Target list

Search results for query: PLoS NTD Query 4 (P. falciparum)

You can Modify weights (moves query to your history allowing re-weight functionality) to match your needs

  • Score for genes in query #90 (Mtb all proteins (now searched on pfa)): 1
  • Score for genes in query #80 (Mtb mwt <100kDa (now searched on pfa)): 20
  • Score for genes in query #79 (Mtb Pubmed (now searched on pfa)): 35
  • Score for genes in query #86 (Mtb any essentiality evidence (now searched on pfa)): 50
  • Score for genes in query #82 (Mtb PDB (now searched on pfa)): 50
  • Score for genes in query #88 (Mtb Compd desirability >0.3 (now searched on pfa)): 35
  • Score for genes in query #93 (Pfa in Pvi): 25
  • Score for genes in query #87 (Mtb dindex >=0.6 (now searched on pfa)): 35
  • Score for genes in query #85 (Mtb any genetic validation (now searched on pfa)): 50
  • Score for genes in query #78 (Mtb enz (EC + func. Categ.) (now searched on pfa)): 100
  • Score for genes in query #84 (Mtb not in humans (now searched on pfa)): 25
  • Score for genes in query #81 (Mtb no TM domain (now searched on pfa)): 20
  • Score for genes in query #89 (Mtb assayable (now searched on pfa)): 35
  • Score for genes in query #83 (Mtb modbase (now searched on pfa)): 30

Convert this list of targets into a list of drugs:

Compounds have been manually associated with targets based on literature curation (Curated), and transitively associated with known druggable homologs or direct orthologs (predicted). Network derived target prioritizations also allows to convert any gene list into a drug list by making use of gene-drug indirect relationships within the repurposing network. All associations are done with true positives (known druggable targets), but predicted interactions are by no means tested or experimentally validated.

Retrieve:

4804 records found | Showing page 3 of 193 (records 51-75) | Number of records to display | Find orthologs in

  Organism   Name     Ortholog group   Product Weight
P. falciparum   PF3D7_0510500   OG5_127702   topoisomerase I 351
P. falciparum   PF3D7_0920800   OG5_126887   inosine-5'-monophosphate dehydrogenase 351
P. falciparum   PF3D7_1246900   OG5_126635   RAC-beta serine/threonine protein kinase 351
P. falciparum   PF3D7_0801800   OG5_127555   mannose-6-phosphate isomerase, putative 346
P. falciparum   PF3D7_1453800   OG5_127121   glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 346
P. falciparum   PF3D7_1343000   OG5_132295   phosphoethanolamine N-methyltransferase 341
P. falciparum   PF3D7_1023200   OG5_126793   orotidine 5'-phosphate decarboxylase 341
P. falciparum   PF3D7_1462800   OG5_126628   glyceraldehyde-3-phosphate dehydrogenase 341
P. falciparum   PF3D7_0513300   OG5_130516   purine nucleoside phosphorylase 341
P. falciparum   PF3D7_0623200   OG5_133183   ferredoxin--NADP reductase 341
P. falciparum   PF3D7_1329400   OG5_126856   AMP deaminase, putative 336
P. falciparum   PF3D7_0808200   OG5_133546   plasmepsin X 336
P. falciparum   PF3D7_1323000   OG5_130367   beta-hydroxyacyl-ACP dehydratase 336
P. falciparum   PF3D7_1446200   OG5_127293   M17 leucyl aminopeptidase 336
P. falciparum   PF3D7_0618500   OG5_126911   malate dehydrogenase 336
P. falciparum   PF3D7_0932300   OG5_128020   M18 aspartyl aminopeptidase 336
P. falciparum   PF3D7_1239500   OG5_128755   DNA gyrase subunit B 336
P. falciparum   PF3D7_1247800   OG5_130494   dipeptidyl aminopeptidase 2 336
P. falciparum   PF3D7_1331100   OG5_153054   DNA polymerase theta, putative 331
P. falciparum   PF3D7_1017000   OG5_127429   DNA polymerase delta catalytic subunit 331
P. falciparum   PF3D7_1115300   OG5_126607   cysteine proteinase falcipain 2b 331
P. falciparum   PF3D7_1115400   OG5_126607   cysteine proteinase falcipain 3 331
P. falciparum   PF3D7_1120100   OG5_127491   phosphoglycerate mutase, putative 331
P. falciparum   PF3D7_1308200   OG5_126835   carbamoyl phosphate synthetase 331
P. falciparum   PF3D7_1309600   OG5_126871   ribosomal RNA methyltransferase, putative 331

Showing page 3 (records 51-75) of 193