Detailed information for compound 872005

Basic information

Technical information
  • TDR Targets ID: 872005
  • Name: T5462152
  • MW: 339.344 | Formula: C17H10FN3O2S
  • H donors: 1 H acceptors: 2 LogP: 2.82 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1cccc(c1)NC(=O)c1sc2c(c1)c(=O)n1c(n2)cccc1
  • InChi: 1S/C17H10FN3O2S/c18-10-4-3-5-11(8-10)19-15(22)13-9-12-16(24-13)20-14-6-1-2-7-21(14)17(12)23/h1-9H,(H,19,22)
  • InChiKey: UHDHSSSAIHWYLJ-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • ZINC00426863
  • EU-0090842

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0029 0.0559 0.9344
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0097 0.2234 0.2948
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0224 0.3749
Mycobacterium ulcerans sugar transporter 0.0014 0.0177 0.258
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0384 0.5587
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0384 0.6416
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.003 0.0574 0.0574
Brugia malayi hypothetical protein 0.0014 0.0177 0.0344
Plasmodium falciparum lysine--tRNA ligase 0.0022 0.0375 0.0375
Leishmania major glucose transporter, lmgt1 0.003 0.0583 0.8491
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0097 0.2234 0.2948
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0018 0.0294 0.4923
Echinococcus multilocularis solute carrier family 22 0.0014 0.0177 0.0234
Leishmania major glucose transporter/membrane transporter D2, putative 0.003 0.0583 0.8491
Leishmania major protein kinase, putative 0.003 0.0574 0.8354
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.003 0.0574 0.1115
Echinococcus multilocularis lysyl tRNA synthetase 0.0022 0.0375 0.0495
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Trypanosoma cruzi hexose transporter, putative 0.003 0.0583 0.8491
Echinococcus granulosus lipoxygenase domain containing protein 0.0018 0.0292 0.0385
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.003 0.0574 0.0757
Loa Loa (eye worm) hypothetical protein 0.0029 0.0559 0.1086
Schistosoma mansoni lipoxygenase 0.0018 0.0292 0.1308
Entamoeba histolytica acyl-CoA synthetase, putative 0.0022 0.0384 0.5587
Leishmania major 4-coumarate:coa ligase-like protein 0.0022 0.0384 0.5587
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0177 0.0793
Leishmania major glucose transporter, lmgt2 0.003 0.0583 0.8491
Brugia malayi Cam kinase protein 1 0.003 0.0574 0.1115
Leishmania major lysyl-tRNA synthetase, putative 0.0022 0.0375 0.546
Entamoeba histolytica protein kinase, putative 0.003 0.0574 0.8354
Brugia malayi major facilitator superfamily protein 0.0014 0.0177 0.0344
Loa Loa (eye worm) hypothetical protein 0.0016 0.0246 0.0479
Toxoplasma gondii sugar transporter ST3 0.0014 0.0177 0.0268
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Echinococcus granulosus lamin dm0 0.0025 0.0458 0.0605
Plasmodium falciparum proline--tRNA ligase 0.0034 0.0678 0.0678
Entamoeba histolytica acyl-CoA synthetase, putative 0.0022 0.0384 0.5587
Echinococcus multilocularis inositol monophosphatase 1 0.0034 0.0687 0.0906
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Brugia malayi Sugar transporter family protein 0.0014 0.0177 0.0344
Plasmodium vivax lysine--tRNA ligase, putative 0.0022 0.0375 0.0375
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0012 0.0139 0.0183
Brugia malayi lysyl-tRNA synthetase 0.0022 0.0375 0.0729
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0034 0.0687 1
Onchocerca volvulus 0.0025 0.0458 0.4708
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0029 0.0559 0.8138
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.003 0.0574 0.0757
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0097 0.2234 0.2948
Loa Loa (eye worm) hypothetical protein 0.0012 0.0139 0.0269
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0344
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0344
Loa Loa (eye worm) hypothetical protein 0.0018 0.0292 0.0568
Onchocerca volvulus 0.0014 0.0177 0.182
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0224 0.3749
Onchocerca volvulus 0.0014 0.0177 0.182
Echinococcus multilocularis Polycystic kidney disease protein 0.0018 0.0292 0.0385
Brugia malayi Inositol-1 0.0034 0.0687 0.1334
Schistosoma mansoni hypothetical protein 0.0097 0.2234 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0246 0.0479
Schistosoma mansoni glucose transport protein 0.0097 0.2234 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0224 0.3749
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0022 0.0384 0.6416
Plasmodium vivax CDK-related protein kinase 6, putative 0.041 1 1
Echinococcus multilocularis General substrate transporter 0.0083 0.1898 0.2504
Brugia malayi hypothetical protein 0.0018 0.0292 0.0568
Echinococcus granulosus Polycystic kidney disease protein 0.0018 0.0292 0.0385
