Detailed information for compound 1479659

Basic information

Technical information
  • TDR Targets ID: 1479659
  • Name: (2S)-2-amino-5-(1-aminoethylideneamino)pentan oic acid hydrochloride
  • MW: 209.674 | Formula: C7H16ClN3O2
  • H donors: 3 H acceptors: 2 LogP: -2.45 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=N)NCCC[C@@H](C(=O)O)N.Cl
  • InChi: 1S/C7H15N3O2.ClH/c1-5(8)10-4-2-3-6(9)7(11)12;/h6H,2-4,9H2,1H3,(H2,8,10)(H,11,12);1H/t6-;/m0./s1
  • InChiKey: JIBZSGQTCBWUKL-RGMNGODLSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-2-amino-5-(1-aminoethylideneamino)valeric acid hydrochloride
  • 150403-88-6
  • EU-0100683

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0712 0.5
Schistosoma mansoni nAChR subunit 0.0019 0.0236 0.0236
Onchocerca volvulus 0.003 0.0878 0.0748
Loa Loa (eye worm) hypothetical protein 0.0016 0.0034 0.0038
Brugia malayi Nuclear hormone receptor family member nhr-1 0.003 0.0878 0.0996
Loa Loa (eye worm) hypothetical protein 0.003 0.0878 0.0996
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0104 0.0118
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0015 0 0.5
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0236 0.0268
Brugia malayi Cation transporter family protein 0.0019 0.0236 0.0268
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0019 0.0236 0.0268
Loa Loa (eye worm) hypothetical protein 0.003 0.0878 0.0996
Onchocerca volvulus 0.0029 0.0825 0.0686
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0712 0.5
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0019 0.0236 0.0268
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0878 0.0878
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.003 0.0878 0.0878
Brugia malayi Cytochrome P450 family protein 0.0036 0.1229 0.1393
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.003 0.0878 0.0878
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0019 0.0236 0.0268
Loa Loa (eye worm) hypothetical protein 0.0019 0.0236 0.0268
Echinococcus multilocularis thyroid hormone receptor alpha 0.003 0.0878 0.0878
Brugia malayi nuclear receptor NHR-88 0.003 0.0878 0.0996
Loa Loa (eye worm) hypothetical protein 0.0017 0.0104 0.0118
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0104 0.0104
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0236 0.0268
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0878 0.0878
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0019 0.0236 0.0236
Schistosoma mansoni jun-related protein 0.0074 0.3483 0.3483
Schistosoma mansoni nAChR subunit 0.0019 0.0236 0.0236
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0236 0.0236
Loa Loa (eye worm) MH2 domain-containing protein 0.013 0.6776 0.7684
Echinococcus multilocularis ecdysone induced protein 78C 0.003 0.0878 0.0878
Schistosoma mansoni thyroid hormone receptor 0.003 0.0878 0.0878
Echinococcus granulosus GPCR family 2 0.0017 0.0104 0.0104
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0034 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-40 0.003 0.0878 0.0996
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0019 0.0236 0.0268
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0015 0 0.5
Echinococcus multilocularis musashi 0.0029 0.0825 0.0825
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0015 0 0.5
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.003 0.0878 0.0996
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.003 0.0878 0.0748
Echinococcus granulosus lamin 0.0029 0.0825 0.0825
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0878 0.0996
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0019 0.0236 0.0268
Loa Loa (eye worm) steroid hormone receptor 0.003 0.0878 0.0996
Brugia malayi Nuclear hormone receptor family member nhr-14 0.003 0.0878 0.0996
Brugia malayi hypothetical protein 0.0016 0.0034 0.0038
Brugia malayi Cation transporter family protein 0.0019 0.0236 0.0268
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0019 0.0236 0.0236
Brugia malayi Nuclear hormone receptor family member nhr-41 0.003 0.0878 0.0996
Loa Loa (eye worm) CYP4Cod1 0.0025 0.0564 0.064
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0019 0.0236 0.0268
Echinococcus granulosus nAChR subunit 0.0019 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0089 0.4348 0.493
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0564 0.7928
Loa Loa (eye worm) hypothetical protein 0.0016 0.0034 0.0038
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0019 0.0236 0.0268
Brugia malayi Nuclear hormone receptor family member nhr-31 0.003 0.0878 0.0996
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0015 0 0.5
Brugia malayi intermediate filament protein 0.0029 0.0825 0.0936
