TDR Targets

Basic information

Technical information

TDR Targets ID: 1635408
Name: N,N'-bis(2-dimethylaminoethyl)phenazine-1,6-d icarboxamide
MW: 408.497 | Formula: C22H28N6O2
H donors: 2 H acceptors: 4 LogP: 1.26 Rotable bonds: 10
Rule of 5 violations (Lipinski): 1
SMILES: CN(CCNC(=O)c1cccc2c1nc1cccc(c1n2)C(=O)NCCN(C)C)C
InChi: 1S/C22H28N6O2/c1-27(2)13-11-23-21(29)15-7-5-9-17-19(15)25-18-10-6-8-16(20(18)26-17)22(30)24-12-14-28(3)4/h5-10H,11-14H2,1-4H3,(H,23,29)(H,24,30)
InChiKey: QRQPYAACCAOZOD-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

NCI60_028162

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	neuropeptide receptor	0.0131	0.0091	0.0078
Trichomonas vaginalis	phosphatidylinositol kinase, putative	0.0347	0.0556	0.0513
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.0438	0.0754	0.0712
Echinococcus multilocularis	neuropeptide Y receptor	0.0131	0.0091	0.0078
Echinococcus granulosus	phosphatidylinositol 4 phosphate 3 kinase C2	0.0498	0.0882	0.0871
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0131	0.0091	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0317	0.0493	0.045
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0131	0.0091	0.0078
Trypanosoma brucei	Phosphatidylinositol 3-kinase tor1	0.472	1	1
Schistosoma mansoni	myosin xvIII	0.0131	0.0091	0.0078
Echinococcus multilocularis	fmrfamide receptor	0.0131	0.0091	0.0078
Echinococcus multilocularis	somatostatin receptor	0.0131	0.0091	0.0078
Schistosoma mansoni	hypothetical protein	0.0131	0.0091	0.0078
Schistosoma mansoni	apoptosis regulator bax	0.0151	0.0135	0.0123
Trichomonas vaginalis	PIKK family atypical protein kinase	0.472	1	1
Schistosoma mansoni	neuropeptide receptor	0.0131	0.0091	0.0078
Echinococcus granulosus	neuropeptide FF receptor 2	0.0131	0.0091	0.0078
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0131	0.0091	0.0078
Plasmodium vivax	hypothetical protein	0.0317	0.0493	0.8759
Brugia malayi	Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog	0.015	0.0132	0.0087
Trypanosoma cruzi	target of rapamycin kinase 3	0.3767	0.7943	0.7943
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0131	0.0091	0.0046
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Echinococcus multilocularis	g protein coupled receptor	0.0131	0.0091	0.0078
Schistosoma mansoni	opsin-like receptor	0.0131	0.0091	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Echinococcus multilocularis	serine protein kinase ATM	0.0913	0.178	0.177
Schistosoma mansoni	neuropeptide F-like receptor	0.0131	0.0091	0.0078
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3522	0.7413	0.7401
Echinococcus granulosus	rhodopsin orphan GPCR	0.0131	0.0091	0.0078
Schistosoma mansoni	phosphatidylinositol 3-kinase class	0.0317	0.0493	0.0481
Echinococcus granulosus	sex peptide receptor	0.0131	0.0091	0.0078
Echinococcus multilocularis	neuropeptides capa receptor	0.0131	0.0091	0.0078
Schistosoma mansoni	ataxia telangiectasia mutated (atm)	0.0913	0.178	0.177
Echinococcus granulosus	phosphatidylinositol 3 and 4 kinase	0.1662	0.3398	0.339
Trichomonas vaginalis	phosphatidylinositol kinase, putative	0.0406	0.0685	0.0643
Leishmania major	hypothetical protein, unknown function	0.0317	0.0493	0.045
Trypanosoma cruzi	phosphatidylinositol 4-kinase alpha, putative	0.0347	0.0556	0.0556
Entamoeba histolytica	phosphatidylinositol3-kinaseTor2, putative	0.472	1	1
Echinococcus multilocularis	g-protein coupled receptor	0.0131	0.0091	0.0078
Schistosoma mansoni	hypothetical protein	0.0131	0.0091	0.0078
Trichomonas vaginalis	PIKK family atypical protein kinase	0.2565	0.5347	0.5326
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0131	0.0091	0.0078
Trichomonas vaginalis	PIKK family atypical protein kinase	0.2822	0.5903	0.5884
Leishmania major	phosphatidylinositol 4-kinase, putative	0.0317	0.0493	0.045
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0131	0.0091	0.0078
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0131	0.0091	0.0078
Echinococcus granulosus	potassium voltage gated channel subfamily H	0.015	0.0132	0.0119
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Echinococcus granulosus	tm gpcr rhodopsin	0.0131	0.0091	0.0078
Leishmania major	target of rapamycin kinase (TOR) kinase 3	0.3767	0.7943	0.7933
