Detailed information for compound 758492

Basic information

Technical information
  • TDR Targets ID: 758492
  • Name: N-(2-bromophenyl)-1-(4-methylphenyl)-2,5-diox o-7,8-dihydro-6H-quinoline-3-carboxamide
  • MW: 451.313 | Formula: C23H19BrN2O3
  • H donors: 1 H acceptors: 3 LogP: 3.88 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(cc1)n1c2CCCC(=O)c2cc(c1=O)C(=O)Nc1ccccc1Br
  • InChi: 1S/C23H19BrN2O3/c1-14-9-11-15(12-10-14)26-20-7-4-8-21(27)16(20)13-17(23(26)29)22(28)25-19-6-3-2-5-18(19)24/h2-3,5-6,9-13H,4,7-8H2,1H3,(H,25,28)
  • InChiKey: UHNQMXOWQIFACZ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(2-bromophenyl)-2,5-diketo-1-(4-methylphenyl)-7,8-dihydro-6H-quinoline-3-carboxamide
  • Oprea1_320166

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0123 0.0123
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0176 0.0176
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0018 0.0414 0.0414
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0006 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0028 0.0747 0.0747
Schistosoma mansoni importin beta-1 0.0028 0.0747 0.0773
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0176 0.0176
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0176 0.0182
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0176 0.0182
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0176 0.0176
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0123 0.0123
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.1865 0.1929
Onchocerca volvulus Sulfhydryl oxidase homolog 0.0018 0.0414 0.1802
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0504 0.029
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.033 0.033
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0113 0.3525 0.3525
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0504 0.029
Echinococcus granulosus geminin 0.0187 0.595 0.595
Brugia malayi hypothetical protein 0.025 0.8016 0.8016
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0504 0.143
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0504 0.5
Brugia malayi hypothetical protein 0.0006 0.0011 0.0011
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0176 0.0176
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0573 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0176 0.0176
Echinococcus granulosus lamin 0.0028 0.076 0.076
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0573 1
Schistosoma mansoni quiescin q6-related sulfhydryl oxidase 0.0018 0.0414 0.0428
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.025 0.8016 0.8016
Schistosoma mansoni hypothetical protein 0.0015 0.033 0.0341
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0176 0.0182
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0043 0.0759
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.1419 0.1419
Leishmania major GTP-binding protein, putative 0.0021 0.0504 0.143
Loa Loa (eye worm) hypothetical protein 0.0011 0.0176 0.0176
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0176 0.0176
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0176 0.0176
Trypanosoma brucei quiescin sulfhydryl oxidase 0.0018 0.0414 0.1174
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0176 0.0176
Echinococcus granulosus GPCR family 2 0.0015 0.033 0.033
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0006 0.0011 0.0011
Brugia malayi quiescin Q6 0.0018 0.0414 0.0414
Echinococcus multilocularis survival motor neuron protein 1 0.025 0.8016 0.8016
Echinococcus multilocularis GPCR, family 2 0.0015 0.033 0.033
Onchocerca volvulus Sulfhydryl oxidase homolog 0.0018 0.0414 0.1802
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0049 0.1419 0.1419
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0326 0.0326
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0176 0.0176
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0176 0.0176
Plasmodium falciparum importin beta, putative 0.0028 0.0747 0.212
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0113 0.3525 1
Brugia malayi nuclear hormone receptor 0.0011 0.0176 0.0176
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0043 0.0759
Entamoeba histolytica hypothetical protein 0.0023 0.0573 1
Schistosoma mansoni lamin 0.0028 0.076 0.0786
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.1419 0.1419
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0176 0.0182
Onchocerca volvulus 0.0028 0.076 0.4422
Loa Loa (eye worm) hypothetical protein 0.0011 0.0176 0.0176
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0176 0.0176
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0176 0.0176
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0504 0.0504
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0573 0.0512
Echinococcus granulosus sulfhydryl oxidase 1 0.0018 0.0414 0.0414
Schistosoma mansoni hypothetical protein 0.03 0.9665 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0043 0.0759
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0504 0.143
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0504 0.143
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0043 0.0759
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0176 0.0182
Schistosoma mansoni hypothetical protein 0.0187 0.595 0.6156
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0176 0.0176
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0043 0.0759
