Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.003 | 0.0106 | 0.0763 |
Trichomonas vaginalis | Clan MA, family M8, leishmanolysin-like metallopeptidase | 0.0042 | 0.0234 | 0.0995 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.011 | 0.0409 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0196 | 0.1889 | 0.1889 |
Schistosoma mansoni | ets-related | 0.0235 | 0.231 | 0.8454 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.021 | 0.2041 | 0.7615 |
Plasmodium falciparum | glutathione reductase | 0.003 | 0.0106 | 0.1492 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0808 | 0.3016 |
Echinococcus multilocularis | exocyst complex component 2 | 0.0042 | 0.0234 | 0.0873 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0149 | 0.1385 | 0.5168 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0149 | 0.1385 | 0.5888 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.003 | 0.0106 | 0.0763 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0234 | 0.2295 | 0.8565 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0808 | 0.3016 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0234 | 0.0873 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.1347 | 0.5029 |
Brugia malayi | Probable exocyst complex component Sec5 | 0.0042 | 0.0234 | 0.0873 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0234 | 0.0995 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.003 | 0.0106 | 0.0763 |
Brugia malayi | Thioredoxin reductase | 0.0086 | 0.0708 | 0.2643 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0097 | 0.0826 | 0.3025 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0196 | 0.1889 | 0.1889 |
Loa Loa (eye worm) | glutathione reductase | 0.0086 | 0.0708 | 0.2643 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0053 | 0.0354 | 1 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0086 | 0.0708 | 0.5113 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0149 | 0.1385 | 0.5888 |
Loa Loa (eye worm) | beta-lactamase | 0.0149 | 0.1385 | 0.5168 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.1347 | 0.5029 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.003 | 0.0106 | 0.0763 |
Onchocerca volvulus | Huntingtin homolog | 0.0127 | 0.1147 | 0.4625 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0196 | 0.1889 | 0.1889 |
Schistosoma mansoni | semaphorin 5-related | 0.0095 | 0.0808 | 0.2958 |
Brugia malayi | Sema domain containing protein | 0.0095 | 0.0808 | 0.3016 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0149 | 0.1385 | 0.5888 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.003 | 0.0106 | 0.0763 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.121 | 0.4515 |
Echinococcus multilocularis | plexin a4 | 0.0269 | 0.268 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0149 | 0.1385 | 0.1385 |
Brugia malayi | beta-lactamase | 0.0149 | 0.1385 | 0.5168 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.1385 | 0.5168 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0234 | 0.0873 |
Onchocerca volvulus | 0.0149 | 0.1385 | 0.5687 | |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0234 | 0.0873 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.003 | 0.0106 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0149 | 0.1385 | 0.5168 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0149 | 0.1385 | 0.5168 |
Loa Loa (eye worm) | fli-1 protein | 0.0235 | 0.231 | 0.8619 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.003 | 0.0106 | 0.0763 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.003 | 0.0106 | 0.0394 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.003 | 0.0106 | 0.0763 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.0808 | 0.2958 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0234 | 0.0873 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0077 | 0.0617 | 0.2304 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.003 | 0.0106 | 0.1492 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0149 | 0.1385 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.0467 | 0.3369 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0097 | 0.0826 | 0.3084 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0808 | 0.3016 |
Loa Loa (eye worm) | hypothetical protein | 0.0228 | 0.2232 | 0.8329 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.003 | 0.0106 | 0.1492 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0086 | 0.0708 | 0.5113 |
Loa Loa (eye worm) | sema domain-containing protein | 0.0095 | 0.0808 | 0.3016 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0234 | 0.6615 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.003 | 0.0106 | 0.0763 |
Brugia malayi | Fli-1 protein | 0.0235 | 0.231 | 0.8619 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0149 | 0.1385 | 0.1385 |
Brugia malayi | plexin A | 0.0269 | 0.268 | 1 |
Echinococcus granulosus | plexin a4 | 0.0269 | 0.268 | 1 |
Trichomonas vaginalis | Clan MA, family M8, leishmanolysin-like metallopeptidase | 0.0042 | 0.0234 | 0.0995 |
Plasmodium vivax | hypothetical protein, conserved | 0.0149 | 0.1385 | 1 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0063 | 0.0467 | 0.0467 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.011 | 0.0791 |
Echinococcus multilocularis | semaphorin 5B | 0.0095 | 0.0808 | 0.3016 |
Loa Loa (eye worm) | plexin A | 0.0269 | 0.268 | 1 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.003 | 0.0106 | 0.0763 |
Mycobacterium ulcerans | lipase LipD | 0.0149 | 0.1385 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0127 | 0.1147 | 0.4625 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0097 | 0.0826 | 0.3084 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0149 | 0.1385 | 0.5168 |
