TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 437.531 | Formula: C25H31N3O4
H donors: 1 H acceptors: 3 LogP: 3.26 Rotable bonds: 9
Rule of 5 violations (Lipinski): 1
SMILES: COc1cccc(c1)CN(C(=O)c1cn(cc(c1=O)C(=O)NC1CC1)C1CCCCC1)C
InChi: 1S/C25H31N3O4/c1-27(14-17-7-6-10-20(13-17)32-2)25(31)22-16-28(19-8-4-3-5-9-19)15-21(23(22)29)24(30)26-18-11-12-18/h6-7,10,13,15-16,18-19H,3-5,8-9,11-12,14H2,1-2H3,(H,26,30)
InChiKey: XUWCDPUFPYDIJI-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Brugia malayi	GnHR receptor homolog	0.0206	0.142	0.8473
Echinococcus multilocularis	beta tubulin	0.0023	0.0053	0.0053
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Toxoplasma gondii	target of rapamycin (TOR), putative	0.0033	0.0129	0.2093
Echinococcus multilocularis	Tubulin beta 2C chain	0.0023	0.0053	0.0053
Echinococcus multilocularis	neuropeptide receptor	0.0206	0.142	0.142
Brugia malayi	hypothetical protein	0.0206	0.142	0.8473
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0206	0.142	0.142
Schistosoma mansoni	bile acid beta-glucosidase-related	0.041	0.2955	0.2955
Echinococcus granulosus	G protein coupled receptor 139	0.0206	0.142	0.142
Onchocerca volvulus		0.0206	0.142	0.8436
Schistosoma mansoni	microtubule-associated protein tau	0.1349	1	1
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Trichomonas vaginalis	glucosylceramidase, putative	0.0155	0.1042	0.6256
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Leishmania major	target of rapamycin (TOR) kinase 2, putative	0.0045	0.0215	0.4484
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0206	0.142	0.142
Echinococcus multilocularis	ferritin	0.0017	0.0004	0.0004
Echinococcus multilocularis	neuropeptide receptor	0.0206	0.142	0.142
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Brugia malayi	hypothetical protein	0.0206	0.142	0.8473
Loa Loa (eye worm)	tubulin beta-1 chain	0.0023	0.0053	0.0271
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0206	0.142	0.142
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0206	0.142	0.142
Mycobacterium tuberculosis	Probable lipase LipD	0.0072	0.0415	0.1244
Trypanosoma brucei	Phosphatidylinositol 3-kinase tor1	0.0045	0.0215	0.4972
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0206	0.142	0.142
Brugia malayi	putative neuropeptide receptor NPR1	0.0206	0.142	0.8473
Echinococcus multilocularis	beta tubulin	0.0023	0.0053	0.0053
Echinococcus granulosus	7TM GPCR rhodopsin	0.0206	0.142	0.142
Onchocerca volvulus		0.0206	0.142	0.8436
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0027	0.0077	0.0444
Echinococcus granulosus	bile acid beta glucosidase	0.041	0.2955	0.2955
Schistosoma mansoni	hypothetical protein	0.0206	0.142	0.142
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0206	0.142	0.142
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0033	0.0129	0.0754
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0024	0.006	0.0339
Loa Loa (eye worm)	phosphatidylinositol 3	0.0045	0.0215	0.1102
Brugia malayi	Pre-SET motif family protein	0.003	0.0103	0.0612
Echinococcus multilocularis	tubulin, beta 4A class IVa	0.0023	0.0053	0.0053
Loa Loa (eye worm)	G-protein coupled receptor	0.0206	0.142	0.7262
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0206	0.142	0.142
Onchocerca volvulus		0.0206	0.142	0.8436
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Echinococcus granulosus	g protein coupled receptor	0.0206	0.142	0.142
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0206	0.142	0.142
Schistosoma mansoni	ferritin light chain	0.0017	0.0004	0.0004
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0206	0.142	0.8436
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0206	0.142	0.142
Mycobacterium ulcerans	long-chain fatty-acid CoA ligase	0.0047	0.0232	0.555
Schistosoma mansoni	ferritin	0.0017	0.0004	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Echinococcus multilocularis	bile acid beta glucosidase	0.041	0.2955	0.2955
Trichomonas vaginalis	glucosylceramidase, putative	0.0155	0.1042	0.6256
Loa Loa (eye worm)	hypothetical protein	0.0049	0.0244	0.1246
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0035	0.0142	0.3372
