Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | cruzipain precursor, putative | 0.0164 | 0.2283 | 0.2283 |
Echinococcus granulosus | flap endonuclease 1 | 0.003 | 0.0007 | 0.0007 |
Brugia malayi | Flap endonuclease-1 | 0.003 | 0.0007 | 0.0007 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0032 | 0.0041 | 0.0041 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0032 | 0.0041 | 0.0058 |
Loa Loa (eye worm) | hypothetical protein | 0.0335 | 0.5186 | 0.5186 |
Brugia malayi | AMP-binding enzyme family protein | 0.01 | 0.1205 | 0.1205 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.01 | 0.1205 | 0.369 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0041 | 0.0058 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Leishmania major | malate dehydrogenase, putative | 0.0448 | 0.7102 | 0.7102 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.01 | 0.1205 | 0.369 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0041 | 0.0058 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0032 | 0.0041 | 0.0058 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0032 | 0.0041 | 0.0041 |
Brugia malayi | cathepsin L-like precursor | 0.0041 | 0.0203 | 0.0203 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0041 | 0.0058 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0164 | 0.2283 | 0.2283 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.01 | 0.1205 | 0.1696 |
Leishmania major | glycosomal malate dehydrogenase | 0.0215 | 0.3147 | 0.3147 |
Trichomonas vaginalis | malate and lactate dehydrogenase, putative | 0.0222 | 0.3264 | 1 |
Entamoeba histolytica | malate dehydrogenase,cytoplasmic, putative | 0.0222 | 0.3264 | 0.4596 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0041 | 0.0203 | 0.0623 |
Loa Loa (eye worm) | flap endonuclease-1 | 0.003 | 0.0007 | 0.0007 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0619 | 1 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0071 | 0.0704 | 0.2156 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0164 | 0.2283 | 0.2283 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0335 | 0.5186 | 0.5186 |
Echinococcus multilocularis | cysteine protease | 0.0062 | 0.0551 | 0.0551 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0041 | 0.0058 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0088 | 0.0992 | 0.3037 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0774 | 0.0774 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0222 | 0.3264 | 1 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0039 | 0.0162 | 0.0162 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0774 | 0.0774 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0032 | 0.0041 | 0.0058 |
Trichomonas vaginalis | malate and lactate dehydrogenase, putative | 0.0222 | 0.3264 | 1 |
Echinococcus multilocularis | flap endonuclease 1 | 0.003 | 0.0007 | 0.0007 |
Schistosoma mansoni | hypothetical protein | 0.0335 | 0.5186 | 0.5186 |
Echinococcus multilocularis | lamin | 0.0059 | 0.0503 | 0.0503 |
Trypanosoma cruzi | mitochondrial malate dehydrogenase, putative | 0.0215 | 0.3147 | 0.3147 |
Echinococcus granulosus | lamin dm0 | 0.0059 | 0.0503 | 0.0503 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0098 | 0.1158 | 0.3547 |
Wolbachia endosymbiont of Brugia malayi | malate dehydrogenase | 0.0448 | 0.7102 | 0.5 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0062 | 0.0551 | 0.0551 |
Brugia malayi | intermediate filament protein | 0.0059 | 0.0503 | 0.0503 |
Plasmodium vivax | lactate dehydrogenase | 0.0448 | 0.7102 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0032 | 0.0041 | 0.0041 |
Entamoeba histolytica | Flap nuclease, putative | 0.003 | 0.0007 | 0.001 |
Echinococcus multilocularis | musashi | 0.0059 | 0.0503 | 0.0503 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0222 | 0.3264 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.01 | 0.1205 | 0.1205 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0041 | 0.0203 | 0.0203 |
Trypanosoma cruzi | malate dehydrogenase, putative | 0.0197 | 0.2835 | 0.2835 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0222 | 0.3264 | 1 |
Echinococcus multilocularis | malate dehydrogenase | 0.0215 | 0.3147 | 0.3147 |
Schistosoma mansoni | intermediate filament proteins | 0.0059 | 0.0503 | 0.0503 |
