TDR Targets

Basic information

Technical information

TDR Targets ID: 808123
Name: (dibutylphosphorylmethyl-phenylphosphoryl)ben zene
MW: 376.409 | Formula: C21H30O2P2
H donors: 0 H acceptors: 2 LogP: 4.25 Rotable bonds: 10
Rule of 5 violations (Lipinski): 1
SMILES: CCCCP(=O)(CP(=O)(c1ccccc1)c1ccccc1)CCCC
InChi: 1S/C21H30O2P2/c1-3-5-17-24(22,18-6-4-2)19-25(23,20-13-9-7-10-14-20)21-15-11-8-12-16-21/h7-16H,3-6,17-19H2,1-2H3
InChiKey: QNHIGNLRUSRXHO-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

(dibutylphosphorylmethyl-phenyl-phosphoryl)benzene
CBMicro_012412
BIM-0012246.P001

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Brugia malayi	Egg laying defective protein 4	0.0086	0.0281	0.0028
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0295	0.2613	0.2421
Echinococcus granulosus	hypothetical protein	0.0295	0.2613	0.2421
Loa Loa (eye worm)	voltage and ligand gated potassium channel	0.0629	0.6322	0.6226
Mycobacterium ulcerans	regulatory protein	0.0083	0.0254	0.5
Echinococcus multilocularis	neuropeptide receptor	0.0295	0.2613	0.2421
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0295	0.2613	0.2421
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0295	0.2613	0.2421
Echinococcus granulosus	neuropeptide receptor A26	0.0295	0.2613	0.2421
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0124	0.0714	0.0472
Echinococcus multilocularis	neuropeptide Y receptor	0.0295	0.2613	0.2421
Echinococcus granulosus	biogenic amine 5HT receptor	0.0295	0.2613	0.2421
Onchocerca volvulus		0.0295	0.2613	1
Echinococcus multilocularis	serotonin transporter	0.0093	0.0363	0.0112
Loa Loa (eye worm)	hypothetical protein	0.0093	0.0363	0.0112
Onchocerca volvulus		0.0295	0.2613	1
Schistosoma mansoni	biogenic amine receptor	0.0295	0.2613	0.2421
Echinococcus granulosus	g protein coupled receptor	0.0295	0.2613	0.2421
Onchocerca volvulus		0.0295	0.2613	1
Echinococcus granulosus	hyperpolarization activated cyclic	0.0124	0.0714	0.0472
Loa Loa (eye worm)	AGC/PKG protein kinase	0.0086	0.0281	0.0028
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Schistosoma mansoni	hypothetical protein	0.0295	0.2613	0.2421
Loa Loa (eye worm)	norepinephrine transporter	0.0093	0.0363	0.0112
Echinococcus granulosus	rhodopsin orphan GPCR	0.0295	0.2613	0.2421
Echinococcus granulosus	neuropeptide receptor	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0083	0.0254	0.5
Leishmania major	protein kinase, putative	0.0086	0.0281	1
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0295	0.2613	0.2421
Leishmania major	protein kinase, putative	0.0086	0.0281	1
Plasmodium falciparum	cGMP-dependent protein kinase	0.0086	0.0281	1
Onchocerca volvulus		0.0295	0.2613	1
Echinococcus granulosus	7TM GPCR rhodopsin	0.0295	0.2613	0.2421
Schistosoma mansoni	biogenic amine receptor	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0295	0.2613	0.2421
Loa Loa (eye worm)	cyclic-nucleotide gated cation channel	0.0124	0.0714	0.0472
Schistosoma mansoni	sodium/chloride dependent transporter	0.0093	0.0363	0.0112
Echinococcus granulosus	orexin receptor type 2	0.0295	0.2613	0.2421
Echinococcus multilocularis	neuropeptides capa receptor	0.0295	0.2613	0.2421
Brugia malayi	G protein-coupled receptor	0.0295	0.2613	0.2421
Trypanosoma brucei	Flagellar Member 6	0.0083	0.0254	1
Brugia malayi	hypothetical protein	0.0295	0.2613	0.2421
Echinococcus granulosus	neuropeptides capa receptor	0.0295	0.2613	0.2421
Echinococcus multilocularis	MAP kinase activated protein kinase 2	0.096	1	1
Brugia malayi	Sodium:neurotransmitter symporter family protein	0.0093	0.0363	0.0112
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Brugia malayi	G protein-coupled receptor F59B2.13	0.0295	0.2613	0.2421
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0295	0.2613	0.2421
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0124	0.0714	0.0472
