Detailed information for compound 909554

Basic information

Technical information
  • TDR Targets ID: 909554
  • Name: N-[4-[[4-(benzoylamino)-3-chlorophenyl]methyl ]-2-chlorophenyl]benzamide
  • MW: 475.366 | Formula: C27H20Cl2N2O2
  • H donors: 2 H acceptors: 2 LogP: 6.77 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1cc(ccc1NC(=O)c1ccccc1)Cc1ccc(c(c1)Cl)NC(=O)c1ccccc1
  • InChi: 1S/C27H20Cl2N2O2/c28-22-16-18(11-13-24(22)30-26(32)20-7-3-1-4-8-20)15-19-12-14-25(23(29)17-19)31-27(33)21-9-5-2-6-10-21/h1-14,16-17H,15H2,(H,30,32)(H,31,33)
  • InChiKey: QJNLKJPKXYNKPM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[4-[[4-(benzoylamino)-3-chloro-phenyl]methyl]-2-chloro-phenyl]benzamide
  • N-[2-chloro-4-[[3-chloro-4-[(oxo-phenylmethyl)amino]phenyl]methyl]phenyl]benzamide
  • N-[4-[4-(benzoylamino)-3-chloro-benzyl]-2-chloro-phenyl]benzamide
  • N-[2-chloro-4-[[3-chloro-4-(phenylcarbonylamino)phenyl]methyl]phenyl]benzamide
  • Oprea1_864119
  • BAS 00025210
  • ZINC02819992
  • CBMicro_013330
  • BIM-0013224.P001
  • Oprea1_827576

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0511 0.5591 0.5503
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0271 0.2507 0.4483
Plasmodium falciparum multidrug resistance protein 2 0.0271 0.2507 0.2166
Trypanosoma cruzi ABC transporter, putative 0.0091 0.0194 0.0348
Schistosoma mansoni tar DNA-binding protein 0.0768 0.8903 0.8903
Loa Loa (eye worm) TAR-binding protein 0.0768 0.8903 0.8903
Entamoeba histolytica P-glycoprotein 5, putative 0.0853 1 1
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0511 0.5591 1
Echinococcus granulosus multidrug resistance protein 1 0.0597 0.6707 0.6663
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0271 0.2507 0.4483
Trichomonas vaginalis abcb9, putative 0.0853 1 1
Brugia malayi hypothetical protein 0.0156 0.1028 0.1028
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0853 1 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0271 0.2507 0.0253
Trypanosoma brucei ATP-binding cassette protein, putative 0.0511 0.5591 1
Loa Loa (eye worm) hypothetical protein 0.0187 0.1424 0.1424
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0597 0.6707 0.5717
Plasmodium vivax multidrug resistance-associated protein 2, putative 0.0271 0.2507 0.2166
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0271 0.2507 0.2358
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0853 1 1
Schistosoma mansoni ABC transporter 0.0434 0.461 0.461
Loa Loa (eye worm) hypothetical protein 0.0853 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0235 0.2043 0.2043
Brugia malayi ABC transporter 0.0256 0.2312 0.2312
Schistosoma mansoni multidrug resistance protein 0.0853 1 1
Trichomonas vaginalis ABC transporter, putative 0.0853 1 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0853 1 1
Brugia malayi RNA binding protein 0.0768 0.8903 0.8903
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0853 1 1
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0271 0.2507 0.4285
Schistosoma mansoni tar DNA-binding protein 0.0768 0.8903 0.8903
Entamoeba histolytica P-glycoprotein-2 0.0853 1 1
Entamoeba histolytica P-glycoprotein 6, putative 0.0271 0.2507 0.2507
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0271 0.2507 0.4483
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0853 1 1
Schistosoma mansoni hypothetical protein 0.0187 0.1424 0.1424
Entamoeba histolytica hypothetical protein 0.0271 0.2507 0.2507
Entamoeba histolytica P-glyco protein 6, putative 0.0853 1 1
Trypanosoma cruzi ABC transporter, putative 0.0511 0.5591 1
Schistosoma mansoni hypothetical protein 0.0086 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0271 0.2507 0.2507
Entamoeba histolytica ATP-binding cassette protein, putative 0.0271 0.2507 0.2507
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0271 0.2507 0.2507
Loa Loa (eye worm) RNA binding protein 0.0768 0.8903 0.8903
Trichomonas vaginalis ABC transporter, putative 0.0853 1 1
Trichomonas vaginalis ABC transporter, putative 0.0853 1 1
