Detailed information for compound 876133

Basic information

Technical information
  • TDR Targets ID: 876133
  • Name: N-(4-fluorophenyl)-2-[(2-fluorophenyl)methyls ulfanyl]acetamide
  • MW: 293.332 | Formula: C15H13F2NOS
  • H donors: 1 H acceptors: 1 LogP: 3.47 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ccc(cc1)F)CSCc1ccccc1F
  • InChi: 1S/C15H13F2NOS/c16-12-5-7-13(8-6-12)18-15(19)10-20-9-11-3-1-2-4-14(11)17/h1-8H,9-10H2,(H,18,19)
  • InChiKey: SQQRGYPSAXROQG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(4-fluorophenyl)-2-[(2-fluorophenyl)methylthio]acetamide
  • 2-[(2-fluorobenzyl)thio]-N-(4-fluorophenyl)acetamide
  • N-(4-fluorophenyl)-2-[(2-fluorophenyl)methylsulfanyl]ethanamide
  • ZINC00148692

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0023 0.0161 0.0399
Brugia malayi polk-prov protein 0.0042 0.054 0.0798
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0324 0.6176 0.9283
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Trypanosoma brucei glucose transporter, putative 0.0038 0.0454 0.3759
Brugia malayi larval opioid receptor 0.0016 0.0026 0.0023
Plasmodium falciparum basic transcription factor 3b, putative 0.0072 0.1137 0.1099
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0196 0.3622 0.3595
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0027 0.0249 0.1889
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0042 0.055 0.4636
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.034 0.6487 1
Echinococcus granulosus solute carrier family 22 0.0017 0.0042 0.0048
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0036 0.0416 0.061
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0016 0.0026 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.054 0.4551
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Echinococcus granulosus tachykinin peptides receptor 99D 0.0016 0.0026 0.0023
Echinococcus multilocularis G protein coupled receptor 139 0.0016 0.0026 0.0023
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0047 0.0648 0.0608
Trypanosoma cruzi hexose transporter, putative 0.0038 0.0454 0.3759
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0027 0.0243 0.0674
Brugia malayi Dopamine receptor protein 2 0.0016 0.0026 0.0023
Echinococcus granulosus neuropeptide FF receptor 2 0.0016 0.0026 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0026 0.0023
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0016 0.0026 0.0023
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0025 0.0203 0.0289
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0026 0.0023
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0064
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0348 0.6653 0.9991
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0016 0.0026 0.0023
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0121 0.2128 0.3184
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Echinococcus granulosus calcium dependent protein kinase 0.0035 0.0398 0.0583
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0016 0.0026 0.0039
Trichomonas vaginalis CAMK family protein kinase 0.0037 0.0444 0.0623
Brugia malayi Sugar transporter family protein 0.0017 0.0042 0.0048
Echinococcus granulosus somatostatin receptor 0.0016 0.0026 0.0023
Echinococcus granulosus dro:myosuppressin receptor 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0036 0.0416 0.0625
Schistosoma mansoni biogenic amine receptor 0.0016 0.0026 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0026 0.0023
Echinococcus granulosus tm gpcr rhodopsin 0.0016 0.0026 0.0023
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.034 0.6487 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0027 0.0249 0.1889
Plasmodium falciparum proline--tRNA ligase 0.0042 0.055 0.051
Onchocerca volvulus 0.0017 0.0042 0.0146
Mycobacterium ulcerans putative regulatory protein 0.0071 0.113 0.3656
Trichomonas vaginalis conserved hypothetical protein 0.0121 0.2128 0.3236
Schistosoma mansoni amine GPCR 0.0016 0.0026 0.0023
Echinococcus granulosus g protein coupled receptor 0.0016 0.0026 0.0023
Mycobacterium ulcerans DNA polymerase IV 0.0067 0.1033 0.3332
Onchocerca volvulus Putative transporter 0.0017 0.0042 0.0146
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0016 0.0026 0.0023
Brugia malayi hypothetical protein 0.0016 0.0026 0.0023
Schistosoma mansoni flap endonuclease-1 0.0027 0.0248 0.0357
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0037 0.0445 0.0617
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0016 0.0026 0.0023
Schistosoma mansoni amine GPCR 0.0016 0.0026 0.0023
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0121 0.2128 0.3184
Leishmania major lysyl-tRNA synthetase, putative 0.0027 0.0243 0.1831
Schistosoma mansoni opsin-like receptor 0.0016 0.0026 0.0023
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0045 0.0596 0.088
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0064
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0045 0.0596 0.0556
Trypanosoma cruzi hexose transporter, putative 0.0021 0.0113 0.0641
