Detailed information for compound 433780

Basic information

Technical information
  • TDR Targets ID: 433780
  • Name: 4-bromo-3-(carboxymethyloxy)-5-(3-phenylmetho xyphenyl)thiophene-2-carboxylic acid
  • MW: 463.298 | Formula: C20H15BrO6S
  • H donors: 2 H acceptors: 4 LogP: 4.85 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)COc1c(Br)c(sc1C(=O)O)c1cccc(c1)OCc1ccccc1
  • InChi: 1S/C20H15BrO6S/c21-16-17(27-11-15(22)23)19(20(24)25)28-18(16)13-7-4-8-14(9-13)26-10-12-5-2-1-3-6-12/h1-9H,10-11H2,(H,22,23)(H,24,25)
  • InChiKey: GSQNETMICDITMP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 5-(3-benzyloxyphenyl)-4-bromo-3-(carboxymethyloxy)thiophene-2-carboxylic acid
  • 5-(3-benzyloxyphenyl)-4-bromo-3-(carboxymethyloxy)-2-thiophenecarboxylic acid
  • 5-(3-benzoxyphenyl)-4-bromo-3-(carboxymethyloxy)-2-thenoic acid

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens protein tyrosine phosphatase, non-receptor type 1 Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) protein-tyrosine phosphatase Get druggable targets OG5_133865 All targets in OG5_133865
Echinococcus multilocularis tyrosine protein phosphatase non receptor type Get druggable targets OG5_133865 All targets in OG5_133865
Schistosoma japonicum ko:K05696 protein tyrosine phosphatase, non-receptor type 1, putative Get druggable targets OG5_133865 All targets in OG5_133865
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 Get druggable targets OG5_133865 All targets in OG5_133865
Echinococcus granulosus tyrosine protein phosphatase non receptor type Get druggable targets OG5_133865 All targets in OG5_133865
Schistosoma japonicum expressed protein Get druggable targets OG5_133865 All targets in OG5_133865
Brugia malayi Protein-tyrosine phosphatase containing protein Get druggable targets OG5_133865 All targets in OG5_133865
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0019 0.0071 0.0133
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0263 0.0629
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0195 0.224 0.5351
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.041 0.098
Trichomonas vaginalis replication factor C large subunit, putative 0.0019 0.0071 0.0169
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0068 0.4696
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0071 0.0169
Entamoeba histolytica hypothetical protein 0.0035 0.0259 0.0619
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0071 0.0169
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.024 0.5844
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0071 0.0169
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0068 0.0163
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.024 0.5844
Mycobacterium ulcerans hypothetical protein 0.0047 0.041 1
Schistosoma mansoni topbp1 0.0019 0.0071 0.014
Loa Loa (eye worm) transcription factor SMAD2 0.0115 0.1256 0.1469
Loa Loa (eye worm) macrophage migration inhibitory factor 0.0352 0.4187 0.4899
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0019 0.0071 0.0169
Schistosoma mansoni topbp1 0.0019 0.0071 0.014
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0263 0.6421
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0068 0.4696
Brugia malayi Pax transcription activation domain interacting protein 0.0019 0.0071 0.0083
Echinococcus multilocularis sterol regulatory element binding protein 0.0084 0.0864 0.0864
Loa Loa (eye worm) hypothetical protein 0.0443 0.5312 0.6215
Schistosoma mansoni hypothetical protein 0.0081 0.0827 0.1633
Loa Loa (eye worm) hypothetical protein 0.0047 0.041 0.048
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0019 0.0071 0.0169
Echinococcus granulosus dna polymerase eta 0.0019 0.0068 0.008
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.041 1
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0624 0.0624
Toxoplasma gondii ATPase, AAA family protein 0.0019 0.0071 0.0169
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0068 0.0068
Brugia malayi hypothetical protein 0.0705 0.8547 1
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0019 0.0071 0.1722
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0146 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0068 0.0163
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.041 1
Brugia malayi RNA binding protein 0.0064 0.0624 0.073
Loa Loa (eye worm) RNA binding protein 0.0064 0.0624 0.073
Brugia malayi hypothetical protein 0.0019 0.0071 0.0083
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0259 0.0303
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0864 0.2064
Echinococcus multilocularis dna polymerase eta 0.0019 0.0068 0.0068
Leishmania major DNA polymerase eta, putative 0.0019 0.0068 0.0163
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0068 0.4696
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0423 0.5062 0.5923
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0624 0.1233
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.041 0.098
Echinococcus multilocularis protein patched 0.0084 0.0864 0.0864
Loa Loa (eye worm) hypothetical protein 0.0019 0.0071 0.0083
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.041 0.098
Echinococcus granulosus Niemann Pick C1 protein 0.0279 0.3275 0.3832
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0068 0.4696
Schistosoma mansoni DNA polymerase eta 0.0019 0.0068 0.0135
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0068 0.1668
Leishmania major macrophage migration inhibitory factor-like protein 0.0352 0.4187 1
