Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Pre-SET motif family protein | 0.0423 | 0.1668 | 0.2983 |
Brugia malayi | RNA binding protein | 0.026 | 0.0969 | 0.1734 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0053 | 0.0082 | 0.0769 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.011 | 0.0324 | 0.0297 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0076 | 0.0053 |
Echinococcus granulosus | lamin | 0.0197 | 0.0699 | 0.0673 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0047 | 0.0053 | 0.0025 |
Brugia malayi | AMP-binding enzyme family protein | 0.0053 | 0.0082 | 0.0147 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0307 | 0.1168 | 0.8871 |
Echinococcus granulosus | geminin | 0.0186 | 0.0652 | 0.0626 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.1339 | 0.5591 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.026 | 0.0969 | 0.1028 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0047 | 0.0053 | 0.0294 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.0113 | 0.0093 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0047 | 0.0053 | 0.0027 |
Trichomonas vaginalis | chromobox protein, putative | 0.0073 | 0.0165 | 0.0607 |
Schistosoma mansoni | thyroid hormone receptor | 0.0286 | 0.1077 | 0.1145 |
Schistosoma mansoni | lamin | 0.0197 | 0.0699 | 0.0733 |
Brugia malayi | MH2 domain containing protein | 0.1339 | 0.5591 | 1 |
Echinococcus multilocularis | smad | 0.0091 | 0.0244 | 0.0217 |
Onchocerca volvulus | Huntingtin homolog | 0.0135 | 0.0431 | 0.2131 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0057 | 0.0029 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0091 | 0.0244 | 0.0217 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0047 | 0.0053 | 0.0128 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.026 | 0.0969 | 0.1698 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0053 | 0.0082 | 0.0769 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0197 | 0.0699 | 0.1251 |
Brugia malayi | RNA recognition motif domain containing protein | 0.026 | 0.0969 | 0.1734 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0052 | 0.0076 | 0.0136 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0047 | 0.0053 | 0.0712 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0059 | 0.0104 | 0.0076 |
Schistosoma mansoni | chromobox protein | 0.0073 | 0.0165 | 0.015 |
Echinococcus granulosus | intermediate filament protein | 0.0197 | 0.0699 | 0.0673 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.0057 | 0.0029 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0057 | 0.0032 |
Schistosoma mansoni | hypothetical protein | 0.0112 | 0.0335 | 0.0335 |
Loa Loa (eye worm) | hypothetical protein | 0.0194 | 0.0684 | 0.1185 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0047 | 0.0053 | 0.5 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0047 | 0.0053 | 0.011 |
Schistosoma mansoni | hypothetical protein | 0.011 | 0.0324 | 0.0323 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0028 | 0.0001 |
Plasmodium falciparum | thioredoxin reductase | 0.0135 | 0.043 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0053 | 0.0082 | 0.0147 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0091 | 0.0244 | 0.0217 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0061 | 0.0113 | 0.0086 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0307 | 0.1168 | 0.8871 |
Loa Loa (eye worm) | hypothetical protein | 0.0347 | 0.1338 | 0.2361 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0076 | 0.0053 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0052 | 0.0076 | 0.0048 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0053 | 0.0082 | 0.0255 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0053 | 0.0082 | 0.0769 |
Brugia malayi | glutaminase DH11.1 | 0.0568 | 0.2288 | 0.4092 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.0324 | 1 |
Echinococcus multilocularis | musashi | 0.0197 | 0.0699 | 0.0673 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0347 | 0.1338 | 0.1431 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0135 | 0.0432 | 0.0405 |
Brugia malayi | MH2 domain containing protein | 0.0091 | 0.0244 | 0.0437 |
Echinococcus multilocularis | chromobox protein 1 | 0.0073 | 0.0165 | 0.0138 |
