Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | polyprenol reductase, putative | 0.0044 | 0.2692 | 0.5 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.0044 | 0.2692 | 0.2692 |
Entamoeba histolytica | trans-2,3-enoyl-CoA reductase, putative | 0.0044 | 0.2692 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0044 | 0.2692 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0142 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.1223 | 0.1223 |
Schistosoma mansoni | gliotactin | 0.0024 | 0.1223 | 0.1223 |
Plasmodium vivax | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0044 | 0.2692 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.2692 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0024 | 0.1223 | 0.1223 |
Brugia malayi | Carboxylesterase family protein | 0.0024 | 0.1223 | 0.1223 |
Schistosoma mansoni | synaptic glycoprotein sc2 related | 0.0044 | 0.2692 | 0.2692 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0024 | 0.1223 | 0.1223 |
Entamoeba histolytica | 3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein | 0.0044 | 0.2692 | 0.5 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0044 | 0.2692 | 0.5 |
Entamoeba histolytica | steroid 5-alpha reductase, putative | 0.0044 | 0.2692 | 0.5 |
Brugia malayi | hypothetical protein | 0.0024 | 0.1223 | 0.1223 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0142 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.2692 | 0.2692 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0024 | 0.1223 | 0.1223 |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.0044 | 0.2692 | 0.5 |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.0044 | 0.2692 | 0.5 |
Brugia malayi | Synaptic glycoprotein SC2 | 0.0044 | 0.2692 | 0.2692 |
Loa Loa (eye worm) | carboxylesterase | 0.0142 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0024 | 0.1223 | 0.1223 |
Brugia malayi | Carboxylesterase family protein | 0.0142 | 1 | 1 |
Echinococcus multilocularis | synaptic glycoprotein sc2 | 0.0044 | 0.2692 | 0.2692 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.0044 | 0.2692 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0024 | 0.1223 | 0.1223 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0044 | 0.2692 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0024 | 0.1223 | 0.1223 |
Echinococcus multilocularis | neuroligin | 0.0024 | 0.1223 | 0.1223 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0024 | 0.1223 | 0.1223 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0044 | 0.2692 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.1223 | 0.1223 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0024 | 0.1223 | 0.1223 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 1 | 1 |
Onchocerca volvulus | 0.0024 | 0.1223 | 0.4544 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0142 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0024 | 0.1223 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 1 | 1 |
Echinococcus granulosus | 3 oxo 5 alpha steroid 4 dehydrogenase C terminal | 0.0044 | 0.2692 | 0.2692 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0044 | 0.2692 | 1 |
Plasmodium falciparum | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0044 | 0.2692 | 0.5 |
Giardia lamblia | Synaptic glycoprotein SC2 | 0.0044 | 0.2692 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0142 | 1 | 1 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.0044 | 0.2692 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.2692 | 0.2692 |
Trichomonas vaginalis | synaptic glycoprotein sc2, putative | 0.0044 | 0.2692 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0024 | 0.1223 | 0.1223 |
Echinococcus granulosus | neuroligin | 0.0024 | 0.1223 | 0.1223 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0024 | 0.1223 | 0.1223 |
Onchocerca volvulus | 0.0044 | 0.2692 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.1223 | 0.1223 |
Loa Loa (eye worm) | carboxylesterase | 0.0024 | 0.1223 | 0.1223 |
Echinococcus granulosus | carboxylesterase 5A | 0.0142 | 1 | 1 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0044 | 0.2692 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0024 | 0.1223 | 0.1223 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0024 | 0.1223 | 0.1223 |
Onchocerca volvulus | 0.0024 | 0.1223 | 0.4544 | |
Schistosoma mansoni | acetylcholinesterase | 0.0024 | 0.1223 | 0.1223 |
Leishmania major | 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein | 0.0044 | 0.2692 | 0.5 |
Plasmodium vivax | polyprenol reductase, putative | 0.0044 | 0.2692 | 0.5 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0024 | 0.1223 | 0.1223 |
Echinococcus multilocularis | acetylcholinesterase | 0.0142 | 1 | 1 |
Echinococcus multilocularis | 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal | 0.0044 | 0.2692 | 0.2692 |
Trypanosoma cruzi | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0044 | 0.2692 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0044 | 0.2692 | 0.5 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0024 | 0.1223 | 0.5 |
Brugia malayi | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | 0.0044 | 0.2692 | 0.2692 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.1223 | 0.1223 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.1223 | 0.1223 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.1223 | 0.1223 |
Trichomonas vaginalis | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0044 | 0.2692 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.2692 | 0.2692 |
Trypanosoma brucei | 3-oxo-5-alpha-steroid 4-dehydrogenase, putative | 0.0044 | 0.2692 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.2692 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0024 | 0.1223 | 0.1223 |
Onchocerca volvulus | 0.0024 | 0.1223 | 0.4544 | |
Toxoplasma gondii | 3-oxo-5-alpha-steroid 4-dehydrogenase | 0.0044 | 0.2692 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0142 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.1223 | 0.1223 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0142 | 1 | 1 |
Onchocerca volvulus | 0.0024 | 0.1223 | 0.4544 | |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0024 | 0.1223 | 0.1223 |
Onchocerca volvulus | 0.0024 | 0.1223 | 0.4544 | |
Trypanosoma brucei | 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative | 0.0044 | 0.2692 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0024 | 0.1223 | 0.5 |
Echinococcus granulosus | synaptic glycoprotein sc2 | 0.0044 | 0.2692 | 0.2692 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.