TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 280.215 | Formula: C9H17N2O6P
H donors: 4 H acceptors: 6 LogP: -2.43 Rotable bonds: 9
Rule of 5 violations (Lipinski): 1
SMILES: O=C(C1CC1)NCC(=O)N(CCCP(=O)(O)O)O
InChi: 1S/C9H17N2O6P/c12-8(6-10-9(13)7-2-3-7)11(14)4-1-5-18(15,16)17/h7,14H,1-6H2,(H,10,13)(H2,15,16,17)
InChiKey: UHCOSYOZVSEXPK-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Escherichia coli	1-deoxy-D-xylulose 5-phosphate reductoisomerase	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Mycobacterium ulcerans	1-deoxy-D-xylulose 5-phosphate reductoisomerase	Get druggable targets OG5_130462	All targets in OG5_130462
Mycobacterium tuberculosis	Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras	Get druggable targets OG5_130462	All targets in OG5_130462
Wolbachia endosymbiont of Brugia malayi	1-deoxy-D-xylulose 5-phosphate reductoisomerase	Get druggable targets OG5_130462	All targets in OG5_130462
Mycobacterium leprae	PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS	Get druggable targets OG5_130462	All targets in OG5_130462
Plasmodium yoelii	1-deoxy-D-xylulose 5-phosphate reductoisomerase	Get druggable targets OG5_130462	All targets in OG5_130462
Toxoplasma gondii	1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative	Get druggable targets OG5_130462	All targets in OG5_130462
Chlamydia trachomatis	1-deoxy-D-xylulose 5-phosphate reductoisomerase	Get druggable targets OG5_130462	All targets in OG5_130462
Treponema pallidum	1-deoxy-D-xylulose 5-phosphate reductoisomerase	Get druggable targets OG5_130462	All targets in OG5_130462
Neospora caninum	1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative	Get druggable targets OG5_130462	All targets in OG5_130462
Plasmodium berghei	1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative	Get druggable targets OG5_130462	All targets in OG5_130462
Plasmodium knowlesi	1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative	Get druggable targets OG5_130462	All targets in OG5_130462
Plasmodium vivax	1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative	Get druggable targets OG5_130462	All targets in OG5_130462
Theileria parva	1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative	Get druggable targets OG5_130462	All targets in OG5_130462
Plasmodium falciparum	1-deoxy-D-xylulose 5-phosphate reductoisomerase	Get druggable targets OG5_130462	All targets in OG5_130462
Babesia bovis	1-deoxy-D-xylulose 5-phosphate reductoisomerase family protein	Get druggable targets OG5_130462	All targets in OG5_130462

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	tar DNA-binding protein	0.0124	0.0874	0.0862
Loa Loa (eye worm)	hypothetical protein	0.003	0.0142	0.0304
Leishmania major	fk506-binding protein 1-like protein	0.0033	0.0165	0.1637
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0194	0.1422	0.141
Brugia malayi	ecdysteroid receptor	0.0087	0.0582	0.1147
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0087	0.0582	0.1147
Echinococcus granulosus	peptidyl prolyl cis trans isomerase FKBP1A	0.0033	0.0165	0.0275
Brugia malayi	RNA recognition motif domain containing protein	0.0124	0.0874	0.178
Leishmania major	GTP-binding protein, putative	0.0023	0.0087	0.0481
Brugia malayi	MH2 domain containing protein	0.0118	0.083	0.1686
Trypanosoma brucei	apurinic/apyrimidinic endonuclease, putative	0.0019	0.006	0.0819
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Brugia malayi	hypothetical protein	0.0041	0.0226	0.0374
Echinococcus granulosus	Nuclear hormone receptor HR96	0.0041	0.0226	0.0385
Trichomonas vaginalis	phosphofructokinase, putative	0.0029	0.0131	0.1788
Echinococcus multilocularis	6 phosphofructokinase	0.0106	0.0732	0.1298
Schistosoma mansoni	ran	0.0023	0.0087	0.0074
Loa Loa (eye worm)	FKBP-type peptidyl-prolyl cis-trans isomerase-12	0.0033	0.0165	0.0354
Schistosoma mansoni	nuclear receptor	0.0041	0.0226	0.0214
Entamoeba histolytica	peptidyl-prolyl cis-trans isomerase, FKBP-type , putative	0.0033	0.0165	0.1637
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0087	0.0582	0.1147
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0087	0.0582	0.1147