Echinococcus multilocularis	somatostatin receptor	0.0295	0.2613	0.2421
Echinococcus granulosus	neuropeptide receptor	0.0295	0.2613	0.2421
Echinococcus multilocularis	serotonin receptor	0.0295	0.2613	0.2421
Mycobacterium tuberculosis	Probable conserved transmembrane transport protein	0.0083	0.0254	0.5
Brugia malayi	Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog	0.0629	0.6322	0.6226
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Echinococcus granulosus	serotonin receptor	0.0295	0.2613	0.2421
Echinococcus multilocularis	voltage gated potassium channel	0.0182	0.1356	0.1131
Echinococcus granulosus	rhodopsin orphan GPCR	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Echinococcus multilocularis	sex peptide receptor	0.0295	0.2613	0.2421
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0295	0.2613	0.2421
Onchocerca volvulus		0.0295	0.2613	1
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0295	0.2613	0.2421
Schistosoma mansoni	60S ribosomal protein L21	0.0099	0.0433	0.0184
Trypanosoma cruzi	regulatory subunit of protein kinase a-like protein, putative	0.0083	0.0254	0.5
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Brugia malayi	Serotonin receptor	0.0295	0.2613	0.2421
Echinococcus granulosus	tm gpcr rhodopsin	0.0295	0.2613	0.2421
Schistosoma mansoni	neuropeptide F-like receptor	0.0295	0.2613	0.2421
Echinococcus multilocularis	hyperpolarization activated cyclic	0.0124	0.0714	0.0472
Echinococcus granulosus	rhodopsin orphan GPCR	0.0295	0.2613	0.2421
Schistosoma mansoni	serine/threonine protein kinase	0.0086	0.0281	0.0028
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Brugia malayi	Dopamine receptor	0.0295	0.2613	0.2421
Trypanosoma brucei	cAMP response protein 1, putative	0.0083	0.0254	1
Schistosoma mansoni	biogenic amine receptor	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Toxoplasma gondii	protein kinase G AGC kinase family member PKG	0.0086	0.0281	1
Brugia malayi	hypothetical protein	0.0295	0.2613	0.2421
Echinococcus multilocularis	neuropeptide receptor	0.0295	0.2613	0.2421
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0295	0.2613	0.2421
Trypanosoma cruzi	cAMP response protein 1, putative	0.0083	0.0254	0.5
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0295	0.2613	0.2421
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0295	0.2613	0.2421
Echinococcus multilocularis	fmrfamide receptor	0.0295	0.2613	0.2421
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0295	0.2613	0.2421
Schistosoma mansoni	voltage-gated potassium channel	0.0182	0.1356	0.1131
Schistosoma mansoni	voltage-gated potassium channel	0.0687	0.6964	0.6885
Mycobacterium ulcerans	hypothetical protein	0.0083	0.0254	0.5
Mycobacterium ulcerans	hypothetical protein	0.0083	0.0254	0.5
Schistosoma mansoni	growth hormone secretagogue receptor	0.0295	0.2613	0.2421
Echinococcus granulosus	G protein coupled receptor 139	0.0295	0.2613	0.2421
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0295	0.2613	0.2421
Schistosoma mansoni	neuropeptide receptor	0.0295	0.2613	0.2421
Brugia malayi	RE15519p	0.0295	0.2613	0.2421
Brugia malayi	Dopamine receptor protein 1	0.0295	0.2613	0.2421
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0182	0.1356	0.1131
Mycobacterium tuberculosis	Probable glutamine-transport ATP-binding protein ABC transporter GlnQ	0.0083	0.0254	0.5
Trypanosoma cruzi	cAMP response protein 1	0.0083	0.0254	0.5
Loa Loa (eye worm)	melatonin receptor type 1A	0.0295	0.2613	0.2421
Brugia malayi	G-protein coupled receptor	0.0295	0.2613	0.2421
Echinococcus multilocularis	cGMP dependent protein kinase 1	0.0086	0.0281	0.0028
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Brugia malayi	hypothetical protein	0.0295	0.2613	0.2421
Brugia malayi	hypothetical protein	0.0295	0.2613	0.2421