Echinococcus granulosus | malate dehydrogenase | 0.0215 | 0.3147 | 0.3147 |
Plasmodium falciparum | thioredoxin reductase | 0.0039 | 0.0153 | 0.0216 |
Trypanosoma brucei | glycosomal malate dehydrogenase | 0.0215 | 0.3147 | 0.3147 |
Echinococcus granulosus | carbonic anhydrase | 0.0335 | 0.5186 | 0.5186 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Brugia malayi | AMP-binding enzyme family protein | 0.01 | 0.1205 | 0.1205 |
Trypanosoma brucei | trypanothione reductase | 0.0039 | 0.0153 | 0.0153 |
Loa Loa (eye worm) | cysteine protease | 0.0062 | 0.0551 | 0.0551 |
Brugia malayi | Cathepsin L-like precursor | 0.0041 | 0.0203 | 0.0203 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0484 | 0.0484 |
Mycobacterium tuberculosis | Probable reductase | 0.0088 | 0.0992 | 0.3037 |
Echinococcus granulosus | intermediate filament protein | 0.0059 | 0.0503 | 0.0503 |
Loa Loa (eye worm) | hypothetical protein | 0.0335 | 0.5186 | 0.5186 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0619 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0164 | 0.2283 | 0.2283 |
Plasmodium vivax | vivapain-2 | 0.0062 | 0.0551 | 0.0776 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0032 | 0.0041 | 0.0058 |
Trypanosoma brucei | mitochondrial malate dehydrogenase | 0.0215 | 0.3147 | 0.3147 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0088 | 0.0992 | 0.3037 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.01 | 0.1205 | 0.369 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0203 | 0.0203 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0041 | 0.0058 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.01 | 0.1205 | 0.369 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0335 | 0.5186 | 0.5186 |
Echinococcus granulosus | cathepsin l1 | 0.0041 | 0.0203 | 0.0203 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.01 | 0.1205 | 0.369 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0551 | 0.0551 |
Trypanosoma brucei | cytosolic malate dehydrogenase | 0.0222 | 0.3264 | 0.3264 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0335 | 0.5186 | 0.5186 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0551 | 0.0551 |
Brugia malayi | Malate dehydrogenase, cytoplasmic | 0.0222 | 0.3264 | 0.3264 |
Trypanosoma cruzi | cytosolic malate dehydrogenase, putative | 0.0222 | 0.3264 | 0.3264 |
Entamoeba histolytica | malate dehydrogenase, putative | 0.0448 | 0.7102 | 1 |
Leishmania major | malate dehydrogenase, putative | 0.0197 | 0.2835 | 0.2835 |
Brugia malayi | Cathepsin L-like precursor | 0.0062 | 0.0551 | 0.0551 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0032 | 0.0037 | 0.0037 |
Toxoplasma gondii | hypothetical protein | 0.0335 | 0.5186 | 0.7302 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0041 | 0.0058 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0203 | 0.0203 |
Schistosoma mansoni | malate dehydrogenase | 0.0222 | 0.3264 | 0.3264 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0039 | 0.0153 | 0.0216 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0062 | 0.0551 | 0.0776 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0551 | 0.0551 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0062 | 0.0551 | 0.0551 |
Schistosoma mansoni | malate dehydrogenase | 0.0448 | 0.7102 | 0.7102 |
Trichomonas vaginalis | malate and lactate dehydrogenase, putative | 0.0222 | 0.3264 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0098 | 0.1158 | 0.3547 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.01 | 0.1205 | 0.1696 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0335 | 0.5186 | 0.5186 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0041 | 0.0203 | 0.0623 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0032 | 0.0041 | 0.0041 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0062 | 0.0551 | 0.0776 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0041 | 0.0058 |
Echinococcus multilocularis | cathepsin L | 0.0032 | 0.0041 | 0.0041 |
Trypanosoma cruzi | cysteine protease, putative | 0.0032 | 0.0041 | 0.0041 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0335 | 0.5186 | 0.5186 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0164 | 0.2283 | 0.2283 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0335 | 0.5186 | 0.5186 |
