Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | carboxylesterase | 0.0068 | 0.0475 | 0.0682 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0205 | 0.2227 | 0.32 |
Schistosoma mansoni | nuclear receptor | 0.0097 | 0.0837 | 0.1606 |
Schistosoma mansoni | single-minded | 0.0047 | 0.0199 | 0.0354 |
Echinococcus granulosus | jun protein | 0.0246 | 0.2749 | 0.7944 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0205 | 0.2227 | 0.8071 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0135 | 0.023 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0205 | 0.2227 | 0.8071 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0108 | 0.0986 | 0.1898 |
Brugia malayi | hypothetical protein | 0.0097 | 0.0837 | 0.1203 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0205 | 0.2227 | 0.4333 |
Brugia malayi | Carboxylesterase family protein | 0.0068 | 0.0475 | 0.0682 |
Schistosoma mansoni | hypothetical protein | 0.02 | 0.2158 | 0.4198 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0387 | 1 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0042 | 0.0135 | 0.0195 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0387 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0249 | 0.2796 | 0.4018 |
Loa Loa (eye worm) | hypothetical protein | 0.0574 | 0.6958 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.03 | 0.3449 | 0.6731 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.03 | 0.3449 | 1 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0387 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0097 | 0.0837 | 0.3637 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0068 | 0.0475 | 0.1599 |
Onchocerca volvulus | 0.0097 | 0.0837 | 0.3637 | |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0215 | 0.2361 | 0.6805 |
Brugia malayi | nuclear receptor RXR | 0.0108 | 0.0986 | 0.1417 |
Brugia malayi | hypothetical protein | 0.0108 | 0.0986 | 0.1417 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0205 | 0.2227 | 0.32 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0135 | 0.0195 |
Brugia malayi | hypothetical protein | 0.0193 | 0.2072 | 0.2978 |
Brugia malayi | hypothetical protein | 0.0097 | 0.0837 | 0.1203 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0194 | 0.0344 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0108 | 0.0986 | 0.2769 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0205 | 0.2227 | 0.8071 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.0214 | 0.0307 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0387 | 1 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0097 | 0.0837 | 0.2936 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0214 | 0.0307 |
Brugia malayi | nuclear receptor NHR-67 | 0.0097 | 0.0837 | 0.1203 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.2227 | 0.32 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.0163 | 0.0234 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0205 | 0.2227 | 0.4333 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0205 | 0.2227 | 0.32 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0056 | 0.0318 | 0.8225 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0163 | 0.0354 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0097 | 0.0837 | 0.2332 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0387 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0837 | 0.1203 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0215 | 0.2361 | 0.8566 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0837 | 0.1203 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.2227 | 0.32 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0205 | 0.2227 | 0.32 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0108 | 0.0986 | 0.1417 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0097 | 0.0837 | 0.1203 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0097 | 0.0837 | 0.1203 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0205 | 0.2227 | 0.4333 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0042 | 0.0135 | 0.0195 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0205 | 0.2227 | 0.32 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0205 | 0.2227 | 0.32 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0205 | 0.2227 | 1 |
Echinococcus granulosus | Ankyrin | 0.0042 | 0.014 | 0.0287 |
Schistosoma mansoni | nuclear hormone receptor | 0.0097 | 0.0837 | 0.1606 |
Brugia malayi | small heat shock protein | 0.0574 | 0.6958 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0205 | 0.2227 | 0.32 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0205 | 0.2227 | 1 |
Echinococcus multilocularis | jun protein | 0.0246 | 0.2749 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0246 | 0.2749 | 0.7944 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0097 | 0.0837 | 0.2332 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0097 | 0.0837 | 0.3637 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0246 | 0.2749 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0097 | 0.0837 | 0.1203 |
Brugia malayi | hypothetical protein | 0.0228 | 0.2528 | 0.3634 |
Mycobacterium ulcerans | putative regulatory protein | 0.0035 | 0.0042 | 0.0042 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0205 | 0.2227 | 0.32 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0837 | 0.1203 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0042 | 0.0135 | 0.0274 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0205 | 0.2227 | 0.32 |
Brugia malayi | ecdysone receptor | 0.0097 | 0.0837 | 0.1203 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0042 | 0.0135 | 0.0274 |
Schistosoma mansoni | thyroid hormone receptor | 0.0205 | 0.2227 | 0.4333 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0205 | 0.2227 | 0.4333 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0205 | 0.2227 | 0.6412 |