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0016 0.0026 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.1033 0.9054
Brugia malayi Dopamine receptor 0.0016 0.0026 0.0023
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0016 0.0026 0.0023
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0016 0.0026 0.0023
Loa Loa (eye worm) sugar transporter 0.0017 0.0042 0.0064
Giardia lamblia Flap structure-specific endonuclease 0.003 0.0306 0.0409
Leishmania major protein kinase, putative 0.0037 0.0444 0.3672
Schistosoma mansoni glucose transporter 0.0017 0.0042 0.0048
Plasmodium falciparum protein kinase 7 0.0343 0.6557 0.6542
Echinococcus multilocularis General substrate transporter 0.0104 0.1787 0.2671
Schistosoma mansoni sugar transporter 0.0017 0.0042 0.0048
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0036 0.0429 0.0645
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0037 0.0444 0.0653
Plasmodium falciparum mitogen-activated protein kinase 2 0.0196 0.3622 0.3595
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0016 0.0026 0.0023
Schistosoma mansoni terminal deoxycytidyl transferase 0.0036 0.0416 0.061
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0016 0.0026 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0203 0.0249
Schistosoma mansoni histamine h1 receptor 0.0016 0.0026 0.0023
Trypanosoma cruzi transcription factor btf3, putative 0.0072 0.1137 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.1033 0.9054
Echinococcus granulosus General substrate transporter 0.0104 0.1787 0.2671
Echinococcus multilocularis solute carrier family 22 0.0017 0.0042 0.0048
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0026 0.0023
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0016 0.0026 0.0023
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0036 0.0416 0.061
Trypanosoma cruzi hexose transporter, putative 0.0038 0.0454 0.3759
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0203 0.0249
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0203 0.0249
Onchocerca volvulus 0.0017 0.0042 0.0146
Echinococcus multilocularis serotonin receptor 0.0016 0.0026 0.0023
Echinococcus multilocularis geminin 0.0348 0.6659 1
Leishmania major DNA polymerase eta, putative 0.0036 0.0416 0.3413
Brugia malayi sulfakinin receptor protein 0.0016 0.0026 0.0023
Trypanosoma brucei glucose transporter, putative 0.0038 0.0454 0.3759
Echinococcus granulosus g-protein coupled receptor 0.0016 0.0026 0.0023
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0037 0.0445 0.0404
Echinococcus multilocularis neuropeptide Y receptor 0.0016 0.0026 0.0023
Onchocerca volvulus 0.0017 0.0042 0.0146
Brugia malayi hypothetical protein 0.0017 0.0042 0.0048
Loa Loa (eye worm) hypoxia-induced factor 1 0.0299 0.5674 0.8529
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0045 0.0596 0.088
Schistosoma mansoni lysyl-tRNA synthetase 0.0027 0.0243 0.0349
Brugia malayi hypoxia-induced factor 1 0.0299 0.5674 0.8526
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Loa Loa (eye worm) hypothetical protein 0.0037 0.0444 0.0668
Echinococcus multilocularis dna polymerase kappa 0.0067 0.1033 0.1538
Plasmodium vivax basic transcription factor 3b, putative 0.0072 0.1137 0.1099
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Loa Loa (eye worm) hypothetical protein 0.0036 0.0429 0.0645
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0016 0.0026 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.1033 0.9054
Onchocerca volvulus 0.0071 0.113 1
Echinococcus granulosus tm gpcr rhodopsin 0.0016 0.0026 0.0023
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0016 0.0026 0.0023
Schistosoma mansoni neuropeptide receptor 0.0016 0.0026 0.0023
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0016 0.0026 0.0023
Brugia malayi putative neuropeptide receptor NPR1 0.0016 0.0026 0.0023
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0037 0.0444 0.0652
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0026 0.0023
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0045 0.0596 0.085
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Brugia malayi G protein-coupled receptor F59B2.13 0.0016 0.0026 0.0023
Trypanosoma brucei DNA polymerase IV, putative 0.0059 0.088 0.7655
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0069 0.1086 0.1048
Echinococcus multilocularis solute carrier family 22 0.0017 0.0042 0.0048
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0025 0.0203 0.0249
Echinococcus granulosus serotonin receptor 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0064
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0017 0.0042 0.0048
Echinococcus multilocularis neuropeptide FF receptor 2 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0064
Schistosoma mansoni protein kinase 0.0037 0.0444 0.0652
Entamoeba histolytica recQ family helicase, putative 0.0051 0.0724 0.092
Schistosoma mansoni aryl hydrocarbon receptor 0.0097 0.1631 0.2437
Brugia malayi hypothetical protein 0.0016 0.0026 0.0023
