TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 332.441 | Formula: C18H28N4O2
H donors: 1 H acceptors: 3 LogP: 2.29 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: OCCC1CN(CCN1CC(C)(C)C)Cc1cccc2c1non2
InChi: 1S/C18H28N4O2/c1-18(2,3)13-22-9-8-21(12-15(22)7-10-23)11-14-5-4-6-16-17(14)20-24-19-16/h4-6,15,23H,7-13H2,1-3H3
InChiKey: SQUUDQZDIYTEHO-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	dro:myosuppressin receptor	0.0013	0.0005	0.0011
Trichomonas vaginalis	conserved hypothetical protein	0.0217	0.2253	1
Brugia malayi	hypothetical protein	0.0013	0.0005	0.0024
Mycobacterium leprae	Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase)	0.0041	0.0318	0.5469
Brugia malayi	Major Facilitator Superfamily protein	0.0031	0.0201	0.0894
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Mycobacterium tuberculosis	Probable hydrolase	0.0035	0.0249	0.1076
Plasmodium falciparum	calcium-dependent protein kinase 3	0.0067	0.0597	0.0597
Echinococcus granulosus	General substrate transporter	0.0187	0.1918	0.3908
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Plasmodium falciparum	hexose transporter	0.0217	0.2253	0.2253
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0372	0.1651
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0201	0.0894
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0013	0.0005	0.0011
Mycobacterium tuberculosis	Lysyl-tRNA synthetase 2 LysX	0.0041	0.0318	0.1374
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0013	0.0005	0.0011
Leishmania major	lysyl-tRNA synthetase, putative	0.0048	0.0399	0.5689
Schistosoma mansoni	neuropeptide F-like receptor	0.0013	0.0005	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Onchocerca volvulus		0.0031	0.0201	0.1335
Trichomonas vaginalis	D-aminoacylase, putative	0.0035	0.0249	0.1106
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0013	0.0005	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0201	0.0894
Echinococcus granulosus	neuropeptide Y receptor	0.0013	0.0005	0.0011
Trypanosoma brucei	apurinic/apyrimidinic endonuclease, putative	0.0018	0.0066	0.0939
Toxoplasma gondii	protein kinase, putative	0.0613	0.6612	1
Echinococcus multilocularis	g-protein coupled receptor	0.0013	0.0005	0.0011
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0013	0.0005	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Trypanosoma cruzi	prolyl-tRNA synthetase, putative	0.0076	0.0701	1
Trypanosoma brucei	hypothetical protein, conserved	0.0035	0.0249	0.3558
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Schistosoma mansoni	neuropeptide receptor	0.0013	0.0005	0.0024
Chlamydia trachomatis	proline--tRNA ligase	0.0023	0.0119	0.2978
Echinococcus granulosus	rhodopsin orphan GPCR	0.0013	0.0005	0.0011
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0013	0.0005	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0201	0.0894
Echinococcus multilocularis	solute carrier family 22	0.0031	0.0201	0.041
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0217	0.2253	0.4592
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0046	0.0372	0.1651
Mycobacterium ulcerans	prolyl-tRNA synthetase	0.0023	0.0119	0.2978
Trypanosoma cruzi	hexose transporter, putative	0.0067	0.0606	0.8651
Toxoplasma gondii	prolyl-tRNA synthetase (ProRS)	0.0076	0.0701	0.106
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Schistosoma mansoni	neuropeptide F-like receptor	0.0013	0.0005	0.0024
Entamoeba histolytica	protein kinase, putative	0.0066	0.0597	1
Trypanosoma cruzi	sugar transporter, putative	0.0031	0.0201	0.2874
Echinococcus granulosus	rhodopsin orphan GPCR	0.0013	0.0005	0.0011
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Echinococcus granulosus	tm gpcr rhodopsin	0.0013	0.0005	0.0011
Onchocerca volvulus		0.0146	0.1474	1
Echinococcus granulosus	somatostatin receptor	0.0013	0.0005	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0399	0.1769
Brugia malayi	AKH receptor	0.0013	0.0005	0.0024
Onchocerca volvulus		0.0031	0.0201	0.1335
Trichomonas vaginalis	lysyl-tRNA synthetase, putative	0.0048	0.0399	0.1769
Echinococcus granulosus	g-protein coupled receptor	0.0013	0.0005	0.0011
Mycobacterium ulcerans	sugar transporter	0.0031	0.0201	0.5052
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Leishmania major	protein kinase, putative	0.0066	0.0597	0.8517
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Brugia malayi	G-protein coupled receptor	0.0013	0.0005	0.0024
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0013	0.0005	0.0011
Echinococcus granulosus	orexin receptor type 2	0.0013	0.0005	0.0011
Echinococcus granulosus	solute carrier family 22	0.0031	0.0201	0.041
Trichomonas vaginalis	conserved hypothetical protein	0.0031	0.0201	0.0894
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0223	0.2317	1
Echinococcus multilocularis	g protein coupled receptor	0.0013	0.0005	0.0011
