Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0021 | 0.0307 | 0.5 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0021 | 0.0307 | 0.5 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0535 | 0.0679 |
Toxoplasma gondii | propionate-CoA ligase | 0.0021 | 0.0307 | 0.5 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.007 | 0.9544 | 1 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0021 | 0.0307 | 0.5 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0053 | 0.6238 | 0.6421 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.007 | 0.9544 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.007 | 0.9544 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0021 | 0.0307 | 0.0124 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0021 | 0.0307 | 0.5 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.007 | 0.9544 | 1 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0053 | 0.6238 | 1 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0053 | 0.6238 | 0.5 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0021 | 0.0307 | 0.0389 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0535 | 0.0739 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0021 | 0.0307 | 0.5 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.005 | 0.5705 | 0.5844 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0058 | 0.724 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.007 | 0.9544 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.3818 | 0.3878 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0191 | 0.0242 |
Brugia malayi | Bromodomain containing protein | 0.0037 | 0.3378 | 0.3168 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.007 | 0.9544 | 1 |
Brugia malayi | PHD-finger family protein | 0.0024 | 0.0963 | 0.0676 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.005 | 0.5705 | 0.5844 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.9544 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.2951 | 0.4076 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0021 | 0.0307 | 0.0424 |
Brugia malayi | AMP-binding enzyme family protein | 0.007 | 0.9544 | 0.9529 |
Mycobacterium ulcerans | hypothetical protein | 0.007 | 0.9544 | 1 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.007 | 0.9544 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.007 | 0.9544 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.9544 | 1 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0021 | 0.0307 | 0.5 |
Brugia malayi | AMP-binding enzyme family protein | 0.007 | 0.9544 | 0.9529 |
Onchocerca volvulus | 0.007 | 0.9544 | 1 | |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.005 | 0.5705 | 0.5844 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0021 | 0.0307 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0307 | 0.0124 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.007 | 0.9544 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.6238 | 0.6466 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.007 | 0.9544 | 1 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0021 | 0.0307 | 0.5 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.007 | 0.9544 | 1 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0021 | 0.0307 | 0.0424 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.6238 | 0.6466 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.9544 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.007 | 0.9544 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.6238 | 0.6466 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0021 | 0.0307 | 0.0124 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0021 | 0.0307 | 0.5 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.007 | 0.9544 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0062 | 0.7886 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.005 | 0.5705 | 0.5844 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0307 | 0.0124 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.3391 | 0.3422 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0053 | 0.6238 | 0.6421 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.007 | 0.9544 | 1 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0053 | 0.6238 | 1 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0021 | 0.0307 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.6238 | 0.6466 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0058 | 0.724 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.007 | 0.9544 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.007 | 0.9544 | 0.9529 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.6238 | 0.6466 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.007 | 0.9544 | 1 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0021 | 0.0307 | 0.0124 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.9228 | 0.9662 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.2951 | 0.4076 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0535 | 0.0739 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.007 | 0.9544 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.4163 | 0.4247 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.