Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | alpha glucosidase II subunit, putative | 0.0036 | 0 | 0.5 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0 | 0.5 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0075 | 0.318 | 0.318 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0073 | 0.2998 | 0.2998 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0 | 0.5 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0075 | 0.318 | 0.318 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0075 | 0.318 | 0.318 |
Trypanosoma brucei | glucosidase, putative | 0.0036 | 0 | 0.5 |
Loa Loa (eye worm) | calcium channel | 0.0075 | 0.318 | 0.318 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0161 | 1 | 1 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0046 | 0.0819 | 0.0819 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.3395 | 0.3395 |
Schistosoma mansoni | alpha-glucosidase | 0.0138 | 0.821 | 1 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0075 | 0.318 | 0.318 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0508 | 0.0618 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0153 | 0.9359 | 0.9359 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0036 | 0 | 0.5 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0042 | 0.0508 | 0.0508 |
Schistosoma mansoni | high voltage-activated calcium channel Cav1 | 0.0075 | 0.318 | 0.3874 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0161 | 1 | 1 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0075 | 0.318 | 0.318 |
Schistosoma mansoni | voltage-gated cation channel | 0.0075 | 0.318 | 0.3874 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0075 | 0.318 | 0.318 |
Brugia malayi | Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog | 0.0075 | 0.318 | 0.318 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0121 | 0.6868 | 0.6868 |
Onchocerca volvulus | 0.0093 | 0.4581 | 0.5 | |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0161 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0 | 0.5 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0036 | 0 | 0.5 |
Brugia malayi | PHD-finger family protein | 0.0051 | 0.1204 | 0.1204 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0078 | 0.3384 | 0.3384 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0 | 0.5 |
Schistosoma mansoni | zinc finger protein | 0.004 | 0.0335 | 0.0409 |
Schistosoma mansoni | bromodomain containing protein | 0.0129 | 0.7451 | 0.9075 |
Schistosoma mansoni | alpha-glucosidase | 0.0138 | 0.821 | 1 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 | 0.0075 | 0.318 | 0.318 |
Echinococcus multilocularis | zinc finger protein | 0.004 | 0.0335 | 0.0335 |
Schistosoma mansoni | high voltage-activated calcium channel Cav2A | 0.0075 | 0.318 | 0.3874 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.4092 | 0.4092 |
Echinococcus granulosus | zinc finger protein | 0.004 | 0.0335 | 0.0335 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0073 | 0.2998 | 0.2998 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0046 | 0.0819 | 0.0997 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0036 | 0 | 0.5 |
Echinococcus granulosus | voltage dependent L type calcium channel subunit|voltage dependent calcium channel | 0.0075 | 0.318 | 0.318 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0 | 0.5 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0046 | 0.0819 | 0.0819 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.318 | 0.318 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0161 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.8663 | 0.8663 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0 | 0.5 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0075 | 0.318 | 0.318 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0 | 0.5 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0121 | 0.6868 | 0.6868 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0036 | 0.0024 | 0.0024 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.3781 | 0.3781 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu | 0.0075 | 0.318 | 0.318 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.