Detailed information for compound 806382

Basic information

Technical information
  • TDR Targets ID: 806382
  • Name: N-(2,5-dimethoxyphenyl)-1,4-dimethyl-2,3-diox oquinoxaline-6-sulfonamide
  • MW: 405.425 | Formula: C18H19N3O6S
  • H donors: 1 H acceptors: 4 LogP: 1.28 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1NS(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C)OC
  • InChi: 1S/C18H19N3O6S/c1-20-14-7-6-12(10-15(14)21(2)18(23)17(20)22)28(24,25)19-13-9-11(26-3)5-8-16(13)27-4/h5-10,19H,1-4H3
  • InChiKey: ZPWHOZGZTJAHDA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2,5-dimethoxyphenyl)-1,4-dimethyl-2,3-dioxo-quinoxaline-6-sulfonamide
  • N-(2,5-dimethoxyphenyl)-1,4-dimethyl-2,3-dioxo-6-quinoxalinesulfonamide
  • N-(2,5-dimethoxyphenyl)-2,3-diketo-1,4-dimethyl-quinoxaline-6-sulfonamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus roundabout 2 0.0045 0.0074 0.0058
Brugia malayi hypothetical protein 0.0058 0.0304 0.0413
Trichomonas vaginalis AGC family protein kinase 0.0062 0.039 0.1992
Schistosoma mansoni amine GPCR 0.0058 0.0304 0.0503
Onchocerca volvulus 0.0058 0.0304 0.1016
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0058 0.0304 0.0413
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0052 0.0209 0.0194
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0058 0.0304 0.0368
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0058 0.0304 0.0368
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0131 0.1604 0.203
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0058 0.0304 0.0503
Echinococcus granulosus tyrosine protein kinase Fyn 0.0131 0.1604 0.1591
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0058 0.0304 0.0372
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0304 0.0289
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0084
Loa Loa (eye worm) G-protein coupled receptor 0.0058 0.0304 0.0372
Brugia malayi Serotonin receptor 0.0058 0.0304 0.0413
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0247 0.3672 0.4717
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0131 0.1604 0.203
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Onchocerca volvulus 0.0058 0.0304 0.1016
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0131 0.1604 0.203
Echinococcus granulosus neuropeptides capa receptor 0.0058 0.0304 0.0289
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0061 0.0371 0.0454
Schistosoma mansoni hypothetical protein 0.0069 0.0506 0.0856
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0131 0.1604 0.203
Onchocerca volvulus 0.0058 0.0304 0.1016
Echinococcus granulosus insulin receptor 0.0248 0.3692 0.3682
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0304 0.0368
Echinococcus multilocularis mitogen activated protein kinase 11 0.0135 0.1675 0.2121
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Schistosoma mansoni neuropeptide receptor 0.0058 0.0304 0.0503
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0042 0.0033 0.0018
Entamoeba histolytica protein kinase domain containing protein 0.0062 0.039 0.2036
Schistosoma mansoni biogenic amine receptor 0.0058 0.0304 0.0503
Schistosoma mansoni tyrosine kinase 0.007 0.0526 0.089
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0169 0.2294 0.2939
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0113 0.1287 0.1274
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0113 0.1287 0.1626
Brugia malayi hypothetical protein 0.0058 0.0304 0.0413
Echinococcus multilocularis neuropeptide Y receptor 0.0058 0.0304 0.0368
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0292 0.4474 0.4465
Schistosoma mansoni serine/threonine protein kinase 0.0169 0.2294 0.3973
Schistosoma mansoni vesicular amine transporter 0.0061 0.0371 0.062
Echinococcus multilocularis neuropeptide receptor A26 0.0058 0.0304 0.0368
Schistosoma mansoni protein kinase 0.0062 0.039 0.0653
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0058 0.0304 0.0368
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0304 0.0289
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0131 0.1604 0.1591
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.1096 1
Loa Loa (eye worm) neuropeptide F receptor 0.0058 0.0304 0.0372
Loa Loa (eye worm) hypothetical protein 0.0152 0.198 0.2535
Brugia malayi Protein kinase domain containing protein 0.0052 0.0209 0.0277
Echinococcus multilocularis c src tyrosine kinase 0.007 0.0526 0.0652
Schistosoma mansoni neuropeptide f receptor 76f 0.0058 0.0304 0.0503
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Schistosoma mansoni biogenic amine (5HT) receptor 0.0058 0.0304 0.0503