Giardia lamblia	GTOR	0.0045	0.0215	1
Mycobacterium tuberculosis	Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase)	0.0035	0.0142	0.0419
Schistosoma mansoni	tubulin subunit beta	0.0023	0.0053	0.0053
Trypanosoma brucei	phosphatidylinositol 4-kinase, putative	0.0045	0.0215	0.4972
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0206	0.142	0.142
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0206	0.142	0.142
Trichomonas vaginalis	glucosylceramidase, putative	0.0237	0.1653	0.9933
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0206	0.142	0.142
Loa Loa (eye worm)	hypothetical protein	0.0072	0.0415	0.2124
Echinococcus granulosus	histone lysine methyltransferase setb	0.003	0.0103	0.0103
Treponema pallidum	bacterioferrin (TpF1)	0.0017	0.0004	0.5
Echinococcus granulosus	rhodopsin orphan GPCR	0.0206	0.142	0.142
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0206	0.142	0.142
Schistosoma mansoni	neuropeptide F-like receptor	0.0206	0.142	0.142
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0232	0.1187
Trichomonas vaginalis	tubulin epsilon chain, putative	0.0023	0.0053	0.0297
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0206	0.142	0.8473
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0206	0.142	0.8473
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0024	0.006	0.0337
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Trichomonas vaginalis	tubulin epsilon chain, putative	0.0023	0.0053	0.0297
Echinococcus granulosus	tubulin subunit beta	0.0023	0.0053	0.0053
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0206	0.142	0.142
Schistosoma mansoni	adenoreceptor	0.0206	0.142	0.142
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0206	0.142	0.142
Loa Loa (eye worm)	beta-tubulin	0.0023	0.0053	0.0271
Trichomonas vaginalis	tubulin alpha chain, putative	0.0023	0.0053	0.0297
Schistosoma mansoni	neuropeptide receptor	0.0206	0.142	0.142
Echinococcus granulosus	neuropeptide s receptor	0.0206	0.142	0.142
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0206	0.142	0.142
Echinococcus granulosus	Tubulin beta 2C chain	0.0023	0.0053	0.0053
Mycobacterium tuberculosis	Probable hydrolase	0.0072	0.0415	0.1244
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.003	0.0103	0.0103
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0206	0.142	0.8473
Trichomonas vaginalis	glucosylceramidase, putative	0.0164	0.1105	0.6634
Echinococcus granulosus	beta tubulin	0.0023	0.0053	0.0053
Trypanosoma cruzi	Phosphatidylinositol 3-kinase tor2	0.0045	0.0215	0.4484
Schistosoma mansoni	hypothetical protein	0.0206	0.142	0.142
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0072	0.0415	0.0415
Echinococcus multilocularis	neuropeptides capa receptor	0.0206	0.142	0.142
Brugia malayi	AKH receptor	0.0206	0.142	0.8473
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0038	0.0166	0.0978
Echinococcus multilocularis	somatostatin receptor	0.0206	0.142	0.142
Echinococcus granulosus	tubulin beta 1 chain	0.0023	0.0053	0.0053
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0206	0.142	0.142
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Trichomonas vaginalis	glucosylceramidase, putative	0.0155	0.1042	0.6256
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0027	0.0079	0.0456
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.003	0.0103	0.1369
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0206	0.142	0.142
Schistosoma mansoni	cellular tumor antigen P53	0.0099	0.0617	0.0617
Schistosoma mansoni	neuropeptide F-like receptor	0.0206	0.142	0.142
Toxoplasma gondii	ABC1 family protein	0.0072	0.0415	1
Trichomonas vaginalis	tubulin beta chain, putative	0.0023	0.0053	0.0297
Echinococcus granulosus	Tubulin beta 2C chain	0.0023	0.0053	0.0053
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0033	0.0128	0.0376
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0047	0.0232	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0036	0.0146	0.0859
Brugia malayi	neuropeptide F receptor	0.0206	0.142	0.8473
Wolbachia endosymbiont of Brugia malayi	bacterioferritin/cytochrome b1	0.0017	0.0004	0.5
