Detailed information for compound 425063

Basic information

Technical information
  • TDR Targets ID: 425063
  • Name: 1-hydroxy-N-(4-hydroxyphenyl)naphthalene-2-ca rboxamide
  • MW: 279.29 | Formula: C17H13NO3
  • H donors: 3 H acceptors: 3 LogP: 3.85 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc(cc1)NC(=O)c1ccc2c(c1O)cccc2
  • InChi: 1S/C17H13NO3/c19-13-8-6-12(7-9-13)18-17(21)15-10-5-11-3-1-2-4-14(11)16(15)20/h1-10,19-20H,(H,18,21)
  • InChiKey: UVPVMSQHZQXBCO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 1-hydroxy-N-(4-hydroxyphenyl)-2-naphthalenecarboxamide
  • 1-hydroxy-N-(4-hydroxyphenyl)-2-naphthamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis allatostatin A receptor 0.024 0.0315 0.0568
Loa Loa (eye worm) acetyltransferase 0.0167 0.0203 0.0203
Plasmodium vivax endoplasmin, putative 0.0146 0.0171 0.5906
Schistosoma mansoni amine GPCR 0.024 0.0315 0.0715
Trichomonas vaginalis tubulin, putative 0.0214 0.0275 0.7996
Brugia malayi hypothetical protein 0.024 0.0315 0.0315
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.024 0.0315 0.0715
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.024 0.0315 0.0315
Schistosoma mansoni rhodopsin-like orphan GPCR 0.024 0.0315 0.0715
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0207 0.6033
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0462 0.0656 0.0656
Brugia malayi hypothetical protein 0.024 0.0315 0.0315
Brugia malayi Melatonin receptor type 1A 0.024 0.0315 0.0315
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0132 0.015 0.5
Echinococcus granulosus alpha 1A adrenergic receptor 0.024 0.0315 0.0568
Echinococcus multilocularis beta tubulin 0.0214 0.0275 0.0496
Onchocerca volvulus 0.024 0.0315 0.0513
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Trypanosoma cruzi beta tubulin, putative 0.0214 0.0275 1
Trichomonas vaginalis DNA polymerase eta, putative 0.0044 0.0015 0.0446
Loa Loa (eye worm) BEN-1 protein 0.0214 0.0275 0.0275
Trypanosoma brucei heat shock protein 90, putative 0.0146 0.0171 0.6238
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0049 0.1524
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0049 0.0087
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0554 0.0796 0.2813
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Trichomonas vaginalis tubulin beta chain, putative 0.0214 0.0275 0.7996
Loa Loa (eye worm) tubulin beta-4 chain 0.0214 0.0275 0.0275
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Trypanosoma cruzi heat shock protein 85, putative 0.0146 0.0171 0.6238
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Trypanosoma brucei beta tubulin 0.0214 0.0275 1
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Echinococcus granulosus dna polymerase kappa 0.0044 0.0015 0.0028
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.024 0.0315 0.0568
Schistosoma mansoni hypothetical protein 0.1361 0.2034 0.4619
Echinococcus multilocularis Tubulin beta 2C chain 0.0214 0.0275 0.0496
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus multilocularis neuropeptides capa receptor 0.024 0.0315 0.0568
Brugia malayi Serotonin/octopamine receptor family protein 7 0.024 0.0315 0.0315
Schistosoma mansoni myosin xvIII 0.024 0.0315 0.0715
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.2809 0.4254 0.7673
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.024 0.0315 0.0568
Toxoplasma gondii heat shock protein HSP90 0.0146 0.0171 0.0283
Echinococcus granulosus G protein coupled receptor 139 0.024 0.0315 0.0568
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0527 0.0756 0.1363
Echinococcus multilocularis g protein coupled receptor 0.024 0.0315 0.0568
Schistosoma mansoni heat shock protein 0.0146 0.0171 0.0389
Echinococcus multilocularis g-protein coupled receptor 0.024 0.0315 0.0568
Schistosoma mansoni rhodopsin-like orphan GPCR 0.024 0.0315 0.0715
Entamoeba histolytica heat shock protein 90, putative 0.0146 0.0171 0.6238
Echinococcus granulosus heat shock protein 0.0146 0.0171 0.0309
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0224 0.0291 0.0525
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Giardia lamblia Beta tubulin 0.0214 0.0275 1