Schistosoma mansoni tyrosine kinase 0.0131 0.1604 0.2771
Echinococcus multilocularis serotonin receptor 0.0058 0.0304 0.0368
Onchocerca volvulus 0.0052 0.0209 0.0699
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0266 0.4005 0.5098
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0058 0.0304 0.0413
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0054 0.0235 0.022
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Brugia malayi neuropeptide F receptor 0.0058 0.0304 0.0413
Echinococcus granulosus sex peptide receptor 0.0058 0.0304 0.0289
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0304 0.0289
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0084 0.0777 0.0973
Echinococcus granulosus neuropeptide receptor A26 0.0058 0.0304 0.0289
Schistosoma mansoni serine/threonine protein kinase 0.0191 0.2677 0.4641
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0208 0.2979 0.3787
Echinococcus granulosus neuropeptides capa receptor 0.0058 0.0304 0.0289
Echinococcus granulosus tm gpcr rhodopsin 0.0058 0.0304 0.0289
Echinococcus multilocularis neuropeptide receptor 0.0058 0.0304 0.0368
Entamoeba histolytica tyrosin kinase, putative 0.0059 0.0328 0.1343
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0058 0.0304 0.0503
Echinococcus granulosus tyrosine protein kinase shark 0.0052 0.0209 0.0194
Echinococcus granulosus twitchin 0.0079 0.0686 0.0672
Echinococcus multilocularis neuropeptide FF receptor 2 0.0058 0.0304 0.0368
Echinococcus multilocularis roundabout 2 0.0045 0.0074 0.0075
Echinococcus granulosus mitogen activated protein kinase 14 0.0135 0.1675 0.1662
Schistosoma mansoni nephrin 0.0045 0.0074 0.0102
Echinococcus granulosus neuropeptide FF receptor 2 0.0058 0.0304 0.0289
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0304 0.0289
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0058 0.0304 0.0368
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Loa Loa (eye worm) sema domain-containing protein 0.0069 0.0506 0.0633
Schistosoma mansoni biogenic amine receptor 0.0058 0.0304 0.0503
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0062 0.039 0.2036
Brugia malayi serine/threonine protein kinase 6 0.0062 0.039 0.0536
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0084
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0131 0.1604 0.203
Schistosoma mansoni tyrosine kinase 0.0248 0.3692 0.6411
Onchocerca volvulus 0.0058 0.0304 0.1016
Echinococcus multilocularis allatostatin A receptor 0.0058 0.0304 0.0368
Loa Loa (eye worm) STE/STE20/SLK protein kinase 0.0169 0.2295 0.294
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Loa Loa (eye worm) hypothetical protein 0.0069 0.0506 0.0633
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0052 0.0209 0.0247
Loa Loa (eye worm) AUR protein kinase 0.0062 0.039 0.0483
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Echinococcus multilocularis neuroglian 0.0075 0.0612 0.0763
Brugia malayi hypothetical protein 0.0069 0.0506 0.0703
Brugia malayi map kinase activated protein kinase protein 2 0.0191 0.2677 0.3811
Brugia malayi GnHR receptor homolog 0.0058 0.0304 0.0413
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0058 0.0304 0.0289
Brugia malayi putative neuropeptide receptor NPR1 0.0058 0.0304 0.0413
Brugia malayi G-protein coupled receptor 0.0058 0.0304 0.0413
Brugia malayi putative neuropeptide receptor 0.0058 0.0304 0.0413
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0058 0.0304 0.0413
Schistosoma mansoni protein kinase 0.0169 0.2295 0.3975
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0042 0.0033 0.0022
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0058 0.0304 0.1016
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Brugia malayi P38 map kinase family protein 2 0.0135 0.1675 0.2377
Loa Loa (eye worm) hypothetical protein 0.0061 0.0371 0.0458
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0131 0.1604 0.203
Echinococcus granulosus g protein coupled receptor 0.0058 0.0304 0.0289
Loa Loa (eye worm) sema domain-containing protein 0.0069 0.0506 0.0633
Schistosoma mansoni tyrosine kinase 0.0263 0.3963 0.6885
Schistosoma mansoni cell adhesion molecule 0.0045 0.0074 0.0102
Echinococcus granulosus neuropeptide receptor 0.0058 0.0304 0.0289
Schistosoma mansoni hypothetical protein 0.0058 0.0304 0.0503
Brugia malayi AKH receptor 0.0058 0.0304 0.0413
Brugia malayi RE15519p 0.0058 0.0304 0.0413
Trichomonas vaginalis AGC family protein kinase 0.0062 0.039 0.1992
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0266 0.4005 0.3995