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0097 0.2234 0.2948
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0014 0.0177 0.0793
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0384 0.5587
Schistosoma mansoni sugar transporter 0.0014 0.0177 0.0793
Plasmodium falciparum acyl-CoA synthetase 0.0016 0.0246 0.0246
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.003 0.0574 0.0574
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0022 0.0375 0.546
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0034 0.0678 0.1026
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0012 0.0139 0.0183
Onchocerca volvulus 0.0014 0.0177 0.182
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0014 0.0177 0.258
Trypanosoma cruzi hexose transporter, putative 0.003 0.0583 0.8491
Trypanosoma brucei glucose transporter, putative 0.003 0.0583 0.8491
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0344
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0018 0.0294 0.4923
Brugia malayi follicle stimulating hormone receptor 0.0214 0.5145 1
Trichomonas vaginalis sugar transport protein, putative 0.0014 0.0177 0.0793
Onchocerca volvulus 0.0025 0.0458 0.4708
Plasmodium vivax multidomain scavenger receptor, putative 0.0018 0.0292 0.0292
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Brugia malayi major facilitator superfamily protein 0.0014 0.0177 0.0344
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0016 0.0246 0.3588
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0019 0.0309 0.1383
Schistosoma mansoni sugar transporter 0.0014 0.0177 0.0793
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0384 0.0745
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0384 0.0745
Schistosoma mansoni serine/threonine protein kinase 0.003 0.0574 0.2567
Schistosoma mansoni loxhd1 0.0018 0.0292 0.1308
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0014 0.0177 0.2963
Leishmania major myo-inositol/proton symporter (MIT) 0.0014 0.0177 0.258
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0177 0.0344
Loa Loa (eye worm) major facilitator superfamily transporter 0.0014 0.0177 0.0344
Schistosoma mansoni intermediate filament proteins 0.0025 0.0458 0.2051
Echinococcus multilocularis synaptic vesicle 2 protein 0.0014 0.0177 0.0234
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0097 0.2234 0.2948
Loa Loa (eye worm) inositol-1 0.0034 0.0687 0.1334
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0034 0.0687 1
Plasmodium falciparum calcium-dependent protein kinase 4 0.003 0.0574 0.0574
Schistosoma mansoni rab6-interacting 0.0018 0.0292 0.1308
Plasmodium falciparum protein kinase 7 0.0273 0.6604 0.6604
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0344
Entamoeba histolytica hypothetical protein 0.0022 0.0375 0.546
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.003 0.0574 0.0574
Mycobacterium ulcerans prolyl-tRNA synthetase 0.001 0.0094 0.1372
Onchocerca volvulus 0.0014 0.0177 0.182
Echinococcus multilocularis calcium dependent protein kinase 0.0028 0.0528 0.0697
Schistosoma mansoni lipoxygenase 0.0051 0.1105 0.4946
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0014 0.0177 0.0177
Onchocerca volvulus 0.0014 0.0177 0.182
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Trypanosoma cruzi hexose transporter, putative 0.003 0.0583 0.8491
Leishmania major 4-coumarate:coa ligase-like protein 0.0022 0.0384 0.5587
Brugia malayi AMP-binding enzyme family protein 0.0022 0.0384 0.0745
Loa Loa (eye worm) hypothetical protein 0.0012 0.0127 0.0247
Loa Loa (eye worm) doublecortin family protein 0.0018 0.0292 0.0568
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0029 0.0559 0.2501
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0034 0.0678 0.9871
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0177 0.0793
Onchocerca volvulus 0.0046 0.0973 1
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0034 0.0687 1
Echinococcus granulosus Sugar transporter ERD6 protein 0.0014 0.0177 0.0234
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0029 0.0559 0.0737
Trichomonas vaginalis glucose transporter, putative 0.003 0.0583 0.2609
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0156 0.3709 0.5616
Mycobacterium ulcerans hypothetical protein 0.0022 0.0384 0.5587
Brugia malayi Sugar transporter family protein 0.0097 0.2234 0.4342
Giardia lamblia Lysyl-tRNA synthetase 0.0022 0.0375 0.5182
Schistosoma mansoni lamin 0.0025 0.0458 0.2051
Echinococcus granulosus solute carrier family 22 0.0014 0.0177 0.0234
Toxoplasma gondii sugar transporter ST2 0.0014 0.0177 0.0268
Chlamydia trachomatis lysine--tRNA ligase 0.0022 0.0375 1
Trypanosoma cruzi hexose transporter 0.003 0.0583 0.8491
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Trypanosoma brucei glucose transporter 1E 0.003 0.0583 0.8491
Echinococcus granulosus General substrate transporter 0.0083 0.1898 0.2504