Schistosoma mansoni	opsin-like receptor	0.0013	0.0005	0.0024
Trichomonas vaginalis	glucose transporter, putative	0.0067	0.0606	0.269
Schistosoma mansoni	neuropeptide f receptor 76f	0.0013	0.0005	0.0024
Toxoplasma gondii	sugar transporter ST1	0.0031	0.0201	0.0305
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0217	0.2253	0.4592
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0201	0.0894
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Echinococcus granulosus	allatostatin A receptor	0.0013	0.0005	0.0011
Echinococcus granulosus	hypothetical protein	0.0013	0.0005	0.0011
Brugia malayi	hypothetical protein	0.0031	0.0201	0.0894
Trypanosoma brucei	glucose transporter, putative	0.0067	0.0606	0.8651
Brugia malayi	hypothetical protein	0.0013	0.0005	0.0024
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0013	0.0005	0.0024
Echinococcus granulosus	7tm_1 domain containing protein	0.0013	0.0005	0.0011
Trichomonas vaginalis	myo-inositol transporter, putative	0.0031	0.0201	0.0894
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0066	0.0597	0.1216
Plasmodium falciparum	calcium-dependent protein kinase 5	0.0067	0.0597	0.0597
Onchocerca volvulus		0.0031	0.0201	0.1335
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0201	0.0894
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0249	0.1106
Brugia malayi	hypothetical protein	0.0013	0.0005	0.0024
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Echinococcus granulosus	neuropeptide receptor A26	0.0458	0.4907	1
Echinococcus multilocularis	g protein coupled receptor	0.0013	0.0005	0.0011
Echinococcus multilocularis	neuropeptides capa receptor	0.0013	0.0005	0.0011
Toxoplasma gondii	ABC1 family protein	0.0035	0.0249	0.0377
Onchocerca volvulus		0.0035	0.0249	0.1661
Echinococcus multilocularis	neuropeptide receptor	0.0013	0.0005	0.0011
Wolbachia endosymbiont of Brugia malayi	exonuclease III	0.0018	0.0066	0.3266
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0013	0.0005	0.0011
Mycobacterium ulcerans	lysyl-tRNA synthetase	0.0048	0.0399	1
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0217	0.2253	0.4592
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0066	0.0597	0.1216
Mycobacterium tuberculosis	Possible conserved lipoprotein LpqK	0.0035	0.0249	0.1076
Brugia malayi	putative neuropeptide receptor	0.0013	0.0005	0.0024
Schistosoma mansoni	glucose transport protein	0.0217	0.2253	1
Echinococcus multilocularis	synaptic vesicle 2 protein	0.0031	0.0201	0.041
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Plasmodium falciparum	calcium-dependent protein kinase 4	0.0067	0.0597	0.0597
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0013	0.0005	0.0024
Echinococcus multilocularis	serotonin receptor	0.0013	0.0005	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type 1	0.0066	0.0597	0.1216
Mycobacterium leprae	Probable prolyl tRNA synthetase ProS	0.0065	0.0582	1
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Brugia malayi	hypothetical protein	0.0013	0.0005	0.0024
Mycobacterium tuberculosis	Probable conserved lipoprotein	0.0035	0.0249	0.1076
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0013	0.0005	0.0024
Echinococcus granulosus	G protein coupled receptor 139	0.0013	0.0005	0.0011
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0013	0.0005	0.0024
Schistosoma mansoni	lysyl-tRNA synthetase	0.0048	0.0399	0.1769
Schistosoma mansoni	neuropeptide receptor	0.0013	0.0005	0.0024
Trichomonas vaginalis	CAMK family protein kinase	0.0066	0.0597	0.2648
Schistosoma mansoni	glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs)	0.0065	0.0582	0.2583
Onchocerca volvulus		0.0031	0.0201	0.1335
Echinococcus granulosus	neuropeptide receptor	0.0013	0.0005	0.0011
Echinococcus multilocularis	serotonin receptor	0.0013	0.0005	0.0011
Schistosoma mansoni	ap endonuclease	0.0018	0.0066	0.0292
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0013	0.0005	0.0011
Mycobacterium tuberculosis	Conserved protein	0.0035	0.0249	0.1076
Giardia lamblia	Prolyl-tRNA synthetase	0.0065	0.0582	1
Leishmania major	apurinic/apyrimidinic endonuclease-redox protein	0.0018	0.0066	0.0939
Onchocerca volvulus		0.0031	0.0201	0.1335
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0013	0.0005	0.0024
Trichomonas vaginalis	glucose transporter, putative	0.0067	0.0606	0.269
Toxoplasma gondii	calcium-dependent protein kinase CDPK2B	0.0067	0.0597	0.0903
Onchocerca volvulus		0.0031	0.0201	0.1335
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Giardia lamblia	Endonuclease/Exonuclease/phosphatase	0.0018	0.0066	0.113
Brugia malayi	Major Facilitator Superfamily protein	0.0031	0.0201	0.0894
Brugia malayi	hypothetical protein	0.0146	0.1474	0.6539
Mycobacterium tuberculosis	Probable esterase/lipase LipP	0.0035	0.0249	0.1076
Onchocerca volvulus		0.0031	0.0201	0.1335
Toxoplasma gondii	transporter, major facilitator family protein	0.0031	0.0201	0.0305