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0167 0.0203 0.046
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0103 0.0105 0.0105
Brugia malayi ORL1-like opioid receptor 0.024 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0224 0.0291 0.0525
Onchocerca volvulus 0.024 0.0315 0.0513
Onchocerca volvulus 0.024 0.0315 0.0513
Echinococcus multilocularis dna polymerase kappa 0.0044 0.0015 0.0028
Onchocerca volvulus 0.024 0.0315 0.0513
Echinococcus multilocularis neuropeptide FF receptor 2 0.024 0.0315 0.0568
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Echinococcus granulosus rhodopsin orphan GPCR 0.024 0.0315 0.0568
Trypanosoma cruzi heat shock protein 90, putative 0.0132 0.015 0.5467
Schistosoma mansoni endoplasmin 0.0146 0.0171 0.0389
Echinococcus multilocularis dual specificity mitogen activated protein 0.0072 0.0057 0.0103
Schistosoma mansoni opsin-like receptor 0.024 0.0315 0.0715
Onchocerca volvulus 0.024 0.0315 0.0513
Echinococcus granulosus neuropeptide FF receptor 2 0.024 0.0315 0.0568
Brugia malayi follicle stimulating hormone receptor 0.0462 0.0656 0.0656
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0072 0.0057 0.2088
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Echinococcus granulosus dual specificity mitogen activated protein 0.0072 0.0057 0.0103
Schistosoma mansoni tubulin subunit beta 0.0214 0.0275 0.0624
Brugia malayi Dopamine receptor protein 1 0.024 0.0315 0.0315
Echinococcus granulosus fmrfamide receptor 0.024 0.0315 0.0568
Echinococcus granulosus heat shock protein 90 0.0132 0.015 0.0271
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Schistosoma mansoni biogenic amine receptor 0.024 0.0315 0.0715
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.024 0.0315 0.0568
Echinococcus multilocularis neuropeptide receptor 0.126 0.1879 0.3389
Echinococcus multilocularis integrin beta 2 0.0501 0.0715 0.1289
Echinococcus granulosus rhodopsin orphan GPCR 0.024 0.0315 0.0568
Echinococcus granulosus beta tubulin 0.0214 0.0275 0.0496
Brugia malayi Calcitonin receptor-like protein seb-1 0.4267 0.6489 0.6489
Echinococcus multilocularis heat shock protein 0.0146 0.0171 0.0309
Trypanosoma cruzi heat shock protein 85, putative 0.0146 0.0171 0.6238
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus multilocularis rhodopsin orphan GPCR 0.024 0.0315 0.0568
Brugia malayi hypothetical protein 0.024 0.0315 0.0315
Schistosoma mansoni growth hormone secretagogue receptor 0.024 0.0315 0.0715
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0006 0.0011
Giardia lamblia Heat shock protein HSP 90-alpha 0.0146 0.0171 0.6238
Echinococcus granulosus beta tubulin 0.0214 0.0275 0.0496
Schistosoma mansoni rhodopsin-like orphan GPCR 0.024 0.0315 0.0715
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus granulosus tubulin subunit beta 0.0214 0.0275 0.0496
Brugia malayi hypothetical protein 0.024 0.0315 0.0315
Echinococcus multilocularis Tubulin beta 2C chain 0.0214 0.0275 0.0496
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Trichomonas vaginalis heat shock protein, putative 0.0132 0.015 0.4371
Onchocerca volvulus Neuropeptide F receptor homolog 0.024 0.0315 0.0513
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.024 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0006 0.0011
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.1361 0.2034 0.2034
Schistosoma mansoni hypothetical protein 0.0224 0.0291 0.0661
Schistosoma mansoni hypothetical protein 0.024 0.0315 0.0715
Entamoeba histolytica heat shock protein 90, putative 0.0146 0.0171 0.6238
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Trichomonas vaginalis heat shock protein, putative 0.0132 0.015 0.4371
Giardia lamblia Kinase, STE STE20 0.0072 0.0057 0.2088
Echinococcus multilocularis tubulin subunit beta 0.0214 0.0275 0.0496
Toxoplasma gondii heat shock protein 90, putative 0.0146 0.0171 0.0283
Echinococcus granulosus 7tm_1 domain containing protein 0.024 0.0315 0.0568
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.024 0.0315 0.0715
Toxoplasma gondii beta tubulin 0.0214 0.0275 0.0454
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0221 0.644
Echinococcus multilocularis g protein coupled receptor 0.024 0.0315 0.0568