Toxoplasma gondii protein kinase, putative 0.0273 0.6604 1
Schistosoma mansoni rab6-interacting 0.0018 0.0292 0.1308
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Loa Loa (eye worm) hypothetical protein 0.0012 0.0127 0.0247
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0097 0.2234 0.2948
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0177 0.0793
Echinococcus multilocularis lipoxygenase domain containing protein 0.0018 0.0292 0.0385
Echinococcus multilocularis lamin dm0 0.0025 0.0458 0.0605
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0013 0.0171 0.0333
Echinococcus multilocularis lipoxygenase domain containing protein 0.0018 0.0292 0.0385
Trichomonas vaginalis sugar transporter, putative 0.003 0.0583 0.2609
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Schistosoma mansoni lamin 0.0025 0.0458 0.2051
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0029 0.0559 0.0737
Trypanosoma brucei glucose transporter, putative 0.003 0.0583 0.8491
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0344
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0014 0.0177 0.258
Entamoeba histolytica acyl-coA synthetase, putative 0.0022 0.0384 0.5587
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0344
Schistosoma mansoni sugar transporter 0.0014 0.0177 0.0793
Plasmodium vivax calcium-dependent protein kinase, putative 0.003 0.0574 0.0574
Brugia malayi hypothetical protein 0.0014 0.0177 0.0344
Echinococcus multilocularis tumor protein p63 0.0312 0.758 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0344
Toxoplasma gondii lysine-tRNA ligase 0.0022 0.0375 0.0568
Echinococcus granulosus lamin 0.0025 0.0458 0.0605
Trypanosoma cruzi hexose transporter, putative 0.0014 0.0177 0.258
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0034 0.0687 1
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0029 0.0559 0.1086
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0583 0.2609
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Trypanosoma brucei THT1 - hexose transporter, putative 0.003 0.0583 0.8491
Schistosoma mansoni polycystin 1-related 0.0018 0.0292 0.1308
Trypanosoma cruzi glucose transporter, putative 0.0014 0.0177 0.258
Trichomonas vaginalis glucose transporter, putative 0.0014 0.0177 0.0793
Plasmodium vivax sugar transporter, putative 0.0014 0.0177 0.0177
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0029 0.0559 0.2501
Brugia malayi Intermediate filament tail domain containing protein 0.0025 0.0458 0.0891
Plasmodium falciparum calcium-dependent protein kinase 2 0.003 0.0574 0.0574
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Trypanosoma brucei glucose transporter, putative 0.003 0.0583 0.8491
Trypanosoma brucei THT1 - hexose transporter, putative 0.003 0.0583 0.8491
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0022 0.0375 0.546
Echinococcus granulosus intermediate filament protein 0.0025 0.0458 0.0605
Loa Loa (eye worm) intermediate filament protein 0.0025 0.0458 0.0891
Plasmodium falciparum LCCL domain-containing protein 0.0018 0.0292 0.0292
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0022 0.0375 0.546
Echinococcus granulosus lysyl tRNA synthetase 0.0022 0.0375 0.0495
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.003 0.0574 0.8354
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0177 0.0793
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Plasmodium vivax hexose transporter 0.0097 0.2234 0.2234
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.003 0.0574 0.0869
Trypanosoma brucei glucose transporter, putative 0.003 0.0583 0.8491
Loa Loa (eye worm) hypothetical protein 0.0016 0.0246 0.0479
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0022 0.0384 0.6416
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0022 0.0384 0.5587
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0034 0.0687 0.104
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0344
Echinococcus granulosus solute carrier family 22 0.0014 0.0177 0.0234
Toxoplasma gondii sugar transporter ST1 0.0014 0.0177 0.0268
Brugia malayi intermediate filament protein 0.0025 0.0458 0.0891
Onchocerca volvulus Putative transporter 0.0014 0.0177 0.182
Trypanosoma brucei glucose transporter 2A 0.003 0.0583 0.8491
Onchocerca volvulus 0.0014 0.0177 0.182
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.003 0.0574 0.0757
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0022 0.0384 0.5587
Onchocerca volvulus 0.0018 0.0292 0.3002
Schistosoma mansoni sugar transporter 0.0014 0.0177 0.0793
Brugia malayi hypothetical protein 0.0014 0.0177 0.0344
Trichomonas vaginalis sugar transporter, putative 0.003 0.0583 0.2609
Onchocerca volvulus 0.0014 0.0177 0.182
Loa Loa (eye worm) hypothetical protein 0.0029 0.0559 0.1086
Brugia malayi cytoplasmic intermediate filament protein 0.0013 0.0171 0.0333
