Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.028 | 0.0854 | 0.0854 |
Loa Loa (eye worm) | hypothetical protein | 0.0269 | 0.0803 | 0.0777 |
Loa Loa (eye worm) | phosphatidylinositol kinase | 0.0151 | 0.0232 | 0.0205 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.1026 | 0.4437 | 0.4421 |
Echinococcus granulosus | phosphatidylinositol 4 kinase alpha | 0.017 | 0.0325 | 0.0298 |
Brugia malayi | phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative | 0.0169 | 0.0321 | 0.0294 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1746 | 0.7894 | 0.7894 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1855 | 0.8421 | 0.8421 |
Loa Loa (eye worm) | phosphatidylinositol 4-kinase type 3 alpha isoform 1 | 0.017 | 0.0325 | 0.0298 |
Brugia malayi | phosphatidylinositol 4-kinase, catalytic, alpha polypeptide | 0.017 | 0.0325 | 0.0298 |
Leishmania major | phosphatidylinositol kinase related protein, putative | 0.0151 | 0.0232 | 0.0205 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2184 | 1 | 1 |
Echinococcus multilocularis | Zinc finger, PHD finger | 0.017 | 0.0325 | 0.0298 |
Plasmodium falciparum | phosphatidylinositol 3-kinase | 0.017 | 0.0325 | 1 |
Leishmania major | phosphatidylinositol 3-related kinase, putative | 0.077 | 0.3209 | 0.319 |
Schistosoma mansoni | phosphatidylinositol 4-kinase type-II | 0.0151 | 0.0232 | 0.0205 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1746 | 0.7894 | 0.7894 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0431 | 0.1579 | 0.1555 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1198 | 0.5264 | 0.5264 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative | 0.0209 | 0.0514 | 0.0514 |
Toxoplasma gondii | phosphatidylinositol 3- and 4-kinase | 0.017 | 0.0325 | 0.013 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.077 | 0.3209 | 0.319 |
Schistosoma mansoni | phosphatidylinositol 3-kinase class | 0.0151 | 0.0232 | 0.0205 |
Entamoeba histolytica | hypothetical protein | 0.0431 | 0.1579 | 0.1555 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1198 | 0.5264 | 0.5264 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1635 | 0.7362 | 0.7362 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.0337 | 0.1128 | 0.1103 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0209 | 0.0514 | 0.0487 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.2184 | 1 | 1 |
Echinococcus multilocularis | Phosphatidylinositol 4 kinase type 2 beta | 0.0151 | 0.0232 | 0.0205 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.017 | 0.0325 | 0.0298 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0151 | 0.0232 | 0.0205 |
Loa Loa (eye worm) | hypothetical protein | 0.0437 | 0.1606 | 0.1583 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0151 | 0.0232 | 0.0205 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0467 | 0.1752 | 0.1729 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.076 | 0.3158 | 0.3139 |
Schistosoma mansoni | voltage-gated potassium channel | 0.012 | 0.0083 | 0.0055 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative | 0.0277 | 0.0839 | 0.0839 |
Echinococcus granulosus | PIK kinase FAT and Armadillo domain containing protein | 0.0329 | 0.1088 | 0.1063 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1417 | 0.6314 | 0.6314 |
Trichomonas vaginalis | conserved hypothetical protein | 0.048 | 0.1812 | 0.1812 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0151 | 0.0232 | 0.0205 |
Entamoeba histolytica | phosphatidylinositol-4,5-bisphosphate 3-kinase, putative | 0.017 | 0.0325 | 0.0298 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.011 | 0.0035 | 0.0007 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase catalytic subunit gamma, putative | 0.0337 | 0.1128 | 0.1128 |
Plasmodium vivax | phosphatidylinositol 3-kinase, putative | 0.017 | 0.0325 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0587 | 0.233 | 0.233 |
Giardia lamblia | Hypothetical protein | 0.0151 | 0.0232 | 0.0205 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1306 | 0.5783 | 0.5783 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.2184 | 1 | 1 |
Giardia lamblia | Phosphoinositide-3-kinase, class 3 | 0.019 | 0.0421 | 0.0394 |
Entamoeba histolytica | Phosphatidylinositol 3- and 4-kinase family | 0.0441 | 0.1629 | 0.1606 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.2184 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.077 | 0.3209 | 0.3209 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0209 | 0.0514 | 0.0487 |
