Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0116 | 0.1146 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.0201 | 1 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0116 | 0.1146 | 1 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0016 | 0.0064 | 0.0484 |
Echinococcus granulosus | dnaJ subfamily B | 0.0423 | 0.4491 | 0.5288 |
Schistosoma mansoni | zinc finger protein | 0.0024 | 0.0149 | 0.0175 |
Leishmania major | calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative | 0.0116 | 0.1146 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0532 | 0.0983 |
Echinococcus multilocularis | nibrin | 0.0011 | 0.0009 | 0.0009 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.0011 | 0.0009 | 0.000008579 |
Trypanosoma brucei | calpain-like cysteine peptidase, putative | 0.0116 | 0.1146 | 1 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0044 | 0.0363 | 0.0427 |
Trypanosoma cruzi | ISWI complex protein | 0.0018 | 0.0077 | 0.0598 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.0064 | 0.0118 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0029 | 0.0201 | 0.3689 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0076 | 0.071 | 0.1311 |
Trichomonas vaginalis | replication factor C large subunit, putative | 0.0011 | 0.0009 | 0.000008579 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0064 | 0.0075 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0041 | 0.0334 | 0.0394 |
Brugia malayi | Muscleblind-like protein | 0.0325 | 0.3431 | 0.6341 |
Echinococcus granulosus | cpg binding protein | 0.0034 | 0.0252 | 0.0296 |
Loa Loa (eye worm) | hypothetical protein | 0.0325 | 0.3431 | 0.6341 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0394 | 0.0464 |
Mycobacterium ulcerans | NAD-dependent DNA ligase LigA | 0.0011 | 0.0009 | 0.5 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.021 | 0.0387 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0094 | 0.0913 | 0.0913 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0027 | 0.0186 | 0.0219 |
Giardia lamblia | Replication factor C, subunit 1 | 0.0011 | 0.0009 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0094 | 0.0913 | 0.1688 |
Echinococcus multilocularis | protein quaking | 0.0028 | 0.0192 | 0.0192 |
Echinococcus granulosus | nibrin | 0.0011 | 0.0009 | 0.0011 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.024 | 0.0444 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0201 | 1 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0044 | 0.0363 | 0.0363 |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.021 | 0.0387 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0161 | 0.1641 | 0.1641 |
Leishmania major | calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative | 0.0116 | 0.1146 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0252 | 0.0296 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0009 | 0.0017 |
Schistosoma mansoni | chromosome transmission fidelity factor | 0.0011 | 0.0009 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0507 | 0.5411 | 1 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0113 | 0.1114 | 1 |
Mycobacterium leprae | PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) | 0.0011 | 0.0009 | 0.5 |
Onchocerca volvulus | 0.0507 | 0.5411 | 1 | |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.021 | 0.0247 |
Schistosoma mansoni | bromodomain containing protein | 0.0074 | 0.0694 | 0.0817 |
Onchocerca volvulus | 0.003 | 0.021 | 0.0387 | |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.0201 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0064 | 0.0484 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0016 | 0.0064 | 0.2875 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0423 | 0.4491 | 0.4491 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.024 | 0.0283 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.1114 | 0.2059 |
Echinococcus granulosus | microtubule associated protein 2 | 0.079 | 0.8493 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.002 | 0.0106 | 0.0125 |
Toxoplasma gondii | ATPase, AAA family protein | 0.0011 | 0.0009 | 0.0000066768 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0106 | 0.0196 |
Chlamydia trachomatis | DNA ligase | 0.0011 | 0.0009 | 0.5 |
Trypanosoma brucei | calpain-like cysteine peptidase, putative | 0.0116 | 0.1146 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0325 | 0.3431 | 0.3431 |
Brugia malayi | Bromodomain containing protein | 0.0044 | 0.0364 | 0.0673 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0192 | 0.0227 |
Echinococcus multilocularis | protein dispatched 1 | 0.0055 | 0.0488 | 0.0488 |
Brugia malayi | hypothetical protein | 0.0029 | 0.0201 | 0.0371 |
Brugia malayi | ATP dependent DNA ligase C terminal region family protein | 0.0011 | 0.0009 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0009 | 0.0017 |
Trypanosoma brucei | calpain, putative | 0.0116 | 0.1146 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0193 | 0.0356 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0064 | 0.0064 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0076 | 0.071 | 0.6339 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.024 | 0.0283 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0009 | 0.0017 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.0064 | 0.0064 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0027 | 0.0032 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0016 | 0.0064 | 0.2875 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0089 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0651 | 0.1204 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0103 | 0.1005 | 0.1858 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0048 | 0.0413 | 0.0764 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0027 | 0.0186 | 0.0186 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0094 | 0.0913 | 0.1075 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0059 | 0.0528 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0325 | 0.3431 | 0.6341 |
