Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0043 | 0.0419 | 0.041 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0048 | 0.0488 | 0.3296 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0407 | 0.0473 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0076 | 0.0088 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.002 | 0.0076 | 0.0076 |
Echinococcus multilocularis | lamin | 0.0032 | 0.0255 | 0.0246 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.002 | 0.0076 | 0.0076 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.002 | 0.0076 | 0.0067 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.002 | 0.0072 | 0.0304 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.002 | 0.0076 | 0.0066 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0022 | 0.0111 | 0.0101 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0165 | 0.1418 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.004 | 0.0377 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0042 | 0.0407 | 0.0462 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0111 | 0.0129 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0076 | 0.0088 |
Schistosoma mansoni | thyroid hormone receptor | 0.0042 | 0.0407 | 0.0398 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0165 | 0.0733 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.002 | 0.0076 | 0.0088 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0076 | 0.0088 |
Toxoplasma gondii | Hsp90 domain-containing protein | 0.0158 | 0.2122 | 1 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.002 | 0.0076 | 0.0067 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.005 | 0.0517 | 0.0589 |
Brugia malayi | nuclear hormone receptor | 0.0042 | 0.0407 | 0.0462 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0048 | 0.0488 | 0.3388 |
Echinococcus multilocularis | jun protein | 0.0184 | 0.252 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0145 | 0.1931 | 0.2233 |
Brugia malayi | small heat shock protein | 0.0595 | 0.8615 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.002 | 0.0076 | 0.0067 |
Mycobacterium leprae | PROBABLE HYDROLASE | 0.0111 | 0.1421 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0042 | 0.0407 | 0.0462 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0151 | 0.203 | 0.2357 |
Echinococcus multilocularis | heat shock protein 75 kDa, mitochondrial | 0.0017 | 0.0029 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0246 | 0.0286 |
Onchocerca volvulus | 0.0145 | 0.1931 | 0.6939 | |
Echinococcus multilocularis | geminin | 0.0336 | 0.4765 | 0.476 |
Loa Loa (eye worm) | hypothetical protein | 0.0111 | 0.1421 | 0.165 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0048 | 0.0488 | 0.4383 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0042 | 0.0407 | 0.0473 |
Brugia malayi | Matrixin family protein | 0.0219 | 0.3039 | 0.3521 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0042 | 0.0407 | 0.0473 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0076 | 0.0076 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.002 | 0.0076 | 0.0076 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0048 | 0.0491 | 0.0483 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0111 | 0.0129 |
Echinococcus granulosus | matrix metallopeptidase 7 M10 family | 0.033 | 0.4682 | 0.4677 |
Trypanosoma brucei | heat shock protein 84, putative | 0.0017 | 0.0029 | 0.0177 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0022 | 0.0111 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0309 | 0.0359 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.002 | 0.0076 | 0.0168 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0076 | 0.0088 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0688 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0111 | 0.0117 |
Echinococcus granulosus | geminin | 0.0336 | 0.4765 | 0.476 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0089 | 0.1101 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0076 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0595 | 0.8615 | 1 |
Schistosoma mansoni | jun-related protein | 0.015 | 0.2006 | 0.1998 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.002 | 0.0076 | 0.0067 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0048 | 0.0491 | 0.056 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.002 | 0.0076 | 0.0066 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0022 | 0.0111 | 0.0102 |
Echinococcus granulosus | lamin | 0.0032 | 0.0255 | 0.0246 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0048 | 0.0488 | 0.4282 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0042 | 0.0407 | 0.0462 |
Echinococcus granulosus | heat shock protein 75 kDa mitochondrial | 0.0017 | 0.0029 | 0.0021 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.203 | 0.2357 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0407 | 0.0473 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0076 | 0.0088 |
Onchocerca volvulus | 0.0032 | 0.0255 | 0.0822 | |
Entamoeba histolytica | protein kinase, putative | 0.0089 | 0.1101 | 1 |