Trichomonas vaginalis	glucosylceramidase, putative	0.0237	0.1653	0.9933
Loa Loa (eye worm)	hypothetical protein	0.0072	0.0415	0.2124
Loa Loa (eye worm)	hypothetical protein	0.0099	0.0617	0.3157
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0049	0.0244	0.1454
Brugia malayi	beta-tubulin, identical	0.0023	0.0053	0.0317
Loa Loa (eye worm)	tubulin beta-2A chain	0.0023	0.0053	0.0271
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0047	0.0232	1
Schistosoma mansoni	ferritin light chain	0.0017	0.0004	0.0004
Echinococcus granulosus	orexin receptor type 2	0.0206	0.142	0.142
Trichomonas vaginalis	D-aminoacylase, putative	0.0072	0.0415	0.2479
Brugia malayi	AMP-binding enzyme family protein	0.0047	0.0232	0.1385
Echinococcus multilocularis	expressed protein	0.0017	0.0004	0.0004
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0206	0.142	0.8473
Mycobacterium ulcerans	acyl-CoA synthetase	0.0047	0.0232	0.555
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0142	0.0729
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Echinococcus granulosus	beta LACTamase domain containing family member	0.0072	0.0415	0.0415
Brugia malayi	O-Glycosyl hydrolase family 30 protein	0.0237	0.1653	0.9864
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0024	0.006	0.0337
Leishmania major	4-coumarate:coa ligase-like protein	0.0047	0.0232	0.4944
Schistosoma mansoni	family S12 unassigned peptidase (S12 family)	0.0072	0.0415	0.0415
Echinococcus granulosus	neuropeptides capa receptor	0.0206	0.142	0.142
Loa Loa (eye worm)	hypothetical protein	0.0072	0.0415	0.2124
Brugia malayi	G-protein coupled receptor	0.0206	0.142	0.8473
Echinococcus granulosus	rhodopsin orphan GPCR	0.0206	0.142	0.142
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0033	0.0128	0.0376
Echinococcus granulosus	g-protein coupled receptor	0.0206	0.142	0.142
Echinococcus multilocularis	Tubulin beta 2C chain	0.0023	0.0053	0.0053
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0206	0.142	0.142
Mycobacterium tuberculosis	Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase)	0.0047	0.0232	0.069
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0206	0.142	0.142
Mycobacterium ulcerans	long-chain-fatty-acid-CoA ligase	0.0047	0.0232	0.555
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0206	0.142	0.142
Echinococcus granulosus	neuropeptide FF receptor 2	0.0206	0.142	0.142
Brugia malayi	hypothetical protein	0.0206	0.142	0.8473
Plasmodium vivax	hypothetical protein, conserved	0.0072	0.0415	1
Schistosoma mansoni	hypothetical protein	0.0033	0.0128	0.0128
Mycobacterium ulcerans	esterase/lipase LipP	0.0072	0.0415	1
Schistosoma mansoni	biogenic amine receptor	0.0206	0.142	0.142
Leishmania major	4-coumarate:coa ligase-like protein	0.0047	0.0232	0.4944
Mycobacterium ulcerans	beta-lactamase	0.0072	0.0415	1
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Loa Loa (eye worm)	melatonin receptor type 1A	0.0206	0.142	0.7262
Onchocerca volvulus		0.0206	0.142	0.8436
Trichomonas vaginalis	tubulin, putative	0.0023	0.0053	0.0297
Echinococcus granulosus	fmrfamide receptor	0.0206	0.142	0.142
Trichomonas vaginalis	glucosylceramidase, putative	0.0155	0.1042	0.6256
Leishmania major	4-coumarate:coa ligase-like protein	0.0047	0.0232	0.4944
Schistosoma mansoni	apoferritin-2	0.0017	0.0004	0.0004
Mycobacterium tuberculosis	Conserved protein	0.0072	0.0415	0.1244
Echinococcus multilocularis	g protein coupled receptor	0.0206	0.142	0.142
Echinococcus multilocularis	neuropeptide receptor A26	0.0206	0.142	0.142
Schistosoma mansoni	tubulin subunit beta	0.0023	0.0053	0.0053
Brugia malayi	AMP-binding enzyme family protein	0.0047	0.0232	0.1385
Loa Loa (eye worm)	MH2 domain-containing protein	0.024	0.1676	0.8571
Echinococcus granulosus	FKBP12 rapamycin complex associated protein	0.0045	0.0215	0.0215
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0206	0.142	0.142
Onchocerca volvulus		0.0072	0.0415	0.2002
Echinococcus multilocularis	fmrfamide receptor	0.0206	0.142	0.142
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0206	0.142	0.142
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0045	0.0215	0.1275