Leishmania major | trypanothione reductase | 0.0135 | 0.043 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0341 | 0.1315 | 1 |
Brugia malayi | glutathione reductase | 0.0135 | 0.043 | 0.0769 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0164 | 0.0557 | 0.0997 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0106 | 0.0307 | 0.0507 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0052 | 0.0076 | 0.0048 |
Schistosoma mansoni | hypothetical protein | 0.0186 | 0.0652 | 0.0682 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0164 | 0.0557 | 0.0958 |
Brugia malayi | Pre-SET motif family protein | 0.0061 | 0.0113 | 0.0203 |
Trichomonas vaginalis | glutaminase, putative | 0.0568 | 0.2288 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0082 | 0.0104 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0057 | 0.0029 |
Trichomonas vaginalis | set domain proteins, putative | 0.0482 | 0.1918 | 0.8365 |
Brugia malayi | chromobox protein homolog 3 | 0.0041 | 0.0028 | 0.005 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0047 | 0.0053 | 0.0128 |
Onchocerca volvulus | 0.0053 | 0.0082 | 0.0286 | |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.0057 | 0.0059 |
Brugia malayi | MH1 domain containing protein | 0.0091 | 0.0244 | 0.0437 |
Onchocerca volvulus | 0.0347 | 0.1338 | 0.6933 | |
Schistosoma mansoni | glutaminase | 0.0568 | 0.2288 | 0.2468 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0053 | 0.0082 | 0.0255 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0307 | 0.1168 | 0.8871 |
Echinococcus granulosus | microtubule associated protein 2 | 0.2178 | 0.9183 | 0.9181 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0341 | 0.1315 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.0057 | 0.0102 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0041 | 0.0028 | 0.005 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0091 | 0.0244 | 0.0217 |
Brugia malayi | MH1 domain containing protein | 0.0091 | 0.0244 | 0.0437 |
Loa Loa (eye worm) | hypothetical protein | 0.0197 | 0.0699 | 0.1213 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0254 | 0.0942 | 0.0916 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0135 | 0.0432 | 0.0405 |
Schistosoma mansoni | tar DNA-binding protein | 0.026 | 0.0969 | 0.1028 |
Schistosoma mansoni | hypothetical protein | 0.0254 | 0.0942 | 0.0998 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0423 | 0.1668 | 0.2952 |
Echinococcus multilocularis | tar DNA binding protein | 0.026 | 0.0969 | 0.0944 |
Mycobacterium ulcerans | hypothetical protein | 0.0053 | 0.0082 | 0.0255 |
Brugia malayi | Smad1 | 0.0091 | 0.0244 | 0.0437 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0091 | 0.0244 | 0.0217 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.011 | 0.0324 | 0.0323 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0095 | 0.0262 | 0.0234 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0053 | 0.0082 | 0.0517 |
Loa Loa (eye worm) | glutaminase 2 | 0.0568 | 0.2288 | 0.4066 |
Brugia malayi | MH1 domain containing protein | 0.005 | 0.0069 | 0.0124 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0069 | 0.0081 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0041 | 0.0028 | 0.0007 |
Echinococcus multilocularis | lamin dm0 | 0.0197 | 0.0699 | 0.0673 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0197 | 0.0699 | 0.1213 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0112 | 0.0335 | 0.0599 |
Schistosoma mansoni | Smad4 | 0.0091 | 0.0244 | 0.0236 |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.0041 | 0.0059 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0053 | 0.0082 | 0.0255 |
Schistosoma mansoni | thyroid hormone receptor | 0.0286 | 0.1077 | 0.1145 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0047 | 0.0053 | 0.5 |
Onchocerca volvulus | 0.0197 | 0.0699 | 0.3552 | |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.0324 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.1339 | 0.5591 | 1 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0047 | 0.0053 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0082 | 0.0104 |