Echinococcus granulosus	voltage gated potassium channel	0.0182	0.1356	0.1131
Loa Loa (eye worm)	cyclic-nucleotide gated cation channel	0.0124	0.0714	0.0472
Schistosoma mansoni	opsin-like receptor	0.0295	0.2613	0.2421
Echinococcus granulosus	rhodopsin orphan GPCR	0.0295	0.2613	0.2421
Echinococcus multilocularis	cyclic nucleotide gated cation channel	0.0124	0.0714	0.0472
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Brugia malayi	hypothetical protein	0.0295	0.2613	0.2421
Echinococcus granulosus	MAP kinase activated protein kinase 2	0.096	1	1
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Echinococcus granulosus	rhodopsin orphan GPCR	0.0295	0.2613	0.2421
Onchocerca volvulus		0.0295	0.2613	1
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0295	0.2613	0.2421
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0295	0.2613	0.2421
Brugia malayi	GnHR receptor homolog	0.0295	0.2613	0.2421
Schistosoma mansoni	amine GPCR	0.0295	0.2613	0.2421
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Echinococcus multilocularis	cyclic nucleotide gated cation channel alpha 3	0.0124	0.0714	0.0472
Onchocerca volvulus		0.0295	0.2613	1
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0295	0.2613	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0295	0.2613	0.2421
Trypanosoma cruzi	cyclic nucleotide-binding domain containing protein, putative	0.0083	0.0254	0.5
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Echinococcus granulosus	neuropeptides capa receptor	0.0295	0.2613	0.2421
Brugia malayi	G-protein coupled receptor	0.0295	0.2613	0.2421
Echinococcus multilocularis	serotonin receptor	0.0295	0.2613	0.2421
Echinococcus granulosus	tm gpcr rhodopsin	0.0295	0.2613	0.2421
Echinococcus granulosus	7tm_1 domain containing protein	0.0295	0.2613	0.2421
Treponema pallidum	sodium- and chloride- dependent transporter	0.0093	0.0363	1
Schistosoma mansoni	voltage-gated potassium channel	0.0124	0.0714	0.0472
Echinococcus multilocularis	dro:myosuppressin receptor	0.0295	0.2613	0.2421
Echinococcus granulosus	cyclic nucleotide gated cation channel alpha 3	0.0124	0.0714	0.0472
Schistosoma mansoni	voltage-gated potassium channel	0.0182	0.1356	0.1131
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0295	0.2613	0.2421
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Echinococcus granulosus	rhodopsin orphan GPCR	0.0295	0.2613	0.2421
Brugia malayi	putative neuropeptide receptor	0.0295	0.2613	0.2421
Echinococcus multilocularis	neuropeptide s receptor	0.0295	0.2613	0.2421
Schistosoma mansoni	histamine h1 receptor	0.0295	0.2613	0.2421
Onchocerca volvulus		0.0093	0.0363	0.0461
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0295	0.2613	0.2421
Trypanosoma cruzi	Flagellar Member 6	0.0083	0.0254	0.5
Brugia malayi	follicle stimulating hormone receptor	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0093	0.0363	0.0112
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Echinococcus multilocularis	fmrfamide receptor	0.0295	0.2613	0.2421
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0295	0.2613	0.2421
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0295	0.2613	0.2421
Brugia malayi	neuropeptide F receptor	0.0295	0.2613	0.2421
Echinococcus granulosus	neuropeptide FF receptor 2	0.0295	0.2613	0.2421
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0295	0.2613	0.2421
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0295	0.2613	0.2421
Brugia malayi	hypothetical protein	0.0295	0.2613	0.2421
Echinococcus multilocularis	orexin receptor type 2	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Brugia malayi	Dopamine receptor protein 2	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0295	0.2613	0.2421
Loa Loa (eye worm)	TYRA-2 protein	0.0295	0.2613	0.2421
Loa Loa (eye worm)	serotonin transporter b	0.0093	0.0363	0.0112
