Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.162 | 0.3276 | 0.3276 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.091 | 0.1735 | 0.1735 |
Entamoeba histolytica | hypothetical protein | 0.0314 | 0.0442 | 0.0324 |
Entamoeba histolytica | hypothetical protein | 0.0314 | 0.0442 | 0.0324 |
Trypanosoma brucei | phosphatidylinositol kinase related protein, putative | 0.091 | 0.1735 | 0.1633 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.161 | 0.3253 | 0.317 |
Schistosoma mansoni | hypothetical protein | 0.0314 | 0.0442 | 0.042 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.3762 | 0.7923 | 0.7897 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.0314 | 0.0442 | 0.0324 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2567 | 0.533 | 0.5273 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP1A | 0.0167 | 0.0122 | 0.0122 |
Schistosoma mansoni | phosphatidylinositol 3-kinase class | 0.0314 | 0.0442 | 0.042 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0596 | 0.1053 | 0.0943 |
Echinococcus multilocularis | Phosphatidylinositol 4 kinase type 2 beta | 0.0314 | 0.0442 | 0.0442 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2563 | 0.5322 | 0.5264 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0314 | 0.0442 | 0.0442 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.4719 | 1 | 1 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 | 0.0167 | 0.0122 | 0.0122 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.0501 | 0.0847 | 0.0735 |
Plasmodium vivax | hypothetical protein | 0.0314 | 0.0442 | 0.8837 |
Giardia lamblia | Phosphoinositide-3-kinase, catalytic, alpha polypeptide | 0.0402 | 0.0631 | 0.0516 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP4 | 0.0167 | 0.0122 | 0.0122 |
Echinococcus multilocularis | peptidyl prolyl cis trans isomerase FKBP4 | 0.0167 | 0.0122 | 0.0122 |
Echinococcus granulosus | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0433 | 0.07 | 0.07 |
Echinococcus multilocularis | serine:threonine protein kinase SMG1 | 0.091 | 0.1735 | 0.1735 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0334 | 0.0484 | 0.0463 |
Echinococcus multilocularis | DNA dependent protein kinase catalytic subunit | 0.0566 | 0.0988 | 0.0988 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.091 | 0.1735 | 0.1633 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.352 | 0.7399 | 0.7367 |
Schistosoma mansoni | immunophilin FK506 binding protein FKBP12 | 0.0167 | 0.0122 | 0.01 |
Echinococcus multilocularis | Zinc finger, PHD finger | 0.0334 | 0.0484 | 0.0484 |
Leishmania major | phosphatidylinositol 4-kinase alpha, putative | 0.0334 | 0.0484 | 0.0367 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0314 | 0.0442 | 0.5 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.4719 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.161 | 0.3253 | 0.317 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0632 | 0.113 | 0.113 |
Leishmania major | phosphatidylinositol kinase, putative | 0.0314 | 0.0442 | 0.0324 |
Trichomonas vaginalis | phosphatidylinositol 4-kinase, putative | 0.0334 | 0.0484 | 0.0367 |
Echinococcus granulosus | PIK kinase FAT and Armadillo domain containing protein | 0.0699 | 0.1277 | 0.1277 |
Entamoeba histolytica | Phosphatidylinositol 3- and 4-kinase family | 0.0921 | 0.1758 | 0.1657 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.161 | 0.3253 | 0.317 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0314 | 0.0442 | 0.0324 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.1971 | 0.4037 | 0.3963 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.0441 | 0.0716 | 0.0602 |
Plasmodium falciparum | phosphatidylinositol 3-kinase | 0.0334 | 0.0484 | 1 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.4719 | 1 | 1 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase vps34-like | 0.0373 | 0.0569 | 0.0453 |
Loa Loa (eye worm) | phosphatidylinositol kinase | 0.0314 | 0.0442 | 0.0442 |
Brugia malayi | phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative | 0.017 | 0.0128 | 0.0128 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit gamma, putative | 0.0501 | 0.0847 | 0.0735 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0314 | 0.0442 | 0.0442 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.0501 | 0.0847 | 0.0735 |
Entamoeba histolytica | protein kinase rad3, putative | 0.091 | 0.1735 | 0.1633 |
Echinococcus granulosus | phosphatidylinositol 45 bisphosphate 3 kinase | 0.0671 | 0.1216 | 0.1216 |
Onchocerca volvulus | 0.0314 | 0.0442 | 0.5 | |
Toxoplasma gondii | non-specific serine/threonine protein kinase | 0.1014 | 0.196 | 0.2182 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.3765 | 0.7931 | 0.7906 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.4719 | 1 | 1 |
