TDR Targets

Basic information

Technical information

TDR Targets ID: 579039
Name: 2-[carboxymethyl(formyl)amino]acetic acid
MW: 161.113 | Formula: C5H7NO5
H donors: 2 H acceptors: 5 LogP: -1.07 Rotable bonds: 5
Rule of 5 violations (Lipinski): 1
SMILES: O=CN(CC(=O)O)CC(=O)O
InChi: 1S/C5H7NO5/c7-3-6(1-4(8)9)2-5(10)11/h3H,1-2H2,(H,8,9)(H,10,11)
InChiKey: XQFGONUUVRQZKA-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

2-[carboxymethyl(methanoyl)amino]ethanoic acid
N-formyliminodiacetic acid
2-(carboxymethyl-formylamino)acetic acid
2-(carboxymethyl-formyl-amino)acetic acid
2-(carboxymethyl-methanoyl-amino)ethanoic acid
71449-79-1
Glycine, N-(carboxymethyl)-N-formyl-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0039	0.0329	0.0303
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0199	0.0773
Echinococcus granulosus	lysine specific demethylase 5A	0.0039	0.0329	0.0329
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0016	0.0026	0.0103
Trypanosoma cruzi	hypothetical protein, conserved	0.0064	0.0659	1
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0048	0.045	0.045
Loa Loa (eye worm)	phosphotyrosine protein phosphatase	0.0207	0.257	1
Schistosoma mansoni	jumonji domain containing protein	0.0084	0.0928	0.0904
Wolbachia endosymbiont of Brugia malayi	exonuclease III	0.0021	0.0086	0.5
Onchocerca volvulus		0.003	0.0206	0.0706
Echinococcus multilocularis	receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type	0.0016	0.0026	0.0026
Onchocerca volvulus		0.003	0.0206	0.0706
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Brugia malayi	hypothetical protein	0.0016	0.0026	0.0021
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0106	0.1218	0.1218
Brugia malayi	Protein-tyrosine phosphatase 1	0.0016	0.0026	0.0021
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0016	0.0026	0.0026
Loa Loa (eye worm)	jmjC domain-containing protein	0.0039	0.0329	0.128
Echinococcus multilocularis	receptor type tyrosine protein phosphatase F	0.0016	0.0026	0.0026
Brugia malayi	Dual specificity protein phosphatase CDC14B	0.0016	0.0026	0.0021
Echinococcus granulosus	Receptor type tyrosine protein phosphatase O	0.0016	0.0026	0.0026
Schistosoma mansoni	lamin	0.003	0.0206	0.018
Brugia malayi	intermediate filament protein	0.003	0.0206	0.0725
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0016	0.0026	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Brugia malayi	Low molecular weight phosphotyrosine protein phosphatase containing protein	0.0207	0.257	1
Toxoplasma gondii	PHD-finger domain-containing protein	0.0032	0.0238	1
Echinococcus granulosus	intermediate filament protein	0.003	0.0206	0.0206
Loa Loa (eye worm)	protein-tyrosine phosphatase 1	0.0016	0.0026	0.0103
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0016	0.0026	0.0026
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0016	0.0026	0.0026
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0016	0.0026	0.0026
Loa Loa (eye worm)	dual specificity protein phosphatase CDC14B	0.0016	0.0026	0.0103
Echinococcus multilocularis	lamin dm0	0.003	0.0206	0.0206
Brugia malayi	jmjC domain containing protein	0.0106	0.1218	0.4695
Trichomonas vaginalis	pps1 dual specificty phosphatase, putative	0.0641	0.837	1
Brugia malayi	Protein-tyrosine phosphatase	0.0016	0.0026	0.0021
Schistosoma mansoni	transcription factor LCR-F1	0.0074	0.0798	0.0773
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.0207	0.257	0.3049
Echinococcus multilocularis	jumonji domain containing protein	0.0045	0.0407	0.0407
Brugia malayi	hypothetical protein	0.0016	0.0026	0.0021
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0074	0.0798	0.0798
Loa Loa (eye worm)	hypothetical protein	0.0055	0.0546	0.2124
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0016	0.0026	0.0103
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0016	0.0026	0.0103
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.0207	0.257	0.3049
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.0064	0.0659	0.0759
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	0.0021	0.0086	0.0086
Brugia malayi	protein-tyrosine phosphatase Lar-like precursor, putative	0.0016	0.0026	0.0021
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0016	0.0026	0.0103
Loa Loa (eye worm)	protein-tyrosine-phosphatase	0.0016	0.0026	0.0103
Mycobacterium tuberculosis	Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase)	0.0143	0.1719	1
Schistosoma mansoni	ap endonuclease	0.0021	0.0086	0.0059
Echinococcus multilocularis	receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type	0.0016	0.0026	0.0026
Leishmania major	apurinic/apyrimidinic endonuclease-redox protein	0.0021	0.0086	0.0933
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0048	0.045	0.1683
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0048	0.045	0.045
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0016	0.0026	0.0026
Echinococcus multilocularis	lysine specific demethylase 5A	0.0039	0.0329	0.0329
Echinococcus multilocularis	Receptor type tyrosine protein phosphatase O	0.0016	0.0026	0.0026
Plasmodium vivax	hypothetical protein, conserved	0.0032	0.0238	1
Echinococcus multilocularis	Receptor type tyrosine protein phosphatase O	0.0016	0.0026	0.0026