Brugia malayi Nuclear hormone receptor family member nhr-19 0.003 0.0878 0.0996
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0236 0.0268
Brugia malayi hypothetical protein 0.0018 0.0136 0.0155
Onchocerca volvulus Bile acid receptor homolog 0.003 0.0878 0.0748
Echinococcus multilocularis glycine receptor subunit beta 0.0019 0.0236 0.0236
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0015 0 0.5
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.003 0.0878 0.0878
Echinococcus multilocularis glycine receptor subunit beta 0.0019 0.0236 0.0236
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0236 0.0268
Brugia malayi hypothetical protein 0.0072 0.3335 0.3781
Loa Loa (eye worm) hypothetical protein 0.0019 0.0236 0.0268
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.003 0.0878 0.0878
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.003 0.0878 0.0996
Schistosoma mansoni coup transcription factor 0.003 0.0878 0.0878
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.2299 0.2606
Loa Loa (eye worm) hypothetical protein 0.003 0.0878 0.0996
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0019 0.0236 0.0236
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0236 0.0268
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0015 0 0.5
Schistosoma mansoni nuclear hormone receptor 0.003 0.0878 0.0878
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0034 0.0038
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0019 0.0236 0.0268
Schistosoma mansoni hypothetical protein 0.0017 0.0104 0.0104
Onchocerca volvulus 0.0165 0.8819 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.003 0.0878 0.0878
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.003 0.0878 0.0996
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.003 0.0878 0.0996
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0712 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0034 0.0038
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0236 0.0236
Echinococcus granulosus glycine receptor subunit beta 0.0019 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0016 0.0034 0.0038
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0104 0.0118
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0712 0.5
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0019 0.0236 0.0268
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0712 1
Schistosoma mansoni nAChR subunit 0.0019 0.0236 0.0236
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0015 0 0.5
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0015 0 0.5
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0015 0 0.5
Onchocerca volvulus Protein ultraspiracle homolog 0.003 0.0878 0.0748
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0019 0.0236 0.0268
Brugia malayi nuclear hormone receptor 0.003 0.0878 0.0996
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0019 0.0021
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0236 0.0236
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0015 0 0.5
Loa Loa (eye worm) cytochrome P450 family protein 0.0036 0.1229 0.1393
Schistosoma mansoni hypothetical protein 0.0017 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0165 0.8819 1
Brugia malayi steroid hormone receptor 0.003 0.0878 0.0996
Echinococcus granulosus ecdysone induced protein 78C 0.003 0.0878 0.0878
Brugia malayi Nuclear hormone receptor family member nhr-3 0.003 0.0878 0.0996
Echinococcus multilocularis geminin 0.0185 1 1
Schistosoma mansoni hypothetical protein 0.0037 0.1283 0.1283
Loa Loa (eye worm) hypothetical protein 0.003 0.0878 0.0996
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.003 0.0878 0.0878
Loa Loa (eye worm) hypothetical protein 0.0019 0.0236 0.0268
Brugia malayi Steroid receptor seven-up type 2 0.003 0.0878 0.0996
Loa Loa (eye worm) hypothetical protein 0.0019 0.0236 0.0268
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0015 0 0.5
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0034 0.0034
Loa Loa (eye worm) transcription factor SMAD2 0.013 0.6776 0.7684
Schistosoma mansoni hypothetical protein 0.0185 1 1
Schistosoma mansoni RAR-like nuclear receptor 0.003 0.0878 0.0878
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0015 0 0.5
Brugia malayi hypothetical protein 0.0165 0.8819 1
Loa Loa (eye worm) ACC-1 protein 0.0019 0.0236 0.0268
Schistosoma mansoni hypothetical protein 0.0074 0.3483 0.3483
Brugia malayi Cytochrome P450 family protein 0.0025 0.0564 0.064
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0019 0.0021
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0034 0.0034
Brugia malayi MH2 domain containing protein 0.013 0.6776 0.7684