Brugia malayi | ecdysone receptor | 0.002 | 0.0076 | 0.0076 |
Onchocerca volvulus | 0.0129 | 0.1691 | 0.6064 | |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0042 | 0.0407 | 0.0462 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0184 | 0.252 | 0.2513 |
Mycobacterium ulcerans | hydrolase | 0.0111 | 0.1421 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0034 | 0.028 | 0.1913 |
Toxoplasma gondii | exonuclease III APE | 0.002 | 0.0072 | 0.0292 |
Schistosoma mansoni | matrix metallopeptidase-7 (M10 family) | 0.0091 | 0.1128 | 0.1119 |
Onchocerca volvulus | Matrilysin homolog | 0.0201 | 0.277 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0042 | 0.0407 | 0.0462 |
Loa Loa (eye worm) | intermediate filament protein | 0.0032 | 0.0255 | 0.0296 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.002 | 0.0076 | 0.0067 |
Schistosoma mansoni | hypothetical protein | 0.0104 | 0.1318 | 0.1309 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0042 | 0.0407 | 0.0399 |
Brugia malayi | Protein kinase domain containing protein | 0.0089 | 0.1101 | 0.1268 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0089 | 0.1101 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0089 | 0.1101 | 0.1092 |
Onchocerca volvulus | 0.0091 | 0.1128 | 0.4007 | |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0043 | 0.0419 | 0.041 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0111 | 0.0117 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0042 | 0.0407 | 0.0399 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0076 | 0.0066 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.002 | 0.0076 | 0.0067 |
Schistosoma mansoni | hypothetical protein | 0.0336 | 0.4765 | 0.476 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0165 | 0.1418 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1128 | 0.1309 |
Echinococcus multilocularis | dual specificity | 0.0089 | 0.1101 | 0.1093 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0165 | 0.0733 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0072 | 0.1218 |
Schistosoma mansoni | hypothetical protein | 0.015 | 0.2006 | 0.1998 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0165 | 0.0733 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0491 | 0.0571 |
Echinococcus granulosus | FTZ F1 alpha | 0.0042 | 0.0407 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0076 | 0.0088 |
Echinococcus multilocularis | lamin dm0 | 0.0032 | 0.0255 | 0.0246 |
Echinococcus granulosus | lamin dm0 | 0.0032 | 0.0255 | 0.0246 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0042 | 0.0407 | 0.0473 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1128 | 0.1309 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0036 | 0.0309 | 0.1416 |
Onchocerca volvulus | Matrix metalloproteinase homolog | 0.0201 | 0.277 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0336 | 0.4765 | 0.476 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0036 | 0.0309 | 0.1416 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0517 | 0.0507 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0048 | 0.0491 | 0.056 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.002 | 0.0076 | 0.0076 |
Brugia malayi | Hsp90 protein | 0.0017 | 0.0029 | 0.0022 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0042 | 0.0407 | 0.138 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0048 | 0.0488 | 0.3388 |
Schistosoma mansoni | zinc finger protein | 0.002 | 0.0076 | 0.0066 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0076 | 0.0067 |
Schistosoma mansoni | hypothetical protein | 0.0113 | 0.1456 | 0.1448 |
Echinococcus granulosus | endoplasmin | 0.0017 | 0.0029 | 0.0021 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0022 | 0.0111 | 0.0117 |
Schistosoma mansoni | thyroid hormone receptor | 0.0042 | 0.0407 | 0.0398 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0042 | 0.0407 | 0.0399 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0089 | 0.1101 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0042 | 0.0407 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0076 | 0.0088 |
Schistosoma mansoni | hypothetical protein | 0.0129 | 0.1691 | 0.1683 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0048 | 0.0488 | 0.3296 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.001 | 0.0001 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0042 | 0.0407 | 0.0462 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0072 | 0.0062 |
Loa Loa (eye worm) | matrixin family protein | 0.0219 | 0.3039 | 0.3528 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0042 | 0.0407 | 0.0473 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.0072 | 0.0083 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0042 | 0.0407 | 0.138 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0076 | 0.0067 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.0072 | 0.0063 |
Onchocerca volvulus | 0.005 | 0.0517 | 0.1779 | |
Echinococcus multilocularis | GPCR, family 2 | 0.0048 | 0.0491 | 0.0483 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0022 | 0.0111 | 0.0102 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0488 | 0.0567 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0043 | 0.0419 | 0.0486 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0036 | 0.0309 | 0.2118 |
