Detailed information for compound 335773

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 192.087 | Formula: C5H7NO5P---
  • H donors: 0 H acceptors: 5 LogP: -2.68 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)N(C/C=C/P(=O)([O-])[O-])[O-]
  • InChi: 1S/C5H9NO5P/c1-5(7)6(8)3-2-4-12(9,10)11/h2,4H,3H2,1H3,(H2,9,10,11)/q-1/p-2/b4-2+
  • InChiKey: KCFDITWFJOQFJV-DUXPYHPUSA-L  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni alpha-glucosidase 0.0155 0.1183 0.8139
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0347 0.2056
Mycobacterium tuberculosis Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras 0.0125 0.0928 0.0872
Leishmania major hypothetical protein, conserved 0.0056 0.034 0.2006
Trypanosoma brucei hypothetical protein, conserved 0.0186 0.1451 1
Trichomonas vaginalis maltase-glucoamylase, putative 0.004 0.0204 0.1029
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0186 0.1451 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0058 0.0356 0.0296
Onchocerca volvulus 0.0186 0.1451 0.5935
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0134 0.1002 0.1074
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0058 0.0356 0.0373
Mycobacterium ulcerans beta-lactamase 0.0186 0.1451 0.3288
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0152 0.1155 0.7947
Plasmodium vivax 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.052 0.4287 1
Loa Loa (eye worm) hypothetical protein 0.0186 0.1451 0.75
Trichomonas vaginalis esterase, putative 0.0186 0.1451 1
Loa Loa (eye worm) carboxylesterase 0.0087 0.0603 0.3083
Loa Loa (eye worm) hypothetical protein 0.0186 0.1451 0.75
Toxoplasma gondii exonuclease III APE 0.0058 0.0356 0.0371
Schistosoma mansoni aldehyde dehydrogenase 0.0134 0.1002 0.6885
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0058 0.0356 0.212
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0347 0.2056
Schistosoma mansoni hypothetical protein 0.0025 0.0078 0.0459
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0468 0.3174
Echinococcus granulosus lysosomal alpha glucosidase 0.018 0.1396 0.1501
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0204 0.1029
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0061 0.0344
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.033 0.1659
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0204 0.1029
Mycobacterium tuberculosis Probable lipase LipE 0.0186 0.1451 0.1398
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0061 0.0421
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0061 0.0421
Trypanosoma brucei DNA polymerase eta, putative 0.0023 0.0061 0.0421
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0058 0.0356 0.0373
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0055 0.033 0.1659
Echinococcus granulosus tar DNA binding protein 0.0071 0.0468 0.0495
Brugia malayi hypothetical protein 0.0036 0.0171 0.0833
Trypanosoma brucei PAB1-binding protein , putative 0.0056 0.034 0.2343
Echinococcus multilocularis mitogen activated protein kinase 0.0057 0.0347 0.0363
Loa Loa (eye worm) hypothetical protein 0.0186 0.1451 0.75
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0061 0.0344
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0057 0.0347 0.0349
Trypanosoma brucei unspecified product 0.0023 0.0061 0.0421
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0152 0.1155 0.5961
Brugia malayi hypothetical protein 0.0056 0.034 0.1711
Echinococcus multilocularis lysosomal alpha glucosidase 0.018 0.1396 0.1501
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0025 0.0078 0.0072
Echinococcus granulosus dna polymerase eta 0.0023 0.0061 0.0054
Brugia malayi exodeoxyribonuclease III family protein 0.0058 0.0356 0.1793
Mycobacterium ulcerans aldehyde dehydrogenase 0.0134 0.1002 0.2227
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0356 0.004
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0058 0.0356 0.0697
Plasmodium vivax hypothetical protein, conserved 0.0186 0.1451 0.2814
Brugia malayi N-terminal motif family protein 0.0184 0.1432 0.7403
Echinococcus granulosus mitogen activated protein kinase 0.0057 0.0347 0.0363
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0025 0.0078 0.0072
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0204 0.1029
Schistosoma mansoni hypothetical protein 0.0172 0.1325 0.9124
Mycobacterium tuberculosis Probable lipase LipD 0.0186 0.1451 0.1398
Brugia malayi Glycosyl hydrolases family 31 protein 0.018 0.1396 0.7216
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0058 0.0356 0.212
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0186 0.1451 0.75
Toxoplasma gondii ABC1 family protein 0.0186 0.1451 0.3053
Echinococcus multilocularis geminin 0.0172 0.1325 0.1423
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.018 0.1396 0.7216
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0183 0.0891
Trypanosoma cruzi hypothetical protein, conserved 0.0186 0.1451 1
Echinococcus granulosus acetylcholinesterase 0.0087 0.0603 0.0641
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0061 0.0421
Trichomonas vaginalis sucrase-isomaltase, putative 0.004 0.0204 0.1029
Loa Loa (eye worm) acetylcholinesterase 1 0.0087 0.0603 0.3083
Schistosoma mansoni hypothetical protein 0.0037 0.0183 0.1188
Brugia malayi beta-lactamase family protein 0.0186 0.1451 0.75
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0087 0.0603 0.411
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0204 0.4856
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0058 0.0356 0.1793
Schistosoma mansoni serine/threonine protein kinase 0.0057 0.0347 0.2329