Trypanosoma brucei	glucose transporter, putative	0.0067	0.0606	0.8651
Schistosoma mansoni	hypothetical protein	0.0013	0.0005	0.0024
Leishmania major	prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative	0.0076	0.0701	1
Plasmodium falciparum	protein kinase 7	0.0613	0.6612	0.6612
Toxoplasma gondii	cell-cycle-associated protein kinase MAPK, putative	0.0351	0.3724	0.5632
Trichomonas vaginalis	conserved hypothetical protein	0.0067	0.0606	0.269
Brugia malayi	hypothetical protein	0.0013	0.0005	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0065	0.0582	0.2583
Plasmodium vivax	calcium-dependent protein kinase 4, putative	0.0067	0.0597	0.0597
Mycobacterium ulcerans	sugar-transport integral membrane protein SugI	0.0031	0.0201	0.5052
Echinococcus granulosus	neuropeptide receptor	0.0013	0.0005	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Giardia lamblia	Lysyl-tRNA synthetase	0.0048	0.0399	0.6849
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0013	0.0005	0.0024
Schistosoma mansoni	amine GPCR	0.0013	0.0005	0.0024
Schistosoma mansoni	histamine h1 receptor	0.0013	0.0005	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Toxoplasma gondii	lysine-tRNA ligase	0.0048	0.0399	0.0603
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Trichomonas vaginalis	sugar transporter, putative	0.0067	0.0606	0.269
Echinococcus granulosus	solute carrier family 22	0.0031	0.0201	0.041
Brugia malayi	beta-lactamase	0.0035	0.0249	0.1106
Schistosoma mansoni	hypothetical protein	0.0013	0.0005	0.0024
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0035	0.0249	0.1106
Plasmodium falciparum	calcium-dependent protein kinase 1	0.0067	0.0597	0.0597
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Echinococcus granulosus	g protein coupled receptor	0.0013	0.0005	0.0011
Schistosoma mansoni	opsin-like receptor	0.0013	0.0005	0.0024
Toxoplasma gondii	sugar transporter ST2	0.0031	0.0201	0.0305
Brugia malayi	hypothetical protein	0.0013	0.0005	0.0024
Leishmania major	glucose transporter, lmgt3	0.0067	0.0606	0.8651
Brugia malayi	Serotonin receptor	0.0013	0.0005	0.0024
Trypanosoma cruzi	hexose transporter, putative	0.0037	0.027	0.386
Brugia malayi	hypothetical protein	0.0031	0.0201	0.0894
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Brugia malayi	G protein-coupled receptor F59B2.13	0.0013	0.0005	0.0024
Treponema pallidum	exodeoxyribonuclease (exoA)	0.0018	0.0066	0.5542
Entamoeba histolytica	exodeoxyribonuclease III, putative	0.0018	0.0066	0.1102
Echinococcus multilocularis	neuropeptide receptor A26	0.0458	0.4907	1
Plasmodium vivax	proline--tRNA ligase, putative	0.0076	0.0701	0.0701
Brugia malayi	Serotonin receptor	0.0013	0.0005	0.0024
Mycobacterium ulcerans	integral membrane transport protein	0.0031	0.0201	0.5052
Onchocerca volvulus		0.0031	0.0201	0.1335
Echinococcus granulosus	biogenic amine 5HT receptor	0.0013	0.0005	0.0011
Echinococcus granulosus	solute carrier family 22	0.0031	0.0201	0.041
Trypanosoma brucei	glucose transporter, putative	0.0067	0.0606	0.8651
Onchocerca volvulus		0.0035	0.0249	0.1661
Trichomonas vaginalis	prolyl-tRNA synthetase, putative	0.0065	0.0582	0.2583
Brugia malayi	Sugar transporter family protein	0.0031	0.0201	0.0894
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0013	0.0005	0.0024
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Mycobacterium tuberculosis	Probable lipase LipD	0.0035	0.0249	0.1076
Echinococcus granulosus	geminin	0.0164	0.1669	0.3401
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0372	0.1651
Schistosoma mansoni	ap endonuclease	0.0018	0.0066	0.0292
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0013	0.0005	0.0024
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0067	0.0606	0.8651
Echinococcus multilocularis	solute carrier family 22	0.0031	0.0201	0.041
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0217	0.2253	0.4592
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	0.0018	0.0066	0.0134
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Brugia malayi	Calcium/calmodulin-dependent protein kinase type II alpha chain	0.0066	0.0597	0.2648
Echinococcus multilocularis	g protein coupled receptor	0.0013	0.0005	0.0011
Schistosoma mansoni	protein kinase	0.0066	0.0597	0.2648
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Schistosoma mansoni	protein kinase	0.0066	0.0597	0.2648
Toxoplasma gondii	calcium-dependent protein kinase CDPK3	0.0067	0.0597	0.0903
Echinococcus multilocularis	General substrate transporter	0.0187	0.1918	0.3908
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0013	0.0005	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0065	0.0582	0.2583
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0013	0.0005	0.0011
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0013	0.0005	0.0024
Echinococcus granulosus	synaptic vesicle 2 protein	0.0031	0.0201	0.041