Onchocerca volvulus 0.0029 0.0787 0.4629
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0176 0.0182
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0043 0.0759
Loa Loa (eye worm) hypothetical protein 0.0018 0.0414 0.0414
Loa Loa (eye worm) hypothetical protein 0.0013 0.0259 0.0259
Leishmania major importin beta-1 subunit, putative 0.0023 0.0573 0.1626
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0043 0.0759
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0043 0.0759
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0176 0.0176
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.1647 0.4673
Brugia malayi Nuclear hormone receptor-like 1 0.0006 0.0011 0.0011
Brugia malayi Nuclear hormone receptor-like 1 0.0006 0.0011 0.0011
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0176 0.0182
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0176 0.0176
Schistosoma mansoni cpg binding protein 0.0031 0.0842 0.0871
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0747 0.212
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0747 0.212
Echinococcus granulosus lamin dm0 0.0028 0.076 0.076
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0176 0.0176
Onchocerca volvulus 0.0028 0.076 0.4422
Loa Loa (eye worm) hypothetical protein 0.0011 0.0176 0.0176
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0276 0.0276
Schistosoma mansoni hypothetical protein 0.0187 0.595 0.6156
Brugia malayi CXXC zinc finger family protein 0.0029 0.0787 0.0787
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0018 0.0414 0.1174
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0176 0.0176
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0113 0.3525 1
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0176 0.0182
Echinococcus multilocularis sulfhydryl oxidase 1 0.0018 0.0414 0.0414
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0176 0.0176
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0504 0.0504
Schistosoma mansoni survival motor neuron protein 0.0051 0.1496 0.1548
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0176 0.0176
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0176 0.0176
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.033 0.033
Loa Loa (eye worm) hypothetical protein 0.0013 0.0259 0.0259
Echinococcus multilocularis musashi 0.0028 0.076 0.076
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0176 0.0176
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0176 0.0176
Toxoplasma gondii Erv1 / Alr family protein 0.0018 0.0414 0.1174
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.076 0.076
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0043 0.0759
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0007 0.0065 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0043 0.0759
Loa Loa (eye worm) Erv1/Alr family protein 0.0018 0.0414 0.0414
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0573 1
Onchocerca volvulus Sulfhydryl oxidase homolog 0.0018 0.0414 0.1802
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0113 0.3525 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0033 0.0915 0.0915
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0011 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0028 0.0743 0.0743
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0504 0.0504
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0176 0.0176
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.033 0.033
Loa Loa (eye worm) hypothetical protein 0.0006 0.0011 0.0011
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0006 0.0011 0.0011
Trichomonas vaginalis helicase, putative 0.0007 0.0043 0.0759
Echinococcus multilocularis lamin 0.0028 0.076 0.076
Brugia malayi intermediate filament protein 0.0028 0.076 0.076
Schistosoma mansoni hypothetical protein 0.0015 0.033 0.0341
Schistosoma mansoni coup transcription factor 0.0011 0.0176 0.0182
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0043 0.0759
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0326 0.0326
Plasmodium vivax hypothetical protein, conserved 0.0018 0.0414 0.1174
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0051 0.1496 0.1496
Echinococcus granulosus snurportin 1 0.03 0.9665 0.9665
Brugia malayi nuclear receptor RXR 0.0006 0.0011 0.0011
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.033 0.033
Loa Loa (eye worm) hypothetical protein 0.0014 0.0276 0.0276
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0176 0.0176
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0176 0.0176
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0006 0.0011 0.0011
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0176 0.0176
Echinococcus multilocularis lamin dm0 0.0028 0.076 0.076
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.033 0.033
Echinococcus granulosus importin subunit beta 1 0.0028 0.0747 0.0747
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0043 0.0759
Loa Loa (eye worm) hypothetical protein 0.0028 0.076 0.076
Schistosoma mansoni lamin 0.0028 0.076 0.0786
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.076 0.076
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0043 0.0759
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0007 0.0065 0.0065
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0176 0.0176
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0113 0.3525 1