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0206	0.142	0.142
Trichomonas vaginalis	glucosylceramidase, putative	0.0237	0.1653	0.9933
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0232	0.1187
Echinococcus multilocularis	Tubulin beta 2C chain	0.0023	0.0053	0.0053
Echinococcus multilocularis	g-protein coupled receptor	0.0206	0.142	0.142
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0033	0.0129	0.0754
Echinococcus granulosus	tm gpcr rhodopsin	0.0206	0.142	0.142
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0047	0.0232	0.069
Onchocerca volvulus		0.0206	0.142	0.8436
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Trichomonas vaginalis	glucosylceramidase, putative	0.0237	0.1653	0.9933
Brugia malayi	MH2 domain containing protein	0.024	0.1676	1
Brugia malayi	Tubulin beta-1 chain	0.0023	0.0053	0.0317
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Brugia malayi	sulfakinin receptor protein	0.0206	0.142	0.8473
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0033	0.0129	0.0754
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0029	0.0094	0.0094
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0206	0.142	0.142
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.003	0.0103	0.0103
Schistosoma mansoni	neuropeptide receptor	0.0206	0.142	0.142
Echinococcus granulosus	sex peptide receptor	0.0206	0.142	0.142
Echinococcus granulosus	neuropeptide receptor	0.0206	0.142	0.142
Echinococcus granulosus	tumor protein p63	0.0673	0.4932	0.4932
Echinococcus granulosus	g protein coupled receptor	0.0206	0.142	0.142
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0206	0.142	0.142
Trichomonas vaginalis	D-aminoacylase, putative	0.0072	0.0415	0.2479
Schistosoma mansoni	opsin-like receptor	0.0206	0.142	0.142
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.003	0.0103	0.0103
Onchocerca volvulus		0.0206	0.142	0.8436
Entamoeba histolytica	acyl-coA synthetase, putative	0.0047	0.0232	1
Loa Loa (eye worm)	G-protein coupled receptor	0.0206	0.142	0.7262
Trichomonas vaginalis	penicillin-binding protein, putative	0.0072	0.0415	0.2479
Echinococcus granulosus	rhodopsin orphan GPCR	0.0206	0.142	0.142
Loa Loa (eye worm)	neuropeptide F receptor	0.0206	0.142	0.7262
Mycobacterium tuberculosis	Possible penicillin-binding protein	0.0458	0.3313	1
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0206	0.142	0.7262
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0206	0.142	0.142
Schistosoma mansoni	ferritin	0.0017	0.0004	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0049	0.0244	0.1246
Echinococcus multilocularis	neuropeptide s receptor	0.0206	0.142	0.142
Schistosoma mansoni	ferritin	0.0017	0.0004	0.0004
Trichomonas vaginalis	tubulin gamma chain, putative	0.0023	0.0053	0.0297
Brugia malayi	G protein-coupled receptor F59B2.13	0.0206	0.142	0.8473
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0206	0.142	0.7262
Echinococcus granulosus	neuropeptide receptor A26	0.0206	0.142	0.142
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0206	0.142	0.142
Trichomonas vaginalis	PIKK family atypical protein kinase	0.003	0.0104	0.0605
Mycobacterium ulcerans	fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE	0.0072	0.0415	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0033	0.0129	0.0754
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0206	0.142	0.142
Schistosoma mansoni	tubulin subunit beta	0.0023	0.0053	0.0053
Brugia malayi	Dopamine receptor protein 1	0.0206	0.142	0.8473
Trypanosoma brucei	beta tubulin	0.0023	0.0053	0.0886
Loa Loa (eye worm)	neuropeptide F receptor	0.0206	0.142	0.7262
Echinococcus multilocularis	g protein coupled receptor	0.0206	0.142	0.142
Echinococcus multilocularis	fmrfamide receptor	0.0206	0.142	0.142
Brugia malayi	hypothetical protein	0.0206	0.142	0.8473
Trypanosoma brucei	phosphatidylinositol 3-kinase tor, putative	0.0021	0.0037	0.049
Brugia malayi	follicle stimulating hormone receptor	0.0206	0.142	0.8473
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0033	0.0128	0.0376
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.003	0.0103	0.0103