Echinococcus granulosus	neuropeptides capa receptor	0.0131	0.0091	0.0078
Trypanosoma cruzi	peptidyl-prolyl cis-trans isomerase, putative	0.011	0.0045	0.0045
Schistosoma mansoni	hypothetical protein	0.0699	0.1318	0.1307
Loa Loa (eye worm)	phosphatidylinositol 3	0.0317	0.0493	0.0493
Echinococcus multilocularis	dro:myosuppressin receptor	0.0131	0.0091	0.0078
Schistosoma mansoni	amine GPCR	0.0131	0.0091	0.0078
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0913	0.178	0.1743
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Echinococcus granulosus	dro:myosuppressin receptor	0.0131	0.0091	0.0078
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.0406	0.0685	0.0643
Entamoeba histolytica	phosphatidylinositol-4,5-bisphosphate 3-kinase, putative	0.0347	0.0556	0.0513
Brugia malayi	larval opioid receptor	0.0131	0.0091	0.0046
Leishmania major	target of rapamycin (TOR) kinase 2, putative	0.472	1	1
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0131	0.0091	0.0091
Loa Loa (eye worm)	hypothetical protein	0.013	0.0089	0.0089
Echinococcus granulosus	Phosphatidylinositol 4 kinase type 2 beta	0.0317	0.0493	0.0481
Trypanosoma brucei	FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative	0.1973	0.4069	0.4042
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1612	0.329	0.326
Echinococcus granulosus	phosphatidylinositol 4 kinase alpha	0.0347	0.0556	0.0544
Brugia malayi	G-protein coupled receptor	0.0131	0.0091	0.0046
Brugia malayi	Serotonin receptor	0.0131	0.0091	0.0046
Echinococcus multilocularis	neuropeptide receptor A26	0.0131	0.0091	0.0078
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0131	0.0091	0.0078
Schistosoma mansoni	opsin-like receptor	0.0131	0.0091	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0103	0.003	0.003
Echinococcus multilocularis	allatostatin A receptor	0.0131	0.0091	0.0078
Echinococcus granulosus	Phosphatidylinositol 4 kinase type 2 beta	0.0317	0.0493	0.0481
Brugia malayi	Serotonin receptor	0.0131	0.0091	0.0046
Brugia malayi	AKH receptor	0.0131	0.0091	0.0046
Brugia malayi	hypothetical protein	0.0131	0.0091	0.0046
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Brugia malayi	hypothetical protein	0.0131	0.0091	0.0046
Brugia malayi	FAT domain containing protein	0.0699	0.1318	0.1279
Giardia lamblia	Phosphoinositide-3-kinase, class 3	0.0377	0.0622	0.0579
Echinococcus multilocularis	neuropeptide s receptor	0.0131	0.0091	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1612	0.329	0.326
Echinococcus granulosus	FKBP12 rapamycin complex associated protein	0.472	1	1
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0131	0.0091	0.0078
Loa Loa (eye worm)	G-protein coupled receptor	0.0131	0.0091	0.0091
Echinococcus multilocularis	Zinc finger, PHD finger	0.0347	0.0556	0.0544
Schistosoma mansoni	hypothetical protein	0.0151	0.0135	0.0123
Echinococcus multilocularis	serotonin receptor	0.0131	0.0091	0.0078
Brugia malayi	G protein-coupled receptor	0.0131	0.0091	0.0046
Echinococcus multilocularis	fmrfamide receptor	0.0131	0.0091	0.0078
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0131	0.0091	0.0046
Echinococcus granulosus	neuropeptide receptor	0.0131	0.0091	0.0078
Echinococcus granulosus	rhodopsin orphan GPCR	0.0131	0.0091	0.0078
Trypanosoma cruzi	phosphatidylinositol kinase, putative	0.0317	0.0493	0.0493
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0131	0.0091	0.0078
Trichomonas vaginalis	phosphatidylinositol kinase, putative	0.06	0.1104	0.1064
Schistosoma mansoni	voltage-gated potassium channel	0.0164	0.0161	0.0149
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0131	0.0091	0.0078
Schistosoma mansoni	neuropeptide receptor	0.0131	0.0091	0.0078
Echinococcus multilocularis	Bcl 2 ous antagonist:killer	0.0151	0.0135	0.0123
Echinococcus multilocularis	neuropeptide receptor	0.0131	0.0091	0.0078
Trypanosoma brucei	phosphatidylinositol 3-kinase catalytic subunit, putative	0.0317	0.0493	0.045
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0131	0.0091	0.0078
Loa Loa (eye worm)	phosphatidylinositol 3	0.472	1	1
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0131	0.0091	0.0078
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0131	0.0091	0.0078
Trichomonas vaginalis	conserved hypothetical protein	0.0699	0.1318	0.1279