Schistosoma mansoni | hypothetical protein | 0.0423 | 0.4491 | 0.5288 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.0064 | 0.1061 |
Echinococcus multilocularis | protein patched | 0.0048 | 0.0413 | 0.0413 |
Brugia malayi | Pax transcription activation domain interacting protein | 0.0011 | 0.0009 | 0.0017 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0113 | 0.1114 | 0.1312 |
Trypanosoma brucei | calpain-like cysteine peptidase, putative | 0.0116 | 0.1146 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0192 | 0.0227 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0201 | 0.1685 |
Echinococcus granulosus | muscleblind protein | 0.0325 | 0.3431 | 0.404 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0094 | 0.0913 | 0.1075 |
Echinococcus granulosus | hypothetical protein | 0.0028 | 0.0192 | 0.0227 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0077 | 0.0091 |
Treponema pallidum | DNA ligase (lig) | 0.0011 | 0.0009 | 0.5 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.0064 | 0.0075 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0076 | 0.071 | 0.071 |
Brugia malayi | DKFZp564C0469 protein | 0.0011 | 0.0009 | 0.0017 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0027 | 0.0186 | 0.0219 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0048 | 0.0413 | 0.0486 |
Trypanosoma brucei | calpain-like cysteine peptidase, putative | 0.0116 | 0.1146 | 1 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0076 | 0.071 | 0.6161 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0076 | 0.071 | 0.1311 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0076 | 0.071 | 0.0835 |
Trypanosoma cruzi | calpain cysteine peptidase, putative | 0.0116 | 0.1146 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0201 | 0.0371 |
Trypanosoma brucei | variant surface glycoprotein (VSG), putative | 0.0116 | 0.1146 | 1 |
Echinococcus granulosus | zinc finger protein | 0.0024 | 0.0149 | 0.0175 |
Loa Loa (eye worm) | tumor suppressor | 0.0332 | 0.3507 | 0.6481 |
Echinococcus multilocularis | cpg binding protein | 0.0034 | 0.0252 | 0.0252 |
Entamoeba histolytica | Activator 1 140 kDa subunit, putative | 0.0011 | 0.0009 | 0.0000031374 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0016 | 0.0064 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.007 | 0.0651 | 0.1204 |
Trypanosoma brucei | ISWI complex protein | 0.0018 | 0.0077 | 0.0598 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.002 | 0.0099 | 0.0116 |
Trypanosoma cruzi | ISWI complex protein | 0.0018 | 0.0077 | 0.0598 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.007 | 0.0649 | 0.0764 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.002 | 0.0106 | 0.0106 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0094 | 0.0913 | 0.1075 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0011 | 0.0009 | 0.0016 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.002 | 0.0106 | 0.0125 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0365 | 0.0674 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.0064 | 0.1061 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.0201 | 0.1685 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.024 | 0.0283 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.024 | 0.0283 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0394 | 0.0464 |
Brugia malayi | PHD-finger family protein | 0.003 | 0.0215 | 0.0398 |
Brugia malayi | tumor suppressor. | 0.0332 | 0.3507 | 0.6481 |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.0201 | 0.1262 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0113 | 0.1114 | 0.2059 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0394 | 0.0464 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.024 | 0.0444 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0024 | 0.0144 | 0.0265 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0016 | 0.0064 | 0.0484 |
Echinococcus multilocularis | muscleblind protein | 0.0325 | 0.3431 | 0.3431 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.0064 | 0.0064 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0041 | 0.0334 | 0.0334 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0094 | 0.0913 | 0.0913 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0103 | 0.1005 | 0.1858 |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.0064 | 0.0118 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.024 | 0.0283 |
Loa Loa (eye worm) | hypothetical protein | 0.0103 | 0.1005 | 0.1858 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0009 | 0.0017 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0063 | 0.0572 | 0.0674 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0064 | 0.0064 |
Echinococcus granulosus | protein quaking | 0.0028 | 0.0192 | 0.0227 |
Schistosoma mansoni | zinc finger protein | 0.0018 | 0.0077 | 0.0091 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0009 | 0.0017 |
Echinococcus granulosus | geminin | 0.0349 | 0.369 | 0.4345 |
Leishmania major | hypothetical protein, conserved | 0.0018 | 0.0077 | 0.012 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0114 | 0.1133 | 0.1334 |
Echinococcus multilocularis | Protein lozenge | 0.0064 | 0.0579 | 0.0579 |
Loa Loa (eye worm) | runx1 | 0.0064 | 0.0579 | 0.107 |
Brugia malayi | hypothetical protein | 0.0507 | 0.5411 | 1 |