Plasmodium vivax replication factor C subunit 1, putative 0.0019 0.0071 0.0169
Leishmania major DNA polymerase kappa, putative 0.0019 0.0068 0.0163
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0068 0.4696
Loa Loa (eye worm) hypothetical protein 0.0195 0.224 0.2621
Echinococcus granulosus nibrin 0.0019 0.0071 0.0083
Echinococcus granulosus Protein patched homolog 1 0.0084 0.0864 0.1011
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0068 0.008
Loa Loa (eye worm) macrophage migration inhibitory factor 2 0.015 0.1688 0.1975
Echinococcus multilocularis Niemann Pick C1 protein 0.0195 0.224 0.224
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0068 0.1668
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0624 0.1233
Plasmodium vivax macrophage migration inhibitory factor, putative 0.0352 0.4187 1
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0423 0.5062 0.5062
Brugia malayi hypothetical protein 0.0017 0.0034 0.0039
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0068 0.4696
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0263 0.6421
Entamoeba histolytica hypothetical protein 0.0035 0.0259 0.0619
Trypanosoma brucei unspecified product 0.0019 0.0068 0.4696
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.041 0.098
Brugia malayi DKFZp564C0469 protein 0.0019 0.0071 0.0083
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.041 0.098
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0423 0.5062 0.5923
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0423 0.5062 0.5923
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.024 0.5844
Brugia malayi hypothetical protein 0.0026 0.0146 0.017
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0068 0.4696
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0068 0.0163
Echinococcus multilocularis Protein lozenge 0.0056 0.0517 0.0517
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0019 0.0071 0.1722
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0263 0.0629
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0019 0.0071 0.0083
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.041 1
Schistosoma mansoni chromosome transmission fidelity factor 0.0019 0.0071 0.014
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0423 0.5062 1
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0019 0.0071 0.0169
Brugia malayi TAR-binding protein 0.0064 0.0624 0.073
Loa Loa (eye worm) hypothetical protein 0.0047 0.041 0.048
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0068 0.0163
Echinococcus granulosus expressed conserved protein 0.0183 0.2094 0.245
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0019 0.0071 0.5
Echinococcus multilocularis expressed conserved protein 0.0183 0.2094 0.2094
Schistosoma mansoni DNA ligase IV 0.0019 0.0071 0.014
Giardia lamblia Macrophage migration inhibitory factor 0.0352 0.4187 1
Brugia malayi AMP-binding enzyme family protein 0.0047 0.041 0.048
Giardia lamblia Replication factor C, subunit 1 0.0019 0.0071 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0071 0.4848
Echinococcus granulosus Niemann Pick C1 protein 0.0195 0.224 0.2621
Brugia malayi Bm-MIF-1, identical 0.0352 0.4187 0.4899
Brugia malayi Niemann-Pick C1 protein precursor 0.0195 0.224 0.2621
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0071 0.4848
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0263 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0068 0.4696
Loa Loa (eye worm) MH2 domain-containing protein 0.0115 0.1256 0.1469
Entamoeba histolytica hypothetical protein 0.0035 0.0259 0.0619
Brugia malayi hypothetical protein 0.0019 0.0071 0.0083
Loa Loa (eye worm) hypothetical protein 0.0047 0.041 0.048
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0068 0.008
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0071 0.0169
Toxoplasma gondii macrophage migration inhibitory factor, putative 0.0352 0.4187 1
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0259 0.0512
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.041 0.098
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0146 0.0348
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0068 0.008
Entamoeba histolytica hypothetical protein 0.0019 0.0071 0.0169
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.041 1
Plasmodium falciparum macrophage migration inhibitory factor 0.0352 0.4187 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0259 0.0259
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.041 1
Echinococcus multilocularis replication factor c subunit 1 0.0019 0.0071 0.0071
Onchocerca volvulus 0.0144 0.1608 0.3026
Brugia malayi AMP-binding enzyme family protein 0.0047 0.041 0.048
Loa Loa (eye worm) hypothetical protein 0.0019 0.0068 0.008
Loa Loa (eye worm) hypothetical protein 0.0035 0.0263 0.0308
Loa Loa (eye worm) hypothetical protein 0.0035 0.0263 0.0308
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0068 0.4696
Echinococcus multilocularis protein dispatched 1 0.0095 0.101 0.101
Echinococcus granulosus replication factor c subunit 1 0.0019 0.0071 0.0083
Schistosoma mansoni survival motor neuron protein 0.0144 0.1608 0.3176
Treponema pallidum DNA ligase (lig) 0.0019 0.0071 0.5
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0019 0.0071 0.0169
Loa Loa (eye worm) hypothetical protein 0.0026 0.0146 0.017
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0146 0.0348
Trichomonas vaginalis conserved hypothetical protein 0.0352 0.4187 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.041 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0146 1