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0016	0.0026	0.0026
Echinococcus granulosus	receptor type tyrosine protein phosphatase zeta	0.0016	0.0026	0.0026
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0016	0.0026	0.0026
Giardia lamblia	Endonuclease/Exonuclease/phosphatase	0.0021	0.0086	0.0232
Echinococcus multilocularis	receptor type tyrosine protein phosphatase H	0.0016	0.0026	0.0026
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Entamoeba histolytica	exodeoxyribonuclease III, putative	0.0021	0.0086	0.0071
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0016	0.0026	0.0103
Trypanosoma brucei	apurinic/apyrimidinic endonuclease, putative	0.0021	0.0086	0.0933
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0016	0.0026	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0016	0.0026	0.0026
Onchocerca volvulus	Alhambra homolog	0.0032	0.0238	0.0833
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	0.0021	0.0086	0.0333
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0074	0.0798	0.0798
Brugia malayi	Bromodomain containing protein	0.0032	0.0238	0.0852
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0141	0.1685	0.1685
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0016	0.0026	0.0026
Schistosoma mansoni	bromodomain-containing nuclear protein 1 brd1	0.0032	0.0238	0.0212
Echinococcus multilocularis	microtubule associated protein 2	0.0763	1	1
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0048	0.045	0.045
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0016	0.0026	0.0026
Entamoeba histolytica	hypothetical protein	0.0074	0.0798	0.0924
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0048	0.045	0.0425
Trichomonas vaginalis	low molecular weight protein-tyrosine-phosphatase, putative	0.0207	0.257	0.3049
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0238	0.0927
Brugia malayi	PHD-finger family protein	0.0032	0.0238	0.0852
Schistosoma mansoni	hypothetical protein	0.0032	0.0238	0.0212
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0048	0.045	0.0425
Brugia malayi	hypothetical protein	0.0016	0.0026	0.0021
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0016	0.0026	0.0103
Trichomonas vaginalis	low molecular weight protein-tyrosine-phosphatase, putative	0.0207	0.257	0.3049
Brugia malayi	hypothetical protein	0.0016	0.0026	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0016	0.0026	0.0103
Schistosoma mansoni	lamin	0.003	0.0206	0.018
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0016	0.0026	0.0026
Loa Loa (eye worm)	intermediate filament tail domain-containing protein	0.003	0.0206	0.0802
Trypanosoma cruzi	hypothetical protein, conserved	0.0064	0.0659	1
Mycobacterium ulcerans	phosphotyrosine protein phosphatase PtpA	0.0207	0.257	1
Echinococcus granulosus	lamin	0.003	0.0206	0.0206
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0016	0.0026	0.0026
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Echinococcus multilocularis	hypothetical protein	0.0016	0.0026	0.0026
Loa Loa (eye worm)	hypothetical protein	0.003	0.0206	0.0802
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Plasmodium falciparum	phd finger protein, putative	0.0032	0.0238	1
Echinococcus multilocularis	lamin	0.003	0.0206	0.0206
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0048	0.045	0.0425
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.0207	0.257	0.3049
Entamoeba histolytica	protein tyrosine phosphatase, putative	0.0207	0.257	0.3049
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0048	0.045	0.1752
Brugia malayi	Intermediate filament tail domain containing protein	0.003	0.0206	0.0725
Echinococcus multilocularis		0.0016	0.0026	0.0026
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0106	0.1218	0.1218
Echinococcus multilocularis	Receptor type tyrosine protein phosphatase O	0.0016	0.0026	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Schistosoma mansoni	intermediate filament proteins	0.003	0.0206	0.018
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0016	0.0026	0.0026
Leishmania major	hypothetical protein, conserved	0.0064	0.0659	1
Echinococcus multilocularis	receptor type tyrosine protein phosphatase zeta	0.0016	0.0026	0.0026
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0016	0.0026	0.0103
Echinococcus granulosus	lamin dm0	0.003	0.0206	0.0206
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Entamoeba histolytica	hypothetical protein	0.0074	0.0798	0.0924
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0141	0.1685	0.6556
Treponema pallidum	exodeoxyribonuclease (exoA)	0.0021	0.0086	0.5
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Entamoeba histolytica	hypothetical protein	0.0074	0.0798	0.0924
Loa Loa (eye worm)	protein tyrosine phosphatase	0.0016	0.0026	0.0103
Echinococcus multilocularis	protein tyrosine phosphatase n9	0.0016	0.0026	0.0026
Echinococcus granulosus	receptor type tyrosine protein phosphatase zeta	0.0016	0.0026	0.0026
Echinococcus granulosus	PHD finger protein rhinoceros	0.0032	0.0238	0.0238
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Echinococcus granulosus	protein tyrosine phosphatase n9	0.0016	0.0026	0.0026