Echinococcus granulosus	neuropeptide Y receptor	0.0131	0.0091	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Schistosoma mansoni	amine GPCR	0.0131	0.0091	0.0078
Schistosoma mansoni	phosphatidylinositol 4-kinase type-II	0.0317	0.0493	0.0481
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1612	0.329	0.326
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0131	0.0091	0.0078
Echinococcus granulosus	G protein coupled receptor 139	0.0131	0.0091	0.0078
Echinococcus granulosus	serine protein kinase ATM	0.0913	0.178	0.177
Trypanosoma cruzi	phosphatidylinositol kinase related protein, putative	0.0317	0.0493	0.0493
Plasmodium vivax	phosphatidylinositol 4-kinase, putative	0.0317	0.0493	0.8759
Trypanosoma brucei	phosphatidylinositol 4-kinase alpha, putative	0.0347	0.0556	0.0513
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0131	0.0091	0.0078
Entamoeba histolytica	hypothetical protein	0.0317	0.0493	0.045
Brugia malayi	hypothetical protein	0.0131	0.0091	0.0046
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0596	0.1095	0.1054
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1623	0.3313	0.3283
Leishmania major	phosphatidylinositol 4-kinase alpha, putative	0.0347	0.0556	0.0513
Treponema pallidum	peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB)	0.011	0.0045	0.5
Toxoplasma gondii	phosphatidylinositol 3- and 4-kinase	0.0347	0.0556	0.0092
Echinococcus granulosus	rhodopsin orphan GPCR	0.0131	0.0091	0.0078
Trichomonas vaginalis	PIKK family atypical protein kinase	0.472	1	1
Echinococcus granulosus	g protein coupled receptor	0.0131	0.0091	0.0078
Plasmodium vivax	phosphatidylinositol 3- and 4-kinase, putative	0.0317	0.0493	0.8759
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.014	0.011	0.0065
Schistosoma mansoni	phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K	0.0347	0.0556	0.0544
Trichomonas vaginalis	phosphatidylinositol 4-kinase, putative	0.0347	0.0556	0.0513
Echinococcus granulosus	hypothetical protein	0.0131	0.0091	0.0078
Trichomonas vaginalis	PIKK family atypical protein kinase	0.402	0.849	0.8483
Echinococcus multilocularis	neuropeptide receptor	0.0131	0.0091	0.0078
Echinococcus multilocularis	phosphatidylinositol 4,5 bisphosphate 3 kinase	0.0857	0.166	0.1649
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3763	0.7934	0.7925
Echinococcus granulosus	phosphatidylinositol 3 kinase catalytic subunit	0.0347	0.0556	0.0544
Schistosoma mansoni	adenoreceptor	0.0131	0.0091	0.0078
Trichomonas vaginalis	phosphatidylinositol kinase, putative	0.0317	0.0493	0.045
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Loa Loa (eye worm)	hypothetical protein	0.0913	0.178	0.178
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0131	0.0091	0.0078
Echinococcus granulosus	neuropeptide receptor A26	0.0131	0.0091	0.0078
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0131	0.0091	0.0091
Toxoplasma gondii	target of rapamycin (TOR), putative	0.3522	0.7413	1
Trichomonas vaginalis	PIKK family atypical protein kinase	0.2569	0.5356	0.5335
Echinococcus granulosus	PIK kinase FAT and Armadillo domain containing protein	0.0699	0.1318	0.1307
Loa Loa (eye worm)	hypothetical protein	0.0699	0.1318	0.1318
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Trypanosoma cruzi	phosphatidylinositol 3-kinase 2, putative	0.06	0.1104	0.1104
Loa Loa (eye worm)	hypothetical protein	0.0953	0.1865	0.1865
Entamoeba histolytica	hypothetical protein	0.0541	0.0976	0.0935
Brugia malayi	phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative	0.0257	0.0363	0.0319
Echinococcus multilocularis	g protein coupled receptor	0.0131	0.0091	0.0078
Trichomonas vaginalis	PIKK family atypical protein kinase	0.281	0.5877	0.5858
Echinococcus granulosus	orexin receptor type 2	0.0131	0.0091	0.0078
Trichomonas vaginalis	PIKK family atypical protein kinase	0.127	0.255	0.2516
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0131	0.0091	0.0078
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0131	0.0091	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Brugia malayi	Apoptosis regulator proteins, Bcl-2 family protein	0.0151	0.0135	0.009
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0131	0.0091	0.0078
Loa Loa (eye worm)	neuropeptide F receptor	0.0131	0.0091	0.0091
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0131	0.0091	0.0078