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Schistosoma mansoni cellular tumor antigen P53 0.0046 0.0973 0.4356
Echinococcus multilocularis RUN 0.0018 0.0292 0.0385
Onchocerca volvulus 0.0014 0.0177 0.182
Trypanosoma cruzi hexose transporter, putative 0.0016 0.0246 0.3588
Echinococcus multilocularis solute carrier family 22 0.0014 0.0177 0.0234
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0583 0.2609
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0034 0.0687 1
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0022 0.0375 0.1678
Loa Loa (eye worm) hypothetical protein 0.0022 0.0375 0.0729
Echinococcus granulosus solute carrier family 22 0.0014 0.0177 0.0234
Loa Loa (eye worm) sugar transporter 0.0014 0.0177 0.0344
Leishmania major 4-coumarate:coa ligase-like protein 0.0022 0.0384 0.5587
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.003 0.0574 0.0869
Schistosoma mansoni inositol monophosphatase 0.0034 0.0687 0.3073
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.003 0.0574 0.0757
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0029 0.0559 0.1086
Echinococcus multilocularis musashi 0.0025 0.0458 0.0605
Schistosoma mansoni hypothetical protein 0.0018 0.0292 0.1308
Trypanosoma brucei glucose transporter, putative 0.003 0.0583 0.8491
Loa Loa (eye worm) hypothetical protein 0.0022 0.0384 0.0745
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0022 0.0375 0.546
Trypanosoma brucei sugar transporter, putative 0.0014 0.0177 0.258
Onchocerca volvulus 0.0014 0.0177 0.182
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0018 0.0294 0.4923
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Entamoeba histolytica protein kinase, putative 0.003 0.0574 0.8354
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0034 0.0678 0.9871
Mycobacterium ulcerans acyl-CoA synthetase 0.0022 0.0384 0.5587
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0034 0.0687 1
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0097 0.2234 0.2948
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0034 0.0687 0.3073
Echinococcus granulosus lipoxygenase domain containing protein 0.0018 0.0292 0.0385
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0177 0.0344
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0014 0.0177 0.0234
Loa Loa (eye worm) hypothetical protein 0.0016 0.0246 0.0479
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0034 0.0678 0.9871
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0022 0.0384 0.5587
Schistosoma mansoni inositol monophosphatase 0.0034 0.0687 0.3073
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0014 0.0177 0.258
Onchocerca volvulus 0.0014 0.0177 0.182
Leishmania major hypothetical protein, conserved 0.0014 0.0177 0.258
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0022 0.0384 0.5587
Trypanosoma cruzi sugar transporter, putative 0.0014 0.0177 0.258
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0029 0.0559 0.2501
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0014 0.0177 0.2963
Loa Loa (eye worm) hypothetical protein 0.0022 0.0384 0.0745
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0344
Onchocerca volvulus 0.0014 0.0177 0.182
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Brugia malayi Sugar transporter family protein 0.0014 0.0177 0.0344
Plasmodium falciparum calcium-dependent protein kinase 5 0.003 0.0574 0.0574
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0214 0.5145 1
Echinococcus granulosus inositol monophosphatase 1 0.0034 0.0687 0.0906
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0034 0.0678 0.9871
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0022 0.0384 0.6416
Trichomonas vaginalis CAMK family protein kinase 0.003 0.0574 0.2567
Schistosoma mansoni glucose transporter 0.0014 0.0177 0.0793
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Toxoplasma gondii facilitative glucose transporter GT1 0.0097 0.2234 0.3383
Echinococcus multilocularis solute carrier family 22 0.0014 0.0177 0.0234
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0177 0.0793
Loa Loa (eye worm) sugar transporter 0.0097 0.2234 0.4342
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0224 0.3749
Onchocerca volvulus 0.0014 0.0177 0.182
Loa Loa (eye worm) hypothetical protein 0.0022 0.0384 0.0745
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0344
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0012 0.0135 0.0263
Loa Loa (eye worm) hypothetical protein 0.003 0.0574 0.1115
Trichomonas vaginalis sugar transporter, putative 0.003 0.0583 0.2609
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0016 0.0246 0.412
Schistosoma mansoni lysyl-tRNA synthetase 0.0022 0.0375 0.1678
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Loa Loa (eye worm) hypothetical protein 0.0025 0.0458 0.0891
Onchocerca volvulus 0.0014 0.0177 0.182
Toxoplasma gondii transporter, major facilitator family protein 0.0014 0.0177 0.0268