Trypanosoma cruzi | heat shock protein, putative | 0.0017 | 0.0029 | 0.0177 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0042 | 0.0407 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.1094 | 0.127 |
Brugia malayi | nuclear receptor RXR | 0.002 | 0.0076 | 0.0076 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0042 | 0.0407 | 0.0473 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.002 | 0.0076 | 0.0067 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0165 | 0.0733 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0072 | 0.1218 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0042 | 0.0407 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0309 | 0.0359 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0034 | 0.028 | 0.1913 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1128 | 0.1309 |
Mycobacterium ulcerans | hypothetical protein | 0.0048 | 0.0488 | 0.3296 |
Leishmania major | heat shock protein, putative | 0.0017 | 0.0029 | 0.0177 |
Schistosoma mansoni | survival motor neuron protein | 0.005 | 0.0517 | 0.0507 |
Plasmodium vivax | heat shock protein, putative | 0.0158 | 0.2122 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0042 | 0.0407 | 0.0462 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0042 | 0.0407 | 0.0462 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0048 | 0.0491 | 0.0483 |
Mycobacterium tuberculosis | Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) | 0.0017 | 0.0029 | 0.0137 |
Brugia malayi | nuclear receptor NHR-67 | 0.002 | 0.0076 | 0.0076 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.001 | 0.0001 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0048 | 0.0488 | 0.3296 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.001 | 0.0001 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0042 | 0.0407 | 0.0462 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0491 | 0.0482 |
Schistosoma mansoni | heat shock protein | 0.0017 | 0.0029 | 0.0019 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0165 | 0.1418 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0048 | 0.0488 | 0.3296 |
Schistosoma mansoni | coup transcription factor | 0.0042 | 0.0407 | 0.0398 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0034 | 0.028 | 0.1913 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.004 | 0.0377 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0072 | 0.0292 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0491 | 0.0482 |
Loa Loa (eye worm) | heat shock protein 75 | 0.0017 | 0.0029 | 0.0034 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0042 | 0.0407 | 0.0399 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0042 | 0.0407 | 0.0399 |
Echinococcus multilocularis | musashi | 0.0032 | 0.0255 | 0.0246 |
Onchocerca volvulus | Matrilysin homolog | 0.0091 | 0.1128 | 0.4007 |
Schistosoma mansoni | nuclear receptor | 0.002 | 0.0076 | 0.0066 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0042 | 0.0407 | 0.0398 |
Loa Loa (eye worm) | hypothetical protein | 0.0179 | 0.2444 | 0.2838 |
Loa Loa (eye worm) | matrixin family protein | 0.0201 | 0.277 | 0.3215 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0309 | 0.0359 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0042 | 0.0407 | 0.0462 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0165 | 0.0191 |
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.033 | 0.4682 | 0.4677 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0076 | 0.0088 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0042 | 0.0407 | 0.0399 |
Schistosoma mansoni | matrix metallopeptidase-9 (M10 family) | 0.0096 | 0.1202 | 0.1194 |
Brugia malayi | bZIP transcription factor family protein | 0.0184 | 0.252 | 0.2916 |
Loa Loa (eye worm) | DR-78 | 0.002 | 0.0076 | 0.0088 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.002 | 0.0076 | 0.0067 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0491 | 0.0482 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0111 | 0.0129 |
Echinococcus multilocularis | endoplasmin | 0.0017 | 0.0029 | 0.0021 |
Loa Loa (eye worm) | matrix metalloproteinase | 0.0091 | 0.1128 | 0.1309 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0048 | 0.0488 | 0.3296 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0407 | 0.0473 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0042 | 0.0407 | 0.0398 |
Entamoeba histolytica | protein kinase, putative | 0.0089 | 0.1101 | 1 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0048 | 0.0488 | 0.4282 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.001 | 0.0001 |
Toxoplasma gondii | heat shock protein 75, putative | 0.0017 | 0.0029 | 0.0092 |
Brugia malayi | hypothetical protein | 0.002 | 0.0076 | 0.0076 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0032 | 0.0255 | 0.0284 |