Plasmodium vivax | vivapain-3 | 0.0032 | 0.0041 | 0.0058 |
Echinococcus granulosus | carbonic anhydrase II | 0.0619 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0041 | 0.0058 |
Onchocerca volvulus | 0.0062 | 0.0551 | 0.4576 | |
Loa Loa (eye worm) | hypothetical protein | 0.0448 | 0.7102 | 0.7102 |
Leishmania major | trypanothione reductase | 0.0039 | 0.0153 | 0.0153 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0041 | 0.0203 | 0.0286 |
Echinococcus granulosus | L lactate dehydrogenase B chain | 0.0448 | 0.7102 | 0.7102 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0164 | 0.2283 | 0.2283 |
Echinococcus multilocularis | cytosolic malate dehydrogenase | 0.0222 | 0.3264 | 0.3264 |
Echinococcus granulosus | lactate dehydrogenase protein | 0.0448 | 0.7102 | 0.7102 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0222 | 0.3264 | 1 |
Leishmania major | carbonic anhydrase-like protein | 0.0619 | 1 | 1 |
Echinococcus granulosus | lactate dehydrogenase a | 0.0448 | 0.7102 | 0.7102 |
Echinococcus granulosus | cytosolic malate dehydrogenase | 0.0222 | 0.3264 | 0.3264 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0619 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0551 | 0.0776 |
Plasmodium falciparum | flap endonuclease 1 | 0.003 | 0.0007 | 0.001 |
Trichomonas vaginalis | flap endonuclease-1, putative | 0.003 | 0.0007 | 0.0023 |
Brugia malayi | lactate dehydrogenase. | 0.0448 | 0.7102 | 0.7102 |
Schistosoma mansoni | carbonic anhydrase | 0.0335 | 0.5186 | 0.5186 |
Schistosoma mansoni | lamin | 0.0059 | 0.0503 | 0.0503 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0032 | 0.0041 | 0.0041 |
Echinococcus granulosus | cathepsin L | 0.0032 | 0.0041 | 0.0041 |
Onchocerca volvulus | 0.0062 | 0.0551 | 0.4576 | |
Echinococcus granulosus | lactate dehydrogenase a | 0.0448 | 0.7102 | 0.7102 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0098 | 0.1158 | 0.3547 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0113 | 0.1425 | 0.1425 |
Schistosoma mansoni | L-lactate dehydrogenase | 0.0448 | 0.7102 | 0.7102 |
Onchocerca volvulus | Cathepsin L homolog | 0.0062 | 0.0551 | 0.4576 |
Echinococcus multilocularis | cytosolic malate dehydrogenase | 0.0222 | 0.3264 | 0.3264 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Trypanosoma cruzi | malate dehydrogenase, putative | 0.0215 | 0.3147 | 0.3147 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.01 | 0.1205 | 0.1696 |
Leishmania major | cytosolic malate dehydrogenase | 0.0222 | 0.3264 | 0.3264 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Echinococcus multilocularis | lactate dehydrogenase a | 0.0448 | 0.7102 | 0.7102 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0032 | 0.0041 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0774 | 0.0774 |
Leishmania major | cathepsin L-like protease | 0.0164 | 0.2283 | 0.2283 |
Toxoplasma gondii | cathepsin CPL | 0.0062 | 0.0551 | 0.0776 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0222 | 0.3264 | 1 |
Plasmodium falciparum | lactate dehydrogenase, putative | 0.0197 | 0.2835 | 0.3992 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0032 | 0.0041 | 0.0041 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0619 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0062 | 0.0551 | 0.0551 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0032 | 0.0041 | 0.0041 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0619 | 1 | 1 |
Entamoeba histolytica | malate dehydrogenase, putative | 0.0222 | 0.3264 | 0.4596 |
Echinococcus granulosus | cytosolic malate dehydrogenase | 0.0222 | 0.3264 | 0.3264 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0619 | 1 | 1 |
Brugia malayi | glutathione reductase | 0.0039 | 0.0153 | 0.0153 |
Onchocerca volvulus | 0.01 | 0.1205 | 1 | |
Brugia malayi | Papain family cysteine protease containing protein | 0.0062 | 0.0551 | 0.0551 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0071 | 0.0704 | 0.2156 |
Leishmania major | mitochondrial malate dehydrogenase | 0.0215 | 0.3147 | 0.3147 |
Leishmania major | cysteine peptidase A (CPA) | 0.0062 | 0.0551 | 0.0551 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0222 | 0.3264 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0062 | 0.0551 | 0.0551 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0062 | 0.0551 | 0.0551 |