Leishmania major hypothetical protein, conserved 0.0186 0.1451 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0064 0.0407 0.2493
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0061 0.0421
Loa Loa (eye worm) hypothetical protein 0.0087 0.0603 0.3083
Loa Loa (eye worm) hypothetical protein 0.0186 0.1451 0.75
Echinococcus granulosus beta LACTamase domain containing family member 0.0186 0.1451 0.156
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0058 0.0356 0.004
Loa Loa (eye worm) hypothetical protein 0.0186 0.1451 0.75
Trypanosoma cruzi PAB1-binding protein , putative 0.0056 0.034 0.2006
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0057 0.0347 0.2056
Mycobacterium leprae PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS 0.052 0.4287 1
Mycobacterium tuberculosis Probable hydrolase 0.0186 0.1451 0.1398
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0152 0.1155 0.5961
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0061 0.0421
Mycobacterium tuberculosis Conserved protein 0.0186 0.1451 0.1398
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0061 0.0258
Plasmodium falciparum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.4287 1
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0061 0.0054
Wolbachia endosymbiont of Brugia malayi 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.4287 1
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0061 0.0421
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0186 0.1451 0.1398
Echinococcus multilocularis tumor protein p63 0.1101 0.9237 1
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0061 0.0421
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0057 0.0347 0.2056
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0064 0.0407 0.0348
Loa Loa (eye worm) hypothetical protein 0.0161 0.1236 0.6381
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0356 0.212
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0064 0.0407 0.2751
Leishmania major alpha glucosidase II subunit, putative 0.004 0.0204 0.1029
Toxoplasma gondii 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.052 0.4287 1
Brugia malayi TAR-binding protein 0.0071 0.0468 0.2381
Echinococcus multilocularis neutral alpha glucosidase AB 0.004 0.0204 0.0209
Schistosoma mansoni ap endonuclease 0.0058 0.0356 0.2391
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0186 0.1451 0.3288
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0061 0.0258
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0061 0.0421
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0058 0.0356 0.212
Loa Loa (eye worm) RNA binding protein 0.0071 0.0468 0.2381
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0057 0.0347 0.2056
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.004 0.0204 0.1004
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0186 0.1451 1
Brugia malayi RNA recognition motif domain containing protein 0.0071 0.0468 0.2381
Echinococcus granulosus acetylcholinesterase 0.0087 0.0603 0.0641
Trypanosoma cruzi hypothetical protein, conserved 0.0186 0.1451 1
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0407 0.0429
Loa Loa (eye worm) hypothetical protein 0.0243 0.193 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0186 0.1451 1
Mycobacterium tuberculosis Probable esterase LipL 0.0186 0.1451 0.1398
Mycobacterium ulcerans hypothetical protein 0.0186 0.1451 0.3288
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0058 0.0356 0.2452
Echinococcus multilocularis lysosomal alpha glucosidase 0.018 0.1396 0.1501
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0061 0.0421
Loa Loa (eye worm) hypothetical protein 0.0087 0.0603 0.3083
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0184 0.1432 0.5778
Echinococcus granulosus mitogen activated protein kinase 3 0.0057 0.0347 0.0363
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0407 0.082
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0058 0.0356 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0134 0.1002 0.1074
Brugia malayi Carboxylesterase family protein 0.0087 0.0603 0.3083
Toxoplasma gondii aldehyde dehydrogenase 0.0134 0.1002 0.1955
Loa Loa (eye worm) hypothetical protein 0.0184 0.1432 0.7403
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0347 0.2056
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0347 0.2056
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0057 0.0347 0.1747
Trichomonas vaginalis D-aminoacylase, putative 0.0186 0.1451 1
Schistosoma mansoni aldehyde dehydrogenase 0.0134 0.1002 0.6885
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0134 0.1002 0.0947
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0204 0.1029
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0204 0.1029
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0407 0.0429
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0057 0.0347 0.2056
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0061 0.0421
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0204 0.1029
Mycobacterium ulcerans aldehyde dehydrogenase 0.0134 0.1002 0.2227
Schistosoma mansoni DNA polymerase eta 0.0023 0.0061 0.0344
Chlamydia trachomatis 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.4287 0.5
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0152 0.1155 0.124
Toxoplasma gondii LsmAD domain-containing protein 0.0056 0.034 0.0333
Loa Loa (eye worm) TAR-binding protein 0.0071 0.0468 0.2381
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0204 0.1029
Brugia malayi beta-lactamase family protein 0.0186 0.1451 0.75