Plasmodium falciparum ABC transporter G family member 2 0.0511 0.5591 0.539
Wolbachia endosymbiont of Brugia malayi ABC-type protease secretion system, ATPase and permease component, AprD 0.0271 0.2507 0.5
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0271 0.2507 0.4285
Plasmodium vivax multidrug resistance protein 1, putative 0.0853 1 1
Schistosoma mansoni multidrug resistance protein 0.0256 0.2312 0.2312
Echinococcus granulosus multidrug resistance protein 1 0.0853 1 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0853 1 1
Plasmodium vivax ABC transporter B family member 4, putative 0.0271 0.2507 0.2166
Brugia malayi hypothetical protein 0.011 0.0435 0.0435
Loa Loa (eye worm) hypothetical protein 0.0256 0.2312 0.2312
Plasmodium vivax ABC transporter B family member 6, putative 0.0271 0.2507 0.2166
Giardia lamblia Multidrug resistance-associated protein 1 0.0271 0.2507 0.063
Trichomonas vaginalis taga, putative 0.0853 1 1
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0271 0.2507 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0853 1 1
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0271 0.2507 0.2507
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0853 1 1
Plasmodium vivax multidrug resistance protein 2, putative 0.0271 0.2507 0.2166
Brugia malayi MH2 domain containing protein 0.039 0.4042 0.4042
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0853 1 1
Echinococcus multilocularis ATP binding cassette sub family B 0.0838 0.9806 0.9803
Loa Loa (eye worm) transcription factor SMAD2 0.039 0.4042 0.4042
Leishmania major hypothetical protein, conserved 0.011 0.0435 0.0245
Loa Loa (eye worm) latrophilin receptor protein 2 0.0086 0.0132 0.0132
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0853 1 1
Echinococcus multilocularis multidrug resistance protein 1 0.0597 0.6707 0.6663
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0235 0.2043 0.2043
Echinococcus multilocularis multidrug resistance protein 1 0.0853 1 1
Echinococcus granulosus multidrug resistance protein 1 0.0853 1 1
Plasmodium vivax ABC transporter B family member 5, putative 0.0271 0.2507 0.2166
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0853 1 0.5
Brugia malayi ABC transporter transmembrane region family protein 0.0256 0.2312 0.2312
Mycobacterium ulcerans drugs-transport transmembrane ATP-binding protein ABC transporter 0.0271 0.2507 0.4483
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.0271 0.2507 0.2166
Schistosoma mansoni multidrug resistance protein 0.0271 0.2507 0.2507
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0853 1 1
Plasmodium falciparum ABC transporter B family member 4, putative 0.0271 0.2507 0.2166
Giardia lamblia MRP-like ABC transporter 0.0271 0.2507 0.063
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0853 1 1
Schistosoma mansoni multidrug resistance protein 0.0271 0.2507 0.2507
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0271 0.2507 0.2358
Schistosoma mansoni tar DNA-binding protein 0.0768 0.8903 0.8903
Schistosoma mansoni multidrug resistance protein 0.0853 1 1
Brugia malayi ABC transporter transmembrane region family protein 0.0271 0.2507 0.2507
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0256 0.2312 0.2312
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0271 0.2507 0.4483
Loa Loa (eye worm) hypothetical protein 0.0256 0.2312 0.2312
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0271 0.2507 0.2358
Loa Loa (eye worm) MH2 domain-containing protein 0.039 0.4042 0.4042
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0853 1 1
Leishmania major p-glycoprotein 0.0853 1 1
Leishmania major ATP-binding cassette protein subfamily B, member 1, putative 0.0271 0.2507 0.2358
Schistosoma mansoni multidrug resistance protein 0.0271 0.2507 0.2507
Schistosoma mansoni hypothetical protein 0.0086 0.0132 0.0132
Schistosoma mansoni smdr2 0.0853 1 1
Entamoeba histolytica P-glycoprotein-2, putative 0.0256 0.2312 0.2312
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0853 1 1