Brugia malayi	hypothetical protein	0.0295	0.2613	0.2421
Trypanosoma brucei	cyclic nucleotide-binding domain containing protein, putative	0.0083	0.0254	1
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0588	0.5862	1
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0295	0.2613	0.2421
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0295	0.2613	0.2421
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0295	0.2613	0.2421
Echinococcus granulosus	cGMP dependent protein kinase	0.0086	0.0281	0.0028
Echinococcus multilocularis	hyperpolarization activated cyclic	0.0124	0.0714	0.0472
Echinococcus granulosus	fmrfamide receptor	0.0295	0.2613	0.2421
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0295	0.2613	0.2421
Trypanosoma cruzi	regulatory subunit of protein kinase a-like protein, putative	0.0083	0.0254	0.5
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0295	0.2613	0.2421
Echinococcus granulosus	cGMP dependent protein kinase 1	0.0086	0.0281	0.0028
Schistosoma mansoni	amine GPCR	0.0295	0.2613	0.2421
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0295	0.2613	0.2421
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0295	0.2613	0.2421
Echinococcus multilocularis	g protein coupled receptor	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Schistosoma mansoni	myosin xvIII	0.0295	0.2613	0.2421
Echinococcus granulosus	rhodopsin orphan GPCR	0.0295	0.2613	0.2421
Giardia lamblia	CAMP-dependent protein kinase regulatory chain	0.0083	0.0254	0.5
Echinococcus granulosus	somatostatin receptor	0.0295	0.2613	0.2421
Schistosoma mansoni	neuropeptide f receptor 76f	0.0295	0.2613	0.2421
Echinococcus multilocularis	neuropeptides capa receptor	0.0295	0.2613	0.2421
Schistosoma mansoni	hyperpolarization activated cyclic nucleotide-gated potassium channel	0.0124	0.0714	0.0472
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0629	0.6322	0.6226
Trypanosoma cruzi	cAMP binding protein, putative	0.0083	0.0254	0.5
Onchocerca volvulus		0.0295	0.2613	1
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Schistosoma mansoni	cyclic-nucleotide-gated cation channel	0.0124	0.0714	0.0472
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0295	0.2613	0.2421
Onchocerca volvulus		0.0295	0.2613	1
Brugia malayi	Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog	0.0182	0.1356	0.1131
Brugia malayi	putative neuropeptide receptor NPR1	0.0295	0.2613	0.2421
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.0629	0.6322	0.6226
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0182	0.1356	0.1131
Brugia malayi	Cyclic-nucleotide gated cation channel	0.0124	0.0714	0.0472
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0295	0.2613	0.2421
Schistosoma mansoni	serine/threonine protein kinase	0.096	1	1
Schistosoma mansoni	neuropeptide receptor	0.0295	0.2613	0.2421
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0295	0.2613	0.2421
Echinococcus granulosus	g protein coupled receptor	0.0295	0.2613	0.2421
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0295	0.2613	0.2421
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0295	0.2613	0.2421
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0295	0.2613	0.2421
Echinococcus granulosus	tm gpcr rhodopsin	0.0295	0.2613	0.2421
Brugia malayi	Serotonin receptor	0.0295	0.2613	0.2421
Loa Loa (eye worm)	G-protein coupled receptor	0.0295	0.2613	0.2421
Brugia malayi	sulfakinin receptor protein	0.0295	0.2613	0.2421
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0124	0.0714	0.082
Echinococcus granulosus	neuropeptide s receptor	0.0295	0.2613	0.2421
Echinococcus granulosus	sex peptide receptor	0.0295	0.2613	0.2421
Echinococcus granulosus	hyperpolarization activated cyclic	0.0124	0.0714	0.0472
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0588	0.5862	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0295	0.2613	0.2421