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Loa Loa (eye worm) TK protein kinase 0.0089 0.087 0.1102
Echinococcus granulosus 7TM GPCR rhodopsin 0.0058 0.0304 0.0289
Echinococcus granulosus neuropeptide receptor 0.0058 0.0304 0.0289
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0058 0.0304 0.0503
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0061 0.0371 0.062
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0135 0.1675 1
Echinococcus granulosus tyrosine protein kinase Fyn 0.0131 0.1604 0.1591
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.1096 1
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0209 0.025
Echinococcus multilocularis STE20 serine:threonine protein kinase 0.0481 0.784 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0304 0.0368
Onchocerca volvulus 0.0058 0.0304 0.1016
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0191 0.2677 0.3433
Loa Loa (eye worm) neuropeptide F receptor 0.0058 0.0304 0.0372
Schistosoma mansoni cell adhesion molecule 0.0045 0.0074 0.0102
Schistosoma mansoni tyrosine kinase 0.0056 0.0272 0.0446
Onchocerca volvulus 0.0058 0.0304 0.1016
Loa Loa (eye worm) AUR protein kinase 0.0062 0.039 0.0483
Echinococcus granulosus tachykinin peptides receptor 99D 0.0058 0.0304 0.0289
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0058 0.0304 0.0368
Brugia malayi ephrin receptor 1 precursor 0.0055 0.0267 0.036
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0058 0.0304 0.0503
Echinococcus multilocularis G protein coupled receptor 139 0.0058 0.0304 0.0368
Echinococcus granulosus aurora kinase A 0.0062 0.039 0.0375
Loa Loa (eye worm) hypothetical protein 0.0057 0.029 0.0354
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0191 0.2677 0.3401
Echinococcus multilocularis protein kinase shaggy 0.0054 0.0235 0.0281
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Echinococcus granulosus dro:myosuppressin receptor 0.0058 0.0304 0.0289
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0049 0.0148 0.0171
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0209 0.025
Onchocerca volvulus 0.0054 0.0242 0.0808
Schistosoma mansoni hypothetical protein 0.0058 0.0304 0.0503
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0058 0.0304 0.0413
Entamoeba histolytica serine/threonine protein kinase, putative 0.0102 0.1096 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0058 0.0304 0.0372
Schistosoma mansoni neuroglian 0.0045 0.0074 0.0102
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0235 0.0239
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0304 0.0503
Onchocerca volvulus 0.0054 0.0235 0.0786
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0045 0.0074 0.0075
Schistosoma mansoni amine GPCR 0.0058 0.0304 0.0503
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0209 0.025
Loa Loa (eye worm) hypothetical protein 0.0079 0.0684 0.0862
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0052 0.0209 0.0247
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0328 0.1343
Schistosoma mansoni kinase 0.0054 0.0237 0.0386
Giardia lamblia Aurora kinase 0.0062 0.039 0.1796
Echinococcus granulosus ephrin type A receptor 4 A 0.0099 0.1041 0.1027
Echinococcus granulosus fmrfamide receptor 0.0058 0.0304 0.0289
Brugia malayi Tachykinin-like peptides receptor 99D 0.0058 0.0304 0.0413
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0304 0.0368
Echinococcus multilocularis somatostatin receptor 0.0058 0.0304 0.0368
Echinococcus granulosus STE20 serine:threonine protein kinase 0.0481 0.784 0.7837
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Schistosoma mansoni tyrosine kinase 0.0292 0.4474 0.7775
Onchocerca volvulus 0.0058 0.0304 0.1016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0304 0.0368
Brugia malayi Melatonin receptor type 1A 0.0058 0.0304 0.0413
Echinococcus granulosus tyrosine protein kinase ABL1 0.0052 0.0209 0.0194
Brugia malayi hypothetical protein 0.0058 0.0304 0.0413
Echinococcus multilocularis neuropeptide s receptor 0.0058 0.0304 0.0368
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Brugia malayi Sema domain containing protein 0.0069 0.0506 0.0703
Brugia malayi plexin A 0.0182 0.2517 0.3583
Echinococcus granulosus defective proboscis extension response 0.0061 0.0371 0.0356
Onchocerca volvulus 0.0052 0.0209 0.0699
Brugia malayi SH2 domain containing protein 0.0052 0.0209 0.0277
Onchocerca volvulus 0.0152 0.198 0.662
Schistosoma mansoni adenoreceptor 0.0058 0.0304 0.0503
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0062 0.039 0.0375
Echinococcus multilocularis neuroglian 0.0045 0.0074 0.0075