Echinococcus multilocularis cpg binding protein 0.0031 0.0842 0.0842
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0176 0.0176
Schistosoma mansoni cpg binding protein 0.0031 0.0842 0.0871
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0113 0.3525 1
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0747 0.0747
Echinococcus multilocularis muscleblind protein 1 0.031 1 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0176 0.0176
Plasmodium vivax importin-beta 2, putative 0.0028 0.0747 0.212
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0043 0.0759
Loa Loa (eye worm) hepatopoietin HPO2 0.0113 0.3525 0.3525
Schistosoma mansoni hypothetical protein 0.0033 0.0915 0.0947
Brugia malayi Augmenter of liver regeneration 0.0113 0.3525 0.3525
Loa Loa (eye worm) hypothetical protein 0.0011 0.0176 0.0176
Brugia malayi Importin beta-1 subunit 0.0028 0.0747 0.0747
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.1419 0.1419
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0065 0.0067
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0113 0.3525 0.3525
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0176 0.0176
Trichomonas vaginalis ran, putative 0.0021 0.0504 0.8795
Schistosoma mansoni hypothetical protein 0.0015 0.033 0.0341
Schistosoma mansoni cpg binding protein 0.0029 0.0787 0.0814
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0747 0.212
Loa Loa (eye worm) hypothetical protein 0.0006 0.0011 0.0011
Leishmania major hypothetical protein, conserved 0.0113 0.3525 1
Echinococcus granulosus survival motor neuron protein 1 0.025 0.8016 0.8016
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0176 0.0182
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0276 0.0276
Brugia malayi hypothetical protein 0.0006 0.0011 0.0011
Toxoplasma gondii Erv1 / Alr family protein 0.0113 0.3525 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0176 0.0176
Toxoplasma gondii Erv1 / Alr family protein 0.0113 0.3525 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0176 0.0182
Loa Loa (eye worm) hypothetical protein 0.0011 0.0176 0.0176
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0176 0.0176
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0787 0.0787
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0007 0.0065 0.0065
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0006 0.0011 0.0011
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0176 0.0182
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0176 0.0182
Schistosoma mansoni ran 0.0021 0.0504 0.0521
Loa Loa (eye worm) hypothetical protein 0.0006 0.0011 0.0011
Brugia malayi steroid hormone receptor 0.0011 0.0176 0.0176
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0043 0.0759
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0043 0.0759
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0176 0.0176
Brugia malayi Latrophilin receptor protein 2 0.0015 0.033 0.033
Loa Loa (eye worm) hypothetical protein 0.0011 0.0176 0.0176
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.033 0.033
Brugia malayi nuclear receptor NHR-88 0.0011 0.0176 0.0176
Echinococcus granulosus intermediate filament protein 0.0028 0.076 0.076
Loa Loa (eye worm) hypothetical protein 0.031 1 1
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0119 0.0119
Echinococcus granulosus muscleblind protein 0.031 1 1
Echinococcus multilocularis snurportin 1 0.03 0.9665 0.9665
Loa Loa (eye worm) quiescin Q6 0.0018 0.0414 0.0414
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0176 0.0176
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0123 0.0123
Brugia malayi Erv1 / Alr family protein 0.0018 0.0414 0.0414
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.03 0.9665 0.9665
Loa Loa (eye worm) hypothetical protein 0.0006 0.0011 0.0011
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0006 0.0011 0.0011
Schistosoma mansoni hypothetical protein 0.0015 0.033 0.0341
Loa Loa (eye worm) hypothetical protein 0.0015 0.033 0.033
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0043 0.0759
Loa Loa (eye worm) hypothetical protein 0.0011 0.0176 0.0176
Echinococcus multilocularis geminin 0.0187 0.595 0.595
Schistosoma mansoni ran 0.0021 0.0504 0.0521
Onchocerca volvulus 0.0051 0.1496 1
Echinococcus multilocularis muscleblind protein 0.031 1 1
Echinococcus granulosus cpg binding protein 0.0031 0.0842 0.0842
Loa Loa (eye worm) intermediate filament protein 0.0028 0.076 0.076
Echinococcus granulosus mixed lineage leukemia protein mll 0.0007 0.0065 0.0065
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0504 0.143
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0176 0.0176
Entamoeba histolytica Ran family GTPase 0.0021 0.0504 0.8795
Brugia malayi RNA, U transporter 1 0.008 0.2447 0.2447
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0176 0.0176
Schistosoma mansoni intermediate filament proteins 0.0028 0.076 0.0786
Brugia malayi ecdysteroid receptor 0.0011 0.0176 0.0176
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0915 0.0915
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0113 0.3525 1
Schistosoma mansoni hypothetical protein 0.0051 0.1496 0.1548
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0504 0.0504
Loa Loa (eye worm) hypothetical protein 0.031 1 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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