Giardia lamblia	Endonuclease/Exonuclease/phosphatase	0.0019	0.006	0.0524
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0087	0.0582	0.057
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0041	0.0226	0.0385
Loa Loa (eye worm)	GTP-binding nuclear protein RAN/TC4	0.0023	0.0087	0.0186
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.007	0.0454	0.0796
Mycobacterium tuberculosis	Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase)	0.0106	0.0732	0.818
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0226	0.0486
Echinococcus multilocularis	transcription factor Dp 1	0.0038	0.0204	0.0344
Toxoplasma gondii	1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative	0.052	0.3955	1
Entamoeba histolytica	hypothetical protein	0.007	0.0454	0.5898
Trichomonas vaginalis	phosphofructokinase, putative	0.0106	0.0732	1
Loa Loa (eye worm)	nuclear receptor NHR-67	0.0041	0.0226	0.0486
Echinococcus multilocularis	peptidyl prolyl cis trans isomerase FKBP4	0.0033	0.0165	0.0275
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0198	0.1449	0.2594
Schistosoma mansoni	hypothetical protein	0.0032	0.016	0.0148
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0268	0.1994	0.4212
Trypanosoma cruzi	peptidyl-prolyl cis-trans isomerase, putative	0.0033	0.0165	0.1637
Trichomonas vaginalis	phosphofructokinase, putative	0.0106	0.0732	1
Onchocerca volvulus	Protein ultraspiracle homolog	0.0087	0.0582	0.4261
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0087	0.0582	0.1028
Trichomonas vaginalis	ap endonuclease, putative	0.0019	0.006	0.0819
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	0.0019	0.006	0.0085
Brugia malayi	Nuclear hormone receptor E75	0.0041	0.0226	0.0374
Mycobacterium ulcerans	6-phosphofructokinase	0.0106	0.0732	0.1726
Trichomonas vaginalis	importin beta-1, putative	0.0025	0.0105	0.1433
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0087	0.0582	0.125
Schistosoma mansoni	hypothetical protein	0.0423	0.3205	0.3196
Schistosoma mansoni	hypothetical protein	0.0032	0.016	0.0148
Entamoeba histolytica	phosphofructokinase, putative	0.0106	0.0732	1
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0087	0.0582	0.1028
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0087	0.0582	0.1028
Schistosoma mansoni	hypothetical protein	0.0332	0.2496	0.2486
Entamoeba histolytica	peptidyl-prolyl cis-trans isomerase, FKBP-type, putative	0.0033	0.0165	0.1637
Echinococcus granulosus	nuclear receptor nhr 48	0.0041	0.0226	0.0385
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.0041	0.0226	0.0385
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0087	0.0582	0.1147
Echinococcus granulosus	tyrosyl DNA phosphodiesterase 1	0.0065	0.0418	0.0732
Loa Loa (eye worm)	hypothetical protein	0.0268	0.1994	0.4279
Brugia malayi	latrophilin 2 splice variant baaae	0.007	0.0453	0.0866
Loa Loa (eye worm)	nuclear hormone receptor-like 1	0.0046	0.0264	0.0568
Entamoeba histolytica	hypothetical protein	0.0025	0.0105	0.0749
Plasmodium falciparum	peptidyl-prolyl cis-trans isomerase FKBP35	0.0033	0.0165	0.027
Echinococcus multilocularis	peptidyl prolyl cis trans isomerase FKBP4	0.0028	0.013	0.0211
Schistosoma mansoni	immunophilin	0.0028	0.013	0.0117
Brugia malayi	CXXC zinc finger family protein	0.003	0.014	0.0186
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Brugia malayi	hypothetical protein	0.0163	0.1178	0.2441
Entamoeba histolytica	hypothetical protein	0.0026	0.0109	0.0803
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Schistosoma mansoni	cpg binding protein	0.0031	0.0153	0.014
Echinococcus granulosus	cpg binding protein	0.0031	0.0153	0.0253
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0087	0.0582	0.1147
Treponema pallidum	1-deoxy-D-xylulose 5-phosphate reductoisomerase	0.052	0.3955	1
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0087	0.0582	0.1147
Trichomonas vaginalis	6-phosphofructokinase, putative	0.0029	0.0131	0.1788
Echinococcus granulosus	serine protein kinase ATM	0.0026	0.0109	0.0173
Echinococcus granulosus	GTP binding nuclear protein Ran	0.0023	0.0087	0.0133
