Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | cathepsin L-like precursor | 0.0103 | 0.0325 | 0.0331 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.014 | 0.0582 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0291 | 0.1638 | 0.8131 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0086 | 0.0204 | 0.0197 |
Brugia malayi | hypothetical protein | 0.0098 | 0.0285 | 0.029 |
Echinococcus multilocularis | cathepsin b | 0.0431 | 0.2613 | 0.2608 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Mycobacterium ulcerans | hypothetical protein | 0.0186 | 0.0903 | 1 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0098 | 0.0285 | 0.2144 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.007 | 0.0094 | 0.0091 |
Leishmania major | cathepsin L-like protease | 0.014 | 0.0582 | 0.0608 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0159 | 0.0713 | 0.0706 |
Brugia malayi | jmjC domain containing protein | 0.0229 | 0.1205 | 0.1249 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0098 | 0.0285 | 0.0278 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0159 | 0.0713 | 0.0735 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0291 | 0.1638 | 0.8131 |
Echinococcus multilocularis | cysteine protease | 0.014 | 0.0582 | 0.0575 |
Onchocerca volvulus | 0.014 | 0.0582 | 0.6176 | |
Loa Loa (eye worm) | doublecortin family protein | 0.0098 | 0.0285 | 0.029 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0103 | 0.0325 | 0.0681 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0354 | 0.2073 | 0.6028 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Echinococcus granulosus | tumor protein p63 | 0.0777 | 0.5032 | 0.5028 |
Echinococcus multilocularis | RUN | 0.0098 | 0.0285 | 0.0278 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.0938 | 0.4159 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0431 | 0.2613 | 0.2716 |
Giardia lamblia | Cathepsin B precursor | 0.0338 | 0.1968 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0188 | 0.0913 | 0.0945 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.014 | 0.0582 | 1 |
Loa Loa (eye worm) | fibroinase | 0.014 | 0.0582 | 0.0599 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0086 | 0.0204 | 0.0528 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0585 | 0.3693 | 0.3688 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0114 | 0.0398 | 0.0407 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0086 | 0.0204 | 0.0528 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.014 | 0.0582 | 0.1639 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.0938 | 0.4159 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.014 | 0.0582 | 0.0575 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Brugia malayi | Cathepsin L-like precursor | 0.014 | 0.0582 | 0.0599 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0585 | 0.3693 | 0.3688 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.143 | 0.96 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0135 | 0.0543 | 0.0558 |
Onchocerca volvulus | 0.0103 | 0.0325 | 0.341 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Echinococcus granulosus | cathepsin L | 0.0086 | 0.0204 | 0.0197 |
Trypanosoma brucei | cytochrome P450, putative | 0.0114 | 0.0398 | 0.0602 |
Loa Loa (eye worm) | hypothetical protein | 0.0547 | 0.3423 | 0.3561 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.0938 | 0.4159 |
Leishmania major | cathepsin L-like protease | 0.014 | 0.0582 | 0.0608 |
Leishmania major | cysteine peptidase A (CPA) | 0.014 | 0.0582 | 0.0608 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0229 | 0.1205 | 0.1199 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0291 | 0.1638 | 0.17 |
Leishmania major | cathepsin L-like protease | 0.014 | 0.0582 | 0.0608 |
Echinococcus granulosus | cathepsin b | 0.0431 | 0.2613 | 0.2608 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.014 | 0.0582 | 0.0575 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0547 | 0.3423 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.014 | 0.0582 | 1 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0098 | 0.0285 | 0.0278 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0285 | 0.029 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.014 | 0.0582 | 0.1639 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.0938 | 0.4159 |
Echinococcus granulosus | cathepsin b | 0.0431 | 0.2613 | 0.2608 |
Leishmania major | cathepsin L-like protease | 0.014 | 0.0582 | 0.0608 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0431 | 0.2613 | 0.2608 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Leishmania major | cathepsin L-like protease | 0.014 | 0.0582 | 0.0608 |
Schistosoma mansoni | lipoxygenase | 0.0585 | 0.3693 | 0.3688 |
Loa Loa (eye worm) | cathepsin B | 0.0338 | 0.1968 | 0.2044 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0338 | 0.1968 | 0.5478 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0167 | 0.0771 | 0.2196 |
Brugia malayi | Doublecortin family protein | 0.0098 | 0.0285 | 0.029 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0098 | 0.0285 | 0.2144 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0291 | 0.1638 | 0.8131 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0135 | 0.0543 | 0.0558 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0169 | 0.0169 |