Echinococcus granulosus tm gpcr rhodopsin 0.0058 0.0304 0.0289
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.1096 1
Loa Loa (eye worm) hypothetical protein 0.0069 0.0506 0.0633
Loa Loa (eye worm) hypothetical protein 0.0069 0.0506 0.0633
Brugia malayi serine/threonine-protein kinase 6 0.0062 0.039 0.0536
Loa Loa (eye worm) plexin A 0.0182 0.2517 0.3227
Schistosoma mansoni tyrosine kinase 0.0263 0.3963 0.6885
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0102 0.1096 0.1381
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0058 0.0304 0.0372
Brugia malayi Tyrosine-protein kinase abl-1 0.007 0.0526 0.0731
Loa Loa (eye worm) TK/EGFR protein kinase 0.0364 0.575 0.7398
Brugia malayi hypothetical protein 0.0058 0.0304 0.0413
Schistosoma mansoni opsin-like receptor 0.0058 0.0304 0.0503
Echinococcus granulosus 7tm_1 domain containing protein 0.0058 0.0304 0.0289
Brugia malayi serine/threonine-protein kinase plk-2 0.0102 0.1096 0.1548
Echinococcus granulosus neuroglian 0.0045 0.0074 0.0058
Loa Loa (eye worm) hypothetical protein 0.0477 0.7766 1
Echinococcus granulosus plexin a4 0.0182 0.2517 0.2505
Echinococcus granulosus biogenic amine 5HT receptor 0.0058 0.0304 0.0289
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.1096 1
Echinococcus granulosus hypothetical protein 0.0058 0.0304 0.0289
Echinococcus granulosus neuropeptide Y receptor 0.0058 0.0304 0.0289
Onchocerca volvulus 0.0058 0.0304 0.1016
Brugia malayi protein-tyrosine kinase 0.0113 0.1287 0.1822
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Echinococcus multilocularis ephrin type A receptor 4 A 0.0099 0.1041 0.131
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0209 0.025
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0058 0.0304 0.0368
Echinococcus multilocularis tyrosine protein kinase Srms 0.0113 0.1287 0.1626
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0434 0.6997 0.9008
Brugia malayi Dopamine receptor protein 1 0.0058 0.0304 0.0413
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0304 0.0289
Echinococcus multilocularis fmrfamide receptor 0.0058 0.0304 0.0368
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0062 0.039 0.2036
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0209 0.025
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0169 0.2294 0.2282
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0058 0.0304 0.0372
Entamoeba histolytica protein kinase, putative 0.0062 0.039 0.2036
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0054 0.0235 0.0383
Onchocerca volvulus 0.0058 0.0304 0.1016
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0304 0.0289
Echinococcus multilocularis tyrosine protein kinase HCK 0.0089 0.087 0.1092
Brugia malayi Serotonin receptor 0.0058 0.0304 0.0413
Echinococcus multilocularis G-protein coupled receptor, putative 0.0058 0.0304 0.0368
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0058 0.0304 0.0503
Brugia malayi Immunoglobulin I-set domain containing protein 0.0247 0.3672 0.5237
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0058 0.0304 0.0503
Echinococcus multilocularis tyrosine protein kinase shark 0.0052 0.0209 0.0247
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0131 0.1604 0.1591
Schistosoma mansoni hypothetical protein 0.0058 0.0304 0.0503
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0209 0.025
Schistosoma mansoni hypothetical protein 0.0054 0.0242 0.0394
Loa Loa (eye worm) hypothetical protein 0.0044 0.0069 0.0069
Schistosoma mansoni amine GPCR 0.0058 0.0304 0.0503
Loa Loa (eye worm) hypothetical protein 0.0045 0.0074 0.0075
Schistosoma mansoni opsin-like receptor 0.0058 0.0304 0.0503
Onchocerca volvulus 0.0058 0.0304 0.1016
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0304 0.0368
Loa Loa (eye worm) hypothetical protein 0.0069 0.0506 0.0633
Echinococcus multilocularis plexin a4 0.0182 0.2517 0.3197
Brugia malayi hypothetical protein 0.0058 0.0304 0.0413
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0131 0.1604 0.203
Schistosoma mansoni tyrosine kinase 0.0131 0.1604 0.2771
Entamoeba histolytica protein kinase, putative 0.0062 0.039 0.2036
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0304 0.0368
Echinococcus granulosus G protein coupled receptor 139 0.0058 0.0304 0.0289
Echinococcus granulosus epidermal growth factor receptor 0.0292 0.4474 0.4465
Brugia malayi larval opioid receptor 0.0058 0.0304 0.0413
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0033 0.0025
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0058 0.0304 0.0289