Onchocerca volvulus 0.0029 0.0825 0.0686
Echinococcus granulosus jun protein 0.0092 0.4496 0.4496
Loa Loa (eye worm) hypothetical protein 0.003 0.0878 0.0996
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.1283 0.1455
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.003 0.0878 0.0996
Brugia malayi Nuclear hormone receptor-like 1 0.003 0.0878 0.0996
Echinococcus granulosus lamin dm0 0.0029 0.0825 0.0825
Schistosoma mansoni steroid hormone receptor ad4bp 0.003 0.0878 0.0878
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0015 0 0.5
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0019 0.0236 0.0268
Schistosoma mansoni nAChR subunit 0.0019 0.0236 0.0236
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0092 0.4496 0.4496
Schistosoma mansoni lamin 0.0029 0.0825 0.0825
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0019 0.0236 0.0236
Schistosoma mansoni nAChR subunit 0.0019 0.0236 0.0236
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0019 0.0236 0.0268
Echinococcus granulosus retinoic acid receptor rxr beta a 0.003 0.0878 0.0878
Brugia malayi nuclear receptor RXR 0.0016 0.0034 0.0038
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0092 0.4496 0.4496
Brugia malayi Cytochrome P450 family protein 0.0025 0.0564 0.064
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0015 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0016 0.0034 0.0038
Loa Loa (eye worm) hypothetical protein 0.0019 0.0236 0.0268
Schistosoma mansoni lamin 0.0029 0.0825 0.0825
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0019 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0019 0.0236 0.0268
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0019 0.0236 0.0236
Brugia malayi hypothetical protein 0.0027 0.0712 0.0807
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.003 0.0878 0.0996
Loa Loa (eye worm) hypothetical protein 0.0029 0.0825 0.0936
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0825 0.0936
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0015 0 0.5
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0019 0.0236 0.0236
Brugia malayi Nuclear hormone receptor family member nhr-49 0.003 0.0878 0.0996
Loa Loa (eye worm) LGC-31 protein 0.0019 0.0236 0.0268
Brugia malayi bZIP transcription factor family protein 0.0092 0.4496 0.5098
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0564 0.064
Loa Loa (eye worm) hypothetical protein 0.0019 0.0236 0.0268
Loa Loa (eye worm) hypothetical protein 0.0019 0.0236 0.0268
Brugia malayi photoreceptor-specific nuclear receptor 0.003 0.0878 0.0996
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0104 0.0104
Echinococcus multilocularis lamin dm0 0.0029 0.0825 0.0825
Mycobacterium leprae Conserved hypothetical protein 0.0015 0 0.5
Schistosoma mansoni retinoic acid receptor RXR 0.003 0.0878 0.0878
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0019 0.0236 0.0236
Echinococcus granulosus glycine receptor subunit alpha 1 0.0019 0.0236 0.0236
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0019 0.0236 0.0268
Loa Loa (eye worm) hypothetical protein 0.0019 0.0236 0.0268
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0019 0.0236 0.0236
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.003 0.0878 0.0878
Loa Loa (eye worm) hypothetical protein 0.0019 0.0236 0.0268
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0878 0.0996
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0019 0.0236 0.0236
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0019 0.0236 0.0236
Brugia malayi excitatory GABA receptor EXP-1A 0.0019 0.0236 0.0268
Loa Loa (eye worm) hypothetical protein 0.0019 0.0236 0.0268
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0015 0 0.5
Echinococcus granulosus glycine receptor subunit beta 0.0019 0.0236 0.0236
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0034 0.0034
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0878 0.0996
Echinococcus multilocularis lamin 0.0029 0.0825 0.0825
Loa Loa (eye worm) hypothetical protein 0.0019 0.0236 0.0268
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0034 0.0038
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0019 0.0236 0.0236
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0878 0.0878
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.003 0.0878 0.0878
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0825 0.0936
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0019 0.0236 0.0236
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.003 0.0878 0.0878
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0019 0.0236 0.0236
Echinococcus granulosus FTZ F1 alpha 0.003 0.0878 0.0878