Plasmodium falciparum	lysine--tRNA ligase	0.0048	0.0399	0.0399
Brugia malayi	putative neuropeptide receptor NPR1	0.0013	0.0005	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0201	0.0894
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0013	0.0005	0.0011
Schistosoma mansoni	sugar transporter	0.0031	0.0201	0.0894
Trypanosoma brucei	lysyl-tRNA synthetase, putative	0.0048	0.0399	0.5689
Schistosoma mansoni	hypothetical protein	0.0164	0.1669	0.7405
Schistosoma mansoni	amine GPCR	0.0013	0.0005	0.0024
Trypanosoma brucei	bifunctional aminoacyl-tRNA synthetase, putative	0.0076	0.0701	1
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0035	0.0249	0.1106
Echinococcus multilocularis	Sugar transporter ERD6 protein	0.0031	0.0201	0.041
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Brugia malayi	Major Facilitator Superfamily protein	0.0031	0.0201	0.0894
Brugia malayi	Bifunctional aminoacyl-tRNA synthetase	0.0065	0.0582	0.2583
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0067	0.0606	0.8651
Schistosoma mansoni	hypothetical protein	0.0013	0.0005	0.0024
Trypanosoma brucei	glucose transporter, putative	0.0067	0.0606	0.8651
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0249	0.1106
Loa Loa (eye worm)	bifunctional aminoacyl-tRNA synthetase	0.0027	0.016	0.0709
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0249	0.1106
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Echinococcus multilocularis	neuropeptide Y receptor	0.0013	0.0005	0.0011
Brugia malayi	Sugar transporter family protein	0.0217	0.2253	1
Trichomonas vaginalis	sugar transporter, putative	0.0067	0.0606	0.269
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0013	0.0005	0.0011
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Trichomonas vaginalis	sugar transporter, putative	0.0067	0.0606	0.269
Mycobacterium ulcerans	hypothetical protein	0.0035	0.0249	0.6253
Echinococcus granulosus	neuropeptide Y receptor	0.0013	0.0005	0.0011
Schistosoma mansoni	sugar transporter	0.0031	0.0201	0.0894
Mycobacterium tuberculosis	Probable conserved integral membrane transport protein	0.0031	0.0201	0.0869
Loa Loa (eye worm)	beta-lactamase	0.0035	0.0249	0.1106
Echinococcus multilocularis	sex peptide receptor	0.0013	0.0005	0.0011
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0013	0.0005	0.0024
Brugia malayi	GnHR receptor homolog	0.0013	0.0005	0.0024
Trichomonas vaginalis	sugar transport protein, putative	0.0031	0.0201	0.0894
Trypanosoma brucei	glucose transporter, putative	0.0067	0.0606	0.8651
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Echinococcus multilocularis	fmrfamide receptor	0.0013	0.0005	0.0011
Onchocerca volvulus		0.0031	0.0201	0.1335
Schistosoma mansoni	adenoreceptor	0.0013	0.0005	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0201	0.0894
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0201	0.0894
Trichomonas vaginalis	glucose transporter, putative	0.0031	0.0201	0.0894
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0013	0.0005	0.0011
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0013	0.0005	0.0024
Trichomonas vaginalis	D-aminoacylase, putative	0.0035	0.0249	0.1106
Brugia malayi	Dopamine receptor protein 1	0.0013	0.0005	0.0024
Onchocerca volvulus		0.0031	0.0201	0.1335
Trypanosoma brucei	calcium/calmodulin-dependent protein kinase, putative	0.0066	0.0597	0.8517
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Brugia malayi	hypothetical protein	0.0013	0.0005	0.0024
Mycobacterium leprae	conserved hypothetical protein	0.0035	0.0249	0.4283
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0217	0.2253	0.4592
Schistosoma mansoni	amine GPCR	0.0013	0.0005	0.0024
Trypanosoma cruzi	hexose transporter, putative	0.0067	0.0606	0.8651
Brugia malayi	neuropeptide F receptor	0.0013	0.0005	0.0024
Mycobacterium ulcerans	esterase/lipase LipP	0.0035	0.0249	0.6253
Onchocerca volvulus		0.0031	0.0201	0.1335
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0013	0.0005	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0201	0.0894
Trichomonas vaginalis	lysyl-tRNA synthetase, putative	0.0042	0.0333	0.1477
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Trypanosoma brucei	glucose transporter 2A	0.0067	0.0606	0.8651
Mycobacterium tuberculosis	Probable esterase LipL	0.0035	0.0249	0.1076
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Brugia malayi	beta-lactamase family protein	0.0035	0.0249	0.1106
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Plasmodium vivax	sugar transporter, putative	0.0031	0.0201	0.0201
Brugia malayi	larval opioid receptor	0.0013	0.0005	0.0024
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Schistosoma mansoni	serine/threonine protein kinase	0.0066	0.0597	0.2648
Loa Loa (eye worm)	G-protein coupled receptor	0.0013	0.0005	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0249	0.1106