Echinococcus multilocularis | transcription factor collier | 0.0042 | 0.0234 | 0.0873 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0077 | 0.0617 | 0.2304 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0145 | 0.1347 | 0.5029 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0149 | 0.1385 | 0.1385 |
Onchocerca volvulus | 0.0149 | 0.1385 | 0.5687 | |
Echinococcus granulosus | transcription factor collier | 0.0042 | 0.0234 | 0.0873 |
Entamoeba histolytica | tyrosin kinase, putative | 0.0053 | 0.0354 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.011 | 0.0409 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0234 | 0.6615 |
Brugia malayi | hypothetical protein | 0.0095 | 0.0808 | 0.3016 |
Echinococcus granulosus | exocyst complex component 2 | 0.0042 | 0.0234 | 0.0873 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.0467 | 0.3369 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0808 | 0.3016 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.011 | 0.0401 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0063 | 0.0467 | 0.1741 |
Onchocerca volvulus | 0.0239 | 0.2352 | 1 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0234 | 0.0995 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.1385 | 0.5168 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0063 | 0.0467 | 0.1741 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.011 | 0.0401 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0234 | 0.0856 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.003 | 0.0106 | 0.0763 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0234 | 0.0995 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.1147 | 0.4279 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0149 | 0.1385 | 0.1385 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.011 | 0.0409 |
Echinococcus granulosus | muscleblind protein | 0.0145 | 0.1347 | 0.5029 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0149 | 0.1385 | 1 |
Onchocerca volvulus | 0.0228 | 0.2232 | 0.9464 | |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0098 | 0.0364 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0196 | 0.1889 | 0.1889 |
Trichomonas vaginalis | Clan MA, family M8, leishmanolysin-like metallopeptidase | 0.0042 | 0.0234 | 0.0995 |
Toxoplasma gondii | ABC1 family protein | 0.0149 | 0.1385 | 1 |
Brugia malayi | hypothetical protein | 0.0095 | 0.0808 | 0.3016 |
Trichomonas vaginalis | esterase, putative | 0.0149 | 0.1385 | 0.5888 |
Onchocerca volvulus | 0.0149 | 0.1385 | 0.5687 | |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.003 | 0.0106 | 0.0763 |
Echinococcus granulosus | semaphorin 1A | 0.0095 | 0.0808 | 0.3016 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0497 | 0.1854 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.003 | 0.0106 | 0.0763 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0149 | 0.1385 | 0.5888 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.003 | 0.0106 | 0.0763 |
Plasmodium falciparum | glutathione reductase | 0.0086 | 0.0708 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0808 | 0.3016 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.1385 | 0.5168 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.0234 | 0.0856 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.1147 | 0.4279 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.011 | 0.0791 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.011 | 0.0401 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.003 | 0.0106 | 0.0763 |
Mycobacterium ulcerans | hypothetical protein | 0.0149 | 0.1385 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0097 | 0.0826 | 0.3084 |
Trichomonas vaginalis | glutathione reductase, putative | 0.003 | 0.0106 | 0.0449 |
Loa Loa (eye worm) | sema domain-containing protein | 0.0095 | 0.0808 | 0.3016 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0097 | 0.0826 | 0.3084 |
Brugia malayi | Plexin repeat family protein | 0.0228 | 0.2232 | 0.8329 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0077 | 0.0617 | 0.2304 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.003 | 0.0106 | 0.0106 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0063 | 0.0467 | 0.3369 |
Entamoeba histolytica | cell surface protease gp63, putative | 0.0042 | 0.0234 | 0.6615 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.003 | 0.0106 | 0.0387 |
Echinococcus multilocularis | hypothetical protein | 0.0095 | 0.0808 | 0.3016 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.0467 | 0.3369 |
Brugia malayi | Sema domain containing protein | 0.0095 | 0.0808 | 0.3016 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0097 | 0.0826 | 0.3025 |
Leishmania major | trypanothione reductase | 0.0086 | 0.0708 | 0.5113 |
Onchocerca volvulus | 0.0095 | 0.0808 | 0.3115 | |
Schistosoma mansoni | plexin | 0.0133 | 0.121 | 0.4429 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0234 | 0.6615 |
Treponema pallidum | NADH oxidase | 0.003 | 0.0106 | 1 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.003 | 0.0106 | 0.0394 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0218 | 0.2124 | 0.2124 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.011 | 0.0409 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.0467 | 0.1708 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.1385 | 0.5168 |
Echinococcus granulosus | semaphorin 5B | 0.0095 | 0.0808 | 0.3016 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0097 | 0.0826 | 0.3084 |
Plasmodium vivax | glutathione reductase, putative | 0.0086 | 0.0708 | 0.5113 |
Mycobacterium tuberculosis | Probable reductase | 0.0196 | 0.1889 | 0.1889 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0097 | 0.0826 | 0.3025 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0097 | 0.0826 | 0.3084 |