Trypanosoma cruzi	hypothetical protein, conserved	0.0072	0.0415	1
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0206	0.142	0.7262
Schistosoma mansoni	hypothetical protein	0.0206	0.142	0.142
Onchocerca volvulus		0.0206	0.142	0.8436
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0206	0.142	0.142
Onchocerca volvulus		0.0206	0.142	0.8436
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0206	0.142	0.142
Echinococcus multilocularis	tumor protein p63	0.0673	0.4932	0.4932
Loa Loa (eye worm)	O-glycosyl hydrolase family 30 protein	0.0237	0.1653	0.8454
Mycobacterium ulcerans	lipase LipD	0.0072	0.0415	1
Loa Loa (eye worm)	beta-LACTamase domain containing family member	0.0072	0.0415	0.2124
Onchocerca volvulus		0.0206	0.142	0.8436
Echinococcus granulosus	tm gpcr rhodopsin	0.0206	0.142	0.142
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0206	0.142	0.8436
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Mycobacterium leprae	conserved hypothetical protein	0.0072	0.0415	1
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Trichomonas vaginalis	glucosylceramidase, putative	0.0155	0.1042	0.6256
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0024	0.006	0.0339
Chlamydia trachomatis	acylglycerophosphoethanolamine acyltransferase	0.0035	0.0142	0.5
Loa Loa (eye worm)	transcription factor SMAD2	0.024	0.1676	0.8571
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0206	0.142	0.142
Brugia malayi	hypothetical protein	0.0206	0.142	0.8473
Mycobacterium tuberculosis	Probable lipase LipE	0.0072	0.0415	0.1244
Schistosoma mansoni	bile acid beta-glucosidase-related	0.041	0.2955	0.2955
Brugia malayi	AMP-binding enzyme family protein	0.0047	0.0232	0.1385
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Echinococcus multilocularis	g protein coupled receptor	0.0206	0.142	0.142
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Echinococcus multilocularis	Tubulin beta 2C chain	0.0023	0.0053	0.0053
Schistosoma mansoni	apoferritin-2	0.0017	0.0004	0.0004
Echinococcus multilocularis	non lysosomal glucosylceramidase	0.041	0.2955	0.2955
Schistosoma mansoni	histamine h1 receptor	0.0206	0.142	0.142
Mycobacterium ulcerans	hypothetical protein	0.0047	0.0232	0.555
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Onchocerca volvulus		0.0072	0.0415	0.2002
Brugia malayi	putative neuropeptide receptor	0.0206	0.142	0.8473
Echinococcus granulosus	rhodopsin orphan GPCR	0.0206	0.142	0.142
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Brugia malayi	G protein-coupled receptor	0.0206	0.142	0.8473
Onchocerca volvulus		0.0206	0.142	0.8436
Trichomonas vaginalis	glucosylceramidase, putative	0.0164	0.1105	0.6634
Echinococcus granulosus	neuropeptide receptor	0.0206	0.142	0.142
Echinococcus granulosus	biogenic amine 5HT receptor	0.0206	0.142	0.142
Plasmodium vivax	SET domain protein, putative	0.003	0.0103	0.1369
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Trypanosoma brucei	hypothetical protein, conserved	0.0072	0.0415	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0206	0.142	0.142
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Loa Loa (eye worm)	hypothetical protein	0.0072	0.0415	0.2124
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0033	0.0129	0.0754
Mycobacterium tuberculosis	Probable esterase LipL	0.0072	0.0415	0.1244
Onchocerca volvulus		0.0206	0.142	0.8436
Trichomonas vaginalis	D-aminoacylase, putative	0.0072	0.0415	0.2479
Trypanosoma brucei	target of rapamycin kinase 3, putative	0.0036	0.0147	0.3239
Mycobacterium tuberculosis	Conserved protein	0.0072	0.0415	0.1244
Loa Loa (eye worm)	tubulin beta chain	0.0023	0.0053	0.0271
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0206	0.142	0.142
Echinococcus multilocularis	FKBP12 rapamycin complex associated protein	0.0045	0.0215	0.0215
Echinococcus granulosus	Tubulin beta 2C chain	0.0023	0.0053	0.0053
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0142	0.0729
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0206	0.142	0.142
Echinococcus multilocularis	neuropeptide Y receptor	0.0206	0.142	0.142
Onchocerca volvulus		0.0047	0.0232	0.0829