Brugia malayi | tailless protein | 0.002 | 0.0076 | 0.0076 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0072 | 0.0062 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0048 | 0.0488 | 0.3296 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0042 | 0.0407 | 0.0462 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0491 | 0.0482 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0009 | 0.001 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0042 | 0.0407 | 0.0398 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0036 | 0.0309 | 0.2009 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0076 | 0.0076 |
Brugia malayi | hypothetical protein | 0.002 | 0.0076 | 0.0076 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0076 | 0.0066 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0047 | 0.0477 | 0.0468 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0407 | 0.0473 |
Onchocerca volvulus | 0.0032 | 0.0255 | 0.0822 | |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0334 | 0.0388 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0165 | 0.1418 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0089 | 0.1101 | 1 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0165 | 0.018 |
Brugia malayi | Cytochrome P450 family protein | 0.0057 | 0.0625 | 0.0714 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0042 | 0.0407 | 0.0399 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0047 | 0.0477 | 0.0468 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0042 | 0.0407 | 0.0462 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.1094 | 0.127 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.0072 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0076 | 0.0088 |
Brugia malayi | Matrix metalloprotease, N-terminal domain containing protein | 0.0111 | 0.1421 | 0.164 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0072 | 0.0565 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0048 | 0.0491 | 0.0483 |
Onchocerca volvulus | 0.0048 | 0.0488 | 0.1675 | |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0048 | 0.0488 | 0.3296 |
Schistosoma mansoni | intermediate filament proteins | 0.0032 | 0.0255 | 0.0245 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.0072 | 0.0063 |
Echinococcus granulosus | intermediate filament protein | 0.0032 | 0.0255 | 0.0246 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.002 | 0.0072 | 1 |
Echinococcus granulosus | jun protein | 0.0184 | 0.252 | 0.2513 |
Brugia malayi | nuclear receptor RXR | 0.0022 | 0.0111 | 0.0117 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0688 | 1 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0042 | 0.0407 | 0.0462 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.1318 | 0.153 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.0017 | 0.0029 | 0.0177 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0184 | 0.252 | 0.2513 |
Echinococcus granulosus | dual specificity | 0.0089 | 0.1101 | 0.1093 |
Schistosoma mansoni | lamin | 0.0032 | 0.0255 | 0.0245 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0072 | 0.0292 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0034 | 0.028 | 0.1913 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.002 | 0.0072 | 0.0395 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0089 | 0.1101 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0042 | 0.0407 | 0.0462 |
Schistosoma mansoni | nuclear receptor | 0.002 | 0.0076 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0407 | 0.0473 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.002 | 0.0072 | 0.0565 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0042 | 0.0407 | 0.0462 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0042 | 0.0407 | 0.0399 |
Schistosoma mansoni | nuclear hormone receptor | 0.0042 | 0.0407 | 0.0398 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0104 | 0.1318 | 0.152 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0309 | 0.0359 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0048 | 0.0488 | 0.4383 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0255 | 0.0296 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0032 | 0.0255 | 0.0296 |
Onchocerca volvulus | 0.0042 | 0.0407 | 0.138 | |
Onchocerca volvulus | Bile acid receptor homolog | 0.0042 | 0.0407 | 0.138 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.002 | 0.0076 | 0.0067 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.0488 | 0.0556 |
Schistosoma mansoni | lamin | 0.0032 | 0.0255 | 0.0245 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.002 | 0.0076 | 0.0168 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0017 | 0.0034 | 0.0039 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0048 | 0.0491 | 0.0483 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0017 | 0.0034 | 0.0028 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0042 | 0.0407 | 0.0462 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0042 | 0.0407 | 0.0399 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0042 | 0.0407 | 0.0398 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0089 | 0.1101 | 0.1278 |
