Detailed information for compound 803868

Basic information

Technical information
  • TDR Targets ID: 803868
  • Name: 2-[[2-(4-chlorophenyl)-5-phenyl-1H-imidazol-4 -yl]sulfanyl]-N-(1,3-thiazol-2-yl)acetamide
  • MW: 426.942 | Formula: C20H15ClN4OS2
  • H donors: 2 H acceptors: 3 LogP: 4.95 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1nccs1)CSc1nc([nH]c1c1ccccc1)c1ccc(cc1)Cl
  • InChi: 1S/C20H15ClN4OS2/c21-15-8-6-14(7-9-15)18-24-17(13-4-2-1-3-5-13)19(25-18)28-12-16(26)23-20-22-10-11-27-20/h1-11H,12H2,(H,24,25)(H,22,23,26)
  • InChiKey: CLDVNFSEXRJDID-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-[[2-(4-chlorophenyl)-5-phenyl-1H-imidazol-4-yl]sulfanyl]-N-thiazol-2-yl-acetamide
  • 2-[[2-(4-chlorophenyl)-5-phenyl-1H-imidazol-4-yl]thio]-N-(2-thiazolyl)acetamide
  • 2-[[2-(4-chlorophenyl)-5-phenyl-1H-imidazol-4-yl]thio]-N-thiazol-2-yl-acetamide
  • 2-[[2-(4-chlorophenyl)-5-phenyl-1H-imidazol-4-yl]sulfanyl]-N-(1,3-thiazol-2-yl)ethanamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum tyrosine kinase-like protein 0.0077 0.0744 0.8519
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0429 0.0365
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0015 0.0018 0.0022
Toxoplasma gondii Tyrosine kinase-like (TKL) protein 0.0077 0.0744 0.5513
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0674 0.0611
Echinococcus granulosus tumor protein p63 0.034 0.3829 0.3833
Echinococcus granulosus intermediate filament protein 0.0028 0.0171 0.0168
Plasmodium falciparum thioredoxin reductase 0.003 0.0198 0.1651
Brugia malayi coiled-coil like protein 1 0.0077 0.0744 0.0734
Echinococcus multilocularis thioredoxin glutathione reductase 0.0087 0.0867 0.0869
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0124 0.1295 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0198 0.1068
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0058 0.053 0.0466
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.007 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.1295 0.1558
Toxoplasma gondii thioredoxin reductase 0.0087 0.0861 0.6471
Brugia malayi Neurabin protein 1 0.0077 0.0744 0.0734
Giardia lamblia PHD finger protein 15 0.0058 0.053 1
Brugia malayi WGR domain containing protein 0.0124 0.1295 0.1292
Echinococcus granulosus liprin beta 1 0.0077 0.0744 0.0742
Echinococcus granulosus PHD finger protein rhinoceros 0.0058 0.053 0.0528
Echinococcus granulosus thioredoxin glutathione reductase 0.0087 0.0867 0.0866
Brugia malayi hypothetical protein 0.0077 0.0744 0.0734
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0124 0.1295 0.1236
Loa Loa (eye worm) hypothetical protein 0.0077 0.0744 0.0817
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.003 0.0198 0.155
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0198 0.1068
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.022 0.242 1
Plasmodium vivax tyrosine kinase-like protein, putative 0.0077 0.0744 0.7998
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.003 0.0198 0.1068
Plasmodium vivax hypothetical protein, conserved 0.0019 0.007 0.0033
Onchocerca volvulus 0.0077 0.0744 0.0652
Echinococcus granulosus Sterile alpha motif SAM 0.0077 0.0744 0.0742
Schistosoma mansoni jumonji domain containing protein 0.0152 0.1625 0.1568
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.022 0.242 1
Echinococcus granulosus sterile alpha and tir motif containing protein 0.0077 0.0744 0.0742
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0022 0.0105 0.0086
Schistosoma mansoni poly [ADP-ribose] polymerase 0.0124 0.1295 0.1236
Brugia malayi hypothetical protein 0.0077 0.0744 0.0734
Onchocerca volvulus 0.0091 0.0913 0.0845
Schistosoma mansoni hypothetical protein 0.0077 0.0744 0.0681
Echinococcus multilocularis tumor protein p63 0.034 0.3829 0.3835
Echinococcus granulosus jumonji domain containing protein 0.0081 0.0798 0.0796
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0013 0.0004 0.0005
Brugia malayi glutathione reductase 0.0087 0.0861 0.0853
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0171 0.0188
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.003 0.0198 0.018
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.003 0.0198 0.0195
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0019 0.007 0.0023
Echinococcus granulosus lamin 0.0028 0.0171 0.0168