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.0406	0.0685	0.0643
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0131	0.0091	0.0078
Echinococcus granulosus	7TM GPCR rhodopsin	0.0131	0.0091	0.0078
Schistosoma mansoni	neuropeptide receptor	0.0131	0.0091	0.0078
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0131	0.0091	0.0078
Echinococcus granulosus	tm gpcr rhodopsin	0.0131	0.0091	0.0078
Schistosoma mansoni	growth hormone secretagogue receptor	0.0131	0.0091	0.0078
Brugia malayi	putative neuropeptide receptor	0.0131	0.0091	0.0046
Brugia malayi	G-protein coupled receptor	0.0131	0.0091	0.0046
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0131	0.0091	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Echinococcus multilocularis	serine:threonine protein kinase SMG1	0.0913	0.178	0.177
Leishmania major	phosphatidylinositol 3-kinase, putative	0.1612	0.329	0.326
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0131	0.0091	0.0078
Loa Loa (eye worm)	TYRA-2 protein	0.0131	0.0091	0.0091
Trypanosoma cruzi	phosphatidylinositol 3-related kinase, putative	0.1662	0.3398	0.3398
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Echinococcus granulosus	serine:threonine protein kinase SMG1	0.0913	0.178	0.177
Loa Loa (eye worm)	hypothetical protein	0.0151	0.0135	0.0135
Giardia lamblia	Phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.0449	0.0778	0.0737
Echinococcus granulosus	phosphatidylinositol 4 kinase beta	0.0317	0.0493	0.0481
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0131	0.0091	0.0091
Loa Loa (eye worm)	G-protein coupled receptor	0.0131	0.0091	0.0091
Echinococcus multilocularis	peptidyl prolyl cis trans isomerase FKBP4	0.011	0.0045	0.0033
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Trichomonas vaginalis	conserved hypothetical protein	0.1016	0.2003	0.1967
Echinococcus granulosus	rhodopsin orphan GPCR	0.0131	0.0091	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Echinococcus multilocularis	g protein coupled receptor	0.0131	0.0091	0.0078
Echinococcus granulosus	serotonin receptor	0.0131	0.0091	0.0078
Echinococcus multilocularis	serotonin receptor	0.0131	0.0091	0.0078
Loa Loa (eye worm)	phosphatidylinositol 3	0.0317	0.0493	0.0493
Echinococcus granulosus	neuropeptide Y receptor	0.0131	0.0091	0.0078
Echinococcus multilocularis	G protein coupled receptor 139	0.0131	0.0091	0.0078
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0131	0.0091	0.0078
Loa Loa (eye worm)	phosphatidylinositol 3	0.0798	0.1531	0.1531
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Entamoeba histolytica	protein kinase rad3, putative	0.0913	0.178	0.1743
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0131	0.0091	0.0078
Trichomonas vaginalis	PIKK family atypical protein kinase	0.472	1	1
Trypanosoma cruzi	peptidyl-prolyl cis-trans isomerase, putative	0.011	0.0045	0.0045
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0131	0.0091	0.0078
Trypanosoma cruzi	phosphatidylinositol 3-kinase, putative	0.0913	0.178	0.178
Onchocerca volvulus		0.0317	0.0493	1
Trypanosoma cruzi	phosphatidylinositol 3-related kinase, putative	0.1662	0.3398	0.3398
Trypanosoma cruzi	phosphatidylinositol 3-kinase 2, putative	0.06	0.1104	0.1104
Trichomonas vaginalis	PIKK family atypical protein kinase	0.2569	0.5356	0.5335
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0913	0.178	0.1743
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Echinococcus multilocularis	orexin receptor type 2	0.0131	0.0091	0.0078
Echinococcus multilocularis	Phosphatidylinositol 4 kinase type 2 beta	0.0317	0.0493	0.0481
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3522	0.7413	0.7401
Trypanosoma brucei	phosphatidylinositol 4-kinase, putative	0.472	1	1
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0131	0.0091	0.0078
Trypanosoma cruzi	hypothetical protein, conserved	0.009	0.0003	0.0003
Schistosoma mansoni	biogenic amine receptor	0.0131	0.0091	0.0078
Loa Loa (eye worm)	phosphatidylinositol 3	0.0317	0.0493	0.0493
Brugia malayi	Dopamine receptor	0.0131	0.0091	0.0046
Brugia malayi	GnHR receptor homolog	0.0131	0.0091	0.0046
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Trypanosoma cruzi	phosphatidylinositol 3-kinase, putative	0.0317	0.0493	0.0493