Onchocerca volvulus | 0.0097 | 0.0837 | 0.3637 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0205 | 0.2227 | 0.32 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.043 | 0.5116 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.2227 | 0.32 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0387 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0097 | 0.0837 | 0.2332 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0047 | 0.0199 | 0.0354 |
Brugia malayi | Death domain containing protein | 0.0042 | 0.0135 | 0.0195 |
Onchocerca volvulus | Netrin receptor homolog | 0.0042 | 0.0135 | 0.0427 |
Brugia malayi | bZIP transcription factor family protein | 0.0246 | 0.2749 | 0.3951 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0018 | 0.0026 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0194 | 0.0278 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0097 | 0.0837 | 0.1203 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0163 | 0.0354 |
Schistosoma mansoni | nuclear receptor | 0.0097 | 0.0837 | 0.1606 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.2227 | 0.32 |
Brugia malayi | conserved hypotetical protein | 0.0097 | 0.0837 | 0.1203 |
Schistosoma mansoni | zinc finger protein | 0.0097 | 0.0837 | 0.1606 |
Schistosoma mansoni | jun-related protein | 0.02 | 0.2158 | 0.4198 |
Brugia malayi | nuclear receptor NHR-88 | 0.0205 | 0.2227 | 0.32 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0837 | 0.1203 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0205 | 0.2227 | 0.4333 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0205 | 0.2227 | 0.6412 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.014 | 0.0201 |
Echinococcus granulosus | carboxylesterase 5A | 0.0068 | 0.0475 | 0.127 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0387 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0042 | 0.0135 | 0.0195 |
Brugia malayi | ecdysteroid receptor | 0.0205 | 0.2227 | 0.32 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0097 | 0.0837 | 0.1203 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.2227 | 0.32 |
Echinococcus granulosus | acetylcholinesterase | 0.0068 | 0.0475 | 0.127 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0205 | 0.2227 | 0.32 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0205 | 0.2227 | 0.8071 |
Echinococcus multilocularis | Ankyrin | 0.0042 | 0.014 | 0.0362 |
Echinococcus granulosus | FTZ F1 alpha | 0.0205 | 0.2227 | 0.6412 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0205 | 0.2227 | 0.8071 |
Schistosoma mansoni | coup transcription factor | 0.0205 | 0.2227 | 0.4333 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0475 | 0.0682 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0228 | 0.2528 | 0.7297 |
Brugia malayi | Cytochrome P450 family protein | 0.01 | 0.0879 | 0.1264 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.2227 | 0.32 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0205 | 0.2227 | 0.4333 |
Brugia malayi | bHLH-PAS transcription factor | 0.0035 | 0.0042 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0837 | 0.1203 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0205 | 0.2227 | 0.6412 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0163 | 0.0284 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0205 | 0.2227 | 0.8071 |
Brugia malayi | hypoxia-induced factor 1 | 0.0145 | 0.1463 | 0.2102 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0387 | 1 |
Brugia malayi | PAS domain containing protein | 0.0047 | 0.0199 | 0.0286 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0018 | 0.0026 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0205 | 0.2227 | 0.32 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0986 | 0.1417 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0097 | 0.0837 | 0.1203 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.2227 | 0.32 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0837 | 0.1203 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0986 | 0.1417 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0097 | 0.0837 | 0.2332 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0205 | 0.2227 | 0.4333 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0097 | 0.0837 | 0.2332 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0163 | 0.0446 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0097 | 0.0837 | 0.1203 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.01 | 0.0879 | 0.1264 |
Brugia malayi | follicle stimulating hormone receptor | 0.0249 | 0.2796 | 0.4018 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0837 | 0.1203 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0475 | 0.0682 |
Schistosoma mansoni | nuclear hormone receptor | 0.0097 | 0.0837 | 0.1606 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0387 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0387 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0205 | 0.2227 | 0.32 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.0214 | 0.0307 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0387 | 1 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0194 | 0.0344 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0192 | 0.2059 | 0.7453 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0163 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0986 | 0.1417 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0205 | 0.2227 | 0.8071 |
Onchocerca volvulus | 0.0193 | 0.2072 | 0.929 | |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0042 | 0.0135 | 0.0345 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0108 | 0.0986 | 0.1417 |
Brugia malayi | hypothetical protein | 0.0108 | 0.0986 | 0.1417 |
Brugia malayi | Carboxylesterase family protein | 0.0068 | 0.0475 | 0.0682 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0145 | 0.1463 | 0.2102 |
Brugia malayi | nuclear receptor NHR-88 | 0.0097 | 0.0837 | 0.1203 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0108 | 0.0986 | 0.3486 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0163 | 0.0284 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0097 | 0.0837 | 0.1203 |