Echinococcus multilocularis roundabout 2 0.0045 0.0074 0.0075
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0304 0.0503
Loa Loa (eye worm) hypothetical protein 0.0079 0.0684 0.0862
Schistosoma mansoni neuropeptide receptor 0.0058 0.0304 0.0503
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0058 0.0304 0.0503
Echinococcus granulosus g protein coupled receptor 0.0058 0.0304 0.0289
Loa Loa (eye worm) hypothetical protein 0.0074 0.0601 0.0756
Schistosoma mansoni tyrosine kinase 0.0248 0.3692 0.6411
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0045 0.0074 0.0075
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0304 0.0503
Loa Loa (eye worm) TK protein kinase 0.0113 0.1287 0.1641
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0062 0.039 0.2036
Echinococcus granulosus roundabout 2 0.0106 0.1164 0.115
Brugia malayi Protein kinase domain containing protein 0.0169 0.2294 0.3263
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0209 0.025
Brugia malayi G protein-coupled receptor 0.0058 0.0304 0.0413
Brugia malayi G-protein coupled receptor 0.0058 0.0304 0.0413
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0045 0.0074 0.0102
Echinococcus multilocularis semaphorin 5B 0.0069 0.0506 0.0627
Echinococcus multilocularis epidermal growth factor receptor 0.0364 0.575 0.7328
Schistosoma mansoni alpha-1 adrenergic receptor 0.0058 0.0304 0.0503
Echinococcus granulosus semaphorin 5B 0.0069 0.0506 0.0491
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0058 0.0304 0.0289
Loa Loa (eye worm) AUR protein kinase 0.0062 0.039 0.0483
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0209 0.025
Echinococcus multilocularis tyrosine kinase 0.0052 0.0209 0.0247
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.1096 1
Schistosoma mansoni serine/threonine protein kinase 0.0062 0.039 0.0653
Echinococcus multilocularis hypothetical protein 0.0069 0.0506 0.0627
Echinococcus multilocularis insulin receptor 0.0248 0.3692 0.4698
Schistosoma mansoni biogenic amine (5HT) receptor 0.0058 0.0304 0.0503
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0062 0.039 0.0478
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0135 0.1675 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Onchocerca volvulus 0.0058 0.0304 0.1016
Echinococcus multilocularis 0.0186 0.2585 0.3284
Echinococcus granulosus hemicentin 1 0.005 0.0167 0.0152
Brugia malayi hypothetical protein 0.0069 0.0506 0.0703
Echinococcus multilocularis dro:myosuppressin receptor 0.0058 0.0304 0.0368
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Schistosoma mansoni neuropeptide receptor 0.0058 0.0304 0.0503
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Echinococcus granulosus neuroglian 0.0075 0.0612 0.0598
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0061 0.0371 0.062
Brugia malayi Protein kinase domain containing protein 0.0434 0.6997 1
Onchocerca volvulus Basement membrane proteoglycan homolog 0.005 0.0167 0.0559
Echinococcus multilocularis Immunoglobulin 0.0061 0.0371 0.0454
Echinococcus granulosus tyrosine kinase 0.0113 0.1287 0.1274
Schistosoma mansoni nephrin 0.0092 0.0925 0.1586
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0058 0.0304 0.0368
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0102 0.1096 0.1082
Brugia malayi Protein kinase domain containing protein 0.0052 0.0209 0.0277
Onchocerca volvulus 0.0058 0.0304 0.1016
Brugia malayi Immunoglobulin I-set domain containing protein 0.0079 0.0684 0.0957
Brugia malayi Furin-like cysteine rich region family protein 0.0364 0.575 0.8213
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0304 0.0503
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0074 0.0084
Brugia malayi Dopamine receptor protein 2 0.0058 0.0304 0.0413
Trypanosoma cruzi polo-like protein kinase, putative 0.0102 0.1096 0.5979
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0102 0.1096 0.5979
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0058 0.0304 0.0368
Loa Loa (eye worm) hypothetical protein 0.0111 0.1257 0.1602
Echinococcus granulosus tyrosine protein kinase Src42A 0.0131 0.1604 0.1591
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0304 0.0503
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0058 0.0304 0.0368
Schistosoma mansoni serine/threonine protein kinase 0.0047 0.0108 0.0162
Onchocerca volvulus 0.0057 0.029 0.097
Echinococcus granulosus epidermal growth factor receptor 0.0364 0.575 0.5743
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Echinococcus granulosus tyrosine protein kinase Lyn 0.0135 0.1678 0.1665
Brugia malayi ORL1-like opioid receptor 0.0058 0.0304 0.0413