Trichomonas vaginalis mercuric reductase, putative 0.003 0.0198 0.0238
Plasmodium vivax hypothetical protein, conserved 0.0058 0.053 0.547
Brugia malayi Liprin-alpha 2 0.0077 0.0744 0.0734
Echinococcus multilocularis poly (adp ribose) polymerase 2 0.0124 0.1295 0.1297
Echinococcus multilocularis PHD finger protein rhinoceros 0.0058 0.053 0.0531
Treponema pallidum NADH oxidase 0.003 0.0198 0.5
Echinococcus granulosus lamin dm0 0.0028 0.0171 0.0168
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0198 0.1068
Plasmodium vivax thioredoxin reductase, putative 0.0087 0.0861 0.9389
Brugia malayi WGR domain containing protein 0.0124 0.1295 0.1292
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.003 0.0198 0.1651
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0198 0.1068
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0744 0.0895
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0198 0.1068
Loa Loa (eye worm) hypothetical protein 0.0077 0.0744 0.0817
Loa Loa (eye worm) hypothetical protein 0.0058 0.053 0.0582
Leishmania major trypanothione reductase 0.0087 0.0861 1
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0067 0.0067
Loa Loa (eye worm) toll and interleukin 1 receptor domain-containing protein isoform f 0.0077 0.0744 0.0817
Onchocerca volvulus Alhambra homolog 0.0058 0.053 0.0409
Brugia malayi Pre-SET motif family protein 0.0091 0.0913 0.0905
Loa Loa (eye worm) thioredoxin reductase 0.0087 0.0861 0.0946
Trypanosoma cruzi trypanothione reductase, putative 0.003 0.0198 0.1068
Echinococcus multilocularis peregrin 0.0058 0.053 0.0531
Entamoeba histolytica hypothetical protein 0.0124 0.1295 0.5
Loa Loa (eye worm) hypothetical protein 0.0028 0.0171 0.0188
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.003 0.0198 0.1068
Entamoeba histolytica hypothetical protein 0.0124 0.1295 0.5
Onchocerca volvulus 0.0077 0.0744 0.0652
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.003 0.0198 0.1651
Loa Loa (eye worm) jmjC domain-containing protein 0.0071 0.0674 0.074
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.022 0.242 1
Echinococcus multilocularis poly (ADP ribose) polymerase 0.0124 0.1295 0.1297
Echinococcus multilocularis stromal interaction molecule 1 0.0077 0.0744 0.0745
Echinococcus granulosus peregrin 0.0058 0.053 0.0528
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0067 0.0064
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0124 0.1295 1
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0198 0.1651
Loa Loa (eye worm) hypothetical protein 0.0019 0.0067 0.0074
Trichomonas vaginalis set domain proteins, putative 0.0723 0.831 1
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0022 0.0105 0.0086
Loa Loa (eye worm) hypothetical protein 0.0077 0.0744 0.0817
Echinococcus granulosus liprin alpha 2 0.0077 0.0744 0.0742
Echinococcus multilocularis musashi 0.0028 0.0171 0.0171
Toxoplasma gondii PHD-finger domain-containing protein 0.0019 0.007 0.0023
Mycobacterium tuberculosis Probable dehydrogenase 0.0198 0.2162 0.8837
Schistosoma mansoni lamin 0.0028 0.0171 0.0105
Brugia malayi jmjC domain containing protein 0.0019 0.0067 0.0047
Echinococcus multilocularis lamin 0.0028 0.0171 0.0171
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.1295 0.1558
Echinococcus multilocularis poly (ADP ribose) polymerase 1 0.0124 0.1295 0.1297
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0088 0.0874 0.0872
Loa Loa (eye worm) hypothetical protein 0.0077 0.0744 0.0817
Loa Loa (eye worm) PHD-finger family protein 0.0058 0.053 0.0582
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0067 0.0064
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0067 0.0067
Plasmodium falciparum thioredoxin reductase 0.0087 0.0861 1
Brugia malayi Bromodomain containing protein 0.0058 0.053 0.0517
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.1295 0.1558
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.002 0.0022
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.053 0.377
Echinococcus granulosus poly ADP ribose polymerase 1 0.0124 0.1295 0.1294
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.003 0.0198 0.1651
Plasmodium vivax glutathione reductase, putative 0.0087 0.0861 0.9389
Brugia malayi PHD-finger family protein 0.0058 0.053 0.0517
Trichomonas vaginalis c2h2 zinc finger protein, putative 0.0077 0.0744 0.0895
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0198 0.1068