Loa Loa (eye worm)	nuclear receptor nhr-7B	0.0041	0.0226	0.0486
Echinococcus multilocularis	serine protein kinase ATM	0.0026	0.0109	0.0173
Echinococcus multilocularis	importin subunit beta 1	0.0031	0.0151	0.0249
Echinococcus multilocularis	e3 ubiquitin protein ligase siah1	0.061	0.466	0.839
Schistosoma mansoni	hypothetical protein	0.0725	0.5551	0.5545
Schistosoma mansoni	nuclear receptor	0.0041	0.0226	0.0214
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Brugia malayi	exodeoxyribonuclease III family protein	0.0019	0.006	0.0013
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0194	0.1422	0.2543
Schistosoma mansoni	ap endonuclease	0.0019	0.006	0.0047
Brugia malayi	phosphofructokinase	0.0106	0.0732	0.1472
Trichomonas vaginalis	phosphofructokinase, putative	0.0029	0.0131	0.1788
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0087	0.0582	0.1028
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.0025	0.0105	0.1433
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0087	0.0582	0.1028
Treponema pallidum	peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB)	0.0033	0.0165	0.027
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Loa Loa (eye worm)	hypothetical protein	0.007	0.0453	0.0972
Plasmodium vivax	ataxin-2 like protein, putative	0.003	0.0142	0.021
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease	0.0019	0.006	0.0086
Leishmania major	importin beta-1 subunit, putative	0.0025	0.0105	0.0749
Loa Loa (eye worm)	MH2 domain-containing protein	0.0118	0.083	0.1782
Toxoplasma gondii	target of rapamycin (TOR), putative	0.0019	0.0054	0.0137
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0087	0.0582	0.1147
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0087	0.0582	0.125
Brugia malayi	6-phosphofructokinase	0.0106	0.0732	0.1472
Plasmodium falciparum	ataxin-2 like protein, putative	0.003	0.0142	0.021
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0582	0.125
Schistosoma mansoni	nuclear receptor nhr-48	0.0041	0.0226	0.0214
Brugia malayi	nuclear receptor NHR-88	0.0087	0.0582	0.1147
Schistosoma mansoni	ap endonuclease	0.0019	0.006	0.0047
Treponema pallidum	diphosphate--fructose-6-phosphate 1-phosphotransferase	0.0029	0.0131	0.0182
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Schistosoma mansoni	transcription factor LCR-F1	0.007	0.0454	0.0442
Echinococcus multilocularis	FKBP12 rapamycin complex associated protein	0.0019	0.0054	0.0074
Echinococcus multilocularis	ecdysone induced protein 78C	0.0087	0.0582	0.1028
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0032	0.016	0.0231
Trypanosoma cruzi	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.0065	0.0418	0.537
Brugia malayi	Tyrosyl-DNA phosphodiesterase family protein	0.0065	0.0418	0.079
Schistosoma mansoni	ran	0.0023	0.0087	0.0074
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0194	0.1422	0.2543
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Trichomonas vaginalis	ran, putative	0.0023	0.0087	0.1185
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0194	0.1422	0.2543
Schistosoma mansoni	phosphatidylinositol 3-and 4-kinase	0.0019	0.0054	0.0041
Loa Loa (eye worm)	phosphatidylinositol 3	0.0019	0.0054	0.0116
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0226	0.0486
Trypanosoma brucei	phosphatidylinositol 3-kinase, putative	0.0019	0.0054	0.074
Schistosoma mansoni	hypothetical protein	0.007	0.0454	0.0442
Entamoeba histolytica	hypothetical protein	0.007	0.0454	0.5898
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0046	0.0264	0.0252
Loa Loa (eye worm)	6-phosphofructokinase	0.0106	0.0732	0.1571
Trichomonas vaginalis	phosphofructokinase, putative	0.0029	0.0131	0.1788
Loa Loa (eye worm)	phosphatidylinositol 3	0.0019	0.0054	0.0116
Schistosoma mansoni	ubiquitin ligase sina (ec 6.3.2.-) (seven in absentia homolog)(smsina)	0.061	0.466	0.4653
Schistosoma mansoni	thyroid hormone receptor	0.0087	0.0582	0.057
Giardia lamblia	FKBP-type peptidyl-prolyl cis-trans isomerase	0.0033	0.0165	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Trichomonas vaginalis	peptidylprolyl isomerase, putative	0.0033	0.0165	0.2256
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0063	0.0399	0.0387