Schistosoma mansoni lysyl-tRNA synthetase 0.0027 0.0243 0.0349
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0203 0.0249
Plasmodium falciparum hexose transporter 0.0121 0.2128 0.2094
Brugia malayi major facilitator superfamily protein 0.0017 0.0042 0.0048
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.003 0.0306 0.2407
Entamoeba histolytica protein kinase, putative 0.0037 0.0444 0.0479
Toxoplasma gondii facilitative glucose transporter GT1 0.0121 0.2128 0.3201
Echinococcus granulosus flap endonuclease 1 0.003 0.0306 0.0444
Plasmodium vivax calcium-dependent protein kinase, putative 0.0037 0.0445 0.0404
Onchocerca volvulus 0.0017 0.0042 0.0146
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0121 0.2128 0.3184
Echinococcus granulosus geminin 0.0348 0.6659 1
Schistosoma mansoni hypothetical protein 0.0348 0.6659 1
Echinococcus multilocularis fmrfamide receptor 0.0016 0.0026 0.0023
Schistosoma mansoni glucose transport protein 0.0121 0.2128 0.3184
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.2043 0.3071
Echinococcus granulosus sex peptide receptor 0.0016 0.0026 0.0023
Trichomonas vaginalis DNA helicase recq, putative 0.0076 0.1214 0.1818
Trypanosoma brucei DNA polymerase IV, putative 0.0067 0.1033 0.9054
Schistosoma mansoni myosin xvIII 0.0016 0.0026 0.0023
Schistosoma mansoni neuropeptide receptor 0.0016 0.0026 0.0023
Schistosoma mansoni amine GPCR 0.0016 0.0026 0.0023
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0157 0.0176
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0045 0.0596 0.0881
Brugia malayi GnHR receptor homolog 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0026 0.0023
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0016 0.0026 0.0023
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0036 0.0429 0.063
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0037 0.0444 0.0652
Echinococcus granulosus transcription factor btf3 0.0072 0.1137 0.1694
Schistosoma mansoni hypothetical protein 0.0016 0.0026 0.0023
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0045 0.0596 0.0896
Echinococcus multilocularis serotonin receptor 0.0016 0.0026 0.0023
Trypanosoma brucei glucose transporter 2A 0.0038 0.0454 0.3759
Trypanosoma brucei transcription factor BTF3, putative 0.0072 0.1137 1
Loa Loa (eye worm) TYRA-2 protein 0.0016 0.0026 0.0039
Echinococcus multilocularis G-protein coupled receptor, putative 0.0016 0.0026 0.0023
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0016 0.0026 0.0039
Schistosoma mansoni biogenic amine receptor 0.0016 0.0026 0.0023
Echinococcus multilocularis transcription factor btf3 0.0072 0.1137 0.1694
Brugia malayi putative neuropeptide receptor 0.0016 0.0026 0.0023
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0037 0.0445 0.0617
Giardia lamblia Prolyl-tRNA synthetase 0.0036 0.0429 0.06
Trypanosoma brucei DNA polymerase kappa, putative 0.0042 0.054 0.4551
Echinococcus granulosus fmrfamide receptor 0.0016 0.0026 0.0023
Echinococcus multilocularis calcium dependent protein kinase 0.0035 0.0398 0.0583
Schistosoma mansoni glucose transport protein 0.0121 0.2128 0.3184
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0348 0.6653 0.9991
Onchocerca volvulus 0.0017 0.0042 0.0146
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0026 0.0023
Loa Loa (eye worm) major facilitator superfamily transporter 0.0017 0.0042 0.0064
Schistosoma mansoni neuropeptide receptor 0.0016 0.0026 0.0023
Schistosoma mansoni blooms syndrome DNA helicase 0.0023 0.0157 0.0221
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0025 0.0203 0.0305
Echinococcus granulosus neuropeptide Y receptor 0.0016 0.0026 0.0023
Echinococcus granulosus neuropeptides capa receptor 0.0016 0.0026 0.0023
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0203 0.1465
Echinococcus multilocularis aryl hydrocarbon receptor 0.0025 0.0203 0.0289
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0051 0.0724 0.6226
Trypanosoma brucei glucose transporter, putative 0.0038 0.0454 0.3759
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0121 0.2128 0.3184
Trypanosoma brucei glucose transporter, putative 0.0038 0.0454 0.3759
Giardia lamblia Lysyl-tRNA synthetase 0.0027 0.0243 0.0311
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0016 0.0026 0.0023
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0036 0.0429 0.063
Loa Loa (eye worm) hypothetical protein 0.0172 0.3137 0.4715
Leishmania major DNA polymerase kappa, putative 0.0043 0.0569 0.4812
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0017 0.0042 0.5
Brugia malayi ImpB/MucB/SamB family protein 0.0036 0.0416 0.061
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.034 0.6487 1
Entamoeba histolytica recQ family DNA helicase 0.0023 0.0157 0.0027
Toxoplasma gondii NAC domain-containing protein 0.0072 0.1137 0.168
Echinococcus granulosus single minded 2 0.0071 0.113 0.1683
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0064
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0011 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.1033 0.9054