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0016	0.0026	0.0026
Onchocerca volvulus		0.0207	0.257	1
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	0.0021	0.0086	0.0933
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Toxoplasma gondii	PHD-finger domain-containing protein	0.0032	0.0238	1
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0016	0.0026	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Brugia malayi	jmjC domain containing protein	0.0039	0.0329	0.1207
Echinococcus multilocularis	Receptor type tyrosine protein phosphatase O	0.0016	0.0026	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Schistosoma mansoni	protein tyrosine phosphatase n11 (shp2)	0.0141	0.1685	0.1663
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Loa Loa (eye worm)	intermediate filament protein	0.003	0.0206	0.0802
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0039	0.0329	0.0303
Loa Loa (eye worm)	fibronectin type III domain-containing protein	0.0016	0.0026	0.0103
Echinococcus multilocularis	peregrin	0.0032	0.0238	0.0238
Loa Loa (eye worm)	transcription factor SMAD2	0.012	0.1416	0.5507
Loa Loa (eye worm)	MH2 domain-containing protein	0.012	0.1416	0.5507
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0016	0.0026	0.0103
Entamoeba histolytica	hypothetical protein	0.0074	0.0798	0.0924
Giardia lamblia	PHD finger protein 15	0.0032	0.0238	0.0833
Echinococcus multilocularis	PHD finger protein rhinoceros	0.0032	0.0238	0.0238
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0141	0.1685	0.1685
Trichomonas vaginalis	ap endonuclease, putative	0.0021	0.0086	0.0071
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0016	0.0026	0.0026
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0016	0.0026	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Brugia malayi	exodeoxyribonuclease III family protein	0.0021	0.0086	0.0253
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0016	0.0026	0.0026
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	0.0021	0.0086	0.0086
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0141	0.1685	0.6527
Echinococcus granulosus	peregrin	0.0032	0.0238	0.0238
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0141	0.1685	0.1685
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Trichomonas vaginalis	ap endonuclease, putative	0.0021	0.0086	0.0071
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0016	0.0026	0.0103
Echinococcus granulosus	jumonji domain containing protein	0.0045	0.0407	0.0407
Brugia malayi	MH2 domain containing protein	0.012	0.1416	0.547
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Brugia malayi	hypothetical protein	0.0074	0.0798	0.3046
Echinococcus multilocularis	musashi	0.003	0.0206	0.0206
Loa Loa (eye worm)	cytoplasmic intermediate filament protein	0.0016	0.0021	0.0082
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0016	0.0026	0.0026
Loa Loa (eye worm)	jmjC domain-containing protein	0.0067	0.0697	0.2711
Entamoeba histolytica	protein tyrosine phosphatase, putative	0.0207	0.257	0.3049
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Entamoeba histolytica	dual specificity protein phosphatase, putative	0.0641	0.837	1
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Trichomonas vaginalis	low molecular weight protein-tyrosine-phosphatase, putative	0.0207	0.257	0.3049
Trichomonas vaginalis	low molecular weight protein tyrosine phosphatase, putative	0.0064	0.0659	0.0759
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Giardia lamblia	Low molecular weight protein-tyrosine-phosphatase	0.0207	0.257	1
Echinococcus multilocularis	receptor type tyrosine protein phosphatase zeta	0.0016	0.0026	0.0026
Brugia malayi	Protein-tyrosine phosphatase	0.0016	0.0026	0.0021
Echinococcus granulosus	Receptor type tyrosine protein phosphatase O	0.0016	0.0026	0.0026
Loa Loa (eye worm)	PHD-finger family protein	0.0032	0.0238	0.0927
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0016	0.0026	0.0103
Schistosoma mansoni	microtubule-associated protein tau	0.0763	1	1
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Brugia malayi	hypothetical protein	0.0016	0.0026	0.0021
Trypanosoma brucei	low molecular weight protein tyrosine phosphatase, putative	0.0064	0.0659	1
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0016	0.0026	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0016	0.0026	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0016	0.0026	0.0103
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0048	0.045	0.045
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0016	0.0026	0.0026
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0141	0.1685	0.1685
Brugia malayi	Protein-tyrosine phosphatase containing protein	0.0016	0.0026	0.0021
Schistosoma mansoni	ap endonuclease	0.0021	0.0086	0.0059
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease	0.0021	0.0086	0.0933
Schistosoma mansoni	hypothetical protein	0.0074	0.0798	0.0773

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Search by CAS
PubChem: 191974

Bibliographic References

No literature references available for this target.

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Detailed information for compound 579039