Trichomonas vaginalis	phosphofructokinase, putative	0.0029	0.0131	0.1788
Plasmodium vivax	6-phosphofructokinase, putative	0.0029	0.0131	0.0182
Echinococcus granulosus	FKBP12 rapamycin complex associated protein	0.0019	0.0054	0.0074
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0226	0.0486
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0226	0.0486
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0087	0.0582	0.1028
Plasmodium vivax	importin-beta 2, putative	0.0031	0.0151	0.0233
Plasmodium falciparum	1-deoxy-D-xylulose 5-phosphate reductoisomerase	0.052	0.3955	1
Loa Loa (eye worm)	hypothetical protein	0.0046	0.0264	0.0568
Brugia malayi	hypothetical protein	0.007	0.0454	0.0868
Trypanosoma brucei	importin beta-1 subunit, putative	0.0031	0.0151	0.2059
Loa Loa (eye worm)	hypothetical protein	0.0046	0.0264	0.0568
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0226	0.0486
Trypanosoma brucei	GTP-binding nuclear protein rtb2, putative	0.0023	0.0087	0.1185
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0226	0.0486
Plasmodium falciparum	importin beta, putative	0.0031	0.0151	0.0233
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0582	0.125
Loa Loa (eye worm)	FKBP5 protein	0.0033	0.0165	0.0354
Trypanosoma cruzi	PAB1-binding protein , putative	0.003	0.0142	0.1291
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0087	0.0582	0.4261
Leishmania major	hypothetical protein, conserved	0.003	0.0142	0.1291
Schistosoma mansoni	ataxia telangiectasia mutated (atm)-related	0.0019	0.0054	0.0041
Echinococcus granulosus	ecdysone induced protein 78C	0.0087	0.0582	0.1028
Echinococcus granulosus	thyroid hormone receptor alpha	0.0041	0.0226	0.0385
Plasmodium vivax	6-phosphofructokinase, putative	0.0029	0.0131	0.0182
Brugia malayi	Nuclear hormone receptor E75	0.0041	0.0226	0.0374
Brugia malayi	hypothetical protein	0.0019	0.0059	0.001
Entamoeba histolytica	hypothetical protein	0.007	0.0454	0.5898
Leishmania major	peptidylprolyl isomerase-like protein	0.0033	0.0165	0.1637
Loa Loa (eye worm)	hypothetical protein	0.0046	0.0264	0.0568
Schistosoma mansoni	ataxia telangiectasia mutated (atm)	0.0026	0.0109	0.0096
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.0041	0.0226	0.0832
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0102	0.0705	0.1513
Trichomonas vaginalis	ap endonuclease, putative	0.0019	0.006	0.0819
Echinococcus multilocularis	tyrosyl DNA phosphodiesterase 1	0.0065	0.0418	0.0732
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Toxoplasma gondii	FATC domain-containing protein	0.0026	0.0109	0.0275
Trypanosoma brucei	ATP-dependent 6-phosphofructokinase, glycosomal	0.0106	0.0732	1
Entamoeba histolytica	phosphofructokinase, putative	0.0106	0.0732	1
Schistosoma mansoni	immunophilin	0.0033	0.0165	0.0152
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0194	0.1422	0.141
Schistosoma mansoni	tar DNA-binding protein	0.0124	0.0874	0.0862
Echinococcus granulosus	peptidyl prolyl cis trans isomerase FKBP4	0.0028	0.013	0.0211
Mycobacterium ulcerans	1-deoxy-D-xylulose 5-phosphate reductoisomerase	0.052	0.3955	1
Trypanosoma brucei	phosphatidylinositol 4-kinase, putative	0.0019	0.0054	0.074
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0087	0.0582	0.1028
Schistosoma mansoni	immunophilin	0.0033	0.0165	0.0152
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0102	0.0705	0.1414
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0087	0.0582	0.1147
Echinococcus granulosus	snurportin 1	0.0332	0.2496	0.4483
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0194	0.1422	0.3051
Entamoeba histolytica	phosphofructokinase, putative	0.0106	0.0732	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0087	0.0582	0.125
Toxoplasma gondii	HEAT repeat-containing protein	0.0031	0.0151	0.0381
Schistosoma mansoni	nuclear hormone receptor	0.0041	0.0226	0.0214
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0087	0.0582	0.057
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0087	0.0582	0.057
Brugia malayi	nuclear receptor RXR	0.0041	0.0226	0.0374
Toxoplasma gondii	GTP-binding nuclear protein ran/tc4	0.0023	0.0087	0.0219