Toxoplasma gondii | malate dehydrogenase MDH | 0.0448 | 0.7102 | 1 |
Echinococcus multilocularis | malate dehydrogenase | 0.0215 | 0.3147 | 0.3147 |
Echinococcus granulosus | L lactate dehydrogenase | 0.0251 | 0.3766 | 0.3766 |
Echinococcus multilocularis | carbonic anhydrase | 0.0335 | 0.5186 | 0.5186 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0032 | 0.0041 | 0.0041 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0164 | 0.2283 | 0.2283 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0222 | 0.3264 | 1 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0121 | 0.1554 | 0.4759 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0164 | 0.2283 | 0.2283 |
Chlamydia trachomatis | malate dehydrogenase | 0.0222 | 0.3264 | 1 |
Echinococcus multilocularis | lactate dehydrogenase protein | 0.0448 | 0.7102 | 0.7102 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Trypanosoma brucei | flap endonuclease-1 (FEN-1), putative | 0.003 | 0.0007 | 0.0007 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0062 | 0.0551 | 0.0776 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Brugia malayi | Cathepsin L-like precursor | 0.0041 | 0.0203 | 0.0203 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1205 | 0.1205 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0551 | 0.0551 |
Toxoplasma gondii | lactate dehydrogenase LDH2 | 0.0448 | 0.7102 | 1 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0088 | 0.0992 | 0.3037 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0551 | 0.0551 |
Echinococcus multilocularis | carbonic anhydrase | 0.0335 | 0.5186 | 0.5186 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0039 | 0.0153 | 0.0153 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.01 | 0.1205 | 0.369 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0039 | 0.0153 | 0.0153 |
Toxoplasma gondii | lactate dehydrogenase LDH1 | 0.0448 | 0.7102 | 1 |
Onchocerca volvulus | 0.0062 | 0.0551 | 0.4576 | |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0032 | 0.0041 | 0.0041 |
Schistosoma mansoni | lamin | 0.0059 | 0.0503 | 0.0503 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Leishmania major | flap endonuclease-1 (FEN-1), putative | 0.003 | 0.0007 | 0.0007 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0071 | 0.0704 | 0.2156 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0032 | 0.0041 | 0.0058 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0041 | 0.0058 |
Echinococcus granulosus | malate dehydrogenase | 0.0215 | 0.3147 | 0.3147 |
Trypanosoma cruzi | glycosomal malate dehydrogenase, putative | 0.0215 | 0.3147 | 0.3147 |
Schistosoma mansoni | malate dehydrogenase | 0.0222 | 0.3264 | 0.3264 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0075 | 0.0774 | 0.237 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0041 | 0.0203 | 0.0203 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0062 | 0.0551 | 0.0776 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0032 | 0.0041 | 0.0126 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0144 | 0.1935 | 0.1935 |
Plasmodium falciparum | malate dehydrogenase | 0.0448 | 0.7102 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0062 | 0.0551 | 0.0776 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0032 | 0.0037 | 0.0037 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0039 | 0.0162 | 0.0162 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0335 | 0.5186 | 0.5186 |
Leishmania major | malate dehydrogenase | 0.0215 | 0.3147 | 0.3147 |
Mycobacterium leprae | PROBABLE MALATE DEHYDROGENASE MDH | 0.0222 | 0.3264 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0774 | 0.0774 |
Mycobacterium ulcerans | malate dehydrogenase | 0.0222 | 0.3264 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0062 | 0.0551 | 0.0551 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0335 | 0.5186 | 0.5186 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0164 | 0.2283 | 0.2283 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1205 | 0.1205 |
