Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.3556 | 0.5 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.2068 | 0.2325 |
Echinococcus multilocularis | zinc finger protein | 0.0019 | 0.0847 | 0.0592 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.1022 | 0.1112 |
Echinococcus multilocularis | musashi | 0.0026 | 0.2068 | 0.2325 |
Brugia malayi | Bromodomain containing protein | 0.0037 | 0.3939 | 0.3939 |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.0141 | 0.5 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.2068 | 0.2068 |
Echinococcus granulosus | lamin | 0.0026 | 0.2068 | 0.2325 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.9294 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.4342 | 0.4672 |
Trypanosoma brucei | ISWI complex protein | 0.0015 | 0.0141 | 0.5 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.1337 | 0.1287 |
Leishmania major | hypothetical protein, conserved | 0.0015 | 0.0141 | 0.5 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.2068 | 0.2325 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.2068 | 0.2225 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0016 | 0.043 | 0.0366 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.3556 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.3556 | 0.5 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.2068 | 0.2432 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.3556 | 0.431 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.2068 | 0.2225 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.3548 | 0.4427 |
Echinococcus granulosus | zinc finger protein | 0.0019 | 0.0847 | 0.0592 |
Onchocerca volvulus | 0.0026 | 0.2068 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.1986 | 0.2137 |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.0141 | 0.5 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0016 | 0.043 | 0.0366 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.2068 | 0.2068 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.1337 | 0.1287 |
Echinococcus multilocularis | lamin | 0.0026 | 0.2068 | 0.2325 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.3951 | 0.4251 |
Brugia malayi | PHD-finger family protein | 0.0024 | 0.1728 | 0.1728 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.3548 | 0.4427 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0058 | 0.7474 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.2068 | 0.2225 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.2068 | 0.2325 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0058 | 0.7474 | 1 |
Onchocerca volvulus | 0.0026 | 0.2068 | 0.5 | |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.3556 | 0.4437 |
Schistosoma mansoni | bromodomain containing protein | 0.0061 | 0.8065 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.3556 | 0.431 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.3556 | 0.4437 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.1337 | 0.151 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0016 | 0.043 | 0.0366 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.4657 | 0.5011 |
Schistosoma mansoni | lamin | 0.0026 | 0.2068 | 0.2432 |
Brugia malayi | hypothetical protein | 0.0035 | 0.3556 | 0.3556 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0016 | 0.043 | 0.0366 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.3556 | 0.5 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.1022 | 0.1099 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.043 | 0.0463 |
Schistosoma mansoni | zinc finger protein | 0.0019 | 0.0847 | 0.0891 |
Schistosoma mansoni | lamin | 0.0026 | 0.2068 | 0.2432 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0017 | 0.0532 | 0.0572 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.