Loa Loa (eye worm) tubulin beta-2A chain 0.0214 0.0275 0.0275
Schistosoma mansoni rhodopsin-like orphan GPCR 0.024 0.0315 0.0715
Entamoeba histolytica tubulin family protein 0.0214 0.0275 1
Giardia lamblia Heat shock protein HSP 90-alpha 0.0132 0.015 0.5467
Trichomonas vaginalis STE family protein kinase 0.0072 0.0057 0.1669
Echinococcus granulosus Tubulin beta 2C chain 0.0214 0.0275 0.0496
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Plasmodium falciparum tubulin beta chain 0.0214 0.0275 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.024 0.0315 0.0715
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.365 0.5544 1
Loa Loa (eye worm) BEN-1 protein 0.0214 0.0275 0.0275
Echinococcus granulosus histone acetyltransferase KAT2B 0.0162 0.0195 0.0352
Echinococcus multilocularis G protein coupled receptor 139 0.126 0.1879 0.3389
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.024 0.0315 0.0568
Plasmodium falciparum heat shock protein 90 0.0146 0.0171 0.6238
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Schistosoma mansoni biogenic amine receptor 0.024 0.0315 0.0715
Echinococcus multilocularis adenylate cyclase type IX 0.0194 0.0245 0.0442
Schistosoma mansoni integrin beta subunit 0.0398 0.0557 0.1266
Plasmodium vivax heat shock protein 86, putative 0.0146 0.0171 0.5906
Giardia lamblia Beta tubulin 0.0214 0.0275 1
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0072 0.0057 0.2088
Brugia malayi putative neuropeptide receptor NPR1 0.024 0.0315 0.0315
Brugia malayi hypothetical protein 0.024 0.0315 0.0315
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Brugia malayi hypothetical protein 0.024 0.0315 0.0315
Loa Loa (eye worm) tubulin beta-1 chain 0.0214 0.0275 0.0275
Onchocerca volvulus 0.024 0.0315 0.0513
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Plasmodium vivax tubulin beta chain, putative 0.0214 0.0275 1
Brugia malayi RE15519p 0.024 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0207 0.6033
Schistosoma mansoni hypothetical protein 0.2906 0.4403 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.024 0.0315 0.0715
Echinococcus granulosus Tubulin beta 2C chain 0.0214 0.0275 0.0496
Onchocerca volvulus 0.024 0.0315 0.0513
Echinococcus multilocularis rhodopsin orphan GPCR 0.024 0.0315 0.0568
Schistosoma mansoni opsin-like receptor 0.024 0.0315 0.0715
Loa Loa (eye worm) hypothetical protein 0.2906 0.4403 0.4403
Toxoplasma gondii beta-1 tubulin, putative 0.0214 0.0275 0.0454
Schistosoma mansoni histamine h1 receptor 0.024 0.0315 0.0715
Echinococcus granulosus biogenic amine 5HT receptor 0.024 0.0315 0.0568
Trypanosoma brucei beta tubulin 0.0214 0.0275 1
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus multilocularis g protein coupled receptor 0.024 0.0315 0.0568
Loa Loa (eye worm) beta-tubulin 0.0214 0.0275 0.0275
Brugia malayi Serotonin receptor 0.024 0.0315 0.0315
Echinococcus multilocularis endoplasmin 0.0132 0.015 0.0271
Loa Loa (eye worm) hypothetical protein 0.0554 0.0796 0.0796
Brugia malayi G protein-coupled receptor 0.024 0.0315 0.0315
Entamoeba histolytica acetyltransferase, GNAT family 0.0045 0.0016 0.0582
Onchocerca volvulus 0.024 0.0315 0.0513
Brugia malayi hypothetical protein 0.0103 0.0105 0.0105
Echinococcus granulosus g protein coupled receptor 0.024 0.0315 0.0568
Trichomonas vaginalis heat shock protein, putative 0.0132 0.015 0.4371
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.024 0.0315 0.0715
Schistosoma mansoni neuropeptide receptor 0.024 0.0315 0.0715
Brugia malayi larval opioid receptor 0.024 0.0315 0.0315
Echinococcus granulosus neuropeptide receptor A26 0.024 0.0315 0.0568
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0049 0.0022 0.0037
Schistosoma mansoni amine GPCR 0.024 0.0315 0.0715
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Echinococcus multilocularis fmrfamide receptor 0.024 0.0315 0.0568
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Echinococcus granulosus neuropeptide Y receptor 0.024 0.0315 0.0568
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Brugia malayi Serotonin receptor 0.024 0.0315 0.0315
Onchocerca volvulus 0.024 0.0315 0.0513
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.024 0.0315 0.0715