Schistosoma mansoni | immunophilin | 0.0144 | 0.0072 | 0.005 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.352 | 0.7399 | 0.7367 |
Giardia lamblia | Phosphatidylinositol 4-kinase | 0.0314 | 0.0442 | 0.0324 |
Plasmodium falciparum | phosphatidylinositol 3- and 4-kinase, putative | 0.0314 | 0.0442 | 0.8837 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2563 | 0.5322 | 0.5264 |
Echinococcus multilocularis | 0.0314 | 0.0442 | 0.0442 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.352 | 0.7399 | 0.7367 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2821 | 0.5881 | 0.583 |
Toxoplasma gondii | phosphatidylinositol 3- and 4-kinase | 0.0334 | 0.0484 | 0.0061 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.1659 | 0.3361 | 0.3279 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase, putative | 0.0314 | 0.0442 | 0.0324 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.352 | 0.7399 | 0.7367 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.091 | 0.1735 | 0.1633 |
Trypanosoma brucei | phosphatidylinositol 3-kinase catalytic subunit, putative | 0.0314 | 0.0442 | 0.0324 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.4719 | 1 | 1 |
Schistosoma mansoni | phosphatidylinositol 4-kinase | 0.0334 | 0.0484 | 0.0463 |
Echinococcus granulosus | phosphatidylinositol 4 kinase beta | 0.0314 | 0.0442 | 0.0442 |
Loa Loa (eye worm) | phosphatidylinositol 4-kinase type 3 alpha isoform 1 | 0.0334 | 0.0484 | 0.0484 |
Trypanosoma brucei | phosphatidylinositol 4-kinase alpha, putative | 0.0334 | 0.0484 | 0.0367 |
Plasmodium vivax | phosphatidylinositol 3- and 4-kinase, putative | 0.0314 | 0.0442 | 0.8837 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0314 | 0.0442 | 0.0442 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.352 | 0.7399 | 0.7367 |
Mycobacterium ulcerans | FK-506 binding protein, peptidyl-prolyl cis-trans isomerase | 0.0167 | 0.0122 | 0.5 |
Toxoplasma gondii | FATC domain-containing protein | 0.091 | 0.1735 | 0.1859 |
Plasmodium vivax | phosphatidylinositol 4-kinase, putative | 0.0314 | 0.0442 | 0.8837 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.3165 | 0.6629 | 0.6588 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.352 | 0.7399 | 0.7367 |
Echinococcus granulosus | Phosphatidylinositol 4 kinase type 2 beta | 0.0314 | 0.0442 | 0.0442 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.3765 | 0.7931 | 0.7906 |
Schistosoma mansoni | hypothetical protein | 0.0699 | 0.1277 | 0.1258 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.0072 | 0.0072 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0921 | 0.1758 | 0.1657 |
Schistosoma mansoni | phosphatidylinositol 4-kinase type-II | 0.0314 | 0.0442 | 0.042 |
Leishmania major | hypothetical protein, unknown function | 0.0314 | 0.0442 | 0.0324 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0501 | 0.0847 | 0.0847 |
Loa Loa (eye worm) | hypothetical protein | 0.0699 | 0.1277 | 0.1277 |
Giardia lamblia | Hypothetical protein | 0.0314 | 0.0442 | 0.0324 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.4719 | 1 | 1 |
Schistosoma mansoni | immunophilin | 0.0167 | 0.0122 | 0.01 |
Loa Loa (eye worm) | hypothetical protein | 0.1014 | 0.196 | 0.196 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.4719 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.4719 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0433 | 0.07 | 0.07 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.0373 | 0.0569 | 0.0453 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.0442 | 0.0442 |
Leishmania major | phosphatidylinositol kinase related protein, putative | 0.0314 | 0.0442 | 0.0324 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0462 | 0.0762 | 0.0648 |
Loa Loa (eye worm) | hypothetical protein | 0.0596 | 0.1053 | 0.1053 |
Loa Loa (eye worm) | FKBP5 protein | 0.0167 | 0.0122 | 0.0122 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2563 | 0.5322 | 0.5264 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0314 | 0.0442 | 0.0442 |
Entamoeba histolytica | phosphatidylinositol 3-kinase 3, putative | 0.0314 | 0.0442 | 0.0324 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2808 | 0.5854 | 0.5803 |
Brugia malayi | FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 | 0.0167 | 0.0122 | 0.0122 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0373 | 0.0569 | 0.0453 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.3765 | 0.7931 | 0.7906 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0501 | 0.0847 | 0.0735 |
Echinococcus multilocularis | phosphatidylinositol 4 kinase alpha | 0.0334 | 0.0484 | 0.0484 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0671 | 0.1216 | 0.1196 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2821 | 0.5881 | 0.583 |