Plasmodium vivax	mitogen-activated protein kinase 2, putative	0.0351	0.3724	0.3724
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0066	0.0597	0.1216
Schistosoma mansoni	nuclear transcription factor X-box binding 1 (nfx1)	0.0031	0.0201	0.0894
Echinococcus granulosus	neuropeptide s receptor	0.0458	0.4907	1
Brugia malayi	Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative	0.0035	0.0249	0.1106
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0013	0.0005	0.0011
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0013	0.0005	0.0011
Echinococcus granulosus	rhodopsin orphan GPCR	0.0013	0.0005	0.0011
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0013	0.0005	0.0024
Brugia malayi	hypothetical protein	0.0013	0.0005	0.0024
Plasmodium falciparum	major facilitator superfamily domain-containing protein, putative	0.0031	0.0201	0.0201
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Echinococcus granulosus	lysyl tRNA synthetase	0.0048	0.0399	0.0812
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0013	0.0005	0.0011
Mycobacterium tuberculosis	Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter)	0.0031	0.0201	0.0869
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0013	0.0005	0.0011
Echinococcus multilocularis	neuropeptide receptor	0.0013	0.0005	0.0011
Trypanosoma brucei	THT1 - hexose transporter, putative	0.0067	0.0606	0.8651
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease	0.0018	0.0066	0.0939
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Brugia malayi	Dopamine receptor protein 2	0.0013	0.0005	0.0024
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	0.0018	0.0066	0.0292
Trypanosoma cruzi	hexose transporter, putative	0.0067	0.0606	0.8651
Mycobacterium ulcerans	exodeoxyribonuclease III protein XthA	0.0018	0.0066	0.165
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0013	0.0005	0.0011
Schistosoma mansoni	hypothetical protein	0.0013	0.0005	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Brugia malayi	Melatonin receptor type 1A	0.0013	0.0005	0.0024
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0372	0.1651
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0013	0.0005	0.0024
Leishmania major	hypothetical protein, conserved	0.0031	0.0201	0.2874
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0013	0.0005	0.0024
Trypanosoma brucei	myo-inositol/proton symporter (MIT)	0.0031	0.0201	0.2874
Trypanosoma brucei	glucose transporter, putative	0.0067	0.0606	0.8651
Echinococcus multilocularis	G protein coupled receptor 139	0.0013	0.0005	0.0011
Echinococcus granulosus	serotonin receptor	0.0013	0.0005	0.0011
Mycobacterium tuberculosis	Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI)	0.0018	0.0066	0.0284
Echinococcus multilocularis	neuropeptide s receptor	0.0458	0.4907	1
Trypanosoma brucei	glucose transporter, putative	0.0067	0.0606	0.8651
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0013	0.0005	0.0011
Toxoplasma gondii	sugar transporter ST3	0.0031	0.0201	0.0305
Giardia lamblia	Hexose transporter	0.0031	0.0201	0.346
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Mycobacterium ulcerans	lysyl-tRNA synthetase	0.0048	0.0399	1
Loa Loa (eye worm)	beta-LACTamase domain containing family member	0.0035	0.0249	0.1106
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0013	0.0005	0.0024
Leishmania major	glucose transporter, lmgt2	0.0067	0.0606	0.8651
Brugia malayi	RE15519p	0.0013	0.0005	0.0024
Plasmodium vivax	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0018	0.0066	0.0066
Echinococcus multilocularis	geminin	0.0164	0.1669	0.3401
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0249	0.1106
Echinococcus granulosus	neuropeptides capa receptor	0.0013	0.0005	0.0011
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0013	0.0005	0.0024
Mycobacterium ulcerans	lipase LipD	0.0035	0.0249	0.6253
Plasmodium vivax	calcium-dependent protein kinase, putative	0.0067	0.0597	0.0597
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0146	0.1474	0.6539
Echinococcus granulosus	calcium dependent protein kinase	0.0062	0.0552	0.1124
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0013	0.0005	0.0024
Loa Loa (eye worm)	melatonin receptor type 1A	0.0013	0.0005	0.0024
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0013	0.0005	0.0024
Plasmodium vivax	lysine--tRNA ligase, putative	0.0048	0.0399	0.0399
Trichomonas vaginalis	conserved hypothetical protein	0.0031	0.0201	0.0894
Brugia malayi	exodeoxyribonuclease III family protein	0.0018	0.0066	0.0292
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Trichomonas vaginalis	conserved hypothetical protein	0.0031	0.0201	0.0894
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0013	0.0005	0.0011
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	0.0018	0.0066	0.0134
Trypanosoma cruzi	hypothetical protein, conserved	0.0035	0.0249	0.3558