Brugia malayi heat shock protein 90 0.0146 0.0171 0.0171
Schistosoma mansoni hypothetical protein 0.1361 0.2034 0.4619
Plasmodium falciparum endoplasmin, putative 0.0042 0.0011 0.0398
Brugia malayi putative neuropeptide receptor 0.024 0.0315 0.0315
Loa Loa (eye worm) neuropeptide F receptor 0.024 0.0315 0.0315
Echinococcus granulosus neuropeptide receptor 0.126 0.1879 0.3389
Echinococcus multilocularis Tubulin beta 2C chain 0.0214 0.0275 0.0496
Trypanosoma cruzi heat shock protein 85, putative 0.0132 0.015 0.5467
Echinococcus multilocularis neuropeptide Y receptor 0.024 0.0315 0.0568
Echinococcus multilocularis rhodopsin orphan GPCR 0.024 0.0315 0.0568
Schistosoma mansoni hypothetical protein 0.1361 0.2034 0.4619
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0049 0.0049
Echinococcus multilocularis serotonin receptor 0.024 0.0315 0.0568
Trichomonas vaginalis glucosylceramidase, putative 0.0179 0.0221 0.644
Trypanosoma cruzi heat shock protein 90, putative 0.0118 0.0129 0.4687
Echinococcus multilocularis G-protein coupled receptor, putative 0.024 0.0315 0.0568
Schistosoma mansoni rhodopsin-like orphan GPCR 0.024 0.0315 0.0715
Echinococcus multilocularis Tubulin beta 2C chain 0.0214 0.0275 0.0496
Brugia malayi neuropeptide F receptor 0.024 0.0315 0.0315
Echinococcus multilocularis biogenic amine (5HT) receptor 0.024 0.0315 0.0568
Loa Loa (eye worm) hypothetical protein 0.6556 1 1
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Schistosoma mansoni rhodopsin-like orphan GPCR 0.024 0.0315 0.0715
Loa Loa (eye worm) pigment dispersing factor receptor c 0.4267 0.6489 0.6489
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0049 0.1765
Schistosoma mansoni hypothetical protein 0.024 0.0315 0.0715
Trypanosoma brucei Heat shock protein 83, putative 0.0146 0.0171 0.6238
Onchocerca volvulus 0.024 0.0315 0.0513
Giardia lamblia Beta tubulin 0.0214 0.0275 1
Brugia malayi G-protein coupled receptor 0.024 0.0315 0.0315
Echinococcus multilocularis rhodopsin orphan GPCR 0.024 0.0315 0.0568
Echinococcus granulosus hypothetical protein 0.024 0.0315 0.0568
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus multilocularis adenylate cyclase 9 0.0554 0.0796 0.1436
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.1361 0.2034 0.3668
Echinococcus multilocularis heat shock protein 90 0.0132 0.015 0.0271
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0049 0.0087
Brugia malayi Endoplasmin precursor 0.0146 0.0171 0.0171
Echinococcus granulosus rhodopsin orphan GPCR 0.024 0.0315 0.0568
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.024 0.0315 0.0513
Echinococcus granulosus g protein coupled receptor 0.024 0.0315 0.0568
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.024 0.0315 0.0715
Loa Loa (eye worm) neuropeptide F receptor 0.024 0.0315 0.0315
Brugia malayi hypothetical protein 0.024 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Brugia malayi Caveolin-1 0.053 0.0759 0.0759
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.024 0.0315 0.0315
Echinococcus granulosus rhodopsin orphan GPCR 0.024 0.0315 0.0568
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus granulosus integrin beta 2 0.0501 0.0715 0.1289
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus granulosus g protein coupled receptor 0.024 0.0315 0.0568
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0132 0.015 0.5
Echinococcus granulosus neuropeptides capa receptor 0.024 0.0315 0.0568
Schistosoma mansoni tubulin subunit beta 0.0214 0.0275 0.0624
Brugia malayi Dopamine receptor 0.024 0.0315 0.0315
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Brugia malayi G-protein coupled receptor 0.024 0.0315 0.0315
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0004 0.0159
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0049 0.011
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Schistosoma mansoni rhodopsin-like orphan GPCR 0.024 0.0315 0.0715
Echinococcus multilocularis Tubulin beta 2C chain 0.0214 0.0275 0.0496
Trichomonas vaginalis STE family protein kinase 0.0072 0.0057 0.1669
Loa Loa (eye worm) G-protein coupled receptor 0.024 0.0315 0.0315
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Trypanosoma brucei unspecified product 0.0037 0.0004 0.0159
