Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0159 | 0.016 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0927 | 0.1041 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0031 | 0.026 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.0159 | 0.0706 |
Brugia malayi | hypothetical protein | 0.0125 | 0.2235 | 0.2541 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0057 | 0.0813 | 0.2125 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.0019 | 0.0097 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0063 | 0.0927 | 0.1518 |
Loa Loa (eye worm) | hypothetical protein | 0.0172 | 0.3217 | 0.3667 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.0707 | 0.0789 |
Schistosoma mansoni | tar DNA-binding protein | 0.0141 | 0.257 | 0.4268 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0057 | 0.0813 | 0.2125 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0114 | 0.1992 | 0.2262 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.0159 | 0.0706 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0031 | 0.026 | 0.0241 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0057 | 0.0813 | 0.1328 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0363 | 0.0394 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0022 | 0.0003 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0363 | 0.0394 |
Brugia malayi | mbt repeat family protein | 0.005 | 0.0668 | 0.0743 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0157 | 0.2904 | 0.7727 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0437 | 0.874 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0141 | 0.257 | 0.2925 |
Onchocerca volvulus | 0.0063 | 0.0927 | 0.0781 | |
Entamoeba histolytica | phosphofructokinase, putative | 0.0114 | 0.1992 | 1 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0031 | 0.026 | 1 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.005 | 0.0668 | 0.1085 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0159 | 0.016 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0114 | 0.1992 | 0.1976 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.2904 | 0.3308 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0063 | 0.0927 | 0.535 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0063 | 0.0927 | 0.1518 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.005 | 0.0668 | 0.1736 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0031 | 0.026 | 0.2627 |
Loa Loa (eye worm) | phosphofructokinase | 0.0114 | 0.1992 | 0.2262 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0063 | 0.0927 | 0.1518 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0031 | 0.026 | 0.0241 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0159 | 0.0706 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.009 | 0.1507 | 0.3984 |
Loa Loa (eye worm) | mbt repeat family protein | 0.005 | 0.0668 | 0.0743 |
Plasmodium vivax | SET domain protein, putative | 0.0063 | 0.0927 | 1 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0057 | 0.0813 | 0.2125 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0114 | 0.1992 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0026 | 0.0159 | 0.0796 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0022 | 0.0003 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0031 | 0.026 | 1 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0114 | 0.1992 | 0.3301 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.2235 | 0.2541 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0159 | 0.016 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0114 | 0.1992 | 0.5284 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0063 | 0.0927 | 0.2431 |
Brugia malayi | hypothetical protein | 0.0172 | 0.3217 | 0.3667 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0019 | 0.0022 | 0.0014 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0026 | 0.0159 | 0.0706 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0159 | 0.0706 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0063 | 0.0927 | 0.2431 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.0019 | 0.0097 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0114 | 0.1992 | 0.1976 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0707 | 0.0789 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0114 | 0.1992 | 1 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.009 | 0.1507 | 0.3984 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0031 | 0.026 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.0707 | 0.0789 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.009 | 0.1507 | 0.3984 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0159 | 0.0706 |
Onchocerca volvulus | 0.005 | 0.0668 | 0.0517 | |
Onchocerca volvulus | Huntingtin homolog | 0.0125 | 0.2235 | 0.211 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0159 | 0.016 |
Schistosoma mansoni | tar DNA-binding protein | 0.0141 | 0.257 | 0.4268 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.005 | 0.0668 | 0.1736 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0159 | 0.016 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0141 | 0.257 | 0.2925 |
Brugia malayi | Muscleblind-like protein | 0.0157 | 0.2904 | 0.3308 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0114 | 0.1992 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0668 | 0.0743 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.005 | 0.0668 | 0.0517 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0063 | 0.0927 | 0.1518 |