Echinococcus granulosus multidrug resistance protein 1 0.0597 0.6707 0.6663
Plasmodium falciparum ABC transporter B family member 3, putative 0.0271 0.2507 0.2166
Schistosoma mansoni tar DNA-binding protein 0.0768 0.8903 0.8903
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0853 1 1
Trichomonas vaginalis ABC transporter, putative 0.0853 1 1
Entamoeba histolytica P-glycoprotein-1 0.0853 1 1
Toxoplasma gondii ATP-binding cassette sub-family B member 5 0.0271 0.2507 0.2358
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0511 0.5591 0.5591
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0273 0.2536 0.2536
Leishmania major p-glycoprotein e 0.0271 0.2507 0.2358
Giardia lamblia ABC transporter 0.0495 0.5396 1
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0511 0.5591 0.5503
Echinococcus granulosus multidrug resistance associated protein 7 0.0271 0.2507 0.2406
Brugia malayi ABC transporter family protein 0.0271 0.2507 0.2507
Trypanosoma brucei multidrug resistance protein E 0.0271 0.2507 0.4285
Toxoplasma gondii ABC transporter, putative 0.0271 0.2507 0.2358
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0853 1 1
Schistosoma mansoni hypothetical protein 0.0419 0.4416 0.4416
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0271 0.2507 0.2358
Brugia malayi multidrug resistance related protein 1 0.0271 0.2507 0.2507
Echinococcus granulosus ATP binding cassette sub family G 0.0511 0.5591 0.5532
Entamoeba histolytica P-glycoprotein 6, putative 0.0271 0.2507 0.2507
Brugia malayi ABC transporter family protein 0.0434 0.461 0.461
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0853 1 1
Brugia malayi ABC transporter transmembrane region family protein 0.0271 0.2507 0.2507
Loa Loa (eye worm) hypothetical protein 0.011 0.0435 0.0435
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0853 1 1
Leishmania major ATP-binding cassette protein subfamily C, member 8, putative 0.0271 0.2507 0.2358
Echinococcus multilocularis 0.0271 0.2507 0.2406
Loa Loa (eye worm) pax transcription factor protein 2 0.0249 0.2218 0.2218
Entamoeba histolytica ABC transporter, putative 0.0271 0.2507 0.2507
Schistosoma mansoni multidrug resistance protein 0.0853 1 1
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0838 0.9806 0.9803
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0511 0.5591 1
Echinococcus granulosus multidrug resistance protein 1 0.0853 1 1
Schistosoma mansoni hypothetical protein 0.0086 0.0132 0.0132
Entamoeba histolytica multidrug resistance protein, putative 0.0271 0.2507 0.2507
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0853 1 1
Entamoeba histolytica ATP-binding cassette protein, putative 0.0271 0.2507 0.2507
Trypanosoma brucei ABC transporter, putative 0.0511 0.5591 1
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0271 0.2507 0.2358
Echinococcus multilocularis ATP binding cassette sub family G 0.0511 0.5591 0.5532
Trypanosoma brucei p-glycoprotein 0.0271 0.2507 0.4285
Mycobacterium tuberculosis Probable drugs-transport transmembrane ATP-binding protein ABC transporter 0.0271 0.2507 0.2507
Plasmodium vivax ABC transporter B family member 3, putative 0.0271 0.2507 0.2166
Loa Loa (eye worm) multidrug resistance protein 3 0.0853 1 1
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0853 1 1
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0271 0.2507 0.2358
Echinococcus granulosus ATP binding cassette sub family B 0.0271 0.2507 0.2406
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0271 0.2507 0.4483
Plasmodium falciparum multidrug resistance protein 1 0.0853 1 1
Echinococcus multilocularis ATP binding cassette sub family B 0.0271 0.2507 0.2406
Entamoeba histolytica P-glycoprotein-5 0.0853 1 1
Echinococcus granulosus ATP binding cassette sub family G 0.0511 0.5591 0.5532
Mycobacterium leprae PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER 0.0271 0.2507 1
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0853 1 1
Trypanosoma cruzi PAB1-binding protein , putative 0.011 0.0435 0.0778
Entamoeba histolytica P-glycoprotein-2 0.0853 1 1