Schistosoma mansoni biogenic amine (5HT) receptor 0.024 0.0315 0.0715
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0132 0.015 0.4718
Brugia malayi Dopamine receptor protein 2 0.024 0.0315 0.0315
Echinococcus granulosus thyrotropin releasing hormone receptor 0.024 0.0315 0.0568
Echinococcus granulosus Tubulin beta 2C chain 0.0214 0.0275 0.0496
Schistosoma mansoni amine GPCR 0.024 0.0315 0.0715
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.024 0.0315 0.0568
Echinococcus granulosus tachykinin peptides receptor 99D 0.0527 0.0756 0.1363
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0207 0.6033
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.024 0.0315 0.0568
Echinococcus granulosus tubulin beta 1 chain 0.0214 0.0275 0.0496
Toxoplasma gondii 1,3-beta-glucan synthase component protein 0.3979 0.6049 1
Schistosoma mansoni tubulin subunit beta 0.0214 0.0275 0.0624
Plasmodium falciparum histone acetyltransferase GCN5 0.0045 0.0016 0.0582
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Schistosoma mansoni hypothetical protein 0.0224 0.0291 0.0661
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.0015 0.0558
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.024 0.0315 0.0715
Echinococcus granulosus serotonin receptor 0.024 0.0315 0.0568
Echinococcus multilocularis fmrfamide receptor 0.024 0.0315 0.0568
Brugia malayi acetyltransferase, GNAT family protein 0.0167 0.0203 0.0203
Echinococcus multilocularis rhodopsin orphan GPCR 0.024 0.0315 0.0568
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Echinococcus granulosus Tubulin beta 2C chain 0.0214 0.0275 0.0496
Schistosoma mansoni peptide (allatostatin)-like receptor 0.024 0.0315 0.0715
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0207 0.6033
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Echinococcus multilocularis heat shock protein 90 0.0146 0.0171 0.0309
Echinococcus granulosus tubulin beta 4A class IVa 0.0214 0.0275 0.0496
Brugia malayi hypothetical protein 0.024 0.0315 0.0315
Onchocerca volvulus 0.024 0.0315 0.0513
Loa Loa (eye worm) hypothetical protein 0.1361 0.2034 0.2034
Trichomonas vaginalis tubulin alpha chain, putative 0.0214 0.0275 0.7996
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0207 0.6033
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0259 0.0344 0.0344
Loa Loa (eye worm) hypothetical protein 0.1511 0.2263 0.2263
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0214 0.0275 0.0496
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.024 0.0315 0.0568
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.024 0.0315 0.0315
Schistosoma mansoni tubulin subunit beta 0.0214 0.0275 0.0624
Loa Loa (eye worm) hypothetical protein 0.0103 0.0105 0.0105
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0132 0.015 0.0271
Brugia malayi sulfakinin receptor protein 0.024 0.0315 0.0315
Echinococcus granulosus allatostatin A receptor 0.024 0.0315 0.0568
Onchocerca volvulus 0.024 0.0315 0.0513
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Onchocerca volvulus 0.024 0.0315 0.0513
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0132 0.015 0.5
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0224 0.0291 0.0291
Onchocerca volvulus 0.0554 0.0796 0.2813
Brugia malayi G protein-coupled receptor F59B2.13 0.024 0.0315 0.0315
Brugia malayi AKH receptor 0.024 0.0315 0.0315
Echinococcus granulosus rhodopsin orphan GPCR 0.024 0.0315 0.0568
Trypanosoma cruzi Heat shock protein 83, putative 0.0146 0.0171 0.6238
Schistosoma mansoni biogenic amine (dopamine) receptor 0.024 0.0315 0.0715
Loa Loa (eye worm) hypothetical protein 0.0224 0.0291 0.0291
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0072 0.0057 0.0057
Loa Loa (eye worm) apoptosis regulator protein 0.0224 0.0291 0.0291
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0242 0.0318 0.0574
Trypanosoma brucei heat shock protein, putative 0.0146 0.0171 0.6238
Loa Loa (eye worm) TYRA-2 protein 0.024 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus granulosus neuropeptide Y receptor 0.024 0.0315 0.0568
Brugia malayi GnHR receptor homolog 0.024 0.0315 0.0315
Echinococcus granulosus adenylate cyclase 9 0.0554 0.0796 0.1436