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0131 0.1604 0.203
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Schistosoma mansoni amine GPCR 0.0058 0.0304 0.0503
Loa Loa (eye worm) TYRA-2 protein 0.0058 0.0304 0.0372
Brugia malayi G protein-coupled receptor F59B2.13 0.0058 0.0304 0.0413
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Brugia malayi hypothetical protein 0.0058 0.0304 0.0413
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0304 0.0368
Echinococcus granulosus peptide allatostatin:somatostatin 0.0058 0.0304 0.0289
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0058 0.0304 0.0503
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0135 0.1675 0.2141
Echinococcus multilocularis epidermal growth factor receptor 0.0292 0.4474 0.5697
Onchocerca volvulus 0.0058 0.0304 0.1016
Echinococcus granulosus contactin 0.0067 0.048 0.0465
Loa Loa (eye worm) hypothetical protein 0.0069 0.0506 0.0633
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Leishmania major protein kinase, putative 0.0062 0.039 0.1074
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0058 0.0304 0.0503
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0135 0.1675 1
Echinococcus granulosus tyrosine protein kinase HCK 0.0089 0.087 0.0856
Brugia malayi Protein kinase domain containing protein 0.0052 0.0209 0.0277
Echinococcus granulosus tyrosine protein kinase Fyn 0.0131 0.1604 0.1591
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0058 0.0304 0.0289
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0209 0.025
Echinococcus multilocularis g-protein coupled receptor 0.0058 0.0304 0.0368
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0045 0.0074 0.0075
Echinococcus multilocularis neuropeptides capa receptor 0.0058 0.0304 0.0368
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Echinococcus granulosus biogenic amine 5HT receptor 0.0058 0.0304 0.0289
Loa Loa (eye worm) TK/EPH protein kinase 0.0101 0.1077 0.137
Brugia malayi hypothetical protein 0.0079 0.0684 0.0957
Brugia malayi intracellular kinase 0.0054 0.0235 0.0314
Loa Loa (eye worm) TK/ROR protein kinase 0.0042 0.0033 0.0023
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Echinococcus granulosus orexin receptor type 2 0.0058 0.0304 0.0289
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0131 0.1604 0.203
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0304 0.0503
Echinococcus multilocularis tyrosine protein kinase Blk 0.0113 0.1287 0.1626
Echinococcus granulosus somatostatin receptor 0.0058 0.0304 0.0289
Schistosoma mansoni tyrosine kinase 0.019 0.2662 0.4615
Schistosoma mansoni cell adhesion molecule 0.0092 0.0922 0.1581
Brugia malayi Sema domain containing protein 0.0069 0.0506 0.0703
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0058 0.0304 0.0372
Schistosoma mansoni opsin-like receptor 0.0058 0.0304 0.0503
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0045 0.0074 0.0058
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.0235 0.0239
Echinococcus multilocularis neuropeptide Y receptor 0.0058 0.0304 0.0368
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.007 0.0526 0.089
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0058 0.0304 0.0368
Echinococcus granulosus allatostatin A receptor 0.0058 0.0304 0.0289
Brugia malayi Fibronectin type III domain containing protein 0.0079 0.0684 0.0957
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0045 0.0074 0.0075
Brugia malayi hypothetical protein 0.0052 0.0209 0.0277
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0169 0.2294 0.7668
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.1096 0.1884
Brugia malayi Protein kinase domain containing protein 0.0052 0.0209 0.0277
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0062 0.039 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0058 0.0304 0.0368
Echinococcus multilocularis serotonin receptor 0.0058 0.0304 0.0368
Onchocerca volvulus Neuropeptide F receptor homolog 0.0058 0.0304 0.1016
Trichomonas vaginalis AGC family protein kinase 0.0062 0.039 0.1992
Echinococcus multilocularis g protein coupled receptor 0.0058 0.0304 0.0368
Trypanosoma cruzi aurora B kinase, putative 0.0062 0.039 0.1074
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0304 0.0503
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0054 0.0235 0.0283
Schistosoma mansoni biogenic amine receptor 0.0058 0.0304 0.0503
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0169 0.2294 0.2939
Echinococcus granulosus Immunoglobulin 0.0061 0.0371 0.0356