Echinococcus granulosus | serine:threonine protein kinase SMG1 | 0.0431 | 0.1579 | 0.1555 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0209 | 0.0514 | 0.0487 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0209 | 0.0514 | 0.0487 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.2184 | 1 | 1 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0809 | 0.3395 | 0.3377 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.011 | 0.0035 | 0.0007 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0809 | 0.3395 | 0.3377 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1309 | 0.5796 | 0.5796 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.076 | 0.3158 | 0.3158 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.2184 | 1 | 1 |
Echinococcus granulosus | Phosphatidylinositol 4 kinase type 2 beta | 0.0151 | 0.0232 | 0.0205 |
Echinococcus multilocularis | phosphatidylinositol 4,5 bisphosphate 3 kinase | 0.0506 | 0.194 | 0.1917 |
Echinococcus multilocularis | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0269 | 0.0803 | 0.0777 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0151 | 0.0232 | 0.5 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.011 | 0.0035 | 0.0007 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.023 | 0.0614 | 0.0588 |
Echinococcus granulosus | DNA dependent protein kinase catalytic subunit | 0.0402 | 0.1438 | 0.1415 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0809 | 0.3395 | 0.3377 |
Leishmania major | hypothetical protein, conserved | 0.024 | 0.066 | 0.0634 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0809 | 0.3395 | 0.3377 |
Plasmodium vivax | phosphatidylinositol 4-kinase, putative | 0.0151 | 0.0232 | 0.6879 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.017 | 0.0325 | 0.0298 |
Trypanosoma brucei | phosphatidylinositol 3-kinase catalytic subunit, putative | 0.0151 | 0.0232 | 0.0205 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0809 | 0.3395 | 0.3377 |
Trypanosoma brucei | phosphatidylinositol kinase related protein, putative | 0.0431 | 0.1579 | 0.1555 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.076 | 0.3158 | 0.3139 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.2184 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1746 | 0.7894 | 0.7894 |
Echinococcus granulosus | serine protein kinase ATM | 0.0431 | 0.1579 | 0.1555 |
Onchocerca volvulus | 0.0151 | 0.0232 | 0.5 | |
Echinococcus multilocularis | phosphatidylinositol 4 kinase alpha | 0.017 | 0.0325 | 0.0298 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2184 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.028 | 0.0854 | 0.0854 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.1635 | 0.7362 | 1 |
Echinococcus granulosus | phosphatidylinositol 4 kinase beta | 0.0151 | 0.0232 | 0.0205 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase, putative | 0.0431 | 0.1579 | 0.1555 |
Giardia lamblia | Phosphatidylinositol 4-kinase | 0.0151 | 0.0232 | 0.0205 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1198 | 0.5264 | 0.5264 |
Brugia malayi | FAT domain containing protein | 0.0329 | 0.1088 | 0.1063 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 0.1088 | 0.1063 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0431 | 0.1579 | 0.1555 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0209 | 0.0514 | 0.0487 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.0151 | 0.0232 | 0.0232 |
Schistosoma mansoni | hypothetical protein | 0.0151 | 0.0232 | 0.0205 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1746 | 0.7894 | 0.7894 |
Leishmania major | phosphatidylinositol kinase, putative | 0.0151 | 0.0232 | 0.0205 |
Entamoeba histolytica | protein kinase rad3, putative | 0.0431 | 0.1579 | 0.1555 |
Plasmodium vivax | phosphatidylinositol 3- and 4-kinase, putative | 0.0151 | 0.0232 | 0.6879 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.1747 | 0.7902 | 0.7896 |
Entamoeba histolytica | hypothetical protein | 0.0298 | 0.0939 | 0.0914 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1306 | 0.5783 | 0.5783 |
Echinococcus multilocularis | serine:threonine protein kinase SMG1 | 0.0431 | 0.1579 | 0.1555 |
Schistosoma mansoni | phosphatidylinositol 4-kinase | 0.017 | 0.0325 | 0.0298 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.017 | 0.0325 | 0.0325 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase 2, putative | 0.0337 | 0.1128 | 0.1103 |
Schistosoma mansoni | voltage-gated potassium channel | 0.012 | 0.0083 | 0.0055 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1196 | 0.5256 | 0.5256 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.028 | 0.0854 | 0.0829 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0337 | 0.1128 | 0.1103 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.0209 | 0.0514 | 0.0514 |