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0064
Echinococcus granulosus hypothetical protein 0.0016 0.0026 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.1033 0.9054
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0051 0.0724 0.6226
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0196 0.3622 0.5495
Loa Loa (eye worm) RecQ helicase 0.0076 0.1214 0.1825
Trypanosoma brucei unspecified product 0.0025 0.0194 0.1386
Echinococcus multilocularis neuropeptide receptor 0.0016 0.0026 0.0023
Echinococcus multilocularis sex peptide receptor 0.0016 0.0026 0.0023
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0203 0.1465
Schistosoma mansoni biogenic amine (5HT) receptor 0.0016 0.0026 0.0023
Giardia lamblia Sgs1 DNA helicase, putative 0.0045 0.0596 0.0859
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0046 0.063 0.0902
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0019 0.0076 0.0052
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0166 0.3016 1
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.037 0.0541
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0157 0.105
Entamoeba histolytica protein kinase, putative 0.0037 0.0444 0.0479
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0121 0.2128 0.3184
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0036 0.0429 0.063
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0051 0.0724 0.6226
Leishmania major basic transcription factor 3a, putative 0.0072 0.1137 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0016 0.0026 0.0023
Entamoeba histolytica Flap nuclease, putative 0.003 0.0306 0.0261
Trichomonas vaginalis sugar transporter, putative 0.0038 0.0454 0.0638
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0064
Trypanosoma cruzi hexose transporter, putative 0.0038 0.0454 0.3759
Brugia malayi beta-NAC-like protein 0.0072 0.1137 0.1695
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0036 0.0416 0.061
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.034 0.6487 1
Echinococcus granulosus Sugar transporter ERD6 protein 0.0017 0.0042 0.0048
Schistosoma mansoni glucose transport protein 0.0121 0.2128 0.3184
Brugia malayi MH2 domain containing protein 0.0117 0.2043 0.306
Schistosoma mansoni DNA polymerase eta 0.0036 0.0416 0.061
Trypanosoma brucei glucose transporter, putative 0.0038 0.0454 0.3759
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Brugia malayi lysyl-tRNA synthetase 0.0027 0.0243 0.035
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0016 0.0026 0.0023
Brugia malayi RE15519p 0.0016 0.0026 0.0023
Brugia malayi Dopamine receptor protein 1 0.0016 0.0026 0.0023
Trypanosoma brucei THT1 - hexose transporter, putative 0.0038 0.0454 0.3759
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0027 0.0249 0.1889
Schistosoma mansoni alpha-1 adrenergic receptor 0.0016 0.0026 0.0023
Loa Loa (eye worm) sugar transporter 0.0121 0.2128 0.3198
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.003 0.0306 0.2407
Echinococcus granulosus neuropeptide s receptor 0.0016 0.0026 0.0023
Brugia malayi hypothetical protein 0.0016 0.0026 0.0023
Brugia malayi Major Facilitator Superfamily protein 0.0017 0.0042 0.0048
Trypanosoma brucei unspecified product 0.0025 0.0194 0.1386
Schistosoma mansoni hypothetical protein 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0203 0.0249
Echinococcus granulosus neuropeptide Y receptor 0.0016 0.0026 0.0023
Schistosoma mansoni hypothetical protein 0.0033 0.037 0.054
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0036 0.0429 0.063
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0026 0.0023
Schistosoma mansoni hypothetical protein 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Brugia malayi hypothetical protein 0.0016 0.0026 0.0023
Trypanosoma brucei glucose transporter, putative 0.0038 0.0454 0.3759
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.1033 0.9054
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0027 0.0243 0.0286
Schistosoma mansoni amine GPCR 0.0016 0.0026 0.0023
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0037 0.0444 0.0652
Schistosoma mansoni biogenic amine receptor 0.0016 0.0026 0.0023
Trypanosoma brucei glucose transporter 1E 0.0038 0.0454 0.3759
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Schistosoma mansoni neuropeptide f receptor 76f 0.0016 0.0026 0.0023
Trypanosoma cruzi transcription factor btf3, putative 0.0072 0.1137 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.034 0.6487 1
Echinococcus multilocularis neuropeptides capa receptor 0.0016 0.0026 0.0023
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0025 0.0203 0.0289
Echinococcus multilocularis bloom syndrome protein 0.0076 0.1214 0.181
Loa Loa (eye worm) flap endonuclease-1 0.003 0.0306 0.046
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0042 0.055 0.4636
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0024 0.0176 0.0207
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0347 0.2786
Trichomonas vaginalis sugar transporter, putative 0.0038 0.0454 0.0638