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Schistosoma mansoni	glucose transport protein	0.0217	0.2253	1
Trichomonas vaginalis	D-aminoacylase, putative	0.0035	0.0249	0.1106
Plasmodium vivax	CDK-related protein kinase 6, putative	0.0921	1	1
Echinococcus granulosus	neuropeptide FF receptor 2	0.0013	0.0005	0.0011
Loa Loa (eye worm)	neuropeptide F receptor	0.0013	0.0005	0.0024
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0013	0.0005	0.0024
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Echinococcus granulosus	solute carrier family 2 facilitated glucose	0.0217	0.2253	0.4592
Onchocerca volvulus		0.0031	0.0201	0.1335
Echinococcus granulosus	rhodopsin orphan GPCR	0.0013	0.0005	0.0011
Echinococcus granulosus	neuropeptides capa receptor	0.0013	0.0005	0.0011
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Echinococcus multilocularis	solute carrier family 2 facilitated glucose	0.0217	0.2253	0.4592
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0201	0.0894
Mycobacterium ulcerans	beta-lactamase	0.0035	0.0249	0.6253
Leishmania major	myo-inositol/proton symporter (MIT)	0.0031	0.0201	0.2874
Plasmodium falciparum	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0018	0.0066	0.0066
Leishmania major	glucose transporter, lmgt1	0.0067	0.0606	0.8651
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0046	0.0372	0.0758
Schistosoma mansoni	amine GPCR	0.0013	0.0005	0.0024
Echinococcus multilocularis	orexin receptor type 2	0.0013	0.0005	0.0011
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0013	0.0005	0.0024
Loa Loa (eye worm)	sugar transporter	0.0031	0.0201	0.0894
Onchocerca volvulus		0.0035	0.0249	0.1661
Loa Loa (eye worm)	major facilitator superfamily transporter	0.0031	0.0201	0.0894
Trichomonas vaginalis	ap endonuclease, putative	0.0018	0.0066	0.0292
Echinococcus granulosus	Sugar transporter ERD6 protein	0.0031	0.0201	0.041
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0013	0.0005	0.0024
Schistosoma mansoni	biogenic amine receptor	0.0013	0.0005	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Schistosoma mansoni	opsin-like receptor	0.0013	0.0005	0.0024
Echinococcus multilocularis	dro:myosuppressin receptor	0.0013	0.0005	0.0011
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Onchocerca volvulus		0.0031	0.0201	0.1335
Trichomonas vaginalis	esterase, putative	0.0035	0.0249	0.1106
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0249	0.1106
Loa Loa (eye worm)	G-protein coupled receptor	0.0013	0.0005	0.0024
Echinococcus granulosus	beta LACTamase domain containing family member	0.0035	0.0249	0.0508
Onchocerca volvulus		0.0031	0.0201	0.1335
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0066	0.0597	0.1216
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Entamoeba histolytica	protein kinase, putative	0.0066	0.0597	1
Echinococcus multilocularis	neuropeptide Y receptor	0.0013	0.0005	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0201	0.0894
Trichomonas vaginalis	penicillin-binding protein, putative	0.0035	0.0249	0.1106
Plasmodium falciparum	calcium-dependent protein kinase 2	0.0067	0.0597	0.0597
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0013	0.0005	0.0024
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0013	0.0005	0.0024
Entamoeba histolytica	hypothetical protein	0.0048	0.0399	0.6679
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0201	0.0894
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0201	0.0894
Mycobacterium tuberculosis	Conserved protein	0.0035	0.0249	0.1076
Schistosoma mansoni	neuropeptide receptor	0.0013	0.0005	0.0024
Brugia malayi	beta-lactamase family protein	0.0035	0.0249	0.1106
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0046	0.0372	0.0758
Trypanosoma brucei	glucose transporter 1E	0.0067	0.0606	0.8651
Plasmodium vivax	hypothetical protein, conserved	0.0035	0.0249	0.0249
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	0.0018	0.0066	0.0939
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0013	0.0005	0.0011
Echinococcus granulosus	solute carrier family 22	0.0031	0.0201	0.041
Toxoplasma gondii	calcium-dependent protein kinase CDPK2A	0.0067	0.0597	0.0903
Mycobacterium ulcerans	fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT	0.0031	0.0201	0.5052
Trypanosoma cruzi	prolyl-tRNA synthetase, putative	0.0076	0.0701	1
Plasmodium falciparum	mitogen-activated protein kinase 2	0.0351	0.3724	0.3724
Echinococcus multilocularis	solute carrier family 2, facilitated glucose	0.0217	0.2253	0.4592
Trypanosoma cruzi	hypothetical protein, conserved	0.0035	0.0249	0.3558
Schistosoma mansoni	biogenic amine receptor	0.0013	0.0005	0.0024
Brugia malayi	major facilitator superfamily protein	0.0031	0.0201	0.0894
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0013	0.0005	0.0011
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Plasmodium vivax	hexose transporter	0.0217	0.2253	0.2253