Echinococcus granulosus intermediate filament protein 0.0029 0.0825 0.0825
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0019 0.0236 0.0236
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0104 0.0104
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0025 0.0564 1
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0104 0.0118
Brugia malayi ecdysteroid receptor 0.003 0.0878 0.0996
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.003 0.0878 0.0878
Schistosoma mansoni hypothetical protein 0.0017 0.0104 0.0104
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0712 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0236 0.0268
Loa Loa (eye worm) hypothetical protein 0.0027 0.0712 0.0807
Schistosoma mansoni intermediate filament proteins 0.0029 0.0825 0.0825
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.003 0.0878 0.0878
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0825 0.0936
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0104 0.0104
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.003 0.0878 0.0996
Schistosoma mansoni nAChR subunit 0.0019 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.003 0.0878 0.0996
Schistosoma mansoni Tr4/Tr2 (homologue) 0.003 0.0878 0.0878
Loa Loa (eye worm) hypothetical protein 0.003 0.0878 0.0996
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.2299 0.2606
Echinococcus multilocularis GPCR, family 2 0.0017 0.0104 0.0104
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0236 0.0268
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0015 0 0.5
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.2299 0.2606
Loa Loa (eye worm) hypothetical protein 0.0016 0.0034 0.0038
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0236 0.0268
Schistosoma mansoni hypothetical protein 0.0185 1 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0236 0.0268
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0019 0.0236 0.0268
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0564 0.7928
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0564 0.064
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0019 0.0236 0.0268
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0878 0.0878
Mycobacterium leprae putative cytochrome p450 0.0015 0 0.5
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.003 0.0878 0.0996
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0019 0.0236 0.0268
Schistosoma mansoni thyroid hormone receptor 0.003 0.0878 0.0878
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0019 0.0236 0.0268
Loa Loa (eye worm) hypothetical protein 0.0019 0.0236 0.0268
Loa Loa (eye worm) hypothetical protein 0.0037 0.1283 0.1455
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0019 0.0236 0.0236
Brugia malayi Cation transporter family protein 0.0019 0.0236 0.0268
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0019 0.0236 0.0236
Schistosoma mansoni nAChR subunit 0.0019 0.0236 0.0236
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.003 0.0878 0.0878
Trypanosoma brucei cytochrome P450, putative 0.0025 0.0564 0.7928
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0015 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0054 0.2299 0.2606
Onchocerca volvulus 0.0072 0.3335 0.361
Leishmania major cytochrome p450-like protein 0.0025 0.0564 0.7928
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0019 0.0236 0.0236
Schistosoma mansoni hypothetical protein 0.0017 0.0104 0.0104
Echinococcus multilocularis jun protein 0.0092 0.4496 0.4496
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0019 0.0236 0.0236
Loa Loa (eye worm) hypothetical protein 0.0029 0.0793 0.0899
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.003 0.0878 0.0878
Brugia malayi Nuclear hormone receptor family member nhr-25 0.003 0.0878 0.0996
Brugia malayi hypothetical protein 0.0016 0.0034 0.0038
Loa Loa (eye worm) hypothetical protein 0.003 0.0878 0.0996
Echinococcus multilocularis nAChR subunit 0.0019 0.0236 0.0236
Echinococcus multilocularis FTZ F1 alpha 0.003 0.0878 0.0878
Loa Loa (eye worm) ACC-1 protein 0.0019 0.0236 0.0268
Leishmania major hypothetical protein, conserved 0.0027 0.0712 1
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0019 0.0236 0.0236
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0019 0.0236 0.0268
Loa Loa (eye worm) hypothetical protein 0.0019 0.0236 0.0268
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0015 0 0.5
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0015 0 0.5
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0712 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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