Entamoeba histolytica ATP-binding cassette protein, putative 0.0271 0.2507 0.2507
Trypanosoma brucei ABC transporter, mitochondrial, putative 0.0271 0.2507 0.4285
Onchocerca volvulus 0.0853 1 1
Toxoplasma gondii LsmAD domain-containing protein 0.011 0.0435 0.0245
Trypanosoma brucei PAB1-binding protein , putative 0.011 0.0435 0.0446
Trichomonas vaginalis abcb9, putative 0.0853 1 1
Trypanosoma cruzi PAB1-binding protein , putative 0.011 0.0435 0.0778
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0853 1 1
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0511 0.5591 0.5503
Plasmodium falciparum multidrug resistance-associated protein 1 0.0271 0.2507 0.2166
Schistosoma mansoni multidrug resistance protein 0.0271 0.2507 0.2507
Brugia malayi ABC transporter family protein 0.0271 0.2507 0.2507
Plasmodium falciparum multidrug resistance-associated protein 2 0.0271 0.2507 0.2166
Trypanosoma brucei ABC transporter of the mitochondrion, putative 0.0271 0.2507 0.4285
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0271 0.2507 0.4483
Echinococcus multilocularis multidrug resistance associated protein 7 0.0271 0.2507 0.2406
Loa Loa (eye worm) ABC transporter 0.0271 0.2507 0.2507
Plasmodium falciparum ABC transporter B family member 5, putative 0.0271 0.2507 0.2166
Loa Loa (eye worm) hypothetical protein 0.0273 0.2536 0.2536
Loa Loa (eye worm) ABC transporter 0.0271 0.2507 0.2507
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0853 1 1
Loa Loa (eye worm) ABC transporter 0.0434 0.461 0.461
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0271 0.2507 0.2358
Onchocerca volvulus 0.0249 0.2218 0.1327
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0235 0.2043 0.1936
Mycobacterium ulcerans component linked with the assembly of cytochrome transport transmembrane ATP-binding protein ABC transporter CydD 0.0271 0.2507 0.4483
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0271 0.2507 0.2358
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0235 0.2043 0.1936
Loa Loa (eye worm) hypothetical protein 0.0271 0.2507 0.2507
Echinococcus multilocularis ATP binding cassette sub family G 0.0511 0.5591 0.5532
Giardia lamblia ABC transporter, putative 0.0271 0.2507 0.063
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0853 1 1
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0853 1 1
Brugia malayi latrophilin 2 splice variant baaae 0.0187 0.1424 0.1424
Brugia malayi P-glycoprotein-like protein 0.0271 0.2507 0.2507
Brugia malayi RNA recognition motif domain containing protein 0.0768 0.8903 0.8903
Schistosoma mansoni hypothetical protein 0.0086 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0838 0.9806 0.9806
Brugia malayi ABC transporter family protein 0.0853 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.0091 0.0194 0.0348
Schistosoma mansoni tar DNA-binding protein 0.0768 0.8903 0.8903
Brugia malayi ABC transporter 0.0271 0.2507 0.2507
Echinococcus granulosus multidrug resistance associated protein 1 0.0271 0.2507 0.2406
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0853 1 1
Echinococcus multilocularis multidrug resistance protein 1 0.0853 1 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0273 0.2536 0.2536
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0853 1 1
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0271 0.2507 0.4483
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0235 0.2043 0.1936
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0853 1 1
Wolbachia endosymbiont of Brugia malayi ABC-type multidrug transport system, ATPase and permease component 0.0271 0.2507 0.5
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0853 1 1
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0419 0.4416 0.4416
Brugia malayi hypothetical protein 0.0271 0.2507 0.2507
Echinococcus multilocularis ATP binding cassette sub family B 0.0271 0.2507 0.2406
Plasmodium falciparum ABC transporter B family member 7, putative 0.0271 0.2507 0.2166
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0853 1 1