Echinococcus multilocularis	beta LACTamase domain containing family member	0.0072	0.0415	0.0415
Echinococcus granulosus	expressed protein	0.0017	0.0004	0.0004
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0036	0.0146	0.0859
Echinococcus granulosus	neuropeptides capa receptor	0.0206	0.142	0.142
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0045	0.0215	0.1275
Trichomonas vaginalis	set domain proteins, putative	0.0238	0.1664	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0206	0.142	0.142
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0232	0.1187
Mycobacterium leprae	Probable lipase LipE	0.0072	0.0415	1
Schistosoma mansoni	ataxia telangiectasia mutated (atm)-related	0.0045	0.0215	0.0215
Echinococcus multilocularis	tubulin beta 1 chain	0.0023	0.0053	0.0053
Brugia malayi	RE15519p	0.0206	0.142	0.8473
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Leishmania major	target of rapamycin kinase (TOR) kinase 3	0.0036	0.0147	0.2582
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0206	0.142	0.142
Mycobacterium tuberculosis	Conserved protein	0.0072	0.0415	0.1244
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0036	0.0146	0.0859
Brugia malayi	G-protein coupled receptor	0.0206	0.142	0.8473
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0206	0.142	0.142
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0047	0.0232	0.555
Plasmodium vivax	acyl-CoA synthetase, putative	0.0035	0.0142	0.2468
Brugia malayi	Dopamine receptor	0.0206	0.142	0.8473
Echinococcus granulosus	non lysosomal glucosylceramidase	0.041	0.2955	0.2955
Schistosoma mansoni	amine GPCR	0.0206	0.142	0.142
Echinococcus multilocularis	Tubulin beta 2C chain	0.0023	0.0053	0.0053
Mycobacterium ulcerans	acyl-CoA synthetase	0.0047	0.0232	0.555
Schistosoma mansoni	tubulin subunit beta	0.0023	0.0053	0.0053
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0206	0.142	0.142
Echinococcus granulosus	biogenic amine 5HT receptor	0.0206	0.142	0.142
Schistosoma mansoni	amine GPCR	0.0206	0.142	0.142
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0027	0.0079	0.0456
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0036	0.0146	0.0859
Mycobacterium ulcerans	acyl-CoA synthetase	0.0047	0.0232	0.555
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0033	0.0128	0.0376
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0206	0.142	0.7262
Echinococcus granulosus	tm gpcr rhodopsin	0.0206	0.142	0.142
Echinococcus multilocularis	serotonin receptor	0.0206	0.142	0.142
Onchocerca volvulus		0.0206	0.142	0.8436
Schistosoma mansoni	myosin xvIII	0.0206	0.142	0.142
Echinococcus granulosus	allatostatin A receptor	0.0206	0.142	0.142
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0047	0.0232	0.555
Trichomonas vaginalis	glucosylceramidase, putative	0.0237	0.1653	0.9933
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0206	0.142	0.142
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0142	0.0729
Brugia malayi	Pre-SET motif family protein	0.0209	0.1447	0.8636
Echinococcus granulosus	dro:myosuppressin receptor	0.0206	0.142	0.142
Brugia malayi	hypothetical protein	0.0206	0.142	0.8473
Schistosoma mansoni	hypothetical protein	0.0206	0.142	0.142
Brugia malayi	Serotonin receptor	0.0206	0.142	0.8473
Onchocerca volvulus	Glucosylceramidase homolog	0.0155	0.1042	0.6019
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Trichomonas vaginalis	penicillin-binding protein, putative	0.0072	0.0415	0.2479
Entamoeba histolytica	phosphatidylinositol3-kinaseTor2, putative	0.0045	0.0215	0.907
Brugia malayi	beta-lactamase family protein	0.0072	0.0415	0.2478
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0206	0.142	0.142
Echinococcus multilocularis	orexin receptor type 2	0.0206	0.142	0.142
Brugia malayi	larval opioid receptor	0.0206	0.142	0.8473
Schistosoma mansoni	neuropeptide receptor	0.0206	0.142	0.142
Mycobacterium tuberculosis	Possible conserved lipoprotein LpqK	0.0072	0.0415	0.1244
Echinococcus granulosus	rhodopsin orphan GPCR	0.0206	0.142	0.142
Loa Loa (eye worm)	hypothetical protein	0.0072	0.0415	0.2124
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0206	0.142	0.142