Echinococcus multilocularis g protein coupled receptor 0.0058 0.0304 0.0368
Echinococcus granulosus tm gpcr rhodopsin 0.0058 0.0304 0.0289
Onchocerca volvulus 0.0058 0.0304 0.1016
Brugia malayi hypothetical protein 0.0058 0.0304 0.0413
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0058 0.0304 0.0413
Onchocerca volvulus 0.0052 0.0209 0.0699
Brugia malayi hypothetical protein 0.0058 0.0304 0.0413
Entamoeba histolytica protein kinase, putative 0.0054 0.0235 0.0293
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0054 0.0235 0.0281
Brugia malayi serine/threonine kinase 12 0.0062 0.039 0.0536
Echinococcus multilocularis fmrfamide receptor 0.0058 0.0304 0.0368
Echinococcus granulosus neuropeptide s receptor 0.0058 0.0304 0.0289
Toxoplasma gondii aurora kinase 0.0062 0.039 1
Entamoeba histolytica protein kinase , putative 0.0062 0.039 0.2036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0304 0.0503
Entamoeba histolytica protein kinase domain containing protein 0.0054 0.0235 0.0293
Echinococcus granulosus g protein coupled receptor 0.0058 0.0304 0.0289
Plasmodium falciparum serine/threonine protein kinase, putative 0.0062 0.039 1
Schistosoma mansoni hypothetical protein 0.0069 0.0506 0.0856
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Schistosoma mansoni neuropeptide receptor 0.0058 0.0304 0.0503
Onchocerca volvulus 0.0144 0.1833 0.6128
Brugia malayi neuropeptide F receptor 0.0058 0.0304 0.0413
Loa Loa (eye worm) hypothetical protein 0.0079 0.0684 0.0862
Echinococcus multilocularis mitogen activated protein kinase 11 0.0135 0.1675 0.2121
Schistosoma mansoni hypothetical protein 0.0083 0.0755 0.129
Brugia malayi Dopamine receptor 0.0058 0.0304 0.0413
Entamoeba histolytica protein kinase, putative 0.0089 0.087 0.7449
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Echinococcus multilocularis neuropeptides capa receptor 0.0058 0.0304 0.0368
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0058 0.0304 0.0289
Loa Loa (eye worm) hypothetical protein 0.0069 0.0506 0.0633
Echinococcus multilocularis g protein coupled receptor 0.0058 0.0304 0.0368
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0058 0.0304 0.0503
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0058 0.0304 0.0289
Schistosoma mansoni amine GPCR 0.0058 0.0304 0.0503
Brugia malayi SH2 domain containing protein 0.0052 0.0209 0.0277
Onchocerca volvulus 0.0052 0.0209 0.0699
Echinococcus granulosus protein kinase shaggy 0.0054 0.0235 0.022
Brugia malayi Protein kinase domain containing protein 0.0248 0.3692 0.5266
Echinococcus multilocularis orexin receptor type 2 0.0058 0.0304 0.0368
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0058 0.0304 0.0368
Schistosoma mansoni tyrosine kinase 0.0052 0.0209 0.0338
Onchocerca volvulus 0.0069 0.0506 0.1692
Echinococcus multilocularis mitogen activated protein kinase 14 0.0135 0.1675 0.2121
Schistosoma mansoni tyrosine kinase 0.007 0.0526 0.089
Echinococcus granulosus roundabout 2 0.0045 0.0074 0.0058
Echinococcus granulosus alpha 1A adrenergic receptor 0.0058 0.0304 0.0289
Echinococcus granulosus tyrosine protein kinase Src42A 0.0084 0.0777 0.0763
Loa Loa (eye worm) hypothetical protein 0.0088 0.0851 0.1078
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Loa Loa (eye worm) TK protein kinase 0.0042 0.0033 0.0023
Echinococcus granulosus semaphorin 1A 0.0069 0.0506 0.0491
Schistosoma mansoni tyrosine kinase 0.0364 0.575 1
Onchocerca volvulus Tyrosine kinase homolog 0.0209 0.2991 1
Schistosoma mansoni semaphorin 5-related 0.0069 0.0506 0.0856
Onchocerca volvulus 0.0052 0.0209 0.0699
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Schistosoma mansoni ephrin receptor 0.0046 0.0104 0.0155
Brugia malayi Plexin repeat family protein 0.0152 0.198 0.2814
Loa Loa (eye worm) hypothetical protein 0.0083 0.0755 0.0955
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Brugia malayi sulfakinin receptor protein 0.0058 0.0304 0.0413
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Loa Loa (eye worm) hypothetical protein 0.0075 0.0609 0.0766
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0102 0.1096 0.1394
Loa Loa (eye worm) G-protein coupled receptor 0.0058 0.0304 0.0372
Brugia malayi Protein kinase domain containing protein 0.0169 0.2295 0.3264
Loa Loa (eye worm) hypothetical protein 0.0052 0.0209 0.025
Echinococcus multilocularis neuropeptide receptor 0.0058 0.0304 0.0368
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0058 0.0304 0.0503
Brugia malayi follicle stimulating hormone receptor 0.0058 0.0304 0.0413
Echinococcus granulosus tyrosine protein kinase Srms 0.0052 0.0209 0.0194