Brugia malayi hypothetical protein 0.0016 0.0026 0.0023
Plasmodium falciparum calcium-dependent protein kinase 5 0.0037 0.0445 0.0404
Echinococcus granulosus g protein coupled receptor 0.0016 0.0026 0.0023
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0016 0.0026 0.0023
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0037 0.0444 0.0652
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0067 0.1033 0.1537
Plasmodium falciparum flap endonuclease 1 0.003 0.0306 0.0265
Trichomonas vaginalis glucose transporter, putative 0.0038 0.0454 0.0638
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0348 0.6653 0.9991
Echinococcus granulosus aryl hydrocarbon receptor 0.0025 0.0203 0.0289
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0348 0.6653 1
Trypanosoma brucei DNA polymerase IV, putative 0.0067 0.1033 0.9054
Schistosoma mansoni protein kinase 0.0037 0.0444 0.0652
Brugia malayi follicle stimulating hormone receptor 0.0016 0.0026 0.0023
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0017 0.0042 0.0048
Echinococcus multilocularis solute carrier family 22 0.0017 0.0042 0.0048
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0037 0.0445 0.0404
Brugia malayi hypothetical protein 0.0017 0.0042 0.0048
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0026 0.0023
Brugia malayi AKH receptor 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0025 0.0203 0.0305
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0045 0.0596 0.0896
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0203 0.0249
Echinococcus granulosus solute carrier family 22 0.0017 0.0042 0.0048
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0037 0.0445 0.0404
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0064
Echinococcus granulosus 7TM GPCR rhodopsin 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0064
Entamoeba histolytica hypothetical protein 0.0072 0.1137 0.1571
Echinococcus multilocularis neuropeptide receptor 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Brugia malayi ORL1-like opioid receptor 0.0016 0.0026 0.0023
Onchocerca volvulus 0.0017 0.0042 0.0146
Onchocerca volvulus 0.0017 0.0042 0.0146
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.1137 0.1698
Echinococcus multilocularis allatostatin A receptor 0.0016 0.0026 0.0023
Echinococcus granulosus peptide allatostatin:somatostatin 0.0016 0.0026 0.0023
Loa Loa (eye worm) G-protein coupled receptor 0.0016 0.0026 0.0039
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0042 0.055 0.0779
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Schistosoma mansoni neuropeptide F-like receptor 0.0016 0.0026 0.0023
Echinococcus multilocularis neuropeptide receptor A26 0.0016 0.0026 0.0023
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0027 0.0243 0.0311
Plasmodium vivax lysine--tRNA ligase, putative 0.0027 0.0243 0.0201
Schistosoma mansoni neuropeptide F-like receptor 0.0016 0.0026 0.0023
Entamoeba histolytica transcription factor BTF3, putative 0.0072 0.1137 0.1571
Brugia malayi neuropeptide F receptor 0.0016 0.0026 0.0023
Onchocerca volvulus 0.0017 0.0042 0.0146
Echinococcus granulosus g protein coupled receptor 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0064
Schistosoma mansoni hypothetical protein 0.0348 0.6659 1
Plasmodium falciparum calcium-dependent protein kinase 3 0.0037 0.0445 0.0404
Brugia malayi Melatonin receptor type 1A 0.0016 0.0026 0.0023
Schistosoma mansoni hypothetical protein 0.0121 0.2128 0.3184
Schistosoma mansoni DNA helicase recq5 0.0045 0.0596 0.088
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0026 0.0023
Brugia malayi G protein-coupled receptor 0.0016 0.0026 0.0023
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.003 0.0306 0.0404
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.1137 0.1698
Schistosoma mansoni sugar transporter 0.0017 0.0042 0.0048
Trichomonas vaginalis sugar transporter, putative 0.0038 0.0454 0.0638
Schistosoma mansoni adenoreceptor 0.0016 0.0026 0.0023
Echinococcus granulosus orexin receptor type 2 0.0016 0.0026 0.0023
Onchocerca volvulus 0.0017 0.0042 0.0146
Echinococcus granulosus alpha 1A adrenergic receptor 0.0016 0.0026 0.0023
Trichomonas vaginalis flap endonuclease-1, putative 0.003 0.0306 0.0409
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0166 0.3016 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Echinococcus multilocularis solute carrier family 22 0.0017 0.0042 0.0048
Trypanosoma cruzi hexose transporter 0.0038 0.0454 0.3759
Trypanosoma brucei THT1 - hexose transporter, putative 0.0038 0.0454 0.3759
Brugia malayi PAS domain containing protein 0.0097 0.1631 0.244
Brugia malayi Sugar transporter family protein 0.0121 0.2128 0.3187
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Loa Loa (eye worm) hypothetical protein 0.0049 0.0679 0.1021
Schistosoma mansoni biogenic amine (5HT) receptor 0.0016 0.0026 0.0023
Schistosoma mansoni DNA helicase recq1 0.0045 0.0596 0.088
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0016 0.0026 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0026 0.0023
