularis | geminin | 0.0172 | 0.1325 | 0.1423 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Log IC50 (binding) | = 7.19 | Inhibitory concentration against DOXP reductoisomerase | ChEMBL. | 15887963 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.