Plasmodium falciparum protein kinase, putative 0.0077 0.0744 0.8519
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0087 0.0861 0.2985
Onchocerca volvulus 0.005 0.0429 0.0294
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0067 0.0074
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0198 0.2162 0.8837
Toxoplasma gondii NADPH-glutathione reductase 0.003 0.0198 0.1068
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.1295 0.1558
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0091 0.0913 0.6892
Loa Loa (eye worm) poly(ADP-ribose) polymerase 0.0124 0.1295 0.1423
Brugia malayi jmjC domain containing protein 0.0191 0.2085 0.2094
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0913 0.0852
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0067 0.0074
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.053 0.377
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0067 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.1295 0.1558
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0198 0.2162 0.8837
Mycobacterium tuberculosis Probable reductase 0.0198 0.2162 0.8837
Loa Loa (eye worm) hypothetical protein 0.0091 0.0913 0.1003
Schistosoma mansoni hypothetical protein 0.0019 0.007 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.1295 0.1558
Echinococcus granulosus tankyrase 0.0866 0.9986 1
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.003 0.0198 0.5
Loa Loa (eye worm) hypothetical protein 0.01 0.1018 0.1119
Trichomonas vaginalis glutathione reductase, putative 0.003 0.0198 0.0238
Schistosoma mansoni hypothetical protein 0.0058 0.053 0.0466
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.0013 0.0003 0.0003
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.003 0.0198 0.0198
Onchocerca volvulus 0.0724 0.8325 0.9288
Brugia malayi jmjC domain containing protein 0.0019 0.0067 0.0047
Schistosoma mansoni lar interacting protein (lip)-related protein 0.0077 0.0744 0.0681
Brugia malayi jmjC domain containing protein 0.0071 0.0674 0.0663
Loa Loa (eye worm) jmjC domain-containing protein 0.012 0.1258 0.1382
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0022 0.0109 0.0042
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0091 0.0913 0.0914
Echinococcus granulosus histone lysine methyltransferase setb 0.0091 0.0913 0.0912
Plasmodium vivax SET domain protein, putative 0.0091 0.0913 1
Schistosoma mansoni hypothetical protein 0.0077 0.0744 0.0681
Echinococcus multilocularis lysine specific demethylase 5A 0.0071 0.0674 0.0675
Loa Loa (eye worm) hypothetical protein 0.0019 0.0067 0.0074
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0171 0.0188
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.003 0.0198 0.5
Schistosoma mansoni hypothetical protein 0.0077 0.0744 0.0681
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.007 0.0023
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0913 0.0852
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0067 0.0074
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0067 0.0067
Trypanosoma cruzi trypanothione reductase, putative 0.0087 0.0861 0.6471
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.1295 0.1558
Brugia malayi sterile alpha and TIR motif containing protein 1 isoform a 0.0077 0.0744 0.0734
Schistosoma mansoni lip-related protein (liprin) alpha 0.0077 0.0744 0.0681
Brugia malayi Thioredoxin reductase 0.0087 0.0861 0.0853
Trypanosoma brucei poly(adp-ribose) polymerase 0.0124 0.1295 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.003 0.0198 0.5
Echinococcus multilocularis SAM domain containing protein 0.0077 0.0744 0.0745
Loa Loa (eye worm) hypothetical protein 0.0019 0.007 0.0077
Echinococcus granulosus phd:f box containing protein 0.0019 0.0067 0.0064
Echinococcus multilocularis sterile alpha and tir motif containing protein 0.0077 0.0744 0.0745
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.003 0.0198 0.1068
Echinococcus multilocularis lamin dm0 0.0028 0.0171 0.0171
Loa Loa (eye worm) glutathione reductase 0.0087 0.0861 0.0946
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0744 0.0895
Entamoeba histolytica poly(ADP-ribose) polymerase, putative 0.0124 0.1295 0.5
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0091 0.0913 0.0852
Brugia malayi jmjC domain containing protein 0.0019 0.0067 0.0047