Schistosoma mansoni | nuclear hormone receptor | 0.0205 | 0.2227 | 0.4333 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0097 | 0.0837 | 0.1606 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0837 | 0.1203 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0205 | 0.2227 | 0.32 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0042 | 0.0135 | 0.0345 |
Mycobacterium ulcerans | proteasome PrcA | 0.081 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0205 | 0.2227 | 0.32 |
Loa Loa (eye worm) | DR-78 | 0.0097 | 0.0837 | 0.1203 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0205 | 0.2227 | 0.32 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0387 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0228 | 0.2528 | 0.3634 |
Echinococcus granulosus | acetylcholinesterase | 0.0068 | 0.0475 | 0.127 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0205 | 0.2227 | 0.32 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0097 | 0.0837 | 0.1606 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0228 | 0.2528 | 0.9185 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0205 | 0.2227 | 0.8071 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0986 | 0.1417 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0205 | 0.2227 | 0.6412 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0205 | 0.2227 | 0.32 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0108 | 0.0986 | 0.1417 |
Brugia malayi | steroid hormone receptor | 0.0205 | 0.2227 | 0.32 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0837 | 0.1203 |
Brugia malayi | nuclear hormone receptor | 0.0205 | 0.2227 | 0.32 |
Onchocerca volvulus | 0.0205 | 0.2227 | 1 | |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0068 | 0.0475 | 0.0682 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0163 | 0.0446 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.2227 | 0.32 |
Onchocerca volvulus | 0.0047 | 0.0194 | 0.0694 | |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0205 | 0.2227 | 0.32 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0108 | 0.0986 | 0.1898 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0097 | 0.0837 | 0.2936 |
Brugia malayi | hypothetical protein | 0.0158 | 0.162 | 0.2328 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0387 | 1 |
Mycobacterium tuberculosis | Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. | 0.081 | 1 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0068 | 0.0475 | 0.0896 |
Echinococcus granulosus | death domain containing protein | 0.0042 | 0.0135 | 0.0274 |
Echinococcus multilocularis | acetylcholinesterase | 0.0068 | 0.0475 | 0.1599 |
Echinococcus multilocularis | acetylcholinesterase | 0.0068 | 0.0475 | 0.1599 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0048 | 0.0217 | 0.5622 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0986 | 0.1417 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0205 | 0.2227 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0205 | 0.2227 | 0.32 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0387 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0205 | 0.2227 | 0.4333 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0097 | 0.0837 | 0.1203 |
Brugia malayi | tailless protein | 0.0097 | 0.0837 | 0.1203 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0837 | 0.1203 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 0.0163 | 0.0234 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0205 | 0.2227 | 0.32 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0062 | 0.0387 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0097 | 0.0837 | 0.1203 |
Schistosoma mansoni | netrin receptor unc5 | 0.0042 | 0.0135 | 0.023 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0042 | 0.0135 | 0.023 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0205 | 0.2227 | 0.32 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0837 | 0.1203 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0205 | 0.2227 | 0.6412 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0097 | 0.0837 | 0.2332 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0837 | 0.1203 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0205 | 0.2227 | 0.6412 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0097 | 0.0837 | 0.2936 |
Brugia malayi | nuclear hormone receptor | 0.0097 | 0.0837 | 0.1203 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0097 | 0.0837 | 0.2936 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0205 | 0.2227 | 0.8071 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0387 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0097 | 0.0837 | 0.2936 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.0214 | 0.0307 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0042 | 0.014 | 0.0239 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0387 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0239 | 0.2662 | 0.3827 |
Schistosoma mansoni | thyroid hormone receptor | 0.0205 | 0.2227 | 0.4333 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.162 | 0.2328 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.0837 | 0.1203 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0387 | 1 |
Brugia malayi | Uncoordinated protein 44 | 0.0042 | 0.0135 | 0.0195 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0205 | 0.2227 | 0.32 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0205 | 0.2227 | 0.32 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0205 | 0.2227 | 0.6412 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 20 % | Inhibition of Protein phosphatase 2B (PP2B) at 0.1 mM | ChEMBL. | No reference |
Inhibition (binding) | = 40 % | Inhibition of Protein phosphatase 2A1 (PP2A1) at 0.1 mM | ChEMBL. | No reference |
Inhibition (binding) | = 50 % | Inhibition of Protein phosphatase 1 at 0.1 mM | ChEMBL. | No reference |
Inhibition (binding) | = 80 % | Inhibition of Protein phosphatase 1 at 1 mM | ChEMBL. | No reference |
Inhibition (binding) | = 89 % | Inhibition of Protein phosphatase 2B (PP2B) at 1 mM | ChEMBL. | No reference |
Inhibition (binding) | = 90 % | Inhibition of Protein phosphatase 2A1 (PP2A1) at 1 mM | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.