Echinococcus multilocularis | PIK kinase, FAT and Armadillo domain containing protein | 0.0699 | 0.1277 | 0.1277 |
Brugia malayi | phosphatidylinositol 4-kinase, catalytic, alpha polypeptide | 0.0334 | 0.0484 | 0.0484 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0314 | 0.0442 | 0.0324 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0314 | 0.0442 | 0.0324 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.3762 | 0.7923 | 0.7897 |
Trichomonas vaginalis | phopsphatidylinositol 3-kinase, drosophila, putative | 0.0501 | 0.0847 | 0.0735 |
Echinococcus granulosus | serine protein kinase ATM | 0.091 | 0.1735 | 0.1735 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.0373 | 0.0569 | 0.0453 |
Plasmodium falciparum | phosphatidylinositol 4-kinase | 0.0314 | 0.0442 | 0.8837 |
Onchocerca volvulus | 0.0314 | 0.0442 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.091 | 0.1735 | 0.1735 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.4719 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.352 | 0.7399 | 0.7367 |
Entamoeba histolytica | hypothetical protein | 0.0462 | 0.0762 | 0.0648 |
Echinococcus granulosus | peptidyl prolyl cis trans isomerase FKBP4 | 0.0144 | 0.0072 | 0.0072 |
Plasmodium vivax | hypothetical protein, conserved | 0.0314 | 0.0442 | 0.8837 |
Toxoplasma gondii | phosphatidylinositol 3- and 4-kinase | 0.0334 | 0.0484 | 0.0061 |
Echinococcus granulosus | DNA dependent protein kinase catalytic subunit | 0.0566 | 0.0988 | 0.0988 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0314 | 0.0442 | 0.0442 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2567 | 0.533 | 0.5273 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.091 | 0.1735 | 0.1735 |
Echinococcus multilocularis | serine protein kinase ATM | 0.091 | 0.1735 | 0.1735 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.1659 | 0.3361 | 0.3361 |
Schistosoma mansoni | phosphatidylinositol 4-kinase | 0.0314 | 0.0442 | 0.042 |
Echinococcus granulosus | serine:threonine protein kinase SMG1 | 0.091 | 0.1735 | 0.1735 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.3762 | 0.7923 | 0.7897 |
Trypanosoma cruzi | phosphatidylinositol 4-kinase, putative | 0.0314 | 0.0442 | 0.0324 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.161 | 0.3253 | 0.317 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.4719 | 1 | 1 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.1659 | 0.3361 | 0.3346 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0699 | 0.1277 | 0.117 |
Leishmania major | hypothetical protein, conserved | 0.0404 | 0.0635 | 0.052 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.1659 | 0.3361 | 0.3279 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0314 | 0.0442 | 0.0442 |
Trypanosoma cruzi | phosphatidylinositol 4-kinase alpha, putative | 0.0334 | 0.0484 | 0.0367 |
Entamoeba histolytica | phosphatidylinositol 3-kinase 1, putative | 0.0187 | 0.0165 | 0.0044 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.4719 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1014 | 0.196 | 0.1861 |
Trypanosoma cruzi | phosphatidylinositol 4-kinase, putative | 0.0314 | 0.0442 | 0.0324 |
Schistosoma mansoni | immunophilin | 0.0167 | 0.0122 | 0.01 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0394 | 0.0615 | 0.0499 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0433 | 0.07 | 0.07 |
Giardia lamblia | GTOR | 0.4719 | 1 | 1 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0373 | 0.0569 | 0.0569 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.091 | 0.1735 | 0.1633 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0373 | 0.0569 | 0.0453 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.1659 | 0.3361 | 0.3361 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2821 | 0.5881 | 0.583 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.161 | 0.3253 | 0.317 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.1659 | 0.3361 | 0.3361 |
Loa Loa (eye worm) | FKBP-type peptidyl-prolyl cis-trans isomerase-12 | 0.0167 | 0.0122 | 0.0122 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm) | 0.091 | 0.1735 | 0.1717 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.4719 | 1 | 1 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative | 0.0373 | 0.0569 | 0.0453 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.162 | 0.3276 | 0.3193 |
Giardia lamblia | Phosphoinositide-3-kinase, class 3 | 0.0354 | 0.0527 | 0.041 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.4719 | 1 | 1 |
Echinococcus multilocularis | peptidyl prolyl cis trans isomerase FKBP4 | 0.0144 | 0.0072 | 0.0072 |