Brugia malayi | intermediate filament protein | 0.0032 | 0.0255 | 0.0284 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.0488 | 0.0556 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0111 | 0.0129 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0057 | 0.0625 | 0.0725 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0042 | 0.0407 | 0.0399 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.002 | 0.0076 | 0.0088 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0042 | 0.0407 | 0.0398 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0042 | 0.0407 | 0.0462 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.002 | 0.0076 | 0.0088 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.0072 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0048 | 0.0488 | 0.4282 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0407 | 0.0473 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0151 | 0.203 | 0.2348 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0309 | 0.0359 |
Brugia malayi | Nuclear hormone receptor E75 | 0.002 | 0.0076 | 0.0076 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.0488 | 0.0556 |
Brugia malayi | Matrixin family protein | 0.0091 | 0.1128 | 0.1299 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0042 | 0.0407 | 0.0398 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0022 | 0.0111 | 0.0129 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0028 | 0.0021 |
Entamoeba histolytica | hypothetical protein | 0.0089 | 0.1101 | 1 |
Brugia malayi | Matrixin family protein | 0.0091 | 0.1128 | 0.1299 |
Brugia malayi | Matrixin family protein | 0.0091 | 0.1128 | 0.1299 |
Onchocerca volvulus | 0.002 | 0.0076 | 0.0168 | |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0076 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0076 | 0.0088 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0042 | 0.0407 | 0.0399 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0042 | 0.0407 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.0243 | 0.3396 | 0.3943 |
Plasmodium falciparum | heat shock protein 90, putative | 0.0158 | 0.2122 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0072 | 0.0565 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0048 | 0.0488 | 0.3296 |
Brugia malayi | hypothetical protein | 0.0243 | 0.3396 | 0.3936 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0076 | 0.0088 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0048 | 0.0488 | 0.4383 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0151 | 0.203 | 0.2348 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0488 | 0.0567 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0042 | 0.0407 | 0.0473 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0042 | 0.0407 | 0.0399 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0036 | 0.0309 | 0.5 |
Brugia malayi | Matrixin family protein | 0.0091 | 0.1128 | 0.1299 |
Brugia malayi | Nuclear hormone receptor E75 | 0.002 | 0.0076 | 0.0076 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.002 | 0.0076 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0111 | 0.0129 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.001 | 0.0012 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.002 | 0.0072 | 0.0565 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0048 | 0.0491 | 0.0571 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0042 | 0.0407 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0407 | 0.0473 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0042 | 0.0407 | 0.0473 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0.0072 | 0.0437 |
Brugia malayi | Hemopexin family protein | 0.0129 | 0.1691 | 0.1954 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0048 | 0.0488 | 0.3296 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0043 | 0.0419 | 0.0475 |
Onchocerca volvulus | 0.002 | 0.0076 | 0.0168 | |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0243 | 0.3396 | 0.3391 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0407 | 0.0473 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0042 | 0.0407 | 0.0462 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0022 | 0.0111 | 0.0117 |
Echinococcus granulosus | GPCR family 2 | 0.0048 | 0.0491 | 0.0483 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0042 | 0.0407 | 0.0398 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0042 | 0.0407 | 0.0398 |
Mycobacterium tuberculosis | Probable peptidoglycan hydrolase | 0.0111 | 0.1421 | 1 |
Brugia malayi | steroid hormone receptor | 0.0042 | 0.0407 | 0.0462 |
Brugia malayi | conserved hypotetical protein | 0.002 | 0.0076 | 0.0076 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0042 | 0.0407 | 0.0398 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0243 | 0.3396 | 0.3391 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0042 | 0.0407 | 0.0473 |
Plasmodium vivax | heat shock protein 90, putative | 0.0017 | 0.0029 | 0.0092 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0488 | 0.0567 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.0072 | 0.0072 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.002 | 0.0076 | 0.0067 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.