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0295	0.2613	0.2421
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.0124	0.0714	0.082
Mycobacterium tuberculosis	Probable transcriptional regulatory protein Cmr	0.0083	0.0254	0.5
Onchocerca volvulus		0.0295	0.2613	1
Schistosoma mansoni	hyperpolarization activated cyclic nucleotide-gated potassium channel	0.0124	0.0714	0.0472
Loa Loa (eye worm)	neuropeptide F receptor	0.0295	0.2613	0.2421
Schistosoma mansoni	amine GPCR	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Schistosoma mansoni	norepinephrine/norepinephrine transporter	0.0093	0.0363	0.0112
Loa Loa (eye worm)	hypothetical protein	0.0124	0.0714	0.0472
Trypanosoma cruzi	hypothetical protein, conserved	0.0083	0.0254	0.5
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0295	0.2613	0.2421
Brugia malayi	hypothetical protein	0.0295	0.2613	0.2421
Schistosoma mansoni	neuropeptide receptor	0.0295	0.2613	0.2421
Schistosoma mansoni	hypothetical protein	0.0295	0.2613	0.2421
Brugia malayi	Melatonin receptor type 1A	0.0295	0.2613	0.2421
Trypanosoma cruzi	protein kinase A regulatory subunit	0.0083	0.0254	0.5
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0295	0.2613	0.2421
Brugia malayi	hypothetical protein	0.0295	0.2613	0.2421
Schistosoma mansoni	opsin-like receptor	0.0295	0.2613	0.2421
Schistosoma mansoni	adenoreceptor	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Schistosoma mansoni	voltage-gated potassium channel	0.0099	0.0433	0.0184
Mycobacterium tuberculosis	Conserved protein	0.0083	0.0254	0.5
Echinococcus granulosus	dro:myosuppressin receptor	0.0295	0.2613	0.2421
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Echinococcus granulosus	biogenic amine 5HT receptor	0.0295	0.2613	0.2421
Brugia malayi	neuropeptide F receptor	0.0295	0.2613	0.2421
Echinococcus granulosus	cyclic nucleotide gated cation channel	0.0124	0.0714	0.0472
Echinococcus granulosus	cyclic nucleotide gated cation channel	0.0124	0.0714	0.0472
Echinococcus multilocularis	G protein coupled receptor 139	0.0295	0.2613	0.2421
Trypanosoma brucei	protein kinase A regulatory subunit	0.0083	0.0254	1
Echinococcus granulosus	neuropeptide Y receptor	0.0295	0.2613	0.2421
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0295	0.2613	0.2421
Echinococcus multilocularis	potassium:sodium hyperpolarization activated	0.0124	0.0714	0.0472
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Echinococcus multilocularis	neuropeptide receptor A26	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0083	0.0254	0.5
Echinococcus granulosus	serotonin transporter	0.0093	0.0363	0.0112
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Schistosoma mansoni	opsin-like receptor	0.0295	0.2613	0.2421
Mycobacterium ulcerans	hypothetical protein	0.0083	0.0254	0.5
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0295	0.2613	0.2421
Mycobacterium ulcerans	transcriptional regulatory protein	0.0083	0.0254	0.5
Onchocerca volvulus		0.0295	0.2613	1
Schistosoma mansoni	neuropeptide F-like receptor	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0546	0.5398	0.5279
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0295	0.2613	0.2421
Brugia malayi	ORL1-like opioid receptor	0.0295	0.2613	0.2421
Mycobacterium ulcerans	transmembrane transport protein	0.0083	0.0254	0.5
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0295	0.2613	0.2421
Trypanosoma brucei	cAMP binding protein, putative	0.0083	0.0254	1
Plasmodium vivax	rap guanine nucleotide exchange factor, putative	0.0083	0.0254	0.5
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0093	0.0363	0.0112
Mycobacterium tuberculosis	Probable conserved transmembrane protein	0.0083	0.0254	0.5
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0295	0.2613	0.2421
Echinococcus multilocularis	g protein coupled receptor	0.0295	0.2613	0.2421