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Trypanosoma cruzi	PAB1-binding protein , putative	0.003	0.0142	0.1291
Echinococcus granulosus	importin subunit beta 1	0.0031	0.0151	0.0249
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0582	0.125
Brugia malayi	RNA, U transporter 1	0.0089	0.0598	0.118
Echinococcus granulosus	tar DNA binding protein	0.0124	0.0874	0.1554
Brugia malayi	tailless protein	0.0041	0.0226	0.0374
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0032	0.016	0.0266
Brugia malayi	Latrophilin receptor protein 2	0.0032	0.016	0.0231
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0226	0.0486
Brugia malayi	nuclear hormone receptor	0.0087	0.0582	0.1147
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0087	0.0582	0.057
Echinococcus multilocularis	phosphatidylinositol 3 and 4 kinase	0.0019	0.0054	0.0074
Entamoeba histolytica	tyrosyl-DNA phosphodiesterase, putative	0.0065	0.0418	0.537
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0087	0.0582	0.1028
Trichomonas vaginalis	fk506-binding protein, putative	0.0033	0.0165	0.2256
Trypanosoma brucei	PAB1-binding protein , putative	0.003	0.0142	0.1935
Brugia malayi	Importin beta-1 subunit	0.0031	0.0151	0.021
Brugia malayi	TAR-binding protein	0.0124	0.0874	0.178
Echinococcus granulosus	nuclear receptor subfamily 4 group A	0.0041	0.0226	0.0385
Trypanosoma brucei	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.0065	0.0418	0.5713
Schistosoma mansoni	nuclear hormone receptor	0.0087	0.0582	0.057
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0582	0.125
Brugia malayi	Ubiquitin ligase sia-1	0.061	0.466	1
Plasmodium vivax	1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative	0.052	0.3955	1
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0087	0.0582	0.125
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	0.0019	0.006	0.0086
Loa Loa (eye worm)	6-phosphofructokinase	0.0106	0.0732	0.1571
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Leishmania major	tyrosyl-DNA phosphodiesterase 1	0.0065	0.0418	0.537
Brugia malayi	Nuclear hormone receptor-like 1	0.0046	0.0264	0.0457
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0087	0.0582	0.1028
Brugia malayi	hypothetical protein	0.0046	0.0264	0.0457
Onchocerca volvulus		0.0041	0.0226	0.0832
Echinococcus multilocularis	GPCR, family 2	0.0032	0.016	0.0266
Brugia malayi	ecdysone receptor	0.0041	0.0226	0.0374
Loa Loa (eye worm)	hypothetical protein	0.0163	0.1178	0.2529
Echinococcus granulosus	nuclear receptor subfamily 1 group D	0.0046	0.0264	0.0454
Loa Loa (eye worm)	hypothetical protein	0.0032	0.016	0.0344
Toxoplasma gondii	6-phosphofructokinase	0.0029	0.0131	0.0331
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0582	0.125
Echinococcus granulosus	dnaJ subfamily B	0.0423	0.3205	0.5764
Onchocerca volvulus		0.0163	0.1178	1
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0087	0.0582	0.1028
Giardia lamblia	GTP-binding nuclear protein RAN/TC4	0.0023	0.0087	0.2937
Entamoeba histolytica	Ran family GTPase	0.0023	0.0087	0.0481
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Plasmodium falciparum	ATP-dependent 6-phosphofructokinase	0.0029	0.0131	0.0182
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.007	0.0454	0.0796
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0226	0.0486
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.0025	0.0105	0.1433
Trypanosoma cruzi	tyrosyl-DNA Phosphodiesterase (Tdp1), putative	0.0065	0.0418	0.537
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0087	0.0582	0.125
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0056	0.0347	0.0877
Leishmania major	apurinic/apyrimidinic endonuclease-redox protein	0.0019	0.006	0.0086
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.0041	0.0226	0.0832
Onchocerca volvulus	Bile acid receptor homolog	0.0087	0.0582	0.4261
Trypanosoma cruzi	ATP-dependent 6-phosphofructokinase, glycosomal	0.0106	0.0732	1
Mycobacterium tuberculosis	Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras	0.0125	0.0882	1
Echinococcus granulosus	Nuclear hormone receptor HR96	0.0041	0.0226	0.0385