Schistosoma mansoni | microtubule-associated protein tau | 0.2178 | 0.9183 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0073 | 0.0165 | 0.0607 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0091 | 0.0244 | 0.0395 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0052 | 0.0076 | 0.0048 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0341 | 0.1315 | 1 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0073 | 0.0165 | 0.0254 |
Brugia malayi | TAR-binding protein | 0.026 | 0.0969 | 0.1734 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0061 | 0.0113 | 0.0086 |
Onchocerca volvulus | 0.0073 | 0.0165 | 0.0723 | |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0053 | 0.0082 | 0.0517 |
Schistosoma mansoni | smad1 5 8 and | 0.0091 | 0.0244 | 0.0236 |
Echinococcus multilocularis | lamin | 0.0197 | 0.0699 | 0.0673 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0053 | 0.0082 | 0.0255 |
Toxoplasma gondii | thioredoxin reductase | 0.0135 | 0.043 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0197 | 0.0699 | 0.0673 |
Echinococcus granulosus | smad | 0.0091 | 0.0244 | 0.0217 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0044 | 0.0041 | 0.0071 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0076 | 0.0093 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.004 | 0.0024 | 0.0072 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0254 | 0.0942 | 0.0916 |
Plasmodium vivax | SET domain protein, putative | 0.0061 | 0.0113 | 0.2202 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0053 | 0.0082 | 0.0255 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0047 | 0.0053 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0246 | 0.0399 |
Brugia malayi | hypothetical protein | 0.011 | 0.0324 | 0.0579 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.2178 | 0.9183 | 0.9181 |
Loa Loa (eye worm) | glutaminase | 0.0568 | 0.2288 | 0.4066 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0307 | 0.1168 | 0.8871 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0164 | 0.0557 | 0.0997 |
Schistosoma mansoni | tar DNA-binding protein | 0.026 | 0.0969 | 0.1028 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0047 | 0.0053 | 0.0095 |
Plasmodium vivax | glutathione reductase, putative | 0.0135 | 0.043 | 1 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0047 | 0.0053 | 0.0712 |
Echinococcus granulosus | tar DNA binding protein | 0.026 | 0.0969 | 0.0944 |
Schistosoma mansoni | smad1 5 8 and | 0.0091 | 0.0244 | 0.0236 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0135 | 0.043 | 1 |
Echinococcus multilocularis | Smad4 | 0.0091 | 0.0244 | 0.0217 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0106 | 0.0307 | 0.0548 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0113 | 0.016 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0028 | 0.0007 |
Plasmodium falciparum | glutathione reductase | 0.0135 | 0.043 | 1 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0095 | 0.0262 | 0.0234 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0052 | 0.0076 | 0.0093 |
Brugia malayi | hypothetical protein | 0.0135 | 0.0431 | 0.0771 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0047 | 0.0053 | 0.0128 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0307 | 0.1168 | 0.8871 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.075 | 0.3065 | 0.3045 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0135 | 0.043 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0057 | 0.0032 |
Echinococcus multilocularis | GPCR, family 2 | 0.0052 | 0.0076 | 0.0048 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0047 | 0.0053 | 0.0712 |
Echinococcus granulosus | GPCR family 2 | 0.0052 | 0.0076 | 0.0048 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0076 | 0.0053 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0061 | 0.0113 | 0.1604 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0052 | 0.0076 | 0.0048 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0047 | 0.0053 | 0.0712 |
Brugia malayi | AMP-binding enzyme family protein | 0.0053 | 0.0082 | 0.0147 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0041 | 0.0028 | 0.0007 |
Echinococcus granulosus | chromobox protein 1 | 0.0073 | 0.0165 | 0.0138 |
Loa Loa (eye worm) | glutathione reductase | 0.0135 | 0.043 | 0.0729 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0091 | 0.0244 | 0.0395 |
Schistosoma mansoni | chromobox protein | 0.0073 | 0.0165 | 0.015 |