Schistosoma mansoni hypothetical protein 0.0081 0.0827 0.1633
Schistosoma mansoni hypothetical protein 0.0144 0.1608 0.3176
Echinococcus granulosus tar DNA binding protein 0.0064 0.0624 0.073
Brugia malayi CHE-14 protein 0.0084 0.0864 0.1011
Brugia malayi topoisomerase 0.0019 0.0071 0.0083
Echinococcus granulosus survival motor neuron protein 1 0.0705 0.8547 1
Trypanosoma cruzi hypothetical protein, conserved 0.0019 0.0071 0.4848
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0624 0.1233
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0068 0.4696
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0019 0.0071 0.0169
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0146 0.0348
Loa Loa (eye worm) hypothetical protein 0.0035 0.0263 0.0308
Schistosoma mansoni patched 1 0.0084 0.0864 0.1707
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.041 1
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0019 0.0071 0.0169
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.024 0.5844
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0084 0.0864 0.1011
Loa Loa (eye worm) hypothetical protein 0.0019 0.0071 0.0083
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.041 1
Loa Loa (eye worm) hypothetical protein 0.0084 0.0864 0.1011
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0068 0.0135
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.041 1
Echinococcus multilocularis Niemann Pick C1 protein 0.0279 0.3275 0.3275
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0068 0.1668
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0624 0.073
Echinococcus multilocularis survival motor neuron protein 1 0.0705 0.8547 0.8547
Loa Loa (eye worm) hypothetical protein 0.0035 0.0263 0.0308
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0624 0.1233
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0068 0.4696
Brugia malayi AMP-binding enzyme family protein 0.0047 0.041 0.048
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0624 0.1233
Loa Loa (eye worm) macrophage migration inhibitory factor 2 0.015 0.1688 0.1975
Entamoeba histolytica hypothetical protein 0.0035 0.0259 0.0619
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0071 0.0169
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0068 0.4696
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0068 0.4696
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0068 0.4696
Loa Loa (eye worm) hypothetical protein 0.0019 0.0071 0.0083
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0144 0.1608 0.1881
Loa Loa (eye worm) hypothetical protein 0.0019 0.0071 0.0083
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0624 0.073
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0705 0.8547 1
Loa Loa (eye worm) runx1 0.0056 0.0517 0.0605
Loa Loa (eye worm) hypothetical protein 0.0443 0.5312 0.6215
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0146 1
Schistosoma mansoni hypothetical protein 0.0081 0.0827 0.1633
Schistosoma mansoni hypothetical protein 0.0035 0.0259 0.0512
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0068 0.1668
Brugia malayi hypothetical protein 0.0035 0.0259 0.0303
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0019 0.0071 0.4848
Entamoeba histolytica macrophage migration inhibitory factor-like protein 0.0352 0.4187 1
Plasmodium falciparum replication factor C subunit 1, putative 0.0019 0.0071 0.0169
Echinococcus granulosus sterol regulatory element binding protein 0.0084 0.0864 0.1011
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0068 0.4696
Loa Loa (eye worm) hypothetical protein 0.0019 0.0071 0.0083
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0068 0.0135
Leishmania major macrophage migration inhibitory factor-like protein 0.0352 0.4187 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0068 0.4696
Schistosoma mansoni hypothetical protein 0.0081 0.0827 0.1633
Trypanosoma cruzi FHA domain containing protein, putative 0.0019 0.0071 0.4848
Brugia malayi hypothetical protein 0.0443 0.5312 0.6215
Loa Loa (eye worm) hypothetical protein 0.0019 0.0071 0.0083
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0146 0.0348
Loa Loa (eye worm) hypothetical protein 0.0103 0.1097 0.1283
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.041 1
Echinococcus multilocularis nibrin 0.0019 0.0071 0.0071
Trichomonas vaginalis macrophage migration inhibitory factor, mif, putative 0.0352 0.4187 1
Echinococcus granulosus dna polymerase kappa 0.0019 0.0068 0.008
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.041 1
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0624 0.073
Onchocerca volvulus 0.0443 0.5312 1
Leishmania major hypothetical protein, conserved 0.0026 0.0146 0.0348
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0068 0.4696
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0068 0.4696
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0198 0.2278 0.4499
Loa Loa (eye worm) hypothetical protein 0.0035 0.0263 0.0308
Brugia malayi MH2 domain containing protein 0.0115 0.1256 0.1469
Onchocerca volvulus 0.0047 0.041 0.0772
Schistosoma mansoni lozenge 0.0056 0.0517 0.1022
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0068 0.4696
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0068 0.008

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 0.68 uM Inhibition of human recombinant PTP1B ChEMBL. 17705360
Ki (binding) = 0.68 uM Inhibition of human recombinant PTP1B ChEMBL. 17705360

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.