Echinococcus granulosus stromal interaction molecule 1 0.0077 0.0744 0.0742
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.003 0.0198 0.1068
Echinococcus multilocularis jumonji domain containing protein 0.0081 0.0798 0.0799
Loa Loa (eye worm) hypothetical protein 0.0124 0.1295 0.1423
Onchocerca volvulus Tankyrase homolog 0.0777 0.8949 1
Entamoeba histolytica hypothetical protein 0.0124 0.1295 0.5
Entamoeba histolytica zinc finger protein, putative 0.0124 0.1295 0.5
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0191 0.2085 0.2085
Echinococcus granulosus poly adp ribose polymerase 2 0.0124 0.1295 0.1294
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0744 0.0895
Brugia malayi Tnks protein 0.0857 0.9879 1
Plasmodium falciparum glutathione reductase 0.0087 0.0861 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.003 0.0198 0.1068
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.1295 0.1558
Mycobacterium ulcerans flavoprotein disulfide reductase 0.003 0.0198 0.5
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0091 0.0913 0.0914
Loa Loa (eye worm) hypothetical protein 0.005 0.0429 0.0472
Echinococcus multilocularis liprin alpha 2 0.0077 0.0744 0.0745
Loa Loa (eye worm) hypothetical protein 0.0027 0.0165 0.0182
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0913 0.0852
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0109 0.009
Loa Loa (eye worm) tnks protein 0.079 0.9101 1
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.003 0.0198 0.155
Echinococcus multilocularis tankyrase 0.0866 0.9986 1
Loa Loa (eye worm) hypothetical protein 0.0655 0.7515 0.8257
Mycobacterium tuberculosis Probable oxidoreductase 0.022 0.242 1
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.003 0.0198 0.0132
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0067 0.0064
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0635 0.7283 0.8002
Schistosoma mansoni sarm1 0.0077 0.0744 0.0681
Loa Loa (eye worm) hypothetical protein 0.0013 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0077 0.0744 0.0817
Schistosoma mansoni jumonji/arid domain-containing protein 0.0071 0.0674 0.0611
Brugia malayi PHD-finger family protein 0.0019 0.007 0.005
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0171 0.0153
Schistosoma mansoni lamin 0.0028 0.0171 0.0105
Echinococcus granulosus SAM domain containing protein 0.0077 0.0744 0.0742
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0003 0.0003
Leishmania major acetoin dehydrogenase e3 component-like protein 0.003 0.0198 0.1651
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0191 0.2085 0.2088
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0198 0.1068
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.003 0.0198 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0124 0.1295 0.1558
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0019 0.007 0.0035
Plasmodium falciparum glutathione reductase 0.003 0.0198 0.1651
Brugia malayi jmjC domain containing protein 0.0019 0.0067 0.0047
Schistosoma mansoni hypothetical protein 0.0077 0.0744 0.0681
Leishmania major dihydrolipoamide dehydrogenase, putative 0.003 0.0198 0.1651
Echinococcus multilocularis liprin beta 1 0.0077 0.0744 0.0745
Brugia malayi intermediate filament protein 0.0028 0.0171 0.0153
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0019 0.0067 0.0067
Echinococcus granulosus lysine specific demethylase 5A 0.0071 0.0674 0.0672
Trypanosoma cruzi poly(ADP-ribose) polymerase, putative 0.0124 0.1295 1
Trypanosoma brucei trypanothione reductase 0.0087 0.0861 0.6471
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0198 0.2162 0.8837
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0744 0.0895
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.003 0.0198 0.5
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.003 0.0198 0.1068
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0198 0.2162 0.8837
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0019 0.0067 0.0064
Brugia malayi Pre-SET motif family protein 0.0635 0.7283 0.7367
Entamoeba histolytica hypothetical protein 0.0124 0.1295 0.5
Brugia malayi AF-10 protein 0.0019 0.007 0.005
Schistosoma mansoni intermediate filament proteins 0.0028 0.0171 0.0105
Plasmodium falciparum phd finger protein, putative 0.0058 0.053 0.5827

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.