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0016 0.0026 0.0023
Leishmania major flap endonuclease-1 (FEN-1), putative 0.003 0.0306 0.2407
Brugia malayi major facilitator superfamily protein 0.0017 0.0042 0.0048
Mycobacterium tuberculosis Conserved hypothetical protein 0.0036 0.0416 0.1256
Echinococcus granulosus biogenic amine 5HT receptor 0.0016 0.0026 0.0023
Brugia malayi ImpB/MucB/SamB family protein 0.0036 0.0416 0.061
Loa Loa (eye worm) major facilitator superfamily transporter 0.0017 0.0042 0.0064
Brugia malayi hypothetical protein 0.0324 0.6176 0.9282
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0037 0.0444 0.3672
Echinococcus multilocularis neuropeptides capa receptor 0.0016 0.0026 0.0023
Plasmodium vivax CDK-related protein kinase 6, putative 0.0515 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0026 0.0023
Leishmania major glucose transporter, lmgt1 0.0038 0.0454 0.3759
Loa Loa (eye worm) hypothetical protein 0.0027 0.0243 0.0365
Toxoplasma gondii protein kinase, putative 0.0343 0.6557 1
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0036 0.0429 0.0456
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0026 0.0023
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0036 0.0416 0.0625
Schistosoma mansoni neuropeptide receptor 0.0016 0.0026 0.0023
Brugia malayi G-protein coupled receptor 0.0016 0.0026 0.0023
Trypanosoma brucei glucose transporter, putative 0.0038 0.0454 0.3759
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0203 0.0249
Schistosoma mansoni opsin-like receptor 0.0016 0.0026 0.0023
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.034 0.6487 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0064
Echinococcus granulosus lysyl tRNA synthetase 0.0027 0.0243 0.0349
Schistosoma mansoni transcription factor btf3 0.0072 0.1137 0.1694
Echinococcus multilocularis fmrfamide receptor 0.0016 0.0026 0.0023
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0043 0.0569 0.4812
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Trypanosoma brucei THT1 - hexose transporter, putative 0.0038 0.0454 0.3759
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0203 0.1465
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Trypanosoma cruzi DNA polymerase eta, putative 0.0036 0.0416 0.3413
Onchocerca volvulus 0.0017 0.0042 0.0146
Trypanosoma brucei DNA polymerase eta, putative 0.0036 0.0416 0.3413
Loa Loa (eye worm) neuropeptide F receptor 0.0016 0.0026 0.0039
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0037 0.0445 0.0617
Echinococcus granulosus synaptic vesicle 2 protein 0.0017 0.0042 0.0048
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0037 0.0444 0.0668
Trichomonas vaginalis glucose transporter, putative 0.0038 0.0454 0.0638
Echinococcus granulosus biogenic amine 5HT receptor 0.0016 0.0026 0.0023
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0027 0.0243 0.0674
Plasmodium falciparum lysine--tRNA ligase 0.0027 0.0243 0.0201
Trypanosoma brucei glucose transporter, putative 0.0038 0.0454 0.3759
Schistosoma mansoni opsin-like receptor 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Brugia malayi bHLH-PAS transcription factor 0.0071 0.113 0.1684
Plasmodium falciparum calcium-dependent protein kinase 4 0.0037 0.0445 0.0404
Mycobacterium ulcerans DNA polymerase IV 0.0067 0.1033 0.3332
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0454 0.0638
Echinococcus multilocularis dna polymerase eta 0.0036 0.0416 0.061
Echinococcus multilocularis orexin receptor type 2 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0072 0.1137 0.1698
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0043 0.0569 0.1771
Echinococcus multilocularis somatostatin receptor 0.0016 0.0026 0.0023
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0023 0.0161 0.0399
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0036 0.0429 0.063
Loa Loa (eye worm) hypothetical protein 0.0042 0.054 0.0812
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0037 0.0444 0.0652
Echinococcus granulosus solute carrier family 22 0.0017 0.0042 0.0048
Echinococcus granulosus neuropeptide receptor 0.0016 0.0026 0.0023
Schistosoma mansoni protein kinase 0.0037 0.0444 0.0652
Echinococcus granulosus tm gpcr rhodopsin 0.0016 0.0026 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0454 0.0638
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0121 0.2128 0.3184
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0064
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.034 0.6487 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0348 0.6653 1
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0121 0.2128 0.3184
Brugia malayi Bloom's syndrome protein homolog 0.0076 0.1214 0.1812
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0203 0.0249
Mycobacterium leprae Possible regulatory protein 0.0025 0.0203 0.0146
Echinococcus multilocularis neuropeptide Y receptor 0.0016 0.0026 0.0023
Plasmodium falciparum calcium-dependent protein kinase 1 0.0037 0.0445 0.0404