Trichomonas vaginalis	phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative	0.0406	0.0685	0.0643
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0131	0.0091	0.0078
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.06	0.1104	0.1064
Brugia malayi	sulfakinin receptor protein	0.0131	0.0091	0.0046
Echinococcus multilocularis	PIK kinase, FAT and Armadillo domain containing protein	0.0699	0.1318	0.1307
Trypanosoma cruzi	phosphatidylinositol 4-kinase alpha, putative	0.0347	0.0556	0.0556
Echinococcus granulosus	allatostatin A receptor	0.0131	0.0091	0.0078
Schistosoma mansoni	amine GPCR	0.0131	0.0091	0.0078
Trichomonas vaginalis	PIKK family atypical protein kinase	0.2822	0.5903	0.5884
Echinococcus granulosus	EGFP:Bcl2 fusion protein	0.085	0.1643	0.1632
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0131	0.0091	0.0078
Trichomonas vaginalis	conserved hypothetical protein	0.0596	0.1095	0.1054
Brugia malayi	hypothetical protein	0.0131	0.0091	0.0046
Brugia malayi	ORL1-like opioid receptor	0.0131	0.0091	0.0046
Plasmodium vivax	hypothetical protein, conserved	0.0317	0.0493	0.8759
Trichomonas vaginalis	voltage and ligand gated potassium channel, putative	0.014	0.011	0.0065
Trichomonas vaginalis	PIKK family atypical protein kinase	0.281	0.5877	0.5858
Trypanosoma brucei	phosphatidylinositol 3-kinase, putative	0.0406	0.0685	0.0643
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.06	0.1104	0.1064
Echinococcus multilocularis	DNA dependent protein kinase catalytic subunit	0.0572	0.1043	0.1032
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Trichomonas vaginalis	PIKK family atypical protein kinase	0.2565	0.5347	0.5326
Entamoeba histolytica	phosphatidylinositol 3-kinase 1, putative	0.0283	0.0419	0.0376
Echinococcus granulosus	neuropeptide s receptor	0.0131	0.0091	0.0078
Echinococcus multilocularis	potassium voltage gated channel subfamily H	0.015	0.0132	0.0119
Echinococcus multilocularis	neuropeptides capa receptor	0.0131	0.0091	0.0078
Schistosoma mansoni	biogenic amine receptor	0.0131	0.0091	0.0078
Schistosoma mansoni	histamine h1 receptor	0.0131	0.0091	0.0078
Trypanosoma cruzi	Phosphatidylinositol 3-kinase tor1	0.472	1	1
Loa Loa (eye worm)	phosphatidylinositol kinase	0.0317	0.0493	0.0493
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0131	0.0091	0.0078
Echinococcus granulosus	phosphatidylinositol 45 bisphosphate 3 kinase	0.0857	0.166	0.1649
Loa Loa (eye worm)	hypothetical protein	0.1016	0.2003	0.2003
Brugia malayi	Dopamine receptor protein 2	0.0131	0.0091	0.0046
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0131	0.0091	0.0078
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0924	0.1803	0.1766
Loa Loa (eye worm)	hypothetical protein	0.0596	0.1095	0.1095
Trypanosoma brucei	phosphatidylinositol 4-kinase, putative	0.0317	0.0493	0.045
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0317	0.0493	0.045
Echinococcus granulosus	rhodopsin orphan GPCR	0.0131	0.0091	0.0078
Schistosoma mansoni	phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K	0.0857	0.166	0.1649
Echinococcus granulosus	7tm_1 domain containing protein	0.0131	0.0091	0.0078
Echinococcus granulosus	Bcl 2 ous antagonist:killer	0.0151	0.0135	0.0123
Echinococcus multilocularis		0.0317	0.0493	0.0481
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3522	0.7413	0.7401
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3167	0.6647	0.6632
Brugia malayi	hypothetical protein	0.0131	0.0091	0.0046
Echinococcus granulosus	g protein coupled receptor	0.0131	0.0091	0.0078
Schistosoma mansoni	phosphatidylinositol 4-kinase	0.0317	0.0493	0.0481
Schistosoma mansoni	biogenic amine receptor	0.0131	0.0091	0.0078
Echinococcus granulosus	fmrfamide receptor	0.0131	0.0091	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0095	0.0012	0.0012
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0131	0.0091	0.0046
Loa Loa (eye worm)	phosphatidylinositol 4-kinase type 3 alpha isoform 1	0.0347	0.0556	0.0556
Entamoeba histolytica	phosphatidylinositol 4-kinase, putative	0.0347	0.0556	0.0513
Loa Loa (eye worm)	FKBP5 protein	0.011	0.0045	0.0045
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0131	0.0091	0.0078
Plasmodium vivax	phosphatidylinositol 4-kinase, putative	0.0317	0.0493	0.8759
Entamoeba histolytica	hypothetical protein	0.0317	0.0493	0.045