Plasmodium falciparum | phosphatidylinositol 3- and 4-kinase, putative | 0.0151 | 0.0232 | 0.6879 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1306 | 0.5783 | 0.5783 |
Schistosoma mansoni | phosphatidylinositol 4-kinase | 0.0151 | 0.0232 | 0.0205 |
Trichomonas vaginalis | fk506-binding protein, putative | 0.0108 | 0.0028 | 0.0028 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.2184 | 1 | 1 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.2184 | 1 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0151 | 0.0232 | 0.6879 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0269 | 0.0803 | 0.0777 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.0209 | 0.0514 | 0.0514 |
Trypanosoma cruzi | phosphatidylinositol 4-kinase alpha, putative | 0.017 | 0.0325 | 0.0298 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0151 | 0.0232 | 0.0205 |
Entamoeba histolytica | phosphatidylinositol 3-kinase, putative | 0.0298 | 0.0939 | 0.0914 |
Trichomonas vaginalis | phopsphatidylinositol 3-kinase, drosophila, putative | 0.0151 | 0.0232 | 0.0232 |
Loa Loa (eye worm) | hypothetical protein | 0.048 | 0.1812 | 0.1789 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.2184 | 1 | 1 |
Treponema pallidum | peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) | 0.0108 | 0.0028 | 0.5 |
Echinococcus granulosus | phosphatidylinositol 45 bisphosphate 3 kinase | 0.0506 | 0.194 | 0.1917 |
Loa Loa (eye worm) | hypothetical protein | 0.0431 | 0.1579 | 0.1555 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase, putative | 0.0151 | 0.0232 | 0.0205 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1465 | 0.6548 | 0.6548 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1635 | 0.7362 | 0.7362 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0151 | 0.0232 | 0.0232 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0431 | 0.1579 | 0.1555 |
Trichomonas vaginalis | immunophilin, putative | 0.0108 | 0.0028 | 0.0028 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm) | 0.0431 | 0.1579 | 0.1555 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.1747 | 0.7902 | 0.7896 |
Trypanosoma cruzi | phosphatidylinositol kinase, putative | 0.0151 | 0.0232 | 0.0205 |
Entamoeba histolytica | hypothetical protein | 0.0151 | 0.0232 | 0.0205 |
Entamoeba histolytica | hypothetical protein | 0.0151 | 0.0232 | 0.0205 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1635 | 0.7362 | 0.7362 |
Echinococcus multilocularis | Phosphatidylinositol 4 kinase type 2 beta | 0.0151 | 0.0232 | 0.0205 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.017 | 0.0325 | 0.0325 |
Giardia lamblia | GTOR | 0.2184 | 1 | 1 |
Entamoeba histolytica | phosphatidylinositol 3-kinase 1, putative | 0.0186 | 0.0403 | 0.0377 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0809 | 0.3395 | 0.3377 |
Toxoplasma gondii | FATC domain-containing protein | 0.0431 | 0.1579 | 0.1888 |
Mycobacterium leprae | conserved hypothetical protein | 0.0151 | 0.0232 | 0.5 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1635 | 0.7362 | 0.7362 |
Trypanosoma cruzi | phosphatidylinositol 4-kinase, putative | 0.0151 | 0.0232 | 0.0205 |
Echinococcus granulosus | phosphatidylinositol 3 kinase catalytic subunit | 0.017 | 0.0325 | 0.0298 |
Trypanosoma cruzi | phosphatidylinositol 4-kinase alpha, putative | 0.017 | 0.0325 | 0.0298 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0151 | 0.0232 | 0.0205 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1635 | 0.7362 | 0.7362 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1309 | 0.5796 | 0.5796 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1635 | 0.7362 | 0.7362 |
Echinococcus multilocularis | 0.0151 | 0.0232 | 0.0205 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1196 | 0.5256 | 0.5256 |
Onchocerca volvulus | 0.0151 | 0.0232 | 0.5 | |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.1747 | 0.7902 | 0.7896 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.2184 | 1 | 1 |
Schistosoma mansoni | phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K | 0.0506 | 0.194 | 0.1917 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 0.0854 | 0.0829 |
Echinococcus granulosus | Phosphatidylinositol 4 kinase type 2 beta | 0.0151 | 0.0232 | 0.0205 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0441 | 0.1629 | 0.1629 |
Schistosoma mansoni | hypothetical protein | 0.0329 | 0.1088 | 0.1063 |
Entamoeba histolytica | hypothetical protein | 0.0151 | 0.0232 | 0.0205 |