Echinococcus granulosus heat shock protein 90 0.0146 0.0171 0.0309
Schistosoma mansoni hypothetical protein 0.0224 0.0291 0.0661
Loa Loa (eye worm) latrophilin receptor protein 2 0.1361 0.2034 0.2034
Brugia malayi hypothetical protein 0.024 0.0315 0.0315
Echinococcus multilocularis orexin receptor type 2 0.024 0.0315 0.0568
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.365 0.5544 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0224 0.0291 0.0661
Trypanosoma brucei heat shock protein, putative 0.0146 0.0171 0.6238
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.024 0.0315 0.0568
Echinococcus granulosus GPCR family 2 0.1361 0.2034 0.3668
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.1361 0.2034 0.3668
Echinococcus granulosus neuropeptide receptor 0.024 0.0315 0.0568
Loa Loa (eye worm) G-protein coupled receptor 0.024 0.0315 0.0315
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0344 1
Schistosoma mansoni opsin-like receptor 0.024 0.0315 0.0715
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0207 0.6033
Schistosoma mansoni endoplasmin 0.0146 0.0171 0.0389
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Echinococcus granulosus peptide allatostatin:somatostatin 0.024 0.0315 0.0568
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Loa Loa (eye worm) integrin beta-2 0.058 0.0837 0.0837
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0072 0.0057 0.1802
Brugia malayi Tubulin beta-1 chain 0.0214 0.0275 0.0275
Trichomonas vaginalis tubulin gamma chain, putative 0.0214 0.0275 0.7996
Schistosoma mansoni hypothetical protein 0.024 0.0315 0.0715
Trypanosoma brucei heat shock protein, putative 0.0146 0.0171 0.6238
Treponema pallidum heat shock protein 90 0.0132 0.015 0.5
Entamoeba histolytica tubulin family protein 0.0214 0.0275 1
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0344 1
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.024 0.0315 0.0315
Echinococcus granulosus rhodopsin orphan GPCR 0.024 0.0315 0.0568
Trypanosoma brucei beta tubulin 0.0214 0.0275 1
Echinococcus multilocularis neuropeptides capa receptor 0.024 0.0315 0.0568
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.024 0.0315 0.0568
Onchocerca volvulus 0.024 0.0315 0.0513
Schistosoma mansoni tubulin subunit beta 0.0214 0.0275 0.0624
Brugia malayi Integrin beta pat-3 precursor 0.058 0.0837 0.0837
Schistosoma mansoni rhodopsin-like orphan GPCR 0.024 0.0315 0.0715
Trichomonas vaginalis glucosylceramidase, putative 0.017 0.0207 0.6033
Echinococcus multilocularis serotonin receptor 0.024 0.0315 0.0568
Trypanosoma brucei heat shock protein, putative 0.0146 0.0171 0.6238
Echinococcus granulosus tm gpcr rhodopsin 0.024 0.0315 0.0568
Schistosoma mansoni neuropeptide receptor 0.126 0.1879 0.4267
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0344 1
Toxoplasma gondii beta-tubulin, putative 0.0214 0.0275 0.0454
Schistosoma mansoni heat shock protein 0.0146 0.0171 0.0389
Loa Loa (eye worm) heat shock protein 90 0.0146 0.0171 0.0171
Echinococcus granulosus dro:myosuppressin receptor 0.024 0.0315 0.0568
Trypanosoma brucei heat shock protein 90, putative 0.0146 0.0171 0.6238
Echinococcus multilocularis beta tubulin 0.0214 0.0275 0.0496
Echinococcus granulosus sex peptide receptor 0.024 0.0315 0.0568
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Trichomonas vaginalis heat shock protein, putative 0.0042 0.0011 0.0318
Echinococcus multilocularis neuropeptide receptor 0.024 0.0315 0.0568
Schistosoma mansoni adenoreceptor 0.024 0.0315 0.0715
Echinococcus multilocularis rhodopsin orphan GPCR 0.024 0.0315 0.0568
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Schistosoma mansoni neuropeptide F-like receptor 0.024 0.0315 0.0715
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.024 0.0315 0.0568
Brugia malayi Latrophilin receptor protein 2 0.1361 0.2034 0.2034
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0344 1
Schistosoma mansoni neuropeptide F-like receptor 0.024 0.0315 0.0715
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Trichomonas vaginalis STE family protein kinase 0.0072 0.0057 0.1669
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.2809 0.4254 0.7673
