Detailed information for compound 569336

Basic information

Technical information
  • TDR Targets ID: 569336
  • Name: cobaltic ammonia azide iodide
  • MW: 315.026 | Formula: CoH17IN8+
  • H donors: 5 H acceptors: 0 LogP: -1.28 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: [NH-]=[N+]=[NH-].[Co+3].[I-].N.N.N.N.N
  • InChi: 1S/Co.HI.N3.5H3N/c;;1-3-2;;;;;/h;1H;;5*1H3/q+3;;-1;;;;;/p-1
  • InChiKey: TVJVAPNQAXAWRT-UHFFFAOYSA-M  


Substructure search Similarity search

Network

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Synonyms

  • azane; cobalt(3+); azide; iodide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans hypothetical protein 0.0023 0.0395 1
Entamoeba histolytica serine/threonine protein kinase, putative 0.0104 0.4264 1
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0395 1
Schistosoma mansoni hypothetical protein 0.0017 0.0114 0.0182
Brugia malayi hypothetical protein 0.007 0.2623 0.2538
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0104 0.4264 0.515
Schistosoma mansoni troponin t invertebrate 0.0146 0.6269 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.108 0.1006
Loa Loa (eye worm) hypothetical protein 0.0118 0.4915 0.4873
Schistosoma mansoni zinc finger protein 0.0019 0.0201 0.032
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0395 0.0284
Brugia malayi serine/threonine-protein kinase plk-2 0.0104 0.4264 0.4198
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0104 0.4264 0.515
Giardia lamblia Kinase, PLK 0.0104 0.4264 0.5
Schistosoma mansoni hypothetical protein 0.002 0.025 0.0399
Brugia malayi Troponin T 0.007 0.2623 0.2538
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0395 1
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0395 1
Echinococcus multilocularis oncosphere protein tso22e oncosphere protein tso22d oncosphere protein tso22c oncosphere protein tso22b oncosphere protein tso22 0.0146 0.6269 0.7619
Loa Loa (eye worm) hypothetical protein 0.0118 0.4915 0.4873
Loa Loa (eye worm) hypothetical protein 0.004 0.1194 0.112
Loa Loa (eye worm) PHD-finger family protein 0.002 0.025 0.0169
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0114 0.0039
Loa Loa (eye worm) troponin I 0.0118 0.4915 0.4873
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0395 1
Brugia malayi Troponin T 0.007 0.2623 0.2538
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0104 0.4264 0.4217
Schistosoma mansoni hypothetical protein 0.0017 0.0114 0.0182
Echinococcus granulosus troponin i 0.0118 0.4915 0.5951
Loa Loa (eye worm) hypothetical protein 0.0017 0.0113 0.0031
Onchocerca volvulus Troponin I homolog 0.0118 0.4915 0.7694
Plasmodium vivax acyl-CoA synthetase, putative 0.0017 0.0113 0.5
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0395 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0114 0.0032
Loa Loa (eye worm) hypothetical protein 0.0042 0.1283 0.1211
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0082 0.0131
Echinococcus granulosus oncosphere protein Tso22e 0.0146 0.6269 0.7619
Loa Loa (eye worm) hypothetical protein 0.0023 0.0395 0.0315
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0187 0.8203 1
Schistosoma mansoni troponin I 0.0118 0.4915 0.7839
Echinococcus multilocularis troponin i 0.0118 0.4915 0.5951
Loa Loa (eye worm) hypothetical protein 0.0023 0.0395 0.0315
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0395 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0104 0.4264 1
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.4264 1
Trypanosoma brucei polo-like protein kinase 0.0104 0.4264 1
Loa Loa (eye worm) troponin 0.007 0.2623 0.2562
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.4264 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0395 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0104 0.4264 1
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0111 0.0029
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0017 0.0113 0.139
Schistosoma mansoni troponin I 0.0118 0.4915 0.7839
Schistosoma mansoni hypothetical protein 0.0038 0.108 0.1722
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.4264 1
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0022 0.034 0.0317
Loa Loa (eye worm) hypothetical protein 0.0017 0.0114 0.0032
Schistosoma mansoni bromodomain containing protein 0.0062 0.2251 0.3591
Onchocerca volvulus Troponin T, skeletal muscle homolog 0.0146 0.6269 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0968 0.1091
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0395 0.0284
Echinococcus multilocularis GPCR, family 2 0.0017 0.0114 0.0039
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.4264 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0968 0.1091
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0055 0.1912 0.1844
Schistosoma mansoni troponin I 0.0118 0.4915 0.7839
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0395 0.0925
Brugia malayi Calcitonin receptor-like protein seb-1 0.0055 0.1912 0.1818
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0017 0.0113 0.5
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0059 0.2083 0.2464
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0082 0.0131
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0082 0.0131
Loa Loa (eye worm) hypothetical protein 0.0069 0.26 0.2539
Brugia malayi Bromodomain containing protein 0.0038 0.1079 0.0976
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0395 1
Echinococcus granulosus zinc finger protein 0.0019 0.0201 0.0146
Loa Loa (eye worm) hypothetical protein 0.0023 0.0395 0.0315
Loa Loa (eye worm) hypothetical protein 0.0224 1 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0059 0.2083 0.2464
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0104 0.4264 1
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.108 0.0977
Schistosoma mansoni kinase 0.0053 0.1814 0.2894
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0187 0.8203 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0395 0.0925
Brugia malayi Troponin I 0.0118 0.4915 0.4856
Brugia malayi PHD-finger family protein 0.0024 0.0451 0.0341
Brugia malayi Bromodomain containing protein 0.0074 0.2801 0.2718
Loa Loa (eye worm) hypothetical protein 0.007 0.2623 0.2562
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0395 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0113 0.0031
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0395 0.0925
Loa Loa (eye worm) hypothetical protein 0.0017 0.0113 0.0031
Loa Loa (eye worm) hypothetical protein 0.0038 0.1083 0.1008
Brugia malayi Troponin family protein 0.0118 0.4915 0.4856
Onchocerca volvulus Serine\/threonine kinase homolog 0.0104 0.4264 0.6587
Onchocerca volvulus Troponin T, skeletal muscle homolog 0.007 0.2623 0.3794
Echinococcus multilocularis zinc finger protein 0.0019 0.0201 0.0146
Plasmodium falciparum acyl-CoA synthetase 0.0017 0.0113 0.5
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0114 0.0039
Schistosoma mansoni hypothetical protein 0.0017 0.0114 0.0182
Brugia malayi Troponin T 0.007 0.2623 0.2538
Schistosoma mansoni hypothetical protein 0.0118 0.4915 0.7839
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.4264 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0395 0.5
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0395 0.0284
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0022 0.034 0.0542
Echinococcus granulosus GPCR family 2 0.0017 0.0114 0.0039
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.4264 0.6802
Loa Loa (eye worm) hypothetical protein 0.0017 0.0113 0.0031
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0395 0.5
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0082 0.0131
Loa Loa (eye worm) troponin T 0.007 0.2623 0.2562
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.4264 1
Echinococcus granulosus fetal alzheimer antigen falz 0.0022 0.034 0.0317
Loa Loa (eye worm) hypothetical protein 0.0017 0.0113 0.0031
Schistosoma mansoni hypothetical protein 0.0017 0.0114 0.0182
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.4264 1
Schistosoma mansoni troponin I 0.0118 0.4915 0.7839

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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