Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | purinergic receptor P2X, ligand-gated ion channel, 2 | Starlite/ChEMBL | References |
Rattus norvegicus | P2X purinoceptor 3 | Starlite/ChEMBL | References |
Homo sapiens | purinergic receptor P2X, ligand-gated ion channel, 3 | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | p2X purinoceptor 4 | 0.0246 | 0.0682 | 0.0682 |
Trypanosoma brucei | adenosine monophosphate deaminase, putative | 0.0229 | 0 | 0.5 |
Treponema pallidum | adenosine deaminase | 0.0477 | 1 | 0.5 |
Plasmodium vivax | adenosine deaminase, putative | 0.0477 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0477 | 1 | 1 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.0477 | 1 | 1 |
Leishmania major | adenine aminohydrolase | 0.0477 | 1 | 1 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0246 | 0.0682 | 0.0682 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0246 | 0.0682 | 0.0682 |
Loa Loa (eye worm) | hypothetical protein | 0.0302 | 0.2937 | 0.2937 |
Schistosoma mansoni | adenosine deaminase-related | 0.0477 | 1 | 1 |
Trypanosoma brucei | AMP deaminase, putative | 0.0229 | 0 | 0.5 |
Trypanosoma brucei | AMP deaminase, putative | 0.0229 | 0 | 0.5 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0477 | 1 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0477 | 1 | 1 |
Schistosoma mansoni | P2X receptor subunit | 0.0246 | 0.0682 | 0.0682 |
Loa Loa (eye worm) | hypothetical protein | 0.0302 | 0.2937 | 0.2937 |
Loa Loa (eye worm) | hypothetical protein | 0.0302 | 0.2937 | 0.2937 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0246 | 0.0682 | 0.0682 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0229 | 0 | 0.5 |
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.0477 | 1 | 0.5 |
Trypanosoma brucei | AMP deaminase, putative | 0.0229 | 0 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0477 | 1 | 1 |
Schistosoma mansoni | adenosine deaminase | 0.0477 | 1 | 1 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0229 | 0 | 0.5 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0246 | 0.0682 | 0.0682 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0477 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0302 | 0.2937 | 0.2937 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0229 | 0 | 0.5 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0246 | 0.0682 | 0.0682 |
Echinococcus granulosus | adenosine deaminase | 0.0477 | 1 | 1 |
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.0477 | 1 | 0.5 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0477 | 1 | 0.5 |
Schistosoma mansoni | P2X receptor subunit | 0.0246 | 0.0682 | 0.0682 |
Plasmodium falciparum | adenosine deaminase | 0.0477 | 1 | 1 |
Echinococcus multilocularis | adenosine deaminase | 0.0477 | 1 | 1 |
Trypanosoma cruzi | adenosine monophosphate deaminase-like protein, putative | 0.0229 | 0 | 0.5 |
Schistosoma mansoni | P2X receptor subunit | 0.0246 | 0.0682 | 0.0682 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0477 | 1 | 1 |
Trypanosoma cruzi | adenosine monophosphate deaminase, putative | 0.0229 | 0 | 0.5 |
Mycobacterium ulcerans | adenosine deaminase | 0.0477 | 1 | 0.5 |
Schistosoma mansoni | P2X receptor subunit | 0.0246 | 0.0682 | 0.0682 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0229 | 0 | 0.5 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0229 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.