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0044 0.0015 0.0446
Echinococcus granulosus neuropeptide s receptor 0.024 0.0315 0.0568
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.024 0.0315 0.0568
Schistosoma mansoni neuropeptide receptor 0.024 0.0315 0.0715
Brugia malayi hypothetical protein 0.024 0.0315 0.0315
Echinococcus multilocularis neuropeptide Y receptor 0.024 0.0315 0.0568
Echinococcus multilocularis sodium channel protein 0.0242 0.0318 0.0574
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Echinococcus multilocularis dro:myosuppressin receptor 0.024 0.0315 0.0568
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0049 0.0022 0.0647
Schistosoma mansoni rhodopsin-like orphan GPCR 0.024 0.0315 0.0715
Schistosoma mansoni hypothetical protein 0.1361 0.2034 0.4619
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0049 0.0022 0.0037
Schistosoma mansoni neuropeptide f receptor 76f 0.024 0.0315 0.0715
Schistosoma mansoni serine-type protease inhibitor 0.0457 0.0648 0.1471
Trypanosoma cruzi heat shock protein 90, putative 0.0146 0.0171 0.6238
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.024 0.0315 0.0315
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0242 0.0318 1
Echinococcus granulosus g-protein coupled receptor 0.024 0.0315 0.0568
Onchocerca volvulus 0.024 0.0315 0.0513
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.024 0.0315 0.0568
Echinococcus granulosus biogenic amine 5HT receptor 0.024 0.0315 0.0568
Echinococcus multilocularis alpha 1A adrenergic receptor 0.024 0.0315 0.0568
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0072 0.0057 0.0057
Schistosoma mansoni biogenic amine (5HT) receptor 0.024 0.0315 0.0715
Brugia malayi Adenylyl cyclase protein 0.0554 0.0796 0.0796
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0167 0.0203 0.0365
Echinococcus granulosus histone acetyltransferase KAT2B 0.0049 0.0022 0.004
Brugia malayi latrophilin 2 splice variant baaae 0.2906 0.4403 0.4403
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Echinococcus granulosus sodium channel protein 0.0242 0.0318 0.0574
Echinococcus multilocularis rhodopsin orphan GPCR 0.024 0.0315 0.0568
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Echinococcus multilocularis GPCR, family 2 0.1361 0.2034 0.3668
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0049 0.1765
Echinococcus multilocularis rhodopsin orphan GPCR 0.024 0.0315 0.0568
Onchocerca volvulus 0.024 0.0315 0.0513
Trichomonas vaginalis bromodomain-containing protein, putative 0.0049 0.0022 0.0647
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0049 0.1765
Echinococcus multilocularis sex peptide receptor 0.024 0.0315 0.0568
Leishmania major beta tubulin 0.0214 0.0275 0.8631
Loa Loa (eye worm) endoplasmin 0.0146 0.0171 0.0171
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus granulosus Tubulin beta 2C chain 0.0214 0.0275 0.0496
Schistosoma mansoni biogenic amine (dopamine) receptor 0.024 0.0315 0.0715
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.024 0.0315 0.0715
Schistosoma mansoni amine GPCR 0.024 0.0315 0.0715
Echinococcus granulosus tm gpcr rhodopsin 0.024 0.0315 0.0568
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.1534 0.2299 1
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus granulosus neuropeptides capa receptor 0.024 0.0315 0.0568
Schistosoma mansoni serine-type protease inhibitor 0.0457 0.0648 0.1471
Giardia lamblia Histone acetyltransferase GCN5 0.0045 0.0016 0.0582
Schistosoma mansoni apoptosis regulator bax 0.0224 0.0291 0.0661
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.024 0.0315 0.0568
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0015 0.0558
Trypanosoma cruzi heat shock protein 85, putative 0.0146 0.0171 0.6238
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0259 0.0344 0.0344
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Trichomonas vaginalis tubulin epsilon chain, putative 0.0214 0.0275 0.7996
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.024 0.0315 0.0568
Mycobacterium ulcerans heat shock protein 90 0.0132 0.015 1
Trypanosoma brucei heat shock protein, putative 0.0146 0.0171 0.6238