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0064
Echinococcus multilocularis g protein coupled receptor 0.0016 0.0026 0.0023
Echinococcus multilocularis dro:myosuppressin receptor 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0033 0.037 0.0556
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0064
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0026 0.0023
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.034 0.6487 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Leishmania major glucose transporter/membrane transporter D2, putative 0.0038 0.0454 0.3759
Brugia malayi Flap endonuclease-1 0.003 0.0306 0.0444
Loa Loa (eye worm) hypothetical protein 0.0015 0.0011 0.0016
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0166 0.3016 1
Schistosoma mansoni sugar transporter 0.0017 0.0042 0.0048
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0016 0.0026 0.0039
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0026 0.0023
Echinococcus multilocularis lysyl tRNA synthetase 0.0027 0.0243 0.0349
Echinococcus granulosus dna polymerase eta 0.0036 0.0416 0.061
Treponema pallidum fructose-bisphosphate aldolase 0.034 0.6487 1
Giardia lamblia DINP protein human, muc B family 0.0043 0.0569 0.0817
Brugia malayi Major Facilitator Superfamily protein 0.0017 0.0042 0.0048
Trichomonas vaginalis DNA helicase recq1, putative 0.0076 0.1214 0.1818
Schistosoma mansoni sugar transporter 0.0017 0.0042 0.0048
Brugia malayi Serotonin receptor 0.0016 0.0026 0.0023
Brugia malayi hypothetical protein 0.0016 0.0026 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.1033 0.9054
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0347 0.2786
Onchocerca volvulus 0.0017 0.0042 0.0146
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0026 0.0023
Echinococcus granulosus bloom syndrome protein 0.0076 0.1214 0.181
Giardia lamblia Fructose-bisphosphate aldolase 0.034 0.6487 1
Brugia malayi hypothetical protein 0.0016 0.0026 0.0023
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0023 0.0157 0.105
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0027 0.0243 0.1831
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Plasmodium vivax proline--tRNA ligase, putative 0.0042 0.055 0.051
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0036 0.0429 0.0939
Loa Loa (eye worm) melatonin receptor type 1A 0.0016 0.0026 0.0039
Trichomonas vaginalis DNA helicase recq, putative 0.0051 0.0724 0.1057
Echinococcus multilocularis neuropeptide s receptor 0.0016 0.0026 0.0023
Leishmania major glucose transporter, lmgt3 0.0038 0.0454 0.3759
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0016 0.0026 0.0023
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0027 0.0243 0.1831
Trypanosoma cruzi DNA polymerase kappa, putative 0.0067 0.1033 0.9054
Brugia malayi Serotonin receptor 0.0016 0.0026 0.0023
Plasmodium vivax flap endonuclease 1, putative 0.003 0.0306 0.0265
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.034 0.6487 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.034 0.6487 1
Chlamydia trachomatis lysine--tRNA ligase 0.0027 0.0243 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0016 0.0026 0.0023
Trypanosoma cruzi DNA polymerase kappa, putative 0.0067 0.1033 0.9054
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0679 0.1007
Loa Loa (eye worm) hypothetical protein 0.0017 0.0042 0.0064
Brugia malayi hypothetical protein 0.0017 0.0042 0.0048
Echinococcus granulosus neuropeptide receptor 0.0016 0.0026 0.0023
Onchocerca volvulus 0.0017 0.0042 0.0146
Onchocerca volvulus 0.0017 0.0042 0.0146
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0037 0.0444 0.0652
Leishmania major protein kinase, putative 0.0027 0.0249 0.1889
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0016 0.0026 0.0023
Leishmania major glucose transporter, lmgt2 0.0038 0.0454 0.3759
Echinococcus multilocularis synaptic vesicle 2 protein 0.0017 0.0042 0.0048
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Onchocerca volvulus 0.0017 0.0042 0.0146
Brugia malayi hypothetical protein 0.0016 0.0026 0.0023
Echinococcus granulosus dna polymerase kappa 0.0067 0.1033 0.1538
Loa Loa (eye worm) G-protein coupled receptor 0.0016 0.0026 0.0039
Trypanosoma cruzi DNA polymerase kappa, putative 0.0067 0.1033 0.9054
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0016 0.0026 0.0023
Echinococcus granulosus allatostatin A receptor 0.0016 0.0026 0.0023
Trichomonas vaginalis DNA polymerase eta, putative 0.0067 0.1033 0.1537
Loa Loa (eye worm) ICD-1 protein 0.0072 0.1137 0.1709
Brugia malayi neuropeptide F receptor 0.0016 0.0026 0.0023
Brugia malayi Major Facilitator Superfamily protein 0.0017 0.0042 0.0048
Entamoeba histolytica hypothetical protein 0.0027 0.0243 0.0162
Leishmania major protein kinase, putative 0.0027 0.0249 0.1889
Echinococcus granulosus neuropeptides capa receptor 0.0016 0.0026 0.0023
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0016 0.0026 0.0023