Trichomonas vaginalis | phopsphatidylinositol 3-kinase, drosophila, putative | 0.0314 | 0.0442 | 0.0324 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2808 | 0.5854 | 0.5803 |
Echinococcus granulosus | phosphatidylinositol 3 kinase catalytic subunit | 0.0334 | 0.0484 | 0.0484 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1267 | 0.251 | 0.2418 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative | 0.0441 | 0.0716 | 0.0602 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.161 | 0.3253 | 0.317 |
Treponema pallidum | peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) | 0.0167 | 0.0122 | 0.5 |
Echinococcus multilocularis | phosphatidylinositol 4,5 bisphosphate 3 kinase | 0.0671 | 0.1216 | 0.1216 |
Loa Loa (eye worm) | hypothetical protein | 0.0953 | 0.1828 | 0.1828 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0596 | 0.1053 | 0.0943 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.3062 | 0.6405 | 0.6361 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0314 | 0.0442 | 0.0324 |
Echinococcus multilocularis | fk506 binding protein | 0.0167 | 0.0122 | 0.0122 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.0334 | 0.0484 | 0.0367 |
Mycobacterium leprae | conserved hypothetical protein | 0.0314 | 0.0442 | 0.5 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0373 | 0.0569 | 0.0453 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.4719 | 1 | 1 |
Plasmodium vivax | phosphatidylinositol 3-kinase, putative | 0.0334 | 0.0484 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2567 | 0.533 | 0.5273 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0596 | 0.1053 | 0.0943 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.352 | 0.7399 | 1 |
Schistosoma mansoni | fkbp-rapamycin associated protein | 0.091 | 0.1735 | 0.1717 |
Entamoeba histolytica | hypothetical protein | 0.091 | 0.1735 | 0.1633 |
Echinococcus multilocularis | Phosphatidylinositol 4 kinase type 2 beta | 0.0314 | 0.0442 | 0.0442 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0314 | 0.0442 | 0.0442 |
Plasmodium vivax | phosphatidylinositol 4-kinase, putative | 0.0314 | 0.0442 | 0.8837 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2567 | 0.533 | 0.5273 |
Brugia malayi | FAT domain containing protein | 0.0699 | 0.1277 | 0.1277 |
Entamoeba histolytica | phosphatidylinositol 4-kinase, putative | 0.0334 | 0.0484 | 0.0367 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.3762 | 0.7923 | 0.7897 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0373 | 0.0569 | 0.0548 |
Entamoeba histolytica | hypothetical protein | 0.0314 | 0.0442 | 0.0324 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase, putative | 0.091 | 0.1735 | 0.1633 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.162 | 0.3276 | 0.3193 |
Trypanosoma cruzi | phosphatidylinositol 4-kinase alpha, putative | 0.0334 | 0.0484 | 0.0367 |
Entamoeba histolytica | phosphatidylinositol-4,5-bisphosphate 3-kinase, putative | 0.0334 | 0.0484 | 0.0367 |
Echinococcus granulosus | Phosphatidylinositol 4 kinase type 2 beta | 0.0314 | 0.0442 | 0.0442 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.4019 | 0.8482 | 0.8463 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.0334 | 0.0484 | 0.0367 |
Leishmania major | phosphatidylinositol 3-related kinase, putative | 0.162 | 0.3276 | 0.3193 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.4719 | 1 | 1 |
Echinococcus granulosus | phosphatidylinositol 4 kinase alpha | 0.0334 | 0.0484 | 0.0484 |
Echinococcus multilocularis | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0433 | 0.07 | 0.07 |
Leishmania major | phosphatidylinositol 4-kinase, putative | 0.0314 | 0.0442 | 0.0324 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.0501 | 0.0847 | 0.0735 |
Trypanosoma cruzi | phosphatidylinositol kinase, putative | 0.0314 | 0.0442 | 0.0324 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.3762 | 0.7923 | 0.7897 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.2225 | 0.4587 | 0.4521 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.0334 | 0.0484 | 0.0367 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 36.7 uM | In vitro inhibition of Collagen (10 ug/mL) induced platelet aggregatory activity. | ChEMBL. | 12873516 |
IC50 (functional) | = 59.2 uM | Inhibitory concentration required against Archidonic acid (100 uM) induced platelet aggregatory activity | ChEMBL. | 12873516 |
Inhibition (functional) | = 26 % | Percentage inhibition against thrombin induced platelet aggregatory activity | ChEMBL. | 12873516 |
Inhibition (functional) | = 52 % | Percentage inhibition against platelet activating factor (2 ng/mL) induced platelet aggregatory activity | ChEMBL. | 12873516 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.