Entamoeba histolytica | pyrophosphate-dependent phosphofructokinase | 0.0031 | 0.026 | 0.1219 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0022 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.2235 | 0.2541 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.0159 | 0.0706 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.009 | 0.1507 | 1 |
Schistosoma mansoni | sex comb on midleg homolog | 0.005 | 0.0668 | 0.1085 |
Loa Loa (eye worm) | cyclic AMP specific phosphodiesterase PDE4D5A | 0.0079 | 0.1277 | 0.1442 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.009 | 0.1507 | 0.2488 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0114 | 0.1992 | 1 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0031 | 0.026 | 0.2627 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0813 | 0.091 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0159 | 0.0706 |
Brugia malayi | phosphofructokinase | 0.0114 | 0.1992 | 0.2262 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0022 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0022 | 0.0003 |
Onchocerca volvulus | Huntingtin homolog | 0.0125 | 0.2235 | 0.211 |
Giardia lamblia | CAMP-specific 3,5-cyclic phosphodiesterase 4B | 0.009 | 0.1507 | 1 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0198 | 0.3752 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0141 | 0.257 | 0.6833 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0079 | 0.1277 | 0.3368 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0114 | 0.1992 | 0.3301 |
Schistosoma mansoni | hypothetical protein | 0.0305 | 0.5996 | 1 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0114 | 0.1992 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0141 | 0.257 | 0.4268 |
Brugia malayi | mbt repeat family protein | 0.005 | 0.0668 | 0.0743 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0114 | 0.1992 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0026 | 0.0159 | 0.016 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0026 | 0.0159 | 0.0796 |
Brugia malayi | 6-phosphofructokinase | 0.0114 | 0.1992 | 0.2262 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.006 | 0.0879 | 0.2302 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0079 | 0.1277 | 0.3368 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.005 | 0.0668 | 0.1736 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0198 | 0.3752 | 1 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0114 | 0.1992 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0497 | 1 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0026 | 0.0159 | 0.0706 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0031 | 0.026 | 0.0241 |
Echinococcus multilocularis | tar DNA binding protein | 0.0141 | 0.257 | 0.6833 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0026 | 0.0159 | 0.0706 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0114 | 0.1992 | 0.5284 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0114 | 0.1992 | 0.2262 |
Schistosoma mansoni | sex comb on midleg homolog | 0.005 | 0.0668 | 0.1085 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.009 | 0.1507 | 0.3984 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.0159 | 0.0706 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0114 | 0.1992 | 1 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.0031 | 0.026 | 0.0241 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.2904 | 0.3308 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0114 | 0.1992 | 1 |
Loa Loa (eye worm) | MBCTL1 | 0.0057 | 0.0813 | 0.091 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0114 | 0.1992 | 0.1976 |
Loa Loa (eye worm) | TAR-binding protein | 0.0141 | 0.257 | 0.2925 |
Brugia malayi | 6-phosphofructokinase | 0.0114 | 0.1992 | 0.2262 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0031 | 0.026 | 0.0241 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0031 | 0.026 | 0.1616 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.005 | 0.0668 | 0.1736 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0031 | 0.026 | 0.0241 |
Echinococcus multilocularis | muscleblind protein | 0.0157 | 0.2904 | 0.7727 |
Schistosoma mansoni | tar DNA-binding protein | 0.0141 | 0.257 | 0.4268 |
Brugia malayi | RNA binding protein | 0.0141 | 0.257 | 0.2925 |
Brugia malayi | Pre-SET motif family protein | 0.0437 | 0.874 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0141 | 0.257 | 0.4268 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0031 | 0.026 | 0.0241 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.0159 | 0.0706 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1507 | 0.1705 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0114 | 0.1992 | 0.1976 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.0079 | 0.1277 | 0.1442 |
Brugia malayi | Pre-SET motif family protein | 0.0063 | 0.0927 | 0.1041 |
Onchocerca volvulus | 0.0172 | 0.3217 | 0.3108 | |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.0022 | 0.0111 |
Echinococcus granulosus | muscleblind protein | 0.0157 | 0.2904 | 0.7727 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0057 | 0.0813 | 0.091 |
Brugia malayi | TAR-binding protein | 0.0141 | 0.257 | 0.2925 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0026 | 0.0159 | 0.0706 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.0707 | 0.0789 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0026 | 0.0159 | 0.0706 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0141 | 0.257 | 0.2925 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0057 | 0.0813 | 0.2125 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0363 | 0.0574 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0063 | 0.0927 | 0.2431 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.