Echinococcus multilocularis	expressed conserved protein	0.0086	0.0281	0.0028
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Plasmodium vivax	CAMP-dependent protein kinase regulatory subunit, putative	0.0083	0.0254	0.5
Onchocerca volvulus		0.0295	0.2613	1
Mycobacterium ulcerans	hypothetical protein	0.0083	0.0254	0.5
Echinococcus multilocularis	neuropeptide Y receptor	0.0295	0.2613	0.2421
Schistosoma mansoni	amine GPCR	0.0295	0.2613	0.2421
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0295	0.2613	0.2421
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0295	0.2613	0.2421
Schistosoma mansoni	amine GPCR	0.0295	0.2613	0.2421
Loa Loa (eye worm)	solute carrier family 6 member 4	0.0093	0.0363	0.0112
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Onchocerca volvulus		0.0295	0.2613	1
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0295	0.2613	1
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0295	0.2613	0.2421
Echinococcus granulosus	cGMP dependent protein kinase 1	0.0086	0.0281	0.0028
Echinococcus granulosus	g-protein coupled receptor	0.0295	0.2613	0.2421
Mycobacterium leprae	Conserved hypothetical protein	0.0083	0.0254	0.5
Echinococcus multilocularis	cGMP dependent protein kinase 1	0.0086	0.0281	0.0028
Onchocerca volvulus		0.0295	0.2613	1
Chlamydia trachomatis	cAMP-dependent protein kinase regulatory subunit	0.0083	0.0254	0.5
Echinococcus granulosus	g protein coupled receptor	0.0295	0.2613	0.2421
Brugia malayi	hypothetical protein	0.0295	0.2613	0.2421
Trypanosoma brucei	cyclic nucleotide-binding domain containing protein, putative	0.0083	0.0254	1
Echinococcus granulosus	potassium:sodium hyperpolarization activated	0.0124	0.0714	0.0472
Schistosoma mansoni	neuropeptide receptor	0.0295	0.2613	0.2421
Loa Loa (eye worm)	neuropeptide F receptor	0.0295	0.2613	0.2421
Echinococcus multilocularis	g protein coupled receptor	0.0295	0.2613	0.2421
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0295	0.2613	0.2421
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0295	0.2613	0.2421
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0295	0.2613	0.2421
Schistosoma mansoni	hypothetical protein	0.0295	0.2613	0.2421
Loa Loa (eye worm)	G-protein coupled receptor	0.0295	0.2613	0.2421
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0295	0.2613	0.2421
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0295	0.2613	0.2421
Schistosoma mansoni	hypothetical protein	0.0295	0.2613	0.2421
Echinococcus granulosus	neuropeptide Y receptor	0.0295	0.2613	0.2421
Brugia malayi	larval opioid receptor	0.0295	0.2613	0.2421
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0295	0.2613	0.2421
Schistosoma mansoni	serine/threonine protein kinase	0.0086	0.0281	0.0028
Brugia malayi	AKH receptor	0.0295	0.2613	0.2421
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.0182	0.1356	0.1131
Loa Loa (eye worm)	hypothetical protein	0.0295	0.2613	0.2421
Onchocerca volvulus		0.0295	0.2613	1
Loa Loa (eye worm)	camk/mapkapk/mapkapk protein kinase	0.096	1	1
Echinococcus granulosus	allatostatin A receptor	0.0295	0.2613	0.2421
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0295	0.2613	0.2421
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0295	0.2613	0.2421
Schistosoma mansoni	voltage-gated potassium channel	0.0687	0.6964	0.6885
Onchocerca volvulus		0.0295	0.2613	1
Schistosoma mansoni	serine/threonine protein kinase	0.0086	0.0281	0.0028
Onchocerca volvulus		0.0295	0.2613	1
Echinococcus multilocularis	allatostatin A receptor	0.0295	0.2613	0.2421
Echinococcus multilocularis	g-protein coupled receptor	0.0295	0.2613	0.2421
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0295	0.2613	0.2421

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Search by Saint Jude

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 808123