Treponema pallidum	diphosphate--fructose-6-phosphate 1-phosphotransferase	0.0106	0.0732	0.1726
Schistosoma mansoni	hepatocyte nuclear factor 4-alpha (hnf-4-alpha)	0.0041	0.0226	0.0214
Entamoeba histolytica	pyrophosphate-dependent phosphofructokinase	0.0029	0.0131	0.1132
Brugia malayi	nuclear hormone receptor	0.0041	0.0226	0.0374
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0226	0.0486
Schistosoma mansoni	cpg binding protein	0.0031	0.0153	0.014
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0087	0.0582	0.125
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0087	0.0582	0.1028
Echinococcus multilocularis	snurportin 1	0.0332	0.2496	0.4483
Schistosoma mansoni	tyrosyl-DNA phosphodiesterase	0.0065	0.0418	0.0406
Brugia malayi	GTP-binding nuclear protein RAN/TC4	0.0023	0.0087	0.0071
Schistosoma mansoni	6-phosphofructokinase	0.0106	0.0732	0.072
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Brugia malayi	nuclear hormone receptor family member nhr-6	0.0041	0.0226	0.0374
Loa Loa (eye worm)	hypothetical protein	0.0046	0.0264	0.0568
Loa Loa (eye worm)	DR-78	0.0041	0.0226	0.0486
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0087	0.0582	0.1147
Trypanosoma brucei	phosphatidylinositol kinase related protein, putative	0.0026	0.0109	0.1484
Onchocerca volvulus		0.0041	0.0226	0.0832
Plasmodium vivax	70 kDa peptidylprolyl isomerase, putative	0.0033	0.0165	0.027
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0226	0.0486
Brugia malayi	nuclear hormone receptor family member odr-7	0.0041	0.0226	0.0374
Loa Loa (eye worm)	CXXC zinc finger family protein	0.003	0.014	0.03
Brugia malayi	nuclear receptor RXR	0.0046	0.0264	0.0457
Echinococcus granulosus	FTZ F1 alpha	0.0087	0.0582	0.1028
Schistosoma mansoni	hypothetical protein	0.0032	0.016	0.0148
Loa Loa (eye worm)	hypothetical protein	0.061	0.466	1
Brugia malayi	RNA binding protein	0.0124	0.0874	0.178
Plasmodium falciparum	ATP-dependent 6-phosphofructokinase	0.0029	0.0131	0.0182
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0226	0.0486
Loa Loa (eye worm)	steroid hormone receptor	0.0087	0.0582	0.125
Trypanosoma cruzi	peptidyl-prolyl cis-trans isomerase, putative	0.0033	0.0165	0.1637
Brugia malayi	FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59	0.0033	0.0165	0.0241
Echinococcus multilocularis	cpg binding protein	0.0031	0.0153	0.0253
Onchocerca volvulus		0.0087	0.0582	0.4261
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0198	0.1449	0.2594
Toxoplasma gondii	LsmAD domain-containing protein	0.003	0.0142	0.0358
Loa Loa (eye worm)	RNA binding protein	0.0124	0.0874	0.1875
Trypanosoma brucei	phosphatidylinositol 3-related kinase, putative	0.0019	0.0054	0.074
Entamoeba histolytica	hypothetical protein	0.007	0.0454	0.5898
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.0041	0.0226	0.0385
Echinococcus multilocularis	geminin	0.0725	0.5551	1
Leishmania major	ATP-dependent phosphofructokinase	0.0106	0.0732	1
Echinococcus multilocularis	nuclear receptor subfamily 1 group D	0.0046	0.0264	0.0454
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0087	0.0582	0.1147
Brugia malayi	Nuclear hormone receptor-like 1	0.0046	0.0264	0.0457
Trypanosoma brucei	target of rapamycin kinase 3, putative	0.0019	0.0054	0.074
Toxoplasma gondii	exonuclease III APE	0.0019	0.006	0.0152
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0087	0.0582	0.1147
Plasmodium vivax	GTP-binding nuclear protein RAN/TC4, putative	0.0023	0.0087	0.0069
Schistosoma mansoni	tar DNA-binding protein	0.0124	0.0874	0.0862
Trypanosoma brucei	Phosphatidylinositol 3-kinase tor1	0.0019	0.0054	0.074
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0226	0.0486
Echinococcus multilocularis	fk506 binding protein	0.0033	0.0165	0.0275
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0087	0.0582	0.057
Echinococcus granulosus	transcription factor Dp 1	0.0038	0.0204	0.0344
Schistosoma mansoni	coup transcription factor	0.0087	0.0582	0.057
Trypanosoma brucei	peptidyl-prolyl cis-trans isomerase, putative	0.0033	0.0165	0.2256
Brugia malayi	Nuclear hormone receptor-like 1	0.0087	0.0582	0.1147