Toxoplasma gondii	exonuclease III APE	0.0018	0.0066	0.0099
Echinococcus granulosus	fmrfamide receptor	0.0013	0.0005	0.0011
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Mycobacterium tuberculosis	Conserved protein	0.0035	0.0249	0.1076
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0013	0.0005	0.0024
Echinococcus granulosus	biogenic amine 5HT receptor	0.0013	0.0005	0.0011
Trypanosoma brucei	sugar transporter, putative	0.0031	0.0201	0.2874
Schistosoma mansoni	sugar transporter	0.0031	0.0201	0.0894
Loa Loa (eye worm)	neuropeptide F receptor	0.0013	0.0005	0.0024
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0013	0.0005	0.0011
Schistosoma mansoni	hypothetical protein	0.0164	0.1669	0.7405
Echinococcus multilocularis	somatostatin receptor	0.0013	0.0005	0.0011
Chlamydia trachomatis	lysine--tRNA ligase	0.0048	0.0399	1
Loa Loa (eye worm)	sugar transporter	0.0217	0.2253	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0013	0.0005	0.0011
Loa Loa (eye worm)	calcium/calmodulin-dependent protein kinase ID	0.0066	0.0597	0.2648
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0013	0.0005	0.0011
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0013	0.0005	0.0024
Plasmodium vivax	calcium-dependent protein kinase 1, putative	0.0067	0.0597	0.0597
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0013	0.0005	0.0011
Brugia malayi	ORL1-like opioid receptor	0.0013	0.0005	0.0024
Echinococcus granulosus	7TM GPCR rhodopsin	0.0013	0.0005	0.0011
Trichomonas vaginalis	conserved hypothetical protein	0.0031	0.0201	0.0894
Schistosoma mansoni	glucose transport protein	0.0217	0.2253	1
Trypanosoma brucei	glucose transporter, putative	0.0067	0.0606	0.8651
Wolbachia endosymbiont of Brugia malayi	major facilitator superfamily permease	0.0031	0.0201	1
Echinococcus granulosus	tm gpcr rhodopsin	0.0013	0.0005	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Mycobacterium tuberculosis	Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase)	0.0041	0.0318	0.1374
Echinococcus multilocularis	allatostatin A receptor	0.0013	0.0005	0.0011
Onchocerca volvulus	Putative transporter	0.0031	0.0201	0.1335
Brugia malayi	bifunctional aminoacyl-tRNA synthetase	0.0065	0.0582	0.2583
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0013	0.0005	0.0011
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Trichomonas vaginalis	penicillin-binding protein, putative	0.0035	0.0249	0.1106
Schistosoma mansoni	growth hormone secretagogue receptor	0.0013	0.0005	0.0024
Trypanosoma cruzi	hexose transporter, putative	0.0031	0.0201	0.2874
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Loa Loa (eye worm)	CAMK/CAMK2 protein kinase	0.0066	0.0597	0.2648
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Toxoplasma gondii	facilitative glucose transporter GT1	0.0217	0.2253	0.3408
Trypanosoma cruzi	glucose transporter, putative	0.0031	0.0201	0.2874
Schistosoma mansoni	hypothetical protein	0.0217	0.2253	1
Echinococcus multilocularis	calcium dependent protein kinase	0.0062	0.0552	0.1124
Loa Loa (eye worm)	TYRA-2 protein	0.0013	0.0005	0.0024
Entamoeba histolytica	prolyl-tRNA synthetase, putative	0.0065	0.0582	0.9752
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0013	0.0005	0.0011
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0013	0.0005	0.0011
Treponema pallidum	prolyl-tRNA synthetase	0.0023	0.0119	1
Schistosoma mansoni	sugar transporter	0.0031	0.0201	0.0894
Trichomonas vaginalis	ap endonuclease, putative	0.0018	0.0066	0.0292
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Mycobacterium ulcerans	fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE	0.0035	0.0249	0.6253
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Echinococcus granulosus	sex peptide receptor	0.0013	0.0005	0.0011
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0013	0.0005	0.0011
Echinococcus multilocularis	calcium:calmodulin dependent protein kinase type	0.0066	0.0597	0.1216
Brugia malayi	G-protein coupled receptor	0.0013	0.0005	0.0024
Brugia malayi	G protein-coupled receptor	0.0013	0.0005	0.0024
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0013	0.0005	0.0011
Echinococcus granulosus	g protein coupled receptor	0.0013	0.0005	0.0011
Brugia malayi	Cam kinase protein 1	0.0066	0.0597	0.2648
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0013	0.0005	0.0011
Trypanosoma cruzi	hexose transporter	0.0067	0.0606	0.8651
Loa Loa (eye worm)	hypothetical protein	0.0066	0.0597	0.2648
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0013	0.0005	0.0024
Schistosoma mansoni	glucose transporter	0.0031	0.0201	0.0894
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Echinococcus granulosus	rhodopsin orphan GPCR	0.0013	0.0005	0.0011
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0013	0.0005	0.0024
Brugia malayi	Sugar transporter family protein	0.0031	0.0201	0.0894