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0061 0.0258
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0134 0.1002 0.6774
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0057 0.0347 0.239
Echinococcus multilocularis mitogen activated protein kinase 3 0.0057 0.0347 0.0363
Mycobacterium ulcerans esterase/lipase LipP 0.0186 0.1451 0.3288
Trichomonas vaginalis ap endonuclease, putative 0.0058 0.0356 0.212
Brugia malayi hypothetical protein 0.0243 0.193 1
Mycobacterium ulcerans 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.4287 1
Trichomonas vaginalis alpha-glucosidase, putative 0.004 0.0204 0.1029
Trichomonas vaginalis D-aminoacylase, putative 0.0186 0.1451 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0061 0.0421
Loa Loa (eye worm) hypothetical protein 0.0037 0.0183 0.0891
Trichomonas vaginalis penicillin-binding protein, putative 0.0186 0.1451 1
Mycobacterium tuberculosis Conserved protein 0.0186 0.1451 0.1398
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0061 0.0054
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0061 0.0421
Onchocerca volvulus 0.0186 0.1451 0.5935
Echinococcus multilocularis carboxylesterase 5A 0.0087 0.0603 0.0641
Onchocerca volvulus Huntingtin homolog 0.0243 0.193 1
Schistosoma mansoni ap endonuclease 0.0058 0.0356 0.2391
Mycobacterium ulcerans lipase LipD 0.0186 0.1451 0.3288
Echinococcus multilocularis beta LACTamase domain containing family member 0.0186 0.1451 0.156
Echinococcus granulosus neutral alpha glucosidase AB 0.004 0.0204 0.0209
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0071 0.0468 0.2381
Trypanosoma brucei protein kinase, putative 0.0057 0.0347 0.239
Loa Loa (eye worm) hypothetical protein 0.0055 0.033 0.1659
Loa Loa (eye worm) beta-lactamase 0.0186 0.1451 0.75
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.033 0.1659
Brugia malayi Carboxylesterase family protein 0.0087 0.0603 0.3083
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0057 0.0347 0.2056
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.004 0.0204 0.1029
Echinococcus granulosus carboxylesterase 5A 0.0087 0.0603 0.0641
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.004 0.0204 0.4856
Giardia lamblia Kinase, CMGC MAPK 0.0057 0.0347 0.9697
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0152 0.1155 0.124
Trichomonas vaginalis CMGC family protein kinase 0.0057 0.0347 0.2056
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0186 0.1451 0.75
Brugia malayi RNA binding protein 0.0071 0.0468 0.2381
Echinococcus multilocularis acetylcholinesterase 0.0087 0.0603 0.0641
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0407 0.082
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.006 0.0371 0.1873
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0468 0.3174
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0186 0.1451 0.1398
Loa Loa (eye worm) hypothetical protein 0.0186 0.1451 0.75
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0064 0.0407 0.2063
Echinococcus granulosus tumor protein p63 0.1101 0.9237 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0152 0.1155 0.124
Echinococcus multilocularis acetylcholinesterase 0.0087 0.0603 0.0641
Schistosoma mansoni cellular tumor antigen P53 0.0161 0.1236 0.8508
Trichomonas vaginalis D-aminoacylase, putative 0.0186 0.1451 1
Echinococcus granulosus geminin 0.0172 0.1325 0.1423
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0061 0.0421
Echinococcus multilocularis tar DNA binding protein 0.0071 0.0468 0.0495
Trypanosoma brucei glucosidase, putative 0.004 0.0204 0.1407
Brugia malayi Glycosyl hydrolases family 31 protein 0.004 0.0204 0.1004
Schistosoma mansoni alpha-glucosidase 0.0155 0.1183 0.8139
Schistosoma mansoni hypothetical protein 0.0172 0.1325 0.9124
Onchocerca volvulus 0.0161 0.1236 0.4116
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0468 0.3174
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0186 0.1451 0.1398
Brugia malayi beta-lactamase 0.0186 0.1451 0.75
Loa Loa (eye worm) hypothetical protein 0.0243 0.193 1
Loa Loa (eye worm) hypothetical protein 0.0056 0.034 0.1711
Echinococcus granulosus dna polymerase kappa 0.0023 0.0061 0.0054
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0058 0.0356 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0152 0.1155 0.7947
Brugia malayi MAP kinase sur-1 0.0057 0.0347 0.1747
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0061 0.0054
Trypanosoma cruzi PAB1-binding protein , putative 0.0056 0.034 0.2006
Onchocerca volvulus Huntingtin homolog 0.0243 0.193 1
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0468 0.3174
Onchocerca volvulus 0.0186 0.1451 0.5935
Loa Loa (eye worm) hypothetical protein 0.0023 0.0061 0.0258
Mycobacterium ulcerans aldehyde dehydrogenase 0.0134 0.1002 0.2227
Schistosoma mansoni tar DNA-binding protein 0.0071 0.0468 0.3174
Schistosoma mansoni alpha glucosidase 0.004 0.0204 0.1338
Mycobacterium tuberculosis Conserved protein 0.0186 0.1451 0.1398
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0152 0.1155 0.7947
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0152 0.1155 0.124
Treponema pallidum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.052 0.4287 1
Echinococcus multilocularis dna polymerase eta 0.0023 0.0061 0.0054

Activities

Activity type Activity value Assay description Source Reference
Log IC50 (binding) = 7.19 Inhibitory concentration against DOXP reductoisomerase ChEMBL. 15887963

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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