Echinococcus granulosus	hypothetical protein	0.0206	0.142	0.142
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0024	0.006	0.0339
Echinococcus granulosus	tubulin beta 4A class IVa	0.0023	0.0053	0.0053
Plasmodium falciparum	acyl-CoA synthetase	0.0035	0.0142	1
Brugia malayi	Serotonin receptor	0.0206	0.142	0.8473
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0206	0.142	0.142
Echinococcus granulosus	rhodopsin orphan GPCR	0.0206	0.142	0.142
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0206	0.142	0.142
Entamoeba histolytica	FKBP-rapamycin associated protein (FRAP), putative	0.0045	0.0215	0.907
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0033	0.0129	0.0754
Schistosoma mansoni	amine GPCR	0.0206	0.142	0.142
Trichomonas vaginalis	esterase, putative	0.0072	0.0415	0.2479
Echinococcus granulosus	serotonin receptor	0.0206	0.142	0.142
Onchocerca volvulus		0.0206	0.142	0.8436
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0206	0.142	0.142
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0206	0.142	0.7262
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0206	0.142	0.142
Loa Loa (eye worm)	hypothetical protein	0.0072	0.0415	0.2124
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0036	0.0146	0.0859
Brugia malayi	beta-lactamase family protein	0.0072	0.0415	0.2478
Echinococcus multilocularis	allatostatin A receptor	0.0206	0.142	0.142
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0029	0.0097	0.0561
Leishmania major	target of rapamycin (TOR) kinase 1, putative	0.0045	0.0215	0.4484
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0045	0.0215	0.1286
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0206	0.142	0.142
Echinococcus multilocularis	dro:myosuppressin receptor	0.0206	0.142	0.142
Brugia malayi	Dopamine receptor protein 2	0.0206	0.142	0.8473
Trypanosoma brucei	beta tubulin	0.0023	0.0053	0.0886
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0142	0.0729
Echinococcus granulosus	beta tubulin	0.0023	0.0053	0.0053
Brugia malayi	Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative	0.0072	0.0415	0.2478
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0033	0.0129	0.0754
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0045	0.0215	0.1275
Onchocerca volvulus		0.0072	0.0415	0.2002
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0206	0.142	0.142
Schistosoma mansoni	amine GPCR	0.0206	0.142	0.142
Brugia malayi	hypothetical protein	0.0206	0.142	0.8473
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Onchocerca volvulus		0.0238	0.1664	1
Loa Loa (eye worm)	hypothetical protein	0.003	0.0103	0.0525
Schistosoma mansoni	tubulin subunit beta	0.0023	0.0053	0.0053
Schistosoma mansoni	biogenic amine receptor	0.0206	0.142	0.142
Schistosoma mansoni	growth hormone secretagogue receptor	0.0206	0.142	0.142
Onchocerca volvulus		0.0206	0.142	0.8436
Trichomonas vaginalis	glucosylceramidase, putative	0.0155	0.1042	0.6256
Schistosoma mansoni	opsin-like receptor	0.0206	0.142	0.142
Echinococcus multilocularis	G protein coupled receptor 139	0.0206	0.142	0.142
Loa Loa (eye worm)	tubulin beta-4 chain	0.0023	0.0053	0.0271
Brugia malayi	ORL1-like opioid receptor	0.0206	0.142	0.8473
Loa Loa (eye worm)	beta-lactamase	0.0072	0.0415	0.2124
Brugia malayi	neuropeptide F receptor	0.0206	0.142	0.8473
Trichomonas vaginalis	glucosylceramidase, putative	0.0237	0.1653	0.9933
Brugia malayi	latrophilin 2 splice variant baaae	0.0033	0.0128	0.0763
Schistosoma mansoni	ferritin	0.0017	0.0004	0.0004
Echinococcus multilocularis	microtubule associated protein 2	0.1349	1	1
Echinococcus multilocularis	tubulin subunit beta	0.0023	0.0053	0.0053
Onchocerca volvulus		0.0206	0.142	0.8436
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0206	0.142	0.142
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0206	0.142	0.8473
Trypanosoma brucei	beta tubulin	0.0023	0.0053	0.0886
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0024	0.006	0.0339
Trypanosoma cruzi	Phosphatidylinositol 3-kinase tor1	0.0045	0.0215	0.4484
Brugia malayi	hypothetical protein	0.0206	0.142	0.8473