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Echinococcus multilocularis	glutamyl tRNA synthetase cytoplasmic	0.0065	0.0582	0.1186
Mycobacterium leprae	Probable lipase LipE	0.0035	0.0249	0.4283
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Echinococcus granulosus	tm gpcr rhodopsin	0.0013	0.0005	0.0011
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0013	0.0005	0.0024
Schistosoma mansoni	amine GPCR	0.0013	0.0005	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Echinococcus multilocularis	solute carrier family 22	0.0031	0.0201	0.041
Leishmania major	hypothetical protein, conserved	0.0035	0.0249	0.3558
Plasmodium vivax	calcium-dependent protein kinase 3, putative	0.0067	0.0597	0.0597
Trichomonas vaginalis	conserved hypothetical protein	0.0031	0.0201	0.0894
Brugia malayi	lysyl-tRNA synthetase	0.0048	0.0399	0.1769
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0046	0.0372	0.0758
Schistosoma mansoni	myosin xvIII	0.0013	0.0005	0.0024
Brugia malayi	hypothetical protein	0.0013	0.0005	0.0024
Plasmodium falciparum	proline--tRNA ligase	0.0076	0.0701	0.0701
Echinococcus multilocularis	solute carrier family 22	0.0031	0.0201	0.041
Echinococcus granulosus	glutamyl tRNA synthetase cytoplasmic	0.0065	0.0582	0.1186
Trichomonas vaginalis	conserved hypothetical protein	0.0067	0.0606	0.269
Echinococcus multilocularis	beta LACTamase domain containing family member	0.0035	0.0249	0.0508
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Brugia malayi	Dopamine receptor	0.0013	0.0005	0.0024
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Onchocerca volvulus		0.0031	0.0201	0.1335
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0201	0.0894
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0013	0.0005	0.0011
Echinococcus multilocularis	fmrfamide receptor	0.0013	0.0005	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Trichomonas vaginalis	sugar transporter, putative	0.0031	0.0201	0.0894
Schistosoma mansoni	lysyl-tRNA synthetase	0.0048	0.0399	0.1769
Giardia lamblia	Sugar-proton symporter	0.0031	0.0201	0.346
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Brugia malayi	major facilitator superfamily protein	0.0031	0.0201	0.0894
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0013	0.0005	0.0024
Echinococcus granulosus	rhodopsin orphan GPCR	0.0013	0.0005	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0448	0.1987
Echinococcus multilocularis	lysyl tRNA synthetase	0.0048	0.0399	0.0812
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0013	0.0005	0.0024
Trypanosoma cruzi	lysyl-tRNA synthetase, putative	0.0048	0.0399	0.5689
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0066	0.0597	0.1216
Mycobacterium leprae	Possible lysyl-tRNA synthetase 2 LysX	0.0048	0.0399	0.6849
Schistosoma mansoni	glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs)	0.0065	0.0582	0.2583
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0013	0.0005	0.0011
Echinococcus granulosus	calcium:calmodulin dependent protein kinase type	0.0066	0.0597	0.1216
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0013	0.0005	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Schistosoma mansoni	protein kinase	0.0066	0.0597	0.2648
Onchocerca volvulus		0.0031	0.0201	0.1335
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0046	0.0372	0.0758
Loa Loa (eye worm)	major facilitator superfamily transporter	0.0031	0.0201	0.0894
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0046	0.0372	0.1651
Schistosoma mansoni	neuropeptide receptor	0.0013	0.0005	0.0024
Mycobacterium tuberculosis	Probable lipase LipE	0.0035	0.0249	0.1076
Echinococcus multilocularis	neuropeptides capa receptor	0.0013	0.0005	0.0011
Leishmania major	glucose transporter/membrane transporter D2, putative	0.0067	0.0606	0.8651
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0201	0.0894
Brugia malayi	hypothetical protein	0.0013	0.0005	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0013	0.0005	0.0024
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Brugia malayi	hypothetical protein	0.0031	0.0201	0.0894
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0013	0.0005	0.0011
Leishmania major	prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative	0.0076	0.0701	1
Loa Loa (eye worm)	hypothetical protein	0.0013	0.0005	0.0024
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0013	0.0005	0.0024
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0013	0.0005	0.0024
Brugia malayi	sulfakinin receptor protein	0.0013	0.0005	0.0024
Brugia malayi	neuropeptide F receptor	0.0013	0.0005	0.0024
Schistosoma mansoni	biogenic amine receptor	0.0013	0.0005	0.0024
Echinococcus granulosus	g protein coupled receptor	0.0013	0.0005	0.0011
Brugia malayi	follicle stimulating hormone receptor	0.0013	0.0005	0.0024

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Search by Saint Jude

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 763743