Echinococcus granulosus | carbonic anhydrase | 0.0335 | 0.5186 | 0.5186 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0164 | 0.2283 | 0.2283 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0222 | 0.3264 | 1 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0619 | 1 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.01 | 0.1205 | 0.369 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0062 | 0.0551 | 0.0551 |
Trypanosoma cruzi | glycosomal malate dehydrogenase, putative | 0.0215 | 0.3147 | 0.3147 |
Trypanosoma brucei | malate dehydrogenase-related | 0.0197 | 0.2835 | 0.2835 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0062 | 0.0551 | 0.0551 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0041 | 0.0058 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Brugia malayi | Probable malate dehydrogenase, mitochondrial precursor | 0.0215 | 0.3147 | 0.3147 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0075 | 0.0774 | 0.1089 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Onchocerca volvulus | Cathepsin L homolog | 0.0062 | 0.0551 | 0.4576 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0088 | 0.0992 | 0.3037 |
Onchocerca volvulus | 0.0041 | 0.0203 | 0.1689 | |
Onchocerca volvulus | Cathepsin F homolog | 0.0062 | 0.0551 | 0.4576 |
Echinococcus granulosus | cysteine protease | 0.0032 | 0.0041 | 0.0041 |
Leishmania major | cathepsin L-like protease | 0.0164 | 0.2283 | 0.2283 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0098 | 0.1158 | 0.3547 |
Onchocerca volvulus | 0.0062 | 0.0551 | 0.4576 | |
Plasmodium falciparum | glutathione reductase | 0.0039 | 0.0153 | 0.0216 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0032 | 0.0041 | 0.0058 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0062 | 0.0551 | 0.0551 |
Plasmodium vivax | lactate/malate dehydrogenase, putative | 0.0197 | 0.2835 | 0.3992 |
Trichomonas vaginalis | malate and lactate dehydrogenase, putative | 0.0222 | 0.3264 | 1 |
Plasmodium vivax | glutathione reductase, putative | 0.0039 | 0.0153 | 0.0216 |
Echinococcus multilocularis | lactate dehydrogenase a | 0.0448 | 0.7102 | 0.7102 |
Brugia malayi | Thioredoxin reductase | 0.0039 | 0.0153 | 0.0153 |
Loa Loa (eye worm) | hypothetical protein | 0.0335 | 0.5186 | 0.5186 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0551 | 0.0551 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Loa Loa (eye worm) | glutathione reductase | 0.0039 | 0.0153 | 0.0153 |
Loa Loa (eye worm) | malate dehydrogenase | 0.0215 | 0.3147 | 0.3147 |
Mycobacterium tuberculosis | Probable malate dehydrogenase Mdh | 0.0222 | 0.3264 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0774 | 0.0774 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0075 | 0.0774 | 0.1089 |
Echinococcus multilocularis | L lactate dehydrogenase | 0.0251 | 0.3766 | 0.3766 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0222 | 0.3264 | 1 |
Plasmodium vivax | malate dehydrogenase, putative | 0.0448 | 0.7102 | 1 |
Echinococcus multilocularis | lactate dehydrogenase a | 0.0448 | 0.7102 | 0.7102 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.01 | 0.1205 | 0.1205 |
Plasmodium vivax | vivapain-2 | 0.0062 | 0.0551 | 0.0776 |
Plasmodium vivax | unspecified product | 0.0032 | 0.0041 | 0.0058 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0088 | 0.0992 | 0.3037 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.01 | 0.1205 | 0.369 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0164 | 0.2283 | 0.2283 |
Giardia lamblia | Malate dehydrogenase | 0.0222 | 0.3264 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.01 | 0.1205 | 0.369 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0088 | 0.0992 | 0.3037 |
Onchocerca volvulus | 0.0062 | 0.0551 | 0.4576 | |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0335 | 0.5186 | 0.5186 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Loa Loa (eye worm) | fibroinase | 0.0062 | 0.0551 | 0.0551 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0059 | 0.0503 | 0.0503 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0041 | 0.0058 |
Echinococcus multilocularis | carbonic anhydrase | 0.0335 | 0.5186 | 0.5186 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.01 | 0.1205 | 0.369 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0203 | 0.0203 |
Echinococcus granulosus | lamin | 0.0059 | 0.0503 | 0.0503 |