Mycobacterium tuberculosis | Conserved protein | 0.0149 | 0.1385 | 0.1385 |
Toxoplasma gondii | thioredoxin reductase | 0.0086 | 0.0708 | 0.5113 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0063 | 0.0467 | 0.3369 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.003 | 0.0106 | 0.0763 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0218 | 0.2124 | 0.2124 |
Mycobacterium ulcerans | beta-lactamase | 0.0149 | 0.1385 | 1 |
Brugia malayi | Ets-domain containing protein | 0.0077 | 0.0617 | 0.2304 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0149 | 0.1385 | 0.5888 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.003 | 0.0106 | 0.0763 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0022 | 0.0021 | 0.0078 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.011 | 0.0409 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0149 | 0.1385 | 0.5069 |
Brugia malayi | Muscleblind-like protein | 0.0145 | 0.1347 | 0.5029 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0218 | 0.2124 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.1385 | 0.5168 |
Leishmania major | hypothetical protein, conserved | 0.0149 | 0.1385 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0086 | 0.0708 | 0.5113 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0149 | 0.1385 | 0.5168 |
Brugia malayi | IPT/TIG domain containing protein | 0.0042 | 0.0234 | 0.0873 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.0234 | 0.6615 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.003 | 0.0106 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.003 | 0.0106 | 0.0763 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0022 | 0.0021 | 0.0078 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0086 | 0.0714 | 0.2663 |
Plasmodium falciparum | thioredoxin reductase | 0.003 | 0.0106 | 0.1492 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.003 | 0.0106 | 0.0763 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0196 | 0.1889 | 0.6825 |
Schistosoma mansoni | hypothetical protein | 0.0133 | 0.121 | 0.4429 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.003 | 0.0106 | 0.0763 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0149 | 0.1385 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.0808 | 0.2958 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.003 | 0.0106 | 0.0763 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0234 | 0.0995 |
Mycobacterium tuberculosis | Conserved protein | 0.0149 | 0.1385 | 0.1385 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0234 | 0.0995 |
Trichomonas vaginalis | Clan MA, family M8, leishmanolysin-like metallopeptidase | 0.0042 | 0.0234 | 0.0995 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.003 | 0.0106 | 0.5 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0149 | 0.1385 | 1 |
Schistosoma mansoni | fibrocystin l | 0.0042 | 0.0234 | 0.0856 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0196 | 0.1889 | 0.1889 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.003 | 0.0106 | 0.0763 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0149 | 0.1385 | 0.1385 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0234 | 0.0995 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.003 | 0.0106 | 0.0394 |
Loa Loa (eye worm) | hypothetical protein | 0.0149 | 0.1385 | 0.5168 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0218 | 0.2124 | 0.2124 |
Brugia malayi | glutathione reductase | 0.0086 | 0.0708 | 0.2643 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0149 | 0.1385 | 0.1385 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0086 | 0.0708 | 0.2643 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.003 | 0.0106 | 1 |
Trichomonas vaginalis | mercuric reductase, putative | 0.003 | 0.0106 | 0.0449 |
Trichomonas vaginalis | set domain proteins, putative | 0.0239 | 0.2352 | 1 |
Brugia malayi | Ets-domain containing protein | 0.0077 | 0.0617 | 0.2304 |
Schistosoma mansoni | plexin | 0.0228 | 0.2232 | 0.817 |
Brugia malayi | beta-lactamase family protein | 0.0149 | 0.1385 | 0.5168 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.0467 | 0.1708 |
Brugia malayi | follicle stimulating hormone receptor | 0.0234 | 0.2295 | 0.8565 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0149 | 0.1385 | 1 |
Schistosoma mansoni | gabp alpha | 0.0077 | 0.0617 | 0.226 |
Brugia malayi | hypothetical protein | 0.0127 | 0.1147 | 0.4279 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.003 | 0.0106 | 0.0763 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.011 | 0.0401 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0808 | 0.3016 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.003 | 0.0106 | 0.0763 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0086 | 0.0708 | 0.0708 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0234 | 0.0995 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0149 | 0.1385 | 0.5069 |
Brugia malayi | Pre-SET motif family protein | 0.021 | 0.2041 | 0.7615 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.003 | 0.0106 | 0.0763 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0149 | 0.1385 | 0.1385 |
Mycobacterium tuberculosis | Conserved protein | 0.0149 | 0.1385 | 0.1385 |
Echinococcus multilocularis | muscleblind protein | 0.0145 | 0.1347 | 0.5029 |
Plasmodium falciparum | thioredoxin reductase | 0.0086 | 0.0708 | 1 |
Trichomonas vaginalis | Clan MA, family M8, leishmanolysin-like metallopeptidase | 0.0042 | 0.0234 | 0.0995 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0086 | 0.0714 | 0.2663 |
Brugia malayi | DNA-binding protein LAG-1 | 0.0042 | 0.0234 | 0.0873 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.