Loa Loa (eye worm)	nucleolar RNA-associated protein alpha	0.0332	0.2496	0.5356
Trypanosoma cruzi	phosphatidylinositol kinase related protein, putative	0.0019	0.0054	0.0004
Schistosoma mansoni	zinc finger protein	0.0041	0.0226	0.0214
Brugia malayi	Steroid receptor seven-up type 2	0.0087	0.0582	0.1147
Brugia malayi	steroid hormone receptor	0.0087	0.0582	0.1147
Loa Loa (eye worm)	hypothetical protein	0.0022	0.0081	0.0173
Trypanosoma brucei	FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative	0.0033	0.0165	0.2256
Echinococcus multilocularis	retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha	0.0041	0.0226	0.0385
Loa Loa (eye worm)	nuclear hormone receptor	0.0041	0.0226	0.0486
Brugia malayi	hypothetical protein	0.003	0.0142	0.019
Echinococcus multilocularis	FTZ F1 alpha	0.0087	0.0582	0.1028
Brugia malayi	photoreceptor-specific nuclear receptor	0.0087	0.0582	0.1147
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0087	0.0582	0.057
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0087	0.0582	0.1028
Schistosoma mansoni	thyroid hormone receptor	0.0087	0.0582	0.057
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0194	0.1422	0.141
Entamoeba histolytica	exodeoxyribonuclease III, putative	0.0019	0.006	0.0086
Wolbachia endosymbiont of Brugia malayi	1-deoxy-D-xylulose 5-phosphate reductoisomerase	0.052	0.3955	1
Trichomonas vaginalis	phosphofructokinase, putative	0.0029	0.0131	0.1788
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	0.0019	0.006	0.0129
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0124	0.0874	0.1875
Giardia lamblia	Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit	0.0029	0.0131	0.6916
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0226	0.0486
Trichomonas vaginalis	phosphofructokinase, putative	0.0106	0.0732	1
Echinococcus multilocularis	nuclear receptor nhr 48	0.0041	0.0226	0.0385
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0582	0.125
Plasmodium falciparum	GTP-binding nuclear protein RAN/TC4	0.0023	0.0087	0.0069
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Echinococcus granulosus	6 phosphofructokinase	0.0106	0.0732	0.1298
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Trichomonas vaginalis	phosphofructokinase, putative	0.0029	0.0131	0.1788
Leishmania major	phosphatidylinositol kinase related protein, putative	0.0019	0.0054	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0582	0.125
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Brugia malayi	nuclear receptor subfamily 1, group D, member 1, putative	0.0041	0.0226	0.0374
Schistosoma mansoni	hypothetical protein	0.0032	0.016	0.0148
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0582	0.125
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0026	0.0109	0.1484
Echinococcus multilocularis	nuclear receptor subfamily 4 group A	0.0041	0.0226	0.0385
Brugia malayi	orphan nuclear receptor NR2E1	0.0041	0.0226	0.0374
Schistosoma mansoni	cpg binding protein	0.003	0.014	0.0127
Brugia malayi	conserved hypotetical protein	0.0041	0.0226	0.0374
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Trypanosoma brucei	importin beta-1 subunit, putative	0.0031	0.0151	0.2059
Schistosoma mansoni	immunophilin FK506 binding protein FKBP12	0.0033	0.0165	0.0152
Schistosoma mansoni	tar DNA-binding protein	0.0124	0.0874	0.0862
Giardia lamblia	70 kDa peptidylprolyl isomerase, putative	0.0033	0.0165	1
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0194	0.1422	0.2969
Trypanosoma cruzi	phosphatidylinositol kinase related protein, putative	0.0022	0.0081	0.0389
Trypanosoma cruzi	FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative	0.0033	0.0165	0.1637
Mycobacterium ulcerans	FK-506 binding protein, peptidyl-prolyl cis-trans isomerase	0.0033	0.0165	0.027
Brugia malayi	6-phosphofructokinase	0.0106	0.0732	0.1472
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Brugia malayi	FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12	0.0033	0.0165	0.0241
Trypanosoma cruzi	importin beta-1 subunit, putative	0.0025	0.0105	0.0749
Toxoplasma gondii	phosphofructokinase domain-containing protein	0.0029	0.0131	0.0331