Plasmodium vivax | phosphatidylinositol 4-kinase, putative | 0.0151 | 0.0232 | 0.6879 |
Trichomonas vaginalis | phopsphatidylinositol 3-kinase, drosophila, putative | 0.0337 | 0.1128 | 0.1128 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.2184 | 1 | 1 |
Toxoplasma gondii | phosphatidylinositol 3- and 4-kinase | 0.017 | 0.0325 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.0232 | 0.0205 |
Trypanosoma cruzi | phosphatidylinositol 3-kinase vps34-like | 0.0209 | 0.0514 | 0.0487 |
Entamoeba histolytica | phosphatidylinositol 4-kinase, putative | 0.017 | 0.0325 | 0.0298 |
Echinococcus multilocularis | DNA dependent protein kinase catalytic subunit | 0.0402 | 0.1438 | 0.1415 |
Toxoplasma gondii | non-specific serine/threonine protein kinase | 0.048 | 0.1812 | 0.2215 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.076 | 0.3158 | 0.3158 |
Trichomonas vaginalis | phosphatidylinositol 3-kinase class, putative | 0.0277 | 0.0839 | 0.0839 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.0918 | 0.3918 | 0.3901 |
Plasmodium falciparum | phosphatidylinositol 4-kinase | 0.0151 | 0.0232 | 0.6879 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0151 | 0.0232 | 0.0232 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.2184 | 1 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.076 | 0.3158 | 0.3158 |
Leishmania major | phosphatidylinositol 4-kinase alpha, putative | 0.017 | 0.0325 | 0.0298 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0151 | 0.0232 | 0.0205 |
Trichomonas vaginalis | phosphatidylinositol kinase, putative | 0.0337 | 0.1128 | 0.1128 |
Echinococcus multilocularis | PIK kinase, FAT and Armadillo domain containing protein | 0.0329 | 0.1088 | 0.1063 |
Trypanosoma brucei | phosphatidylinositol 4-kinase alpha, putative | 0.017 | 0.0325 | 0.0298 |
Trichomonas vaginalis | peptidylprolyl isomerase, putative | 0.0108 | 0.0028 | 0.0028 |
Trichomonas vaginalis | phosphatidylinositol 4-kinase, putative | 0.017 | 0.0325 | 0.0325 |
Echinococcus multilocularis | serine protein kinase ATM | 0.0431 | 0.1579 | 0.1555 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1635 | 0.7362 | 0.7362 |
Trichomonas vaginalis | peptidylprolyl isomerase, putative | 0.0108 | 0.0028 | 0.0028 |
Echinococcus granulosus | phosphatidylinositol 4 phosphate 3 kinase C2 | 0.0269 | 0.0803 | 0.0777 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.011 | 0.0035 | 0.0007 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0329 | 0.1088 | 0.1088 |
Giardia lamblia | Phosphoinositide-3-kinase, catalytic, alpha polypeptide | 0.0238 | 0.065 | 0.0624 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0151 | 0.0232 | 0.0205 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0431 | 0.1579 | 0.1579 |
Leishmania major | phosphatidylinositol 4-kinase, putative | 0.0151 | 0.0232 | 0.0205 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0337 | 0.1128 | 0.1103 |
Leishmania major | hypothetical protein, unknown function | 0.0151 | 0.0232 | 0.0205 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1198 | 0.5264 | 0.5264 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1746 | 0.7894 | 0.7894 |
Mycobacterium ulcerans | FK-506 binding protein, peptidyl-prolyl cis-trans isomerase | 0.0108 | 0.0028 | 0.5 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.1196 | 0.5256 | 0.5256 |
Plasmodium vivax | hypothetical protein | 0.0151 | 0.0232 | 0.6879 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.2184 | 1 | 1 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0151 | 0.0232 | 0.0205 |
Trypanosoma cruzi | phosphatidylinositol 4-kinase, putative | 0.0151 | 0.0232 | 0.0205 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0431 | 0.1579 | 0.1579 |
Entamoeba histolytica | phosphatidylinositol 3-kinase 3, putative | 0.0151 | 0.0232 | 0.0205 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.077 | 0.3209 | 0.319 |
Schistosoma mansoni | fkbp-rapamycin associated protein | 0.0431 | 0.1579 | 0.1555 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.076 | 0.3158 | 0.3158 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0151 | 0.0232 | 0.0205 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -4.214 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HOP-92 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.07 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MDA-N Breast cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the HL-60(TB) Leukemia cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the DU-145 Prostate cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the MALME-3M Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.