Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | endothelin converting enzyme 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0887 | 0.0887 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0076 | 0.0076 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.2241 | 0.5565 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0054 | 0.1007 | 0.2501 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.2241 | 0.5565 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0084 | 0.2165 | 0.5376 |
Mycobacterium ulcerans | zinc metalloprotease | 0.0114 | 0.3306 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 0.0887 | 0.0245 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0051 | 0.0887 | 0.2201 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0114 | 0.3306 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.2165 | 0.5376 |
Echinococcus multilocularis | endothelin converting enzyme 1 | 0.0114 | 0.3306 | 0.4765 |
Echinococcus multilocularis | expressed conserved protein | 0.0049 | 0.0819 | 0.0118 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0076 | 0.0076 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 0.0887 | 0.0245 |
Schistosoma mansoni | Nep2 peptidase (M13 family) | 0.0058 | 0.1141 | 0.1141 |
Schistosoma mansoni | neprilysin | 0.003 | 0.0076 | 0.0076 |
Brugia malayi | hypothetical protein | 0.0049 | 0.0819 | 0.2032 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.3306 | 0.8208 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0187 | 0.6108 | 1 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0047 | 0.0756 | 0.0756 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0133 | 0.4028 | 1 |
Toxoplasma gondii | peptidase family M13 protein | 0.0114 | 0.3306 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.2165 | 0.5376 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 0.0887 | 0.0245 |
Brugia malayi | Hypothetical zinc metalloproteinase T16A9.4 | 0.0114 | 0.3306 | 0.8208 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.3306 | 0.8208 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0047 | 0.0756 | 0.0756 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0054 | 0.1007 | 0.1007 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.1101 | 0.2733 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0133 | 0.4028 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0051 | 0.0887 | 0.2201 |
Brugia malayi | MH2 domain containing protein | 0.0133 | 0.4028 | 1 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0084 | 0.2165 | 0.5376 |
Onchocerca volvulus | 0.0056 | 0.1101 | 1 | |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0054 | 0.1007 | 0.0471 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0076 | 0.0076 |
Echinococcus granulosus | expressed conserved protein | 0.0049 | 0.0819 | 0.0118 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0058 | 0.1141 | 0.1141 |
Schistosoma mansoni | family M13 non-peptidase homologue (M13 family) | 0.0058 | 0.1141 | 0.1141 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0819 | 0.2032 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0076 | 0.0076 |
Loa Loa (eye worm) | MBCTL1 | 0.0054 | 0.1007 | 0.2501 |
Brugia malayi | Peptidase family M13 containing protein | 0.0114 | 0.3306 | 0.8208 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.2165 | 0.5376 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0076 | 0.0076 |
Schistosoma mansoni | neprilysin-2 (M13 family) | 0.0058 | 0.1141 | 0.1141 |
Brugia malayi | mbt repeat family protein | 0.0047 | 0.0756 | 0.1876 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0058 | 0.1141 | 0.1141 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0114 | 0.3306 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.3306 | 0.8208 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0047 | 0.0756 | 0.1876 |
Brugia malayi | mbt repeat family protein | 0.0047 | 0.0756 | 0.1876 |
Brugia malayi | hypothetical protein | 0.0049 | 0.0819 | 0.2032 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0054 | 0.1007 | 0.0471 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0756 | 0.1876 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0114 | 0.3306 | 0.3306 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0076 | 0.0076 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0887 | 0.0887 |
Echinococcus granulosus | endothelin converting enzyme 1 | 0.0114 | 0.3306 | 0.4765 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.2241 | 0.5565 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0887 | 0.0887 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.2241 | 0.5565 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0047 | 0.0756 | 0.0756 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0054 | 0.1007 | 0.0471 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.003 | 0.0076 | 0.0076 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 0.0887 | 0.0245 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.2241 | 0.5565 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.2165 | 0.5376 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.2241 | 0.5565 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0054 | 0.1007 | 0.0471 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0819 | 0.2032 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1007 | 0.2501 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0187 | 0.6108 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.