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0194	0.1422	0.2543
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0041	0.0226	0.0385
Schistosoma mansoni	hypothetical protein	0.0725	0.5551	0.5545
Trichomonas vaginalis	peptidylprolyl isomerase, putative	0.0033	0.0165	0.2256
Echinococcus multilocularis	GTP binding nuclear protein Ran	0.0023	0.0087	0.0133
Loa Loa (eye worm)	hypothetical protein	0.0046	0.0264	0.0568
Loa Loa (eye worm)	transcription factor SMAD2	0.0118	0.083	0.1782
Schistosoma mansoni	tar DNA-binding protein	0.0124	0.0874	0.0862
Schistosoma mansoni	RAR-like nuclear receptor	0.0087	0.0582	0.057
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0087	0.0582	0.1028
Echinococcus multilocularis	dnaJ subfamily B	0.0423	0.3205	0.5764
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0087	0.0582	0.1028
Loa Loa (eye worm)	TAR-binding protein	0.0124	0.0874	0.1875
Trypanosoma cruzi	FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative	0.0033	0.0165	0.1637
Mycobacterium leprae	PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS	0.052	0.3955	1
Schistosoma mansoni	importin beta-1	0.0031	0.0151	0.0138
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0087	0.0582	0.1147
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0087	0.0582	0.057
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0087	0.0582	0.1147
Schistosoma mansoni	retinoic acid receptor RXR	0.0087	0.0582	0.057
Loa Loa (eye worm)	hypothetical protein	0.0028	0.013	0.0279
Trypanosoma cruzi	GTP-binding nuclear protein rtb2, putative	0.0023	0.0087	0.0481
Schistosoma mansoni	hypothetical protein	0.007	0.0453	0.0441
Plasmodium falciparum	ataxin-2 like protein, putative	0.003	0.0142	0.021
Echinococcus granulosus	GPCR family 2	0.0032	0.016	0.0266
Schistosoma mansoni	6-phosphofructokinase	0.0106	0.0732	0.072
Trichomonas vaginalis	phosphofructokinase, putative	0.0106	0.0732	1
Echinococcus granulosus	peptidyl prolyl cis trans isomerase FKBP4	0.0033	0.0165	0.0275
Trichomonas vaginalis	immunophilin, putative	0.0033	0.0165	0.2256
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0032	0.016	0.0344
Trypanosoma cruzi	GTP-binding nuclear protein rtb2, putative	0.0023	0.0087	0.0481
Echinococcus multilocularis	tar DNA binding protein	0.0124	0.0874	0.1554
Echinococcus granulosus	geminin	0.0725	0.5551	1
Loa Loa (eye worm)	phosphofructokinase	0.0106	0.0732	0.1571
Brugia malayi	hypothetical protein	0.0041	0.0226	0.0374
Echinococcus granulosus	phosphatidylinositol 3 and 4 kinase	0.0019	0.0054	0.0074
Brugia malayi	hypothetical protein	0.0046	0.0264	0.0457
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0087	0.0582	0.125
Brugia malayi	nuclear receptor NHR-88	0.0041	0.0226	0.0374
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0019	0.0054	0.074
Trypanosoma cruzi	phosphatidylinositol kinase related protein, putative	0.0026	0.0109	0.0803
Echinococcus granulosus	e3 ubiquitin protein ligase siah1	0.061	0.466	0.839
Toxoplasma gondii	phosphofructokinase PFKII	0.0029	0.0131	0.0331
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0032	0.016	0.0266
Loa Loa (eye worm)	tyrosyl-DNA phosphodiesterase	0.0065	0.0418	0.0898
Schistosoma mansoni	ecdysone-induced protein 78c (dr-78)	0.0046	0.0264	0.0252
Schistosoma mansoni	nuclear hormone receptor	0.0041	0.0226	0.0214
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0026	0.0109	0.0118
Chlamydia trachomatis	1-deoxy-D-xylulose 5-phosphate reductoisomerase	0.052	0.3955	1
Brugia malayi	nuclear receptor NHR-67	0.0041	0.0226	0.0374
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	0.0019	0.006	0.0085
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0151	0.0324

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= -5.15	Inhibitory concentration against DOXP reductoisomerase	ChEMBL.	15887963
IC50 (binding)	> 200 uM	Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPH	ChEMBL.	23819803

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL607355

Bibliographic References

2 literature references were collected for this gene.

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Detailed information for compound 1132090