Plasmodium falciparum ABC transporter B family member 6, putative 0.0271 0.2507 0.2166
Mycobacterium tuberculosis Iron-regulated transporter IrtA 0.0271 0.2507 0.2507
Brugia malayi Latrophilin receptor protein 2 0.0086 0.0132 0.0132
Leishmania major pentamidine resistance protein 1 0.0271 0.2507 0.2358
Schistosoma mansoni multidrug resistance protein 0.0271 0.2507 0.2507
Echinococcus granulosus tar DNA binding protein 0.0768 0.8903 0.8888
Loa Loa (eye worm) hypothetical protein 0.0853 1 1
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0271 0.2507 0.2358
Brugia malayi Pax transcription factor protein 2 0.0249 0.2218 0.2218
Trypanosoma cruzi ATP-binding cassette protein subfamily G 0.0091 0.0194 0.0348
Echinococcus granulosus ATP binding cassette sub family G 0.0511 0.5591 0.5532
Echinococcus granulosus ATP binding cassette sub family B 0.0271 0.2507 0.2406
Brugia malayi ABC transporter family protein 0.0271 0.2507 0.2507
Entamoeba histolytica ATP-binding cassette protein, putative 0.0271 0.2507 0.2507
Leishmania major ATP-binding cassette protein subfamily B, member 3, putative 0.0271 0.2507 0.2358
Loa Loa (eye worm) hypothetical protein 0.0156 0.1028 0.1028
Loa Loa (eye worm) hypothetical protein 0.0086 0.0132 0.0132
Leishmania major ABC-thiol transporter 0.0271 0.2507 0.2358
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0235 0.2043 0.2043
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0086 0.0132 0.0132
Giardia lamblia Multidrug resistance-associated protein 1 0.0271 0.2507 0.063
Echinococcus multilocularis ATP binding cassette sub family B 0.0271 0.2507 0.2406
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0235 0.2043 0.2043
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0235 0.2043 0.1936
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0511 0.5591 1
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0853 1 1
Entamoeba histolytica P-glycoprotein 5, putative 0.0256 0.2312 0.2312
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0853 1 1
Echinococcus multilocularis tar DNA binding protein 0.0768 0.8903 0.8888
Loa Loa (eye worm) ABC transporter 0.0271 0.2507 0.2507
Brugia malayi Calcitonin receptor-like protein seb-1 0.0273 0.2536 0.2536
Plasmodium vivax ABC transporter B family member 7, putative 0.0271 0.2507 0.2166
Echinococcus multilocularis ATP binding cassette sub family G 0.0511 0.5591 0.5532
Toxoplasma gondii ABC transporter family protein 0.0271 0.2507 0.2358
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0271 0.2507 0.2507
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0853 1 1
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0853 1 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0235 0.2043 0.2043
Trypanosoma cruzi hypothetical protein, conserved 0.0091 0.0194 0.0348
Entamoeba histolytica P-glycoprotein-2, putative 0.0853 1 1
Echinococcus granulosus ATP binding cassette sub family B 0.0256 0.2312 0.2209
Trypanosoma cruzi multidrug resistance protein E, putative 0.0271 0.2507 0.4483
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0853 1 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0768 0.8903 0.8903
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0853 1 1
Trichomonas vaginalis abcb9, putative 0.0853 1 1
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0271 0.2507 0.2358
Trypanosoma cruzi ATP-binding cassette protein subfamily G 0.0091 0.0194 0.0348
Plasmodium vivax ABC transporter G family member 2, putative 0.0511 0.5591 0.539
Entamoeba histolytica ABC transporter, putative 0.0511 0.5591 0.5591
Echinococcus multilocularis multidrug resistance associated protein 1 0.0271 0.2507 0.2406
Echinococcus multilocularis ATP binding cassette sub family B 0.0271 0.2507 0.2406
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0511 0.5591 1
Loa Loa (eye worm) hypothetical protein 0.0271 0.2507 0.2507
Schistosoma mansoni smdr1 0.0271 0.2507 0.2507
Brugia malayi TAR-binding protein 0.0768 0.8903 0.8903

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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