Onchocerca volvulus | 0.014 | 0.0582 | 0.6176 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.0938 | 0.4159 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Onchocerca volvulus | 0.014 | 0.0582 | 0.6176 | |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.0582 | 0.0599 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.014 | 0.0582 | 0.0575 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0229 | 0.1205 | 0.1199 |
Onchocerca volvulus | 0.0114 | 0.0396 | 0.418 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Brugia malayi | Cytochrome P450 family protein | 0.0114 | 0.0398 | 0.0407 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0103 | 0.0325 | 0.3182 |
Schistosoma mansoni | hypothetical protein | 0.0098 | 0.0285 | 0.0278 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Schistosoma mansoni | rab6-interacting | 0.0098 | 0.0285 | 0.0278 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0431 | 0.2613 | 0.2608 |
Echinococcus granulosus | cathepsin l1 | 0.0103 | 0.0325 | 0.0318 |
Onchocerca volvulus | 0.014 | 0.0582 | 0.6176 | |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0547 | 0.3423 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.014 | 0.0582 | 0.0599 |
Brugia malayi | Cytochrome P450 family protein | 0.0114 | 0.0398 | 0.0407 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0114 | 0.0398 | 0.0407 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0086 | 0.0204 | 0.0206 |
Trypanosoma cruzi | cysteine protease, putative | 0.0086 | 0.0204 | 0.0528 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0159 | 0.0713 | 0.0706 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0159 | 0.0713 | 0.0706 |
Brugia malayi | hypothetical protein | 0.0098 | 0.0285 | 0.029 |
Echinococcus multilocularis | cathepsin L | 0.0086 | 0.0204 | 0.0197 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Brugia malayi | Cathepsin L-like precursor | 0.014 | 0.0582 | 0.0599 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0547 | 0.3423 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.014 | 0.0582 | 0.0599 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Leishmania major | cathepsin L-like protease | 0.014 | 0.0582 | 0.0608 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0191 | 0.0938 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.0325 | 0.0331 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0103 | 0.0325 | 0.0882 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0291 | 0.1638 | 0.8131 |
Onchocerca volvulus | 0.014 | 0.0582 | 0.6176 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0431 | 0.2613 | 0.2608 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.014 | 0.0582 | 0.0599 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.0325 | 0.0331 |
Leishmania major | cathepsin L-like protease | 0.014 | 0.0582 | 0.0608 |
Entamoeba histolytica | cysteine proteinase, putative | 0.014 | 0.0582 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0086 | 0.0204 | 0.0528 |
Onchocerca volvulus | 0.014 | 0.0582 | 0.6176 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.0938 | 0.4159 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.014 | 0.0582 | 0.0575 |
Toxoplasma gondii | cathepsin CPL | 0.014 | 0.0582 | 0.2957 |
Toxoplasma gondii | cathepsin B | 0.0338 | 0.1968 | 1 |
Onchocerca volvulus | 0.0098 | 0.0285 | 0.2989 | |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.014 | 0.0582 | 0.0575 |
Brugia malayi | Papain family cysteine protease containing protein | 0.014 | 0.0582 | 0.0599 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0354 | 0.2073 | 0.5538 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0114 | 0.0398 | 0.1098 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0396 | 0.0406 |
Schistosoma mansoni | polycystin 1-related | 0.0098 | 0.0285 | 0.0278 |
Loa Loa (eye worm) | hypothetical protein | 0.0431 | 0.2613 | 0.2716 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1487 | 1 | 1 |
Onchocerca volvulus | 0.0098 | 0.0285 | 0.2989 | |
Echinococcus multilocularis | cathepsin b | 0.0431 | 0.2613 | 0.2608 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.014 | 0.0582 | 0.0575 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1487 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0103 | 0.0325 | 0.0331 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0086 | 0.0204 | 0.0206 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0086 | 0.0204 | 0.0197 |
Echinococcus multilocularis | tumor protein p63 | 0.0777 | 0.5032 | 0.5028 |
Brugia malayi | Cathepsin L-like precursor | 0.014 | 0.0582 | 0.0599 |
Brugia malayi | follicle stimulating hormone receptor | 0.143 | 0.96 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.014 | 0.0582 | 0.0599 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Echinococcus granulosus | cathepsin l1 | 0.014 | 0.0582 | 0.0575 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0431 | 0.2613 | 0.2608 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Loa Loa (eye worm) | ctsf protein | 0.014 | 0.0582 | 0.0599 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0103 | 0.0325 | 0.0681 |