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3522	0.7413	0.7401
Schistosoma mansoni	neuropeptide f receptor 76f	0.0131	0.0091	0.0078
Trypanosoma cruzi	phosphatidylinositol 4-kinase, putative	0.0317	0.0493	0.0493
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3522	0.7413	0.7401
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3522	0.7413	0.7401
Loa Loa (eye worm)	phosphatidylinositol 3	0.0317	0.0493	0.0493
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0131	0.0091	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Echinococcus granulosus	biogenic amine 5HT receptor	0.0131	0.0091	0.0078
Toxoplasma gondii	non-specific serine/threonine protein kinase	0.1016	0.2003	0.2182
Leishmania major	target of rapamycin (TOR) kinase 1, putative	0.472	1	1
Schistosoma mansoni	opsin-like receptor	0.0131	0.0091	0.0078
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0131	0.0091	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0131	0.0091	0.0046
Trypanosoma cruzi	phosphatidylinositol 4-kinase, putative	0.0317	0.0493	0.0493
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Schistosoma mansoni	immunophilin FK506 binding protein FKBP12	0.011	0.0045	0.0033
Trichomonas vaginalis	phopsphatidylinositol 3-kinase, drosophila, putative	0.06	0.1104	0.1064
Plasmodium falciparum	phosphatidylinositol 3- and 4-kinase, putative	0.0317	0.0493	0.8759
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Trypanosoma cruzi	phosphatidylinositol kinase related protein, putative	0.0596	0.1095	0.1095
Echinococcus multilocularis	neuropeptide Y receptor	0.0131	0.0091	0.0078
Schistosoma mansoni	immunophilin	0.011	0.0045	0.0033
Leishmania major	phosphatidylinositol kinase related protein, putative	0.0317	0.0493	0.045
Brugia malayi	hypothetical protein	0.0131	0.0091	0.0046
Entamoeba histolytica	phosphatidylinositol 3-kinase, putative	0.0541	0.0976	0.0935
Echinococcus granulosus	rhodopsin orphan GPCR	0.0131	0.0091	0.0078
Echinococcus granulosus	biogenic amine 5HT receptor	0.0131	0.0091	0.0078
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0131	0.0091	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0131	0.0091	0.0078
Entamoeba histolytica	Phosphatidylinositol 3- and 4-kinase family	0.0924	0.1803	0.1766
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0131	0.0091	0.0078
Brugia malayi	hypothetical protein	0.0131	0.0091	0.0046
Schistosoma mansoni	hypothetical protein	0.0131	0.0091	0.0078
Echinococcus multilocularis	EGFP:Bcl2 fusion protein	0.085	0.1643	0.1632
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0131	0.0091	0.0078
Mycobacterium ulcerans	FK-506 binding protein, peptidyl-prolyl cis-trans isomerase	0.011	0.0045	0.5
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0131	0.0091	0.0078
Trypanosoma cruzi	FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative	0.011	0.0045	0.0045
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0131	0.0091	0.0078
Brugia malayi	Dopamine receptor protein 1	0.0131	0.0091	0.0046
Plasmodium falciparum	phosphatidylinositol 4-kinase	0.0317	0.0493	0.8759
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0131	0.0091	0.0046
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3522	0.7413	0.7401
Schistosoma mansoni	fkbp-rapamycin associated protein	0.0913	0.178	0.177
Echinococcus multilocularis	phosphatidylinositol 4 kinase alpha	0.0347	0.0556	0.0544
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0131	0.0091	0.0078
Brugia malayi	hypothetical protein	0.0131	0.0091	0.0046
Trichomonas vaginalis	phosphatidylinositol 3-kinase catalytic subunit gamma, putative	0.06	0.1104	0.1064
Entamoeba histolytica	hypothetical protein	0.0913	0.178	0.1743
Brugia malayi	Melatonin receptor type 1A	0.0131	0.0091	0.0046
Schistosoma mansoni	neuropeptide F-like receptor	0.0131	0.0091	0.0078
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0498	0.0882	0.0841
Echinococcus granulosus	somatostatin receptor	0.0131	0.0091	0.0078
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0131	0.0091	0.0091
Loa Loa (eye worm)	hypothetical protein	0.0498	0.0882	0.0882
Schistosoma mansoni	hypothetical protein	0.0151	0.0135	0.0123
Schistosoma mansoni	immunophilin	0.011	0.0045	0.0033
Trichomonas vaginalis	PIKK family atypical protein kinase	0.2565	0.5347	0.5326