Wolbachia endosymbiont of Brugia malayi | NAD-dependent DNA ligase, Lig | 0.0011 | 0.0009 | 0.5 |
Brugia malayi | CHE-14 protein | 0.0048 | 0.0413 | 0.0764 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.024 | 0.0283 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0013 | 0.0027 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0394 | 0.0729 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0076 | 0.071 | 0.5965 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0076 | 0.071 | 0.6161 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C2, putative | 0.0116 | 0.1146 | 1 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.0064 | 0.0118 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.024 | 0.0444 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0009 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0009 | 0.0017 |
Echinococcus multilocularis | expressed conserved protein | 0.0106 | 0.104 | 0.104 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.024 | 0.0444 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0161 | 0.1641 | 0.1932 |
Schistosoma mansoni | lozenge | 0.0064 | 0.0579 | 0.0682 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.079 | 0.8493 | 0.8493 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.024 | 0.024 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0103 | 0.1005 | 0.1858 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0116 | 0.1146 | 1 |
Echinococcus multilocularis | geminin | 0.0349 | 0.369 | 0.369 |
Schistosoma mansoni | hypothetical protein | 0.007 | 0.0651 | 0.0767 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0076 | 0.071 | 0.0835 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0076 | 0.071 | 0.6161 |
Trypanosoma brucei | calpain-like cysteine peptidase, putative | 0.0116 | 0.1146 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0088 | 0.084 | 0.1553 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.002 | 0.0099 | 0.0116 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.002 | 0.0099 | 0.0116 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.0144 | 0.0169 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.024 | 0.024 |
Echinococcus multilocularis | zinc finger protein | 0.0024 | 0.0149 | 0.0149 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0013 | 0.0027 | 0.0027 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0048 | 0.0413 | 1 |
Schistosoma mansoni | patched 1 | 0.0048 | 0.0413 | 0.0486 |
Schistosoma mansoni | topbp1 | 0.0011 | 0.0009 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0768 | 0.142 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0009 | 0.0017 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0394 | 0.0464 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0094 | 0.0913 | 0.1688 |
Schistosoma mansoni | hypothetical protein | 0.0349 | 0.369 | 0.4345 |
Trypanosoma brucei | calpain-like protein, putative | 0.0116 | 0.1146 | 1 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0113 | 0.1114 | 0.1114 |
Brugia malayi | Temporarily assigned gene name protein 44 | 0.0028 | 0.0193 | 0.0356 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0094 | 0.0913 | 0.1075 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0193 | 0.0356 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0437 | 0.0807 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0413 | 0.0764 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0252 | 0.0296 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.002 | 0.0099 | 0.0099 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.024 | 0.024 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.0011 | 0.0009 | 0.000008579 |
Schistosoma mansoni | microtubule-associated protein tau | 0.079 | 0.8493 | 1 |
Trypanosoma brucei | hypothetical protein | 0.0116 | 0.1146 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.0201 | 0.1685 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0094 | 0.0913 | 0.1075 |
Schistosoma mansoni | hypothetical protein | 0.0349 | 0.369 | 0.4345 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0116 | 0.1146 | 1 |
Echinococcus granulosus | expressed conserved protein | 0.0106 | 0.104 | 0.1224 |
Schistosoma mansoni | topbp1 | 0.0011 | 0.0009 | 0.0011 |
Brugia malayi | topoisomerase | 0.0011 | 0.0009 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0507 | 0.5411 | 1 |
Schistosoma mansoni | DNA ligase IV | 0.0011 | 0.0009 | 0.0011 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.007 | 0.0649 | 0.0649 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0064 | 0.0064 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.024 | 0.0283 |
Onchocerca volvulus | 0.0011 | 0.0009 | 0.0017 | |
Echinococcus multilocularis | replication factor c subunit 1 | 0.0011 | 0.0009 | 0.0009 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0064 | 0.0484 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0048 | 0.0413 | 0.0486 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0048 | 0.0413 | 0.0413 |
Echinococcus granulosus | replication factor c subunit 1 | 0.0011 | 0.0009 | 0.0011 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.002 | 0.0106 | 0.0125 |
Loa Loa (eye worm) | bromodomain containing protein | 0.002 | 0.0107 | 0.0197 |
Leishmania major | calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative | 0.0116 | 0.1146 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 29.9349 uM | PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 89.1251 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] | ChEMBL. | No reference |
Potency (functional) | 100 uM | PubChem BioAssay. qHTS for Antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1): primary screen. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.