Mycobacterium tuberculosis | Probable reductase | 0.0307 | 0.1168 | 0.8871 |
Brugia malayi | Thioredoxin reductase | 0.0135 | 0.043 | 0.0769 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0082 | 0.0104 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.0057 | 0.0032 |
Brugia malayi | intermediate filament protein | 0.0197 | 0.0699 | 0.1251 |
Echinococcus multilocularis | chromobox protein 1 | 0.0073 | 0.0165 | 0.0138 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0286 | 0.1077 | 0.1052 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0073 | 0.0165 | 0.0149 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.0324 | 1 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0341 | 0.1315 | 1 |
Brugia malayi | Heterochromatin protein 1 | 0.0073 | 0.0165 | 0.0296 |
Entamoeba histolytica | hypothetical protein | 0.011 | 0.0324 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0047 | 0.0053 | 0.0712 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.0431 | 0.0731 |
Schistosoma mansoni | tar DNA-binding protein | 0.026 | 0.0969 | 0.1028 |
Schistosoma mansoni | intermediate filament proteins | 0.0197 | 0.0699 | 0.0733 |
Brugia malayi | MH2 domain containing protein | 0.0091 | 0.0244 | 0.0437 |
Treponema pallidum | NADH oxidase | 0.0047 | 0.0053 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.0431 | 0.0731 |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.0041 | 0.0059 |
Mycobacterium ulcerans | glutaminase | 0.0568 | 0.2288 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0061 | 0.0113 | 0.0086 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0047 | 0.0053 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0076 | 0.0053 |
Echinococcus granulosus | Smad4 | 0.0091 | 0.0244 | 0.0217 |
Echinococcus granulosus | chromobox protein 1 | 0.0073 | 0.0165 | 0.0138 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0052 | 0.0076 | 0.0136 |
Loa Loa (eye worm) | RNA binding protein | 0.026 | 0.0969 | 0.1698 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.0113 | 0.0093 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.0557 | 0.0958 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0053 | 0.0082 | 0.0255 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0307 | 0.1168 | 0.881 |
Loa Loa (eye worm) | TAR-binding protein | 0.026 | 0.0969 | 0.1698 |
Schistosoma mansoni | smad1 5 8 and | 0.0091 | 0.0244 | 0.0236 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0053 | 0.0082 | 0.0255 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0047 | 0.0053 | 0.011 |
Schistosoma mansoni | hypothetical protein | 0.0186 | 0.0652 | 0.0682 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0091 | 0.0244 | 0.0236 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.0113 | 0.0093 |
Brugia malayi | MH2 domain containing protein | 0.0041 | 0.0028 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0092 | 0.0246 | 0.0399 |
Schistosoma mansoni | tar DNA-binding protein | 0.026 | 0.0969 | 0.1028 |
Brugia malayi | MH1 domain containing protein | 0.005 | 0.0069 | 0.0124 |
Loa Loa (eye worm) | intermediate filament protein | 0.0197 | 0.0699 | 0.1213 |
Schistosoma mansoni | smad | 0.0091 | 0.0244 | 0.0236 |
Loa Loa (eye worm) | Smad1 | 0.0091 | 0.0244 | 0.0395 |
Plasmodium falciparum | thioredoxin reductase | 0.0047 | 0.0053 | 0.0712 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0135 | 0.043 | 0.3191 |
Onchocerca volvulus | Huntingtin homolog | 0.0135 | 0.0431 | 0.2131 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0335 | 0.0558 |
Onchocerca volvulus | 0.0197 | 0.0699 | 0.3552 | |
Onchocerca volvulus | 0.0482 | 0.1918 | 1 | |
Echinococcus multilocularis | geminin | 0.0186 | 0.0652 | 0.0626 |
Loa Loa (eye worm) | nuclear factor I | 0.005 | 0.0069 | 0.0081 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.0057 | 0.0029 |
Trypanosoma brucei | trypanothione reductase | 0.0135 | 0.043 | 1 |
Schistosoma mansoni | lamin | 0.0197 | 0.0699 | 0.0733 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0262 | 0.0426 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.011 | 0.0324 | 0.0297 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0135 | 0.043 | 0.0729 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0028 | 0.0007 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.