Echinococcus granulosus G protein coupled receptor 139 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.003 0.0293 0.044
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0036 0.0429 0.06
Brugia malayi hypothetical protein 0.0016 0.0026 0.0023
Schistosoma mansoni serine/threonine protein kinase 0.0037 0.0444 0.0652
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0679 0.1021
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0027 0.0249 0.1889
Schistosoma mansoni growth hormone secretagogue receptor 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Onchocerca volvulus 0.0017 0.0042 0.0146
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0016 0.0026 0.0039
Schistosoma mansoni single-minded 0.0097 0.1631 0.2437
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0037 0.0444 0.0668
Brugia malayi Cam kinase protein 1 0.0037 0.0444 0.0653
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0026 0.0023
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0045 0.0596 0.085
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0042 0.055 0.4636
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0121 0.2128 0.3184
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0016 0.0026 0.0039
Plasmodium falciparum calcium-dependent protein kinase 2 0.0037 0.0445 0.0404
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.2043 0.3071
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0025 0.0203 0.0249
Schistosoma mansoni blooms syndrome DNA helicase 0.0053 0.0758 0.1124
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0026 0.0023
Echinococcus granulosus rhodopsin orphan GPCR 0.0016 0.0026 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Loa Loa (eye worm) neuropeptide F receptor 0.0016 0.0026 0.0039
Toxoplasma gondii lysine-tRNA ligase 0.0027 0.0243 0.0308
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0203 0.0249
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0037 0.0444 0.0652
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0045 0.0596 0.088
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.0347 0.2786
Schistosoma mansoni hypothetical protein 0.0016 0.0026 0.0023
Echinococcus multilocularis flap endonuclease 1 0.003 0.0306 0.0444
Brugia malayi Sugar transporter family protein 0.0017 0.0042 0.0048
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Loa Loa (eye worm) hypothetical protein 0.0023 0.0157 0.0236
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0016 0.0026 0.0023
Echinococcus multilocularis rhodopsin orphan GPCR 0.0016 0.0026 0.0023
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0045 0.0596 0.088
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0679 0.1007
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0045 0.0596 0.0881
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.1033 0.9054
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.0569 0.4812
Trypanosoma brucei unspecified product 0.0059 0.088 0.7655
Schistosoma mansoni amine GPCR 0.0016 0.0026 0.0023
Trypanosoma cruzi DNA polymerase kappa, putative 0.0067 0.1033 0.9054
Echinococcus granulosus 7tm_1 domain containing protein 0.0016 0.0026 0.0023
Echinococcus multilocularis g-protein coupled receptor 0.0016 0.0026 0.0023
Echinococcus granulosus neuropeptide receptor A26 0.0016 0.0026 0.0023
Onchocerca volvulus 0.0017 0.0042 0.0146
Trypanosoma brucei DNA polymerase kappa, putative 0.0067 0.1033 0.9054
Onchocerca volvulus 0.0025 0.0203 0.16
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0037 0.0444 0.0652
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Echinococcus multilocularis g protein coupled receptor 0.0016 0.0026 0.0023
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0036 0.0429 0.063
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0042 0.055 0.4636
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0042 0.055 0.4636
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0016 0.0026 0.0023
Entamoeba histolytica deoxycytidyl transferase, putative 0.0036 0.0416 0.0435
Echinococcus multilocularis transfer RNA-Lys 0.0071 0.113 0.1683
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Brugia malayi hypothetical protein 0.0016 0.0026 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0026 0.0023
Echinococcus multilocularis g protein coupled receptor 0.0016 0.0026 0.0023
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0022 0.014 0.0098
Plasmodium vivax hexose transporter 0.0121 0.2128 0.2094
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0016 0.0026 0.0023
Echinococcus granulosus solute carrier family 22 0.0017 0.0042 0.0048
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Loa Loa (eye worm) hypothetical protein 0.0016 0.0026 0.0039
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0016 0.0026 0.0023
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0016 0.0026 0.0023
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0016 0.0026 0.0023
Brugia malayi G-protein coupled receptor 0.0016 0.0026 0.0023

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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