Echinococcus multilocularis	serotonin receptor	0.0206	0.142	0.142
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0047	0.0232	0.555
Brugia malayi	hypothetical protein	0.0206	0.142	0.8473
Trypanosoma cruzi	target of rapamycin kinase 3	0.0036	0.0147	0.2582
Echinococcus granulosus	g protein coupled receptor	0.0206	0.142	0.142
Echinococcus granulosus	ferritin	0.0017	0.0004	0.0004
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0206	0.142	0.142
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0206	0.142	0.142
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0027	0.0079	0.0456
Onchocerca volvulus		0.0206	0.142	0.8436
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0027	0.0077	0.0444
Brugia malayi	hypothetical protein	0.0206	0.142	0.8473
Echinococcus granulosus	neuropeptide Y receptor	0.0206	0.142	0.142
Loa Loa (eye worm)	BEN-1 protein	0.0023	0.0053	0.0271
Loa Loa (eye worm)	hypothetical protein	0.0277	0.1955	1
Schistosoma mansoni	opsin-like receptor	0.0206	0.142	0.142
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Brugia malayi	Melatonin receptor type 1A	0.0206	0.142	0.8473
Echinococcus granulosus	Tubulin beta 2C chain	0.0023	0.0053	0.0053
Echinococcus granulosus	neuropeptide Y receptor	0.0206	0.142	0.142
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0206	0.142	0.8473
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0206	0.142	0.142
Leishmania major	hypothetical protein, conserved	0.0072	0.0415	1
Mycobacterium tuberculosis	Probable esterase/lipase LipP	0.0072	0.0415	0.1244
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0206	0.142	0.142
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0024	0.006	0.0337
Schistosoma mansoni	tubulin subunit beta	0.0023	0.0053	0.0053
Trichomonas vaginalis	glucosylceramidase, putative	0.0155	0.1042	0.6256
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0206	0.142	0.142
Mycobacterium tuberculosis	Probable conserved lipoprotein	0.0072	0.0415	0.1244
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0128	0.0654
Mycobacterium ulcerans	long-chain-fatty-acid--CoA ligase	0.0047	0.0232	0.555
Echinococcus multilocularis	neuropeptide Y receptor	0.0206	0.142	0.142
Schistosoma mansoni	amine GPCR	0.0206	0.142	0.142
Trypanosoma cruzi	hypothetical protein, conserved	0.0072	0.0415	1
Echinococcus multilocularis	sex peptide receptor	0.0206	0.142	0.142
Echinococcus multilocularis	neuropeptides capa receptor	0.0206	0.142	0.142
Schistosoma mansoni	neuropeptide receptor	0.0206	0.142	0.142
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0209	0.1447	0.7402
Echinococcus granulosus	somatostatin receptor	0.0206	0.142	0.142
Echinococcus granulosus	Tubulin beta 2C chain	0.0023	0.0053	0.0053
Onchocerca volvulus		0.0099	0.0617	0.3296
Schistosoma mansoni	neuropeptide f receptor 76f	0.0206	0.142	0.142
Brugia malayi	beta-lactamase	0.0072	0.0415	0.2478
Trypanosoma brucei	beta tubulin	0.0023	0.0053	0.0886
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0049	0.0244	0.1454
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0206	0.142	0.142
Onchocerca volvulus		0.0206	0.142	0.8436
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.003	0.0103	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0206	0.142	0.142
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0206	0.142	0.142
Loa Loa (eye worm)	BEN-1 protein	0.0023	0.0053	0.0271
Loa Loa (eye worm)	TYRA-2 protein	0.0206	0.142	0.7262
Mycobacterium ulcerans	hypothetical protein	0.0072	0.0415	1
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.003	0.0103	0.0103
Echinococcus granulosus	7tm_1 domain containing protein	0.0206	0.142	0.142
Echinococcus granulosus	rhodopsin orphan GPCR	0.0206	0.142	0.142
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0142	0.0729
Schistosoma mansoni	biogenic amine receptor	0.0206	0.142	0.142
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Loa Loa (eye worm)	hypothetical protein	0.0206	0.142	0.7262
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0206	0.142	0.142

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Search by Saint Jude

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 806763