Onchocerca volvulus | Cathepsin L homolog | 0.014 | 0.0582 | 0.6176 |
Schistosoma mansoni | lipoxygenase | 0.0409 | 0.2462 | 0.2456 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0291 | 0.1638 | 0.8131 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.014 | 0.0582 | 0.1173 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.014 | 0.0582 | 0.1639 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0338 | 0.1968 | 1 |
Schistosoma mansoni | jumonji domain containing protein | 0.0206 | 0.1045 | 0.1038 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.0325 | 0.0331 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0431 | 0.2613 | 0.7615 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.023 | 0.0232 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.014 | 0.0582 | 0.0599 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0086 | 0.0204 | 0.0197 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0086 | 0.0204 | 0.0197 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0103 | 0.0325 | 0.0331 |
Plasmodium vivax | vivapain-2 | 0.014 | 0.0582 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0103 | 0.0325 | 0.0318 |
Brugia malayi | MH2 domain containing protein | 0.0135 | 0.0543 | 0.0558 |
Onchocerca volvulus | Cathepsin L homolog | 0.014 | 0.0582 | 0.6176 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.014 | 0.0582 | 0.0575 |
Brugia malayi | jmjC domain containing protein | 0.0159 | 0.0713 | 0.0735 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0338 | 0.1968 | 0.1962 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0167 | 0.0771 | 0.1761 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Giardia lamblia | Cathepsin B precursor | 0.0338 | 0.1968 | 0.5 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.0547 | 0.3423 | 0.3561 |
Entamoeba histolytica | cysteine proteinase, putative | 0.014 | 0.0582 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.101 | 0.4567 |
Leishmania major | cathepsin L-like protease | 0.014 | 0.0582 | 0.0608 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.014 | 0.0582 | 0.1639 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0114 | 0.0398 | 0.0407 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0285 | 0.029 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0191 | 0.0938 | 0.4159 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0291 | 0.1638 | 0.17 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.014 | 0.0582 | 0.0575 |
Echinococcus granulosus | cysteine protease | 0.0086 | 0.0204 | 0.0197 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0098 | 0.0285 | 0.0278 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0114 | 0.0396 | 0.0389 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0167 | 0.0771 | 0.1234 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.014 | 0.0582 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0354 | 0.2073 | 0.6028 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0098 | 0.0285 | 0.0278 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0114 | 0.0398 | 0.1098 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0354 | 0.2073 | 0.5806 |
Schistosoma mansoni | loxhd1 | 0.0098 | 0.0285 | 0.0278 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0098 | 0.0285 | 0.0278 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Loa Loa (eye worm) | cysteine protease | 0.014 | 0.0582 | 0.0599 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0086 | 0.0204 | 0.0528 |
Giardia lamblia | Cathepsin B precursor | 0.0338 | 0.1968 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0291 | 0.1638 | 0.8131 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0159 | 0.0713 | 0.0706 |
Onchocerca volvulus | 0.014 | 0.0582 | 0.6176 | |
Plasmodium vivax | vivapain-2 | 0.014 | 0.0582 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.014 | 0.0582 | 0.1639 |
Echinococcus multilocularis | cysteine protease | 0.014 | 0.0582 | 0.0575 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.014 | 0.0582 | 0.2141 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0186 | 0.0903 | 0.5 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0098 | 0.0285 | 0.0278 |
Schistosoma mansoni | rab6-interacting | 0.0098 | 0.0285 | 0.0278 |
Onchocerca volvulus | Cathepsin F homolog | 0.014 | 0.0582 | 0.6176 |
Echinococcus granulosus | RUN | 0.0098 | 0.0285 | 0.0278 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.101 | 0.4567 |
Brugia malayi | Cathepsin L-like precursor | 0.0103 | 0.0325 | 0.0331 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0338 | 0.1968 | 0.5717 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0338 | 0.1968 | 0.5189 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 0.006 mg kg-1 | Compound was tested for the antagonistic activity against amphetamine-induced stereotypy in rat. | ChEMBL. | 3941416 |
IC50 (binding) | = 13 nM | Inhibition of [3H]-spiroperidol (0.5 nM) binding to dopamine receptor from rat striatal membrane. | ChEMBL. | 3941416 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.