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0317	0.0493	0.045
Echinococcus multilocularis	sex peptide receptor	0.0131	0.0091	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Schistosoma mansoni	bcl-2 homologous antagonist/killer (bak)	0.0151	0.0135	0.0123
Loa Loa (eye worm)	hypothetical protein	0.0317	0.0493	0.0493
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0131	0.0091	0.0078
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3763	0.7934	0.7925
Trichomonas vaginalis	PIKK family atypical protein kinase	0.2569	0.5356	0.5335
Trichomonas vaginalis	phopsphatidylinositol 3-kinase, drosophila, putative	0.0317	0.0493	0.045
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0131	0.0091	0.0078
Trichomonas vaginalis	PIKK family atypical protein kinase	0.0913	0.178	0.1743
Trypanosoma brucei	phosphatidylinositol 3-related kinase, putative	0.1623	0.3313	0.3283
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0131	0.0091	0.0078
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3763	0.7934	0.7925
Echinococcus granulosus	tm gpcr rhodopsin	0.0131	0.0091	0.0078
Trypanosoma brucei	phosphatidylinositol 3-kinase tor, putative	0.2226	0.4616	0.4591
Leishmania major	phosphatidylinositol 3-kinase, putative	0.0347	0.0556	0.0513
Brugia malayi	hypothetical protein	0.0131	0.0091	0.0046
Trichomonas vaginalis	phosphatidylinositol 3-kinase class, putative	0.0509	0.0907	0.0866
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0131	0.0091	0.0078
Echinococcus granulosus	rhodopsin orphan GPCR	0.0131	0.0091	0.0078
Echinococcus multilocularis	fk506 binding protein	0.011	0.0045	0.0033
Loa Loa (eye worm)	neuropeptide F receptor	0.0131	0.0091	0.0091
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0131	0.0091	0.0091
Toxoplasma gondii	FATC domain-containing protein	0.0913	0.178	0.186
Loa Loa (eye worm)	melatonin receptor type 1A	0.0131	0.0091	0.0091
Onchocerca volvulus		0.0317	0.0493	1
Loa Loa (eye worm)	phosphatidylinositol 3	0.1623	0.3313	0.3313
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0406	0.0685	0.0643
Trichomonas vaginalis	PIKK family atypical protein kinase	0.2569	0.5356	0.5335
Giardia lamblia	Phosphatidylinositol 4-kinase	0.0317	0.0493	0.045
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0913	0.178	0.1743
Entamoeba histolytica	phosphatidylinositol 3-kinase 3, putative	0.0317	0.0493	0.045
Trichomonas vaginalis	phosphatidylinositol 3-kinase class, putative	0.0347	0.0556	0.0513
Entamoeba histolytica	FKBP-rapamycin associated protein (FRAP), putative	0.472	1	1
Leishmania major	phosphatidylinositol kinase, putative	0.0317	0.0493	0.045
Trypanosoma cruzi	phosphatidylinositol 3-kinase vps34-like	0.0406	0.0685	0.0685
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Brugia malayi	neuropeptide F receptor	0.0131	0.0091	0.0046
Schistosoma mansoni	hypothetical protein	0.0131	0.0091	0.0078
Brugia malayi	phosphatidylinositol 4-kinase, catalytic, alpha polypeptide	0.0347	0.0556	0.0513
Entamoeba histolytica	hypothetical protein	0.0317	0.0493	0.045
Brugia malayi	follicle stimulating hormone receptor	0.0131	0.0091	0.0046
Schistosoma mansoni	voltage-gated potassium channel	0.0164	0.0161	0.0149
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3064	0.6424	0.6408
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0131	0.0091	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Brugia malayi	RE15519p	0.0131	0.0091	0.0046
Echinococcus granulosus	peptidyl prolyl cis trans isomerase FKBP4	0.011	0.0045	0.0033
Trypanosoma brucei	phosphatidylinositol 3-kinase, putative	0.1612	0.329	0.326
Mycobacterium leprae	conserved hypothetical protein	0.0317	0.0493	0.5
Echinococcus granulosus	peptidyl prolyl cis trans isomerase FKBP1A	0.011	0.0045	0.0033
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0131	0.0091	0.0078
Schistosoma mansoni	phosphatidylinositol 4-kinase	0.0347	0.0556	0.0544
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Brugia malayi	putative neuropeptide receptor NPR1	0.0131	0.0091	0.0046
Echinococcus multilocularis	FKBP12 rapamycin complex associated protein	0.472	1	1
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0131	0.0091	0.0078
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0131	0.0091	0.0078