Brugia malayi hypothetical protein 0.0058 0.0304 0.0413
Trypanosoma brucei aurora B kinase 0.0062 0.039 0.1074
Echinococcus granulosus mitogen activated protein kinase 11 0.0135 0.1675 0.1662
Loa Loa (eye worm) hypothetical protein 0.0062 0.0375 0.0464
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0058 0.0304 0.0368
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0058 0.0304 0.0503
Loa Loa (eye worm) melatonin receptor type 1A 0.0058 0.0304 0.0372
Schistosoma mansoni neuropeptide F-like receptor 0.0058 0.0304 0.0503
Onchocerca volvulus 0.0058 0.0304 0.1016
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0169 0.2294 0.2912
Loa Loa (eye worm) SRC-1 0.0131 0.1604 0.205
Brugia malayi Protein kinase domain containing protein 0.0103 0.1112 0.157
Loa Loa (eye worm) TK/ABL protein kinase 0.0052 0.0209 0.025
Echinococcus granulosus tyrosine kinase 0.0052 0.0209 0.0194
Brugia malayi SRC-1 0.0131 0.1604 0.2275
Onchocerca volvulus Serine\/threonine kinase homolog 0.0102 0.1096 0.3664
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0191 0.2677 0.2665
Echinococcus granulosus c src tyrosine kinase 0.007 0.0526 0.0511
Echinococcus multilocularis mitogen activated protein kinase 14 0.0135 0.1675 0.2121
Echinococcus granulosus neuropeptide Y receptor 0.0058 0.0304 0.0289
Schistosoma mansoni neuropeptide F-like receptor 0.0058 0.0304 0.0503
Schistosoma mansoni titin 0.005 0.0167 0.0265
Loa Loa (eye worm) TK/FER protein kinase 0.0052 0.0209 0.025
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0058 0.0304 0.0503
Brugia malayi Protein kinase domain containing protein 0.0052 0.0209 0.0277
Echinococcus granulosus serotonin receptor 0.0058 0.0304 0.0289
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.1096 1
Schistosoma mansoni plexin 0.0083 0.0755 0.129
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0075 0.0609 0.0595
Echinococcus granulosus tyrosine protein kinase Blk 0.0113 0.1287 0.1274
Schistosoma mansoni tyrosine kinase 0.0263 0.3963 0.6885
Echinococcus granulosus rhodopsin orphan GPCR 0.0058 0.0304 0.0289
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0058 0.0304 0.0368
Loa Loa (eye worm) hypothetical protein 0.0061 0.0371 0.0458
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Trichomonas vaginalis AGC family protein kinase 0.0062 0.039 0.1992
Brugia malayi hypothetical protein 0.0058 0.0304 0.0413
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Trypanosoma cruzi polo-like protein kinase, putative 0.0102 0.1096 0.5979
Giardia lamblia Kinase, PLK 0.0102 0.1096 1
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0045 0.0074 0.0075
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0169 0.2294 0.3263
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0054 0.0235 0.0283
Echinococcus multilocularis tyrosine protein kinase Abl 0.007 0.0526 0.0652
Trichomonas vaginalis CAMK family protein kinase 0.0102 0.1096 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0058 0.0304 0.0503
Onchocerca volvulus 0.0058 0.0304 0.1016
Schistosoma mansoni hypothetical protein 0.0058 0.0304 0.0503
Schistosoma mansoni histamine h1 receptor 0.0058 0.0304 0.0503
Loa Loa (eye worm) hypothetical protein 0.0058 0.0304 0.0372
Echinococcus multilocularis sex peptide receptor 0.0058 0.0304 0.0368
Echinococcus multilocularis roundabout 2 0.0106 0.1164 0.1467
Echinococcus multilocularis Immunoglobulin 0.0061 0.0371 0.0454
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0058 0.0304 0.0368
Echinococcus granulosus tyrosine protein kinase Src64B 0.0131 0.1604 0.1591
Onchocerca volvulus 0.0052 0.0209 0.0699
Schistosoma mansoni plexin 0.0152 0.198 0.3427
Schistosoma mansoni growth hormone secretagogue receptor 0.0058 0.0304 0.0503
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0208 0.2979 0.2968
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0135 0.1675 1
Schistosoma mansoni ephrin receptor 0.0085 0.0801 0.1369
Trypanosoma brucei polo-like protein kinase 0.0102 0.1096 0.5979
Echinococcus multilocularis aurora kinase A 0.0062 0.039 0.0478
Loa Loa (eye worm) TK/INSR protein kinase 0.0248 0.3692 0.4743
Schistosoma mansoni tyrosine kinase 0.0292 0.4474 0.7775
Onchocerca volvulus 0.0058 0.0304 0.1016
Echinococcus granulosus g-protein coupled receptor 0.0058 0.0304 0.0289
Echinococcus multilocularis hemicentin 1 0.005 0.0167 0.0194
Schistosoma mansoni myosin xvIII 0.0058 0.0304 0.0503
Entamoeba histolytica protein kinase domain containing protein 0.0054 0.0235 0.0293

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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