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Brugia malayi gonadotropin-releasing hormone receptor 2 0.024 0.0315 0.0315
Echinococcus multilocularis neuropeptide s receptor 0.024 0.0315 0.0568
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.024 0.0315 0.0568
Echinococcus multilocularis neuropeptide receptor A26 0.024 0.0315 0.0568
Giardia lamblia Grp94/Hsp90 0.0132 0.015 0.5467
Trypanosoma brucei beta tubulin 0.0214 0.0275 1
Brugia malayi neuropeptide F receptor 0.024 0.0315 0.0315
Schistosoma mansoni protein kinase 0.0072 0.0057 0.013
Trichomonas vaginalis heat shock protein, putative 0.0146 0.0171 0.4987
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.024 0.0315 0.0315
Echinococcus granulosus tm gpcr rhodopsin 0.024 0.0315 0.0568
Schistosoma mansoni tubulin subunit beta 0.0214 0.0275 0.0624
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus granulosus endoplasmin 0.0132 0.015 0.0271
Echinococcus granulosus rhodopsin orphan GPCR 0.024 0.0315 0.0568
Loa Loa (eye worm) hypothetical protein 0.053 0.0759 0.0759
Echinococcus granulosus adenylate cyclase type IX 0.0194 0.0245 0.0442
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Schistosoma mansoni hypothetical protein 0.024 0.0315 0.0715
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.0015 0.0558
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0344 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0049 0.1765
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Trypanosoma brucei heat shock protein, putative 0.0146 0.0171 0.6238
Echinococcus multilocularis tubulin beta 1 chain 0.0214 0.0275 0.0496
Onchocerca volvulus 0.024 0.0315 0.0513
Brugia malayi Kelch motif family protein 0.0103 0.0105 0.0105
Brugia malayi beta-tubulin, identical 0.0214 0.0275 0.0275
Trypanosoma brucei heat shock protein, putative 0.0146 0.0171 0.6238
Trichomonas vaginalis glucosylceramidase, putative 0.0259 0.0344 1
Trichomonas vaginalis endoplasmin, putative 0.0042 0.0011 0.0318
Onchocerca volvulus 0.053 0.076 0.2641
Echinococcus granulosus orexin receptor type 2 0.024 0.0315 0.0568
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.024 0.0315 0.0568
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Brugia malayi Tachykinin-like peptides receptor 99D 0.024 0.0315 0.0315
Echinococcus multilocularis somatostatin receptor 0.024 0.0315 0.0568
Loa Loa (eye worm) melatonin receptor type 1A 0.024 0.0315 0.0315
Schistosoma mansoni amine GPCR 0.024 0.0315 0.0715
Echinococcus granulosus 7TM GPCR rhodopsin 0.024 0.0315 0.0568
Loa Loa (eye worm) tubulin beta chain 0.0214 0.0275 0.0275
Schistosoma mansoni biogenic amine receptor 0.024 0.0315 0.0715
Trichomonas vaginalis tubulin epsilon chain, putative 0.0214 0.0275 0.7996
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Echinococcus granulosus somatostatin receptor 0.024 0.0315 0.0568
Schistosoma mansoni biogenic amine (dopamine) receptor 0.024 0.0315 0.0715
Leishmania major heat shock protein 83-1 0.0146 0.0171 0.5383
Schistosoma mansoni neuropeptide receptor 0.024 0.0315 0.0715
Loa Loa (eye worm) adenylyl cyclase 3 0.0724 0.1058 0.1058
Loa Loa (eye worm) hypothetical protein 0.024 0.0315 0.0315
Trypanosoma brucei heat shock protein, putative 0.0146 0.0171 0.6238
Schistosoma mansoni alpha-1 adrenergic receptor 0.024 0.0315 0.0715
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0015 0.0558

Activities

Activity type Activity value Assay description Source Reference
-log(1/MIC) (functional) = 1.22 Antibacterial activity against Escherichia coli MTCC 1652 after 24 hrs ChEMBL. 17428669
-log(1/MIC) (functional) = 1.22 Antibacterial activity against Escherichia coli MTCC 1652 after 24 hrs ChEMBL. 17428669
-log(1/MIC) (functional) = 1.25 Antibacterial activity against Bacillus subtilis MTCC 2063 after 24 hrs ChEMBL. 17428669
-log(1/MIC) (functional) = 1.32 Antibacterial activity against Staphylococcus aureus MTCC 290 after 24 hrs ChEMBL. 17428669
-log(1/MIC) (functional) = 1.57 Antifungal activity against Aspergillus ficuum MTCC 8184 by serial dilution method ChEMBL. 17428669
-log(1/MIC) (functional) = 1.62 Antifungal activity against Aspergillus parasiticus MTCC 8189 by serial dilution method ChEMBL. 17428669

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.