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0131	0.0091	0.0078
Schistosoma mansoni	amine GPCR	0.0131	0.0091	0.0078
Loa Loa (eye worm)	FKBP-type peptidyl-prolyl cis-trans isomerase-12	0.011	0.0045	0.0045
Brugia malayi	G protein-coupled receptor F59B2.13	0.0131	0.0091	0.0046
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0131	0.0091	0.0078
Leishmania major	hypothetical protein, conserved	0.0408	0.0688	0.0646
Leishmania major	phosphatidylinositol 3-related kinase, putative	0.1623	0.3313	0.3283
Trypanosoma cruzi	FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative	0.011	0.0045	0.0045
Trypanosoma cruzi	Phosphatidylinositol 3-kinase tor2	0.472	1	1
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Trichomonas vaginalis	PIKK family atypical protein kinase	0.2822	0.5903	0.5884
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0131	0.0091	0.0078
Echinococcus multilocularis	phosphatidylinositol 3 and 4 kinase	0.1662	0.3398	0.339
Loa Loa (eye worm)	apoptosis regulator protein	0.0151	0.0135	0.0135
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0131	0.0091	0.0078
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0131	0.0091	0.0078
Echinococcus granulosus	neuropeptides capa receptor	0.0131	0.0091	0.0078
Echinococcus granulosus	neuropeptide receptor	0.0131	0.0091	0.0078
Trichomonas vaginalis	phosphatidylinositol 3-kinase class, putative	0.0406	0.0685	0.0643
Schistosoma mansoni	ataxia telangiectasia mutated (atm)-related	0.472	1	1
Schistosoma mansoni	phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K	0.0406	0.0685	0.0673
Schistosoma mansoni	amine GPCR	0.0131	0.0091	0.0078
Brugia malayi	hypothetical protein	0.0131	0.0091	0.0046
Trichomonas vaginalis	phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative	0.0509	0.0907	0.0866
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0317	0.0493	0.045
Giardia lamblia	GTOR	0.472	1	1
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0131	0.0091	0.0078
Plasmodium vivax	phosphatidylinositol 3-kinase, putative	0.0347	0.0556	1
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.1662	0.3398	0.3368
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0131	0.0091	0.0046
Echinococcus multilocularis	phosphatidylinositol 4 phosphate 3 kinase C2	0.0498	0.0882	0.0871
Schistosoma mansoni	phosphatidylinositol 3-and 4-kinase	0.1662	0.3398	0.339
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Echinococcus granulosus	g protein coupled receptor	0.0131	0.0091	0.0078
Giardia lamblia	Hypothetical protein	0.0317	0.0493	0.045
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3763	0.7934	0.7925
Trichomonas vaginalis	PIKK family atypical protein kinase	0.1612	0.329	0.326
Mycobacterium tuberculosis	Conserved hypothetical protein	0.0317	0.0493	0.5
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Echinococcus granulosus	DNA dependent protein kinase catalytic subunit	0.0572	0.1043	0.1032
Loa Loa (eye worm)	voltage and ligand gated potassium channel	0.015	0.0132	0.0132
Plasmodium falciparum	phosphatidylinositol 3-kinase	0.0347	0.0556	1
Brugia malayi	Phosphatidylinositol 3- and 4-kinase family protein	0.0317	0.0493	0.045
Trypanosoma brucei	phosphatidylinositol kinase related protein, putative	0.0913	0.178	0.1743
Trichomonas vaginalis	PIKK family atypical protein kinase	0.3763	0.7934	0.7925
Schistosoma mansoni	hypothetical protein	0.0317	0.0493	0.0481
Trypanosoma cruzi	phosphatidylinositol kinase related protein, putative	0.0913	0.178	0.178
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091
Toxoplasma gondii	phosphatidylinositol 3- and 4-kinase	0.0347	0.0556	0.0092
Trypanosoma brucei	target of rapamycin kinase 3, putative	0.3767	0.7943	0.7933
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0131	0.0091	0.0078
Echinococcus granulosus	g-protein coupled receptor	0.0131	0.0091	0.0078
Schistosoma mansoni	hypothetical protein	0.0151	0.0135	0.0123
Echinococcus multilocularis	Phosphatidylinositol 4 kinase type 2 beta	0.0317	0.0493	0.0481
Brugia malayi	neuropeptide F receptor	0.0131	0.0091	0.0046
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0131	0.0091	0.0078
Loa Loa (eye worm)	hypothetical protein	0.0131	0.0091	0.0091

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL2009047

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1635408