Echinococcus granulosus | carbonic anhydrase | 0.0335 | 0.5186 | 0.5186 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Plasmodium falciparum | carbonic anhydrase | 0.0335 | 0.5186 | 0.7302 |
Leishmania major | cathepsin L-like protease | 0.0164 | 0.2283 | 0.2283 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0164 | 0.2283 | 0.2283 |
Echinococcus multilocularis | cysteine protease | 0.0062 | 0.0551 | 0.0551 |
Echinococcus granulosus | cathepsin l1 | 0.0062 | 0.0551 | 0.0551 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1205 | 0.1205 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0222 | 0.3264 | 1 |
Echinococcus multilocularis | L lactate dehydrogenase B chain | 0.0448 | 0.7102 | 0.7102 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.01 | 0.1205 | 0.369 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.01 | 0.1205 | 0.1205 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0059 | 0.0503 | 0.0503 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.01 | 0.1205 | 0.1205 |
Schistosoma mansoni | L-lactate dehydrogenase | 0.0197 | 0.2835 | 0.2835 |
Loa Loa (eye worm) | malate dehydrogenase | 0.0222 | 0.3264 | 0.3264 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0032 | 0.0041 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0503 | 0.0503 |
Plasmodium falciparum | L-lactate dehydrogenase | 0.0448 | 0.7102 | 1 |
Onchocerca volvulus | 0.0059 | 0.0503 | 0.4172 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0164 | 0.2283 | 0.2283 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0164 | 0.2283 | 0.2283 |
Toxoplasma gondii | flap structure-specific endonuclease 1, putative | 0.003 | 0.0007 | 0.001 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0551 | 0.1689 |
Brugia malayi | Cathepsin L-like precursor | 0.0062 | 0.0551 | 0.0551 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0039 | 0.0153 | 0.047 |
Loa Loa (eye worm) | ctsf protein | 0.0062 | 0.0551 | 0.0551 |
Onchocerca volvulus | 0.0062 | 0.0551 | 0.4576 | |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0096 | 0.1125 | 0.3445 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0041 | 0.0058 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0032 | 0.0041 | 0.0058 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0062 | 0.0551 | 0.0551 |
Plasmodium vivax | flap endonuclease 1, putative | 0.003 | 0.0007 | 0.001 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0062 | 0.0551 | 0.0551 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0071 | 0.0704 | 0.2156 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0197 | 0.2835 | 0.8686 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0164 | 0.2283 | 0.2283 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.0551 | 0.0551 |
Echinococcus multilocularis | lamin dm0 | 0.0059 | 0.0503 | 0.0503 |
Schistosoma mansoni | malate dehydrogenase | 0.0215 | 0.3147 | 0.3147 |
Plasmodium vivax | vivapain-1 | 0.0032 | 0.0041 | 0.0058 |
Onchocerca volvulus | 0.0059 | 0.0503 | 0.4172 | |
Onchocerca volvulus | 0.0062 | 0.0551 | 0.4576 | |
Trypanosoma cruzi | flap endonuclease-1 (FEN-1), putative | 0.003 | 0.0007 | 0.0007 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0619 | 1 | 1 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0619 | 1 | 1 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0075 | 0.0774 | 0.237 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.01 | 0.1205 | 0.369 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0032 | 0.0041 | 0.0041 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0041 | 0.0058 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0062 | 0.0551 | 0.0551 |
Brugia malayi | Cathepsin L-like precursor | 0.0062 | 0.0551 | 0.0551 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0032 | 0.0041 | 0.0126 |
Trypanosoma cruzi | cytosolic malate dehydrogenase, putative | 0.0222 | 0.3264 | 0.3264 |
Brugia malayi | Cathepsin L-like precursor | 0.0062 | 0.0551 | 0.0551 |
Trichomonas vaginalis | malate dehydrogenase, putative | 0.0222 | 0.3264 | 1 |
Toxoplasma gondii | thioredoxin reductase | 0.0039 | 0.0153 | 0.0216 |
Loa Loa (eye worm) | intermediate filament protein | 0.0059 | 0.0503 | 0.0503 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.