Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.0043 | 0.1431 | 0.1431 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.1024 | 0.1024 |
Brugia malayi | Hint module family protein | 0.0052 | 0.1793 | 0.1793 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0043 | 0.1431 | 0.1431 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0302 | 0.0302 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0253 | 1 | 0.5 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0043 | 0.1431 | 0.1431 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0115 | 0.4393 | 0.4393 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0302 | 0.0302 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.1647 | 0.1647 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0253 | 1 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0043 | 0.1431 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0115 | 0.4393 | 0.4393 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0043 | 0.1431 | 0.5 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0043 | 0.1431 | 0.1431 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0302 | 0.0302 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0043 | 0.1431 | 0.1431 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0043 | 0.1431 | 0.1431 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0043 | 0.1431 | 0.1431 |
Echinococcus multilocularis | serotonin transporter | 0.0253 | 1 | 1 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.0043 | 0.1431 | 0.1431 |
Toxoplasma gondii | hypothetical protein | 0.0043 | 0.1431 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0253 | 1 | 1 |
Loa Loa (eye worm) | serotonin transporter b | 0.0253 | 1 | 1 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.0043 | 0.1431 | 0.1431 |
Plasmodium falciparum | amino acid transporter, putative | 0.0043 | 0.1431 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0139 | 0.5349 | 0.5349 |
Onchocerca volvulus | 0.0253 | 1 | 1 | |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.0043 | 0.1431 | 0.1431 |
Brugia malayi | MH2 domain containing protein | 0.0115 | 0.4393 | 0.4393 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0302 | 0.0302 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1431 | 0.1431 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0043 | 0.1431 | 0.1431 |
Loa Loa (eye worm) | hypothetical protein | 0.0253 | 1 | 1 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0043 | 0.1431 | 0.1431 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0043 | 0.1431 | 0.1431 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0043 | 0.1431 | 0.1431 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0302 | 0.0302 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0043 | 0.1431 | 0.1431 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0043 | 0.1431 | 0.1431 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0302 | 0.0302 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1431 | 0.1431 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0253 | 1 | 1 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0043 | 0.1431 | 0.1431 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.1647 | 0.1647 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0302 | 0.0302 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0302 | 0.0302 |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.0043 | 0.1431 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1431 | 0.1431 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.1024 | 0.1024 |
Toxoplasma gondii | hypothetical protein | 0.0043 | 0.1431 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.1024 | 0.1024 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0043 | 0.1431 | 0.1431 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0043 | 0.1431 | 0.1431 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0302 | 0.0302 |
Echinococcus granulosus | Desert hedgehog protein | 0.019 | 0.7463 | 0.7463 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.1647 | 0.1647 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0302 | 0.0302 |
Echinococcus granulosus | serotonin transporter | 0.0253 | 1 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0302 | 0.0302 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0043 | 0.1431 | 0.1431 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.0043 | 0.1431 | 0.1431 |
Loa Loa (eye worm) | hypothetical protein | 0.0253 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0302 | 0.0302 |
Echinococcus multilocularis | hedgehog | 0.019 | 0.7463 | 0.7463 |
Plasmodium falciparum | transporter, putative | 0.0043 | 0.1431 | 0.5 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0043 | 0.1431 | 0.5 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0043 | 0.1431 | 0.1431 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0043 | 0.1431 | 0.1431 |
Brugia malayi | hypothetical protein | 0.0043 | 0.1431 | 0.1431 |
Plasmodium vivax | amine transporter, putative | 0.0043 | 0.1431 | 0.5 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0043 | 0.1431 | 0.1431 |
Brugia malayi | Hint module family protein | 0.0052 | 0.1793 | 0.1793 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0043 | 0.1431 | 0.1431 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0253 | 1 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.1647 | 0.1647 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0043 | 0.1431 | 0.1431 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1431 | 0.1431 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0253 | 1 | 1 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0043 | 0.1431 | 0.1431 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0302 | 0.0302 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1431 | 0.1431 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1793 | 0.1793 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1431 | 0.1431 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1793 | 0.1793 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.1431 | 0.1431 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0043 | 0.1431 | 0.1431 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0043 | 0.1431 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0302 | 0.0302 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.