Onchocerca volvulus 0.0018 0.0292 0.3002
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0051 0.1105 0.1458
Leishmania major glucose transporter, lmgt3 0.003 0.0583 0.8491
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0344
Plasmodium falciparum calcium-dependent protein kinase 1 0.003 0.0574 0.0574
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0177 0.0344
Schistosoma mansoni protein kinase 0.003 0.0574 0.2567
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Plasmodium falciparum hexose transporter 0.0097 0.2234 0.2234
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.003 0.0574 0.0757
Treponema pallidum prolyl-tRNA synthetase 0.001 0.0094 0.5
Trypanosoma brucei glucose transporter, putative 0.003 0.0583 0.8491
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.003 0.0574 0.1115
Echinococcus granulosus synaptic vesicle 2 protein 0.0014 0.0177 0.0234
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0031 0.0598 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0051 0.1105 0.1458
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.003 0.0574 0.0757
Schistosoma mansoni protein kinase 0.003 0.0574 0.2567
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.003 0.0574 0.0757
Echinococcus granulosus solute carrier family 22 0.0014 0.0177 0.0234
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0034 0.0678 0.9871
Onchocerca volvulus 0.0014 0.0177 0.182
Onchocerca volvulus 0.0022 0.0384 0.3941
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Schistosoma mansoni protein kinase 0.003 0.0574 0.2567
Plasmodium vivax proline--tRNA ligase, putative 0.0034 0.0678 0.0678
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0156 0.3709 0.3709
Schistosoma mansoni glucose transport protein 0.0097 0.2234 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0344
Onchocerca volvulus 0.0014 0.0177 0.182
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0344
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0034 0.0687 1
Trichomonas vaginalis myo-inositol transporter, putative 0.0014 0.0177 0.0793
Trichomonas vaginalis inositol monophosphatase, putative 0.0034 0.0687 0.3073
Plasmodium falciparum mitogen-activated protein kinase 2 0.0156 0.3709 0.3709
Echinococcus granulosus tumor protein p63 0.0312 0.758 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0034 0.0687 0.3073
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0344
Brugia malayi hypothetical protein 0.0018 0.0292 0.0568
Brugia malayi Doublecortin family protein 0.0018 0.0292 0.0568
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.003 0.0574 0.1115
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0097 0.2234 0.2948
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Trypanosoma brucei THT1 - hexose transporter, putative 0.003 0.0583 0.8491
Mycobacterium ulcerans integral membrane transport protein 0.0014 0.0177 0.258
Loa Loa (eye worm) hypothetical protein 0.0018 0.0292 0.0568
Echinococcus multilocularis solute carrier family 22 0.0014 0.0177 0.0234
Echinococcus granulosus calcium dependent protein kinase 0.0028 0.0528 0.0697
Loa Loa (eye worm) hypothetical protein 0.0046 0.0973 0.1892
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Onchocerca volvulus 0.0014 0.0177 0.182
Schistosoma mansoni lysyl-tRNA synthetase 0.0022 0.0375 0.1678
Giardia lamblia Prolyl-tRNA synthetase 0.0029 0.0559 1
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.003 0.0574 0.0869
Plasmodium vivax acyl-CoA synthetase, putative 0.0016 0.0246 0.0246
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0022 0.0375 0.627
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0025 0.0458 0.0891
Trichomonas vaginalis conserved hypothetical protein 0.0097 0.2234 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0447 0.0869
Loa Loa (eye worm) hypothetical protein 0.0014 0.0177 0.0344
Plasmodium falciparum calcium-dependent protein kinase 3 0.003 0.0574 0.0574
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0031 0.0598 1
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0177 0.0344
Trypanosoma brucei glucose transporter, putative 0.003 0.0583 0.8491
Schistosoma mansoni glucose transport protein 0.0097 0.2234 1
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.003 0.0574 0.0757
Trichomonas vaginalis glucose transporter, putative 0.003 0.0583 0.2609
Loa Loa (eye worm) hypothetical protein 0.0024 0.0424 0.0824
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0016 0.0246 0.542
Loa Loa (eye worm) hypothetical protein 0.0016 0.0246 0.0479
Echinococcus multilocularis lamin 0.0025 0.0458 0.0605
Echinococcus granulosus RUN 0.0018 0.0292 0.0385
Trichomonas vaginalis sugar transporter, putative 0.0014 0.0177 0.0793
Trypanosoma brucei glucose transporter, putative 0.003 0.0583 0.8491

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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