Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0185 | 0.1483 | 0.1483 |
Trypanosoma cruzi | carnitine O-acetyltransferase, putative | 0.0027 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1093 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0104 | 0.0725 | 0.0725 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.1483 | 0.1483 |
Echinococcus multilocularis | neuroligin | 0.0185 | 0.1483 | 0.1483 |
Echinococcus granulosus | carboxylesterase 5A | 0.1093 | 1 | 1 |
Echinococcus granulosus | choline O acetyltransferase | 0.0178 | 0.1417 | 0.1417 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0027 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0185 | 0.1483 | 0.1483 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0185 | 0.1483 | 0.1483 |
Loa Loa (eye worm) | carboxylesterase | 0.0185 | 0.1483 | 0.1483 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0027 | 0 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0185 | 0.1483 | 0.1483 |
Trypanosoma cruzi | choline/carnitine O-acetyltransferase, putative | 0.0027 | 0 | 0.5 |
Brugia malayi | Choline O-acetyltransferase | 0.0178 | 0.1417 | 0.1417 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1093 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0185 | 0.1483 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.1093 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.1483 | 0.1483 |
Onchocerca volvulus | 0.0185 | 0.1483 | 1 | |
Schistosoma mansoni | acetylcholinesterase | 0.0185 | 0.1483 | 0.1483 |
Loa Loa (eye worm) | hypothetical protein | 0.1093 | 1 | 1 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0185 | 0.1483 | 0.1483 |
Onchocerca volvulus | 0.0185 | 0.1483 | 1 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0185 | 0.1483 | 0.1483 |
Brugia malayi | Carboxylesterase family protein | 0.0185 | 0.1483 | 0.1483 |
Brugia malayi | Choline O-acetyltransferase | 0.0178 | 0.1417 | 0.1417 |
Echinococcus granulosus | acetylcholinesterase | 0.1093 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.1483 | 0.1483 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0185 | 0.1483 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0725 | 0.0725 |
Brugia malayi | Carboxylesterase family protein | 0.0185 | 0.1483 | 0.1483 |
Leishmania major | choline/Carnitine o-acyltransferase-like protein | 0.0027 | 0 | 0.5 |
Onchocerca volvulus | 0.0185 | 0.1483 | 1 | |
Echinococcus granulosus | BC026374 protein S09 family | 0.0185 | 0.1483 | 0.1483 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0185 | 0.1483 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.1093 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0725 | 0.0725 |
Onchocerca volvulus | 0.0104 | 0.0725 | 0.4888 | |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.1417 | 0.1417 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0027 | 0 | 0.5 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0185 | 0.1483 | 0.1483 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0185 | 0.1483 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0185 | 0.1483 | 0.1483 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0185 | 0.1483 | 0.1483 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0104 | 0.0725 | 0.0725 |
Loa Loa (eye worm) | hypothetical protein | 0.1093 | 1 | 1 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0027 | 0 | 0.5 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0185 | 0.1483 | 0.1483 |
Brugia malayi | Trypsin family protein | 0.0104 | 0.0725 | 0.0725 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.1483 | 0.1483 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0185 | 0.1483 | 0.1483 |
Loa Loa (eye worm) | carboxylesterase | 0.1093 | 1 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0185 | 0.1483 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.1483 | 0.1483 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.1483 | 0.1483 |
Echinococcus granulosus | acetylcholinesterase | 0.1093 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0185 | 0.1483 | 0.5 |
Onchocerca volvulus | 0.0185 | 0.1483 | 1 | |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0185 | 0.1483 | 0.1483 |
Leishmania major | carnitine/choline acetyltransferase, putative | 0.0027 | 0 | 0.5 |
Schistosoma mansoni | choline o-acyltransferase | 0.0178 | 0.1417 | 0.1417 |
Brugia malayi | Carboxylesterase family protein | 0.0185 | 0.1483 | 0.1483 |
Trypanosoma cruzi | carnitine/choline acetyltransferase, putative | 0.0027 | 0 | 0.5 |
Trypanosoma brucei | carnitine O-palmitoyltransferase, putative | 0.0027 | 0 | 0.5 |
Echinococcus multilocularis | choline O acetyltransferase | 0.0178 | 0.1417 | 0.1417 |
Trypanosoma cruzi | carnitine/choline acetyltransferase, putative | 0.0027 | 0 | 0.5 |
Onchocerca volvulus | 0.0092 | 0.0616 | 0.4156 | |
Schistosoma mansoni | gliotactin | 0.0185 | 0.1483 | 0.1483 |
Trypanosoma brucei | carnitine O-acetyltransferase, putative | 0.0027 | 0 | 0.5 |
Echinococcus granulosus | neuroligin | 0.0185 | 0.1483 | 0.1483 |
Loa Loa (eye worm) | choline O-acetyltransferase | 0.0178 | 0.1417 | 0.1417 |
Echinococcus multilocularis | acetylcholinesterase | 0.1093 | 1 | 1 |
Onchocerca volvulus | 0.0185 | 0.1483 | 1 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1093 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Leishmania major | carnitine palmitoyltransferase-like protein | 0.0027 | 0 | 0.5 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0027 | 0 | 0.5 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0185 | 0.1483 | 0.1483 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.1483 | 0.1483 |
Trypanosoma cruzi | carnitine O-palmitoyltransferase II, putative | 0.0027 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | Displacement of [125I]MIP-1beta from CCR5 